• Disease
  • Ulcerative
  • Ulcerative Colitis
  • Robin Susan Mcleod

    Prominent publications by Robin Susan McLeod

    KOL Index score: 17318

    PURPOSE: This study was designed to determine the outcome of patients with Crohn's disease and indeterminate colitis who have an ileal pouch-anal anastomosis.

    METHODS: Between 1982 and 2001, 1,270 patients underwent a restorative proctocolectomy at the Mount Sinai Hospital: 1,135 had ulcerative colitis, 36 had Crohn's disease, 21 had indeterminate colitis, and 78 had another diagnosis. Perioperative data were collected prospectively. Functional outcomes were assessed with a 35-question ...

    Also Ranks for: Indeterminate Colitis |  crohns disease |  patients crohn |  ileal pouch |  restorative proctocolectomy
    KOL Index score: 17125

    QUESTIONS: Should surgery be considered for colorectal cancer (crc) patients who have liver metastases plus (a) pulmonary metastases, (b) portal nodal disease, or (c) other extrahepatic metastases (ehms)?What is the role of chemotherapy in the surgical management of crc with liver metastases in (a) patients with resectable disease in the liver, or (b) patients with initially unresectable disease in the liver that is downsized with chemotherapy ("conversion")?What is the role of liver ...

    Also Ranks for: Liver Resection |  perioperative chemotherapy patients |  colorectal cancer metastases |  postoperative chemotherapy |  metastatic disease
    KOL Index score: 16608

    PURPOSE: The purpose of this study was to examine the association between coping behavior at the time of surgery and inflammatory bowel disease-related quality of life after surgery. We also investigated the relationship between perceived social support and both coping style and postsurgical quality of life. Finally, the value of the Medical Outcomes Study Social Support Scale for preoperative screening was assessed.

    METHODS: Eighty-six subjects who had surgery during a 12-month period ...

    Also Ranks for: Social Support |  inflammatory bowel |  quality life |  maladaptive coping |  disease questionnaire
    KOL Index score: 15621

    PURPOSE: The aim of this study was to evaluate the surgical complications and long-term outcome and assess the functional results and quality of life after ileorectal anastomosis and ileal pouch-anal anastomosis in patients with familial adenomatous polyposis.

    METHODS: From 1980 to 1997, 131 patients with familial adenomatous polyposis were operated on or were followed up or both at the Familial Gastrointestinal Cancer Registry at Mount Sinai Hospital. Demographic and operative data were ...

    Also Ranks for: Ileorectal Anastomosis |  ileal pouch |  familial adenomatous polyposis |  quality life |  functional outcome
    KOL Index score: 15049

    PURPOSE: This was a multicenter, randomized, controlled trial to compare the effectiveness of topical nitroglycerin with internal sphincterotomy in the treatment of chronic anal fissure.

    METHODS: Patients with symptomatic chronic anal fissures were randomly assigned to 0.25 percent nitroglycerin tid or internal sphincterotomy. Both groups received stool softeners and fiber supplements and were assessed at six weeks and six months.

    RESULTS: Ninety patients were accrued, but 8 were ...

    Also Ranks for: Internal Sphincterotomy |  topical nitroglycerin |  chronic anal fissure |  percent patients |  complete healing
    KOL Index score: 12291

    OBJECTIVE: To determine the incidence of small bowel obstruction (SBO), to identify risk factors for its development, and to determine the most common sites of adhesions causing SBO in patients undergoing ileal pouch-anal anastomosis (IPAA).

    METHODS: All patients undergoing IPAA at Mount Sinai Hospital were included. Data were obtained from the institution's database, patient charts, and a mailed questionnaire. SBO was based on clinical, radiologic, and surgical findings. Early SBO was ...

    Also Ranks for: Small Bowel Obstruction |  sbo patients |  ileal pouch |  anal anastomosis |  10 years
    KOL Index score: 12273

    PURPOSE: The aim of this study was to review the functional outcome in 20 patients with familial adenomatous polyposis and ulcerative colitis who were converted from ileorectal anastomosis to ileal pouch-anal anastomosis.

