• Atrial Fibrillation
    • Isabelle C Van Gelder
    • Isabelle C Van Gelder: Influence Statistics

      Isabelle C Van Gelder

      Isabelle C Van Gelder

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      Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. | University of Groningen, University of Groningen Medical ...

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      Isabelle C Van Gelder:Expert Impact

      Concepts for whichIsabelle C Van Gelderhas direct influence:Atrial fibrillation,Heart failure,Rate control,Sinus rhythm,Rhythm control,Heart rate,Patients atrial fibrillation,Persistent atrial fibrillation.

      Isabelle C Van Gelder:KOL impact

      Concepts related to the work of other authors for whichfor which Isabelle C Van Gelder has influence:Atrial fibrillation,Heart failure,Catheter ablation,Sinus rhythm,Ischemic stroke,Oral anticoagulants,Major bleeding.

      KOL Resume for Isabelle C Van Gelder


      Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

      University of Groningen, University of Groningen Medical Center, Gronigen, The Netherlands (I.C.V.G.).


      University of Groningen, University Medical Center Groningen, Groningen, Netherlands


      University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

      Univ Med Cntr Groningen, Groningen


      Cardiology Department, University of Groningen, University Medical Center Groningen, Thoraxcenter, Groningen, The Netherlands


      Department of Cardiology, Cardiology Research Unit, Odense University Hospital, University of Southern Denmark Odense, Denmark.

      University Medical Center Groningen, Cardiology, Groningen, Netherlands


      Department of Cardiology, Thoraxcenter, University of Groningen, University Medical Center Groningen, Hanzeplein 1, GZ 9713, Groningen, The Netherlands

      From Heart Research Institute, Charles Perkins Centre, and Concord Hospital Cardiology, University of Sydney, Australia (B.F.); St Georges Hospital, London, UK (J.C.); Johns Hopkins University, Baltimore, MD (H.C.); Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada (J.S.H., D.C.); Karolinska Institute, Stockholm, Sweden (M.R., J.E., L.F., E.S.); The Shanghai Institute of Hypertension, Ruijin Hospital, Jiaotong University School of Medicine, China (J.W.); Brigham...


      Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands.

      The disclosure forms of all experts involved in the development of these guidelines are available on the ESC website

      Department of Cardiology, Thoraxcenter, University of Groningen, University Medical Center Groningen, Groningen, Netherlands


      Department of Cardiology, University Medical Center Groningen, 9711 RB Groningen, Netherlands


      Department of Cardiology, Thoraxcenter, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands

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      Sample of concepts for which Isabelle C Van Gelder is among the top experts in the world.
      Concept World rank
      septal pacing life #1
      serial antiarrhythmic #1
      magnitude reverse remodelling #1
      43 33 years #1
      cmr tag cmrft #1
      illness desmin #1
      comparison ste #1
      reverse remodelling nidcm #1
      p002 shocks #1
      antiarrhythmic drugs type #1
      90 bpm #1
      ste icc #1
      supraventricular tachycardias svts #1
      sex differences pharmacodynamics #1
      afonset #1
      matched study surgical #1
      epicardial pvi #1
      systolic stretch icc #1
      ecv management #1
      fibrillation progression #1
      pharmacological rhythm control #1
      tomtec srssept #1
      paroxysmal computed tomography #1
      atrial remodeling induction #1
      firstonset svt january #1
      icd therapy tof #1
      shocks primary #1
      khairy colleagues #1
      efficacy permanent #1
      overlooked prognostic tool #1
      firstonset svt #1
      villain bystander #1
      patients pv anatomy #1
      ste lvesv #1
      inadequate inr admission #1
      10ms increase p0008 #1
      arrhythmias thyroid #1
      atrial fibrillation insight #1
      srssept ssi #1
      vbi oac #1
      comparable outcome patients #1
      ait subclinical #1
      iii surgery patients #1
      tomtec −77 ± #1
      nsvt shocks #1
      clinical parameters scd #1
      treatment rate control #1
      cacs increased risk #1
      nonlaaa #1
      january firstonset svt #1
      Sign-in to see all concepts, it's free!

