Prominent publications by Giuseppeli Giuseppe

KOL Index score: 21580

BACKGROUND: The study is aimed at evaluating the performance of the predictive model ROMA (Risk of Ovarian Malignancy Algorithm), which utilizes the combination of human epididymis protein 4 (HE4) and CA125 values to assess the risk of epithelial ovarian cancer (EOC) in women with a pelvic mass.

METHODS: One hundred and four women diagnosed with a pelvic mass (55 EOC and 49 benign cases) and scheduled to have surgery were enrolled, along with 49 healthy females. Preoperative serum ...

Also Ranks for: Pelvic Mass |  epithelial ovarian |  ca125 roma |  95 he4 |  sensitivity specificity
KOL Index score: 15217

BACKGROUND: European questionnaire survey was conducted by the European Federation of Clinical Chemistry and Laboratory Medicine Working Group for the Preanalytical Phase (EFLM WG-PA) to assess how phlebotomy is performed in EFLM countries, including differences in personnel, level of education and skills, and to investigate the presence and compliance of national phlebotomy guidelines on this matter.

METHODS: A questionnaire was constructed containing questions elucidating different ...

Also Ranks for: Laboratory Medicine |  european federation |  national guidelines |  education training |  clinical chemistry
KOL Index score: 12276

Laboratory diagnostics develop through different phases that span from test ordering (pre-preanalytical phase), collection of diagnostic specimens (preanalytical phase), sample analysis (analytical phase), results reporting (postanalytical phase) and interpretation (post-postanalytical phase). Although laboratory medicine seems less vulnerable than other clinical and diagnostic areas, the chance of errors is not negligible and may adversely impact on quality of testing and patient ...

Also Ranks for: Preanalytical Phase |  laboratory medicine |  european federation |  clinical chemistry |  test request
KOL Index score: 12184

Neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and platelet count (PC) were shown to be prognostic in several solid malignancies. We analysed 603 R0 resected patients to assess whether NLR, PLR and PC correlate with other well-known prognostic factors and survival of patients with colorectal cancer (CRC). Receiver operating characteristic (ROC) curve analysis was performed to define cut-off values for high and low ratios of these indices. Univariate and ...

Also Ranks for: Colorectal Cancer |  platelet count |  nlr plr |  lymphocyte ratio |  crc patients
KOL Index score: 12115

Background As coronavirus disease 2019 (COVID-19) pandemic rages on, there is urgent need for identification of clinical and laboratory predictors for progression towards severe and fatal forms of this illness. In this study we aimed to evaluate the discriminative ability of hematologic, biochemical and immunologic biomarkers in patients with and without the severe or fatal forms of COVID-19. Methods An electronic search in Medline (PubMed interface), Scopus, Web of Science and China ...

Also Ranks for: Severe Illness |  coronavirus disease covid19 |  disease 2019 |  serum ferritin |  laboratory abnormalities
KOL Index score: 12017

An early diagnosis is crucial for effective triage and management of patients with suspected acute myocardial infarction (AMI). Although troponin testing is the cornerstone of diagnosis, the sensitivity of this biomarker is still suboptimal at patient admission. The heart-type fatty acid binding protein (H-FABP) is an early and sensitive biomarker of myocardial ischemia, whose appropriate setting is in combination with troponin testing. We performed a systematic review and meta-analysis ...

Also Ranks for: Early Diagnosis |  fatty acid |  binding protein |  acute myocardial |  sensitivity troponin
KOL Index score: 11957

The knowledge of error rates is essential in all clinical laboratories as it enables them to accurately identify their risk level, and compare it with those of other laboratories in order to evaluate their performance in relation to the State-of-the-Art (i.e. benchmarking) and define priorities for improvement actions. Although no activity is risk free, it is widely accepted that the risk of error is minimized by the use of Quality Indicators (QIs) managed as a part of laboratory ...