    METHODS: From 1985 to 1997, 12 patients with familial adenomatous polyposis (5 males; mean age, 39.1 years) and 8 patients with ulcerative colitis (5 males; mean age, 36.7 years) underwent conversion from ileorectal anastomosis to ileal pouch-anal anastomosis. Clinical ...

    Also Ranks for: Ileorectal Anastomosis |  familial adenomatous polyposis |  ileal pouch |  ulcerative colitis |  functional outcome
    KOL Index score: 11996

    BACKGROUND & AIMS: Linkage data derived from genome-wide scans of inflammatory bowel disease (IBD) sibling-pair families have identified 4 loci on chromosomes 3, 7, 12, and 16 as potential sites for IBD susceptibility genes. The aim of this study was to investigate whether linkage analysis of another independently collected set of sibling pairs with IBD would provide further evidence of linkage between these previously reported loci and IBD.

    METHODS: Using the MAPMAKER/SIBS program, the ...

    Also Ranks for: Chromosomes Human |  inflammatory bowel |  linkage ibd |  pair 12 |  3 7
    KOL Index score: 11896

    PURPOSE: Ulcerative colitis is a risk factor for colorectal cancer. Restorative proctocolectomy with ileal pouch-anal anastomosis is a standard surgical management of patients with ulcerative colitis who have cancer or dysplasia, but the oncologic risk of stapled anastomosis vs mucosectomy with handsewn anastomosis is debated. We compare the risk of new cancer or recurrence in the pouch or rectal cuff in patients with ulcerative colitis undergoing stapled anastomosis vs mucosectomy with ...

    Also Ranks for: Ulcerative Colitis |  ileal pouch |  anal anastomosis |  dysplasia cancer |  oncologic outcome
    KOL Index score: 11864

    PURPOSE: This study was designed to evaluate the pregnancies, method of delivery, and functional results of females with chronic ulcerative colitis who have an ileal pouch-anal anastomosis.

    METHODS: A mailed questionnaire was sent to all females with an ileal pouch-anal anastomosis for chronic ulcerative colitis. Information on the pregnancy, method of delivery, and outcome was collected. Those females who had a successful pregnancy and delivery were contacted by telephone to clarify ...

    Also Ranks for: Pouch Function |  ulcerative colitis |  pregnancy delivery |  anal anastomosis |  females ileal
    KOL Index score: 11685

    OBJECTIVE: Previous investigations of short-term outcomes after preoperative exposure to biological therapy in inflammatory bowel disease (IBD) were conflicting. The authors aimed to assess postoperative outcomes in patients who underwent abdominal surgery with recent exposure to anti-tumour necrosis factor therapy.

    DESIGN: A retrospective case-control study with detailed matching was performed for subjects with IBD with and without exposure to biologics within 180 days of abdominal ...

    Also Ranks for: Abdominal Surgery |  biological therapy |  inflammatory bowel disease |  monoclonal antibodies |  postoperative outcomes
    KOL Index score: 11552

    PURPOSE: This study was designed to assess the effect of ileal pouch-anal anastomosis on sexual function and quality of life in men and women.

    METHODS: Sexual function of patients undergoing ileal pouch-anal anastomosis from February 2005 to June 2006 was prospectively evaluated using the International Index of Erectile Function in men and Female Sexual Function Index in women. Quality of life was assessed using the Short Inflammatory Bowel Disease Questionnaire. Preoperative scores were ...

    Also Ranks for: Sexual Function |  anal anastomosis |  quality life |  ulcerative colonic pouches |  months surgery
    KOL Index score: 11275

    OBJECTIVE: To measure sexual function and quality of life (QOL) after rectal cancer treatment.

    SUMMARY BACKGROUND DATA: Previous studies on sexual function after rectal cancer treatment have focused on males and have not used validated instruments.

    METHODS: Patients undergoing curative rectal cancer surgery from 1980 to 2003 were administered a questionnaire, including the Female Sexual Function Index (FSFI) or International Index of Erectile Function (IIEF), and the EORTC QLQ-C30/CR-38. ...

    Also Ranks for: Rectal Cancer |  female sexual |  psychological surveys |  surgical procedure |  erectile function
    KOL Index score: 11233

    BACKGROUND: Colorectal cancer (CRC) is a major cause of morbidity and mortality in industrialized countries. Experimental evidence has supported the hypothesis that dietary fibre may be protective for the development of CRC, although epidemiologic data have been inconclusive.