      Prominent publications by Isabelle C Van Gelder

      KOL-Index: 14588

      BACKGROUND: The combination of left bundle branch block (LBBB) morphology and QRS duration is currently used to select patients for cardiac resynchronization therapy (CRT). These parameters, however, have limitations. This study evaluates the value of QRS area compared with that of QRS duration and morphology in the association with clinical and echocardiographic outcomes in a large cohort of CRT patients.

      METHODS: A retrospective multicentre study was conducted in 1492 CRT patients. ...

      Known for Qrs Area | Cardiac Resynchronization | Patients Crt | Bundle Branch | Echocardiographic Response
      KOL-Index: 14341

      BACKGROUND: One quarter of strokes are of unknown cause, and subclinical atrial fibrillation may be a common etiologic factor. Pacemakers can detect subclinical episodes of rapid atrial rate, which correlate with electrocardiographically documented atrial fibrillation. We evaluated whether subclinical episodes of rapid atrial rate detected by implanted devices were associated with an increased risk of ischemic stroke in patients who did not have other evidence of atrial ...

      Known for Atrial Fibrillation | Systemic Embolism | 3 Months | Hazard Ratio | Ischemic Stroke Patients
      KOL-Index: 14282

      OBJECTIVES: We studied the influence of rate control or rhythm control in patients with persistent atrial fibrillation (AF) on quality of life (QoL).

      BACKGROUND: Atrial fibrillation may cause symptoms like fatigue and dyspnea. This can impair QoL. Treatment of AF with either rate or rhythm control may influence QoL.

      METHOD: Quality of life was assessed in patients included in the Rate Control Versus Electrical Cardioversion for Persistent Atrial Fibrillation (RACE) study (rate vs. rhythm ...

      Known for Rhythm Control | Life Qol | Persistent Atrial | Baseline Study | Electrical Cardioversion
      KOL-Index: 13862

      OBJECTIVES: The purpose of this study was to evaluate left ventricular function and atrial and ventricular diameters in patients with persistent atrial fibrillation (AF) treated with rate or rhythm control.

      BACKGROUND: Restoration of sinus rhythm in patients with persistent AF may improve left ventricular function and reduce atrial dimensions. Adequate rate control in AF may preserve ventricular function.

      METHODS: In 335 patients included in the RAte Control versus Electrical ...

      Known for Ventricular Function | Rate Control | Persistent Atrial Fibrillation | Electrical Cardioversion | Sinus Rhythm Patients
      KOL-Index: 13826

      BACKGROUND: Maintenance of sinus rhythm is the main therapeutic goal in patients with atrial fibrillation. However, recurrences of atrial fibrillation and side effects of antiarrhythmic drugs offset the benefits of sinus rhythm. We hypothesized that ventricular rate control is not inferior to the maintenance of sinus rhythm for the treatment of atrial fibrillation.

      METHODS: We randomly assigned 522 patients who had persistent atrial fibrillation after a previous electrical cardioversion ...

      Known for Rhythm Control | Atrial Fibrillation | Primary Point | Patients Rate | Death Cardiovascular
      KOL-Index: 13685

      BACKGROUND: Despite improvements in the management of atrial fibrillation, patients with this condition remain at increased risk for cardiovascular complications. It is unclear whether early rhythm-control therapy can reduce this risk.

      METHODS: In this international, investigator-initiated, parallel-group, open, blinded-outcome-assessment trial, we randomly assigned patients who had early atrial fibrillation (diagnosed ≤1 year before enrollment) and cardiovascular conditions to receive ...

      Known for Early Rhythm | Atrial Fibrillation | Control Therapy | Patients Usual | Ventricular Function
      KOL-Index: 13363

      OBJECTIVES: This study sought to study the association of atrial fibrillation (AF) with exercise capacity, left ventricular filling pressure, natriuretic peptides, and left atrial size in heart failure with preserved ejection fraction (HFpEF).

      BACKGROUND: The diagnosis of HFpEF in patients with AF remains a challenge because both contribute to impaired exercise capacity, and increased natriuretic peptides and left atrial volume.

      METHODS: We studied 94 patients with symptomatic heart ...