Also Ranks for: Patient Safety |  quality indicators |  laboratory medicine |  clinical laboratories |  error rates
KOL Index score: 11947

Aims/hypothesisNon-alcoholic fatty liver disease (NAFLD) is associated with an increased risk of cardiovascular disease in type 2 diabetes. Currently, there is a lack of information on associations between NAFLD and microvascular complications of diabetes. We assessed the associations between NAFLD and both chronic kidney disease (CKD) and retinopathy in a large cohort of type 2 diabetic individuals using a cross-sectional design.MethodsPrevalence rates of retinopathy (by ophthalmoscopy) ...

Also Ranks for: Increased Prevalence |  2 diabetic |  chronic kidney disease |  ckd retinopathy |  fatty liver
KOL Index score: 11307

von Willebrand factor (VWF) is a large adhesive multimeric protein involved in hemostasis. The larger the size (or number of VWF multimers), the greater the functionality of the protein. A deficiency or defect of VWF can lead to von Willebrand disease (VWD) and cause bleeding. Conversely, an increase in VWF may create an environment that promotes thrombosis. ADAMS-13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13), sometimes called VWF-cleaving ...

Also Ranks for: Vwf Adamts13 |  willebrand factor |  severe deficiency |  protein covid19 |  humans sars
KOL Index score: 10864

OBJECTIVES: To document the relation between serum creatinine concentration and body mass index in elite athletes from five different sports, and to study potential differences among athletes performing different sports with different features and requirements.

METHODS: Before the start of the competitive season, serum creatinine was measured in 151 elite athletes from five different sports: rugby (n = 44), soccer (n = 27), alpine skiing (n = 34), sailing (n = 22), cycling (n = 24). ...

Also Ranks for: Serum Creatinine |  elite athletes |  sport disciplines |  body mass bmi |  start training
KOL Index score: 10646

Bone mass can be viewed as the net product of two counteracting metabolic processes, bone formation and bone resorption, which allow the skeleton to carry out its principal functions: mechanical support of the body, calcium dynamic deposition and haemopoiesis. Besides radiological methods, several blood and urinary molecules have been identified as markers of bone metabolic activity for estimating the rates and direction of the biological activities governing bone turnover. The ...

Also Ranks for: Bone Metabolism |  sports medicine |  exercise markers |  weight bearing |  physical activity
KOL Index score: 10590

Aims/hypothesisNon-alcoholic fatty liver disease (NAFLD) is associated with an increased prevalence of chronic kidney disease (CKD) and retinopathy in patients with type 2 diabetes. Information on this issue is lacking for type 1 diabetes. We evaluated whether NAFLD is associated with increased prevalence of retinopathy and CKD in type 1 diabetic patients.MethodsAll type 1 diabetic patients (n = 202) who regularly attended our diabetes clinic and did not have any clinical evidence of ...

Also Ranks for: Increased Prevalence |  type 1 |  diabetic patients |  kidney disease |  fatty liver

Key People For Laboratory Medicine

Top KOLs in the world
Plebani *******
laboratory medicine pancreatic cancer quality indicators
Giuseppeli ********
laboratory medicine emergency department venous thromboembolism
Mauro **********
creatine kinase myocardial infarction cardiac troponin
Ferruccio ********
reference procedure catalytic concentration biological variation
Sverre ********
biological variation blood glucose general practice
Michael ********
fatty acids cystic fibrosis ethanol intake

Giuseppeli Giuseppe:Expert Impact

Concepts for whichGiuseppeli Giuseppehas direct influence:Laboratory medicine,  Emergency department,  Venous thromboembolism,  Laboratory testing,  Preanalytical phase,  Cardiovascular disease.

Giuseppeli Giuseppe:KOL impact

Concepts related to the work of other authors for whichfor which Giuseppeli Giuseppe has influence:Venous thromboembolism,  Cardiovascular disease,  Atrial fibrillation,  Fatty liver,  Physical activity,  Cell distribution width,  Oxidative stress.



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Section of Clinical Biochemistry, University Hospital of Verona, 37134 Verona, Italy | Section of Clinical Biochemistry, University of Verona, 37126 Verona, Italy;, | Section of Clinical Biochemistry, University of Verona, 371