    OBJECTIVES: We have conducted a systematic review and meta-analysis to assess the effect of dietary fibre on the incidence or recurrence of colorectal adenomas, the incidence of CRC, and the development of adverse ...

    Also Ranks for: Dietary Fibre |  colorectal adenomas |  adenomatous polyps |  incidence recurrence |  randomized controlled
    KOL Index score: 11181

    BackgroundMagnetic resonance imaging (MRI) is increasingly being used for rectal cancer staging. The purpose of this study was to determine the accuracy of phased array MRI for T category (T1–2 vs. T3–4), lymph node metastases, and circumferential resection margin (CRM) involvement in primary rectal cancer.MethodsMedline, Embase, and Cochrane databases were searched using combinations of keywords relating to rectal cancer and MRI. Reference lists of included articles were also searched ...

    Also Ranks for: Rectal Cancer |  lymph node |  mri category |  resection margin |  diagnostic odds ratio


    Robin Susan McLeod: Influence Statistics

    Sample of concepts for which Robin Susan McLeod is among the top experts in the world.
    Concept World rank
    cjp differences #1
    cumulative nsaid dose #1
    rbct gastrointestinal surgery #1
    funding new techniques #1
    evidence clinical acumen #1
    optimisation preoperative assessment #1
    mcc frequency #1
    female humans lni #1
    361 pathologists #1
    moderated journal club #1
    57 unique hospitals #1
    treatment option risk #1
    jreservoir #1
    internal sphincterotomy treatment #1
    mri tcategory #1
    cutaneous fistulae #1
    pouchitis reservoir #1
    33238 patients #1
    delivery pouch #1
    topical nitroglycerin #1
    instances surgery #1
    clinical expertise evidence #1
    clinical questions respect #1
    completeness ors #1
    fact operations #1
    referrals elus #1
    listserve discussion #1
    stool phylogenetic gap #1
    stapled iaa #1
    desmoids mesentery #1
    gastrointestinal hormone profile #1
    study sexual problems #1
    ebrs journal clubs #1
    gdg systematic reviews #1
    detection rates pathologists #1
    process evaluation champions #1
    canada magnetic resonance #1
    community hospitals mccs #1
    enablers enhanced recovery #1
    iaa ileostomy #1
    journal club format #1
    nitroglycerin fecal incontinence #1
    cost lowdose heparin #1
    nominal workshop #1
    users tcategory #1
    rectal cancer 40 #1
    effectiveness enhanced recovery #1
    synoptic mri #1
    jpouch spouch #1
    noncounselling patients #1

    Key People For Ulcerative Colitis

    Top KOLs in the world
    William J Sandborn∥
    ulcerative colitis inflammatory bowel disease certolizumab pegol
    JeanFr’ed’eric JeanFrederic
    ulcerative colitis inflammatory bowel disease ibd patients
    Stephen B Hanauer
    ulcerative colitis inflammatory bowel disease certolizumab pegol
    Rutgeerts RUTGEERTS
    ulcerative colitis crohns disease mucosal healing
    Severine ARA VERMEIRE
    ulcerative colitis inflammatory bowel disease mucosal healing
    Schreiber Schreiber
    ulcerative colitis inflammatory bowel disease certolizumab pegol

    Robin Susan McLeod:Expert Impact

    Concepts for whichRobin Susan McLeodhas direct influence:Ulcerative colitis,  Rectal cancer,  Colorectal cancer,  Enhanced recovery,  Ileorectal anastomosis,  Inflammatory bowel disease,  Ileal pouch,  Familial adenomatous polyposis.

    Robin Susan McLeod:KOL impact

    Concepts related to the work of other authors for whichfor which Robin Susan McLeod has influence:Ulcerative colitis,  Rectal cancer,  Inflammatory bowel disease,  Enhanced recovery,  Restorative proctocolectomy,  Ileal pouch,  Postoperative complications.



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    From the Department of Surgery, Temerty Faculty of Medicine, University of Toronto, Toronto, Ont. | Department of Surgery, University of Toronto, Toronto, Ontario, Canada | Université Laval, Quebec, QC, Canada | Ontario Health (Cancer Care Ontario),