      Known for Atrial Volume | Natriuretic Peptides | Heart Failure | Exercise Capacity | Sinus Rhythm
      KOL-Index: 13141

      Abnormalities in intracellular Ca2+ handling play a crucial role in the pathogenesis of heart failure. The reduced capacity of failing human myocardium to restore low resting Ca2+ levels during diastole has been explained by the impairment of Ca2+ uptake into the sarcoplasmic reticulum (SR) via the SR Ca2+ATPase. It is unclear whether Ca2+ATPase function, protein levels, and mRNA steady-state levels correspond to one other, and whether the cause of heart failure, namely idiopathic ...

      Known for Protein Levels | Sarcoplasmic Reticulum | Heart Failure | Dilated Cardiomyopathy | Patients Dcm
      KOL-Index: 13133

      Aims: Atrial fibrillation (AF) is a progressive disease. Targeted therapy of underlying conditions refers to interventions aiming to modify risk factors in order to prevent AF. We hypothesised that targeted therapy of underlying conditions improves sinus rhythm maintenance in patients with persistent AF.

      Methods and results: We randomized patients with early persistent AF and mild-to-moderate heart failure (HF) to targeted therapy of underlying conditions or conventional therapy. Both ...

      Known for Underlying Conditions | Sinus Rhythm | Atrial Fibrillation | Race 3 Trial | Cardiac Rehabilitation
      KOL-Index: 13107

      BACKGROUND: There is a marked lack of evidence on the optimal prevention of ischaemic stroke and other thromboembolic events in patients with non-valvular atrial fibrillation and a recent intracerebral haemorrhage during treatment with oral anticoagulation. These patients are currently treated with oral anticoagulants, antiplatelet drugs, or no antithrombotic treatment, depending on personal and institutional preferences. Compared with warfarin, the direct oral anticoagulant apixaban ...

      Known for Intracerebral Haemorrhage | Patients Atrial Fibrillation | Oral Anticoagulation | Antithrombotic Drugs | Risk Stroke
      KOL-Index: 13059

      Parameters using myocardial strain analysis may predict response to cardiac resynchronization therapy (CRT). As the agreement between currently available strain imaging modalities is unknown, three different modalities were compared. Twenty-seven CRT-candidates, prospectively included in the MARC study, underwent cardiac magnetic resonance (CMR) imaging and echocardiographic examination. Left ventricular (LV) circumferential strain was analysed with CMR tagging (CMR-TAG), CMR feature ...

      Known for Strain Imaging | Cmrft Ste | Tracking Echocardiography | Cmr Tagging | Dyssynchrony Discoordination
      KOL-Index: 12979

      OBJECTIVES: The aim of this study was to investigate the influence of rate control on quality of life (QOL).

      BACKGROUND: The RACE II (Rate Control Efficacy in Permanent Atrial Fibrillation II) trial showed that lenient rate control is not inferior to strict rate control in terms of cardiovascular morbidity and mortality. The influence of stringency of rate control on QOL is unknown.

      METHODS: In RACE II, a total of 614 patients with permanent atrial fibrillation (AF) were randomized to ...

      Known for Rate Control | Atrial Fibrillation | Life Qol | Cardiovascular Morbidity | Severity Scale
      KOL-Index: 12766

      BACKGROUND: Among patients with implantable pacemakers and defibrillators, subclinical atrial fibrillation (SCAF) is associated with an increased risk of stroke; however, there is limited understanding of their temporal relationship.

      METHODS AND RESULTS: The Asymptomatic Atrial Fibrillation and Stroke Evaluation in Pacemaker Patients and the Atrial Fibrillation Reduction Atrial Pacing Trial (ASSERT) enrolled 2580 pacemaker and defibrillator patients aged ≥65 years with a history of ...

      Known for Temporal Relationship | Atrial Fibrillation | Scaf Stroke | Systemic Embolism | Pacemaker Patients
      KOL-Index: 12765

      BACKGROUND: Primary dysrhythmias other than those associated with the long QT syndrome, are increasingly recognized. One of these are represented by patients with a history of resuscitation from cardiac arrest but without any structural heart disease. These patients exhibit a distinct electrocardiographic (ECG) pattern consisting of a persistent ST-segment elevation in the right precordial leads often but not always accompanied by a right bundle branch block (Brugada syndrome). This ...

      Known for Sodium Channel | Brugada Syndrome | Scn5a Gene | Missense Mutations | Xenopus Oocytes

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      Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. | University of Groningen, University of Groningen Medical Center, Gronigen, The Netherlands (I.C.V.G.). | University of Groningen, Un

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