• Disease
  • Erythema
  • Erythema Nodosum
  • Luis Requena

    Prominent publications by Luis Requena

    KOL Index score: 17195

    BACKGROUND: Erythema induratum of Bazin is a mostly lobular panniculitis. There is considerable controversy in the literature about whether or not vasculitis is a histopathologic requirement to establish the diagnosis of erythema induratum of Bazin. Even accepting vasculitis as a histopathologic criterion, there is no agreement about the nature and size of the involved vessels.

    OBJECTIVE: The main goal of our study was to investigate whether or not vasculitis was present in a large ...

    Also Ranks for: Erythema Induratum |  lobular panniculitis |  small vessels |  connective tissue |  histopathologic diagnosis
    KOL Index score: 13509

    BACKGROUND: Myoepithelial neoplasms, both benign and malignant, are rare but well-established clinicopathologic entities in the salivary glands, the breast, and the lung. Despite similarities between cutaneous sweat glands and glandular structures in the above-mentioned organs as well as the presence of regular myoepithelial cells around cutaneous eccrine/apocrine glands, the concept of cutaneous myoepithelial neoplasms is still debatable and not commonly accepted.

    METHODS: Twenty ...

    Also Ranks for: Myoepithelial Neoplasms |  cutaneous myoepithelioma |  mixed tumor |  20 cases |  head neck region
    KOL Index score: 11943

    Pigmented mammary Paget disease is a rare clinicopathologic variant of mammary Paget disease. It has been described in female and male patients with intraductal mammary carcinoma extending to the epidermis of the nipple and areola through a lactiferous duct. Pigmented cutaneous metastases from breast carcinoma are uncommon variants of epidermotropic metastatic breast carcinoma. All these lesions may mimic malignant melanoma clinically and histopathologically. From a histopathologic point ...

    Also Ranks for: Breast Carcinoma |  pigmented mammary |  paget disease |  neoplastic cells |  epidermotropic metastases
    KOL Index score: 11601

    BACKGROUND: Imiquimod is an immune response modifier that acts through toll-like receptor 7 to induce cytokine production and a subsequent innate and adaptive cell-mediated immune response. Clinical studies have demonstrated clinical and histological clearance of superficial basal cell carcinoma (sBCC) after treatment with imiquimod 5% cream.

    OBJECTIVES: To evaluate the safety and clinical efficacy of imiquimod (Aldaratrade mark; 3M Pharmaceuticals, St Paul, MN, U.S.A.) 5% cream for the ...

    Also Ranks for: Cell Carcinoma |  imiquimod 5 |  histological clearance |  6 weeks |  vehicle cream
    KOL Index score: 11006

    This second part of our review about vascular proliferations summarizes the clinicopathologic features of the cutaneous vascular hyperplasias and benign neoplasms. Hyperplasias comprise a heterogeneous group of vascular proliferations that eventually show a tendency to regression. Angiolymphoid hyperplasia with eosinophilia is included within the group of hyperplasias because of its historical denomination and its reactive nature, probably as a consequence of an arteriovenous shunt, ...

    Also Ranks for: Vascular Proliferations |  capillary hemangioma |  eosinophilia angiomatosis |  differential endothelium |  angiolymphoid hyperplasia
    KOL Index score: 10833

    BACKGROUND: Wilms tumor 1 (WT1) protein is expressed during angiogenesis and malignant transformation of endothelial cells and can be helpful to distinguish between proliferative and malformative vascular lesions.

    METHODS: We evaluated retrospectively 117 vascular neoplasms and 50 vascular malformations. Vascular neoplasms included infantile hemangioma (n = 87), noninvoluting congenital hemangioma (n = 5), rapidly involuting congenital hemangioma (n = 3), tufted angioma (n = 8), pyogenic ...

    Also Ranks for: Vascular Malformations |  tumor 1 |  infantile hemangioma |  positive expression |  endothelial cells
    KOL Index score: 10783

    BACKGROUND: Chilblains ('COVID toes') are being seen with increasing frequency in children and young adults during the COVID-19 pandemic. Detailed histopathological descriptions of COVID-19 chilblains have not been reported, and causality of SARS-CoV-2 has not yet been established.

    OBJECTIVES: To describe the histopathological features of COVID-19 chilblains and to explore the presence of SARS-CoV-2 in the tissue.

    METHODS: We examined skin biopsies from seven paediatric patients ...

    Also Ranks for: Covid19 Chilblains |  endothelial cells |  electron microscopy |  skin biopsies |  histopathological features
    KOL Index score: 10617

    The panniculitides represent a group of heterogeneous inflammatory diseases that involve the subcutaneous fat. The specific diagnosis of these diseases requires histopathologic study because different panniculitides usually show the same clinical appearance, which consists of subcutaneous erythematous nodules on the lower extremities. However, the histopathologic study of panniculitis is difficult because of an inadequate clinicopathologic correlation, and the changing evolutionary ...

    Also Ranks for: Septal Panniculitis |  subcutaneous fat |  needle diagnosis |  nodosum humans |  histopathologic study
    KOL Index score: 10566

    Desmoplastic melanoma (DM) is a rare variant of spindle cell melanoma, which usually develops in sun-damaged skin of elderly patients. Often the lesion is nonpigmented and frequently mistaken for a nonmelanocytic proliferation, which delays diagnosis and treatment and therefore worsens the prognosis. The spindle shape of neoplastic melanocytes, the prominent desmoplasia, and the frequent neurotropism of neoplastic melanocytes are its most characteristic histopathological features. We ...

    Also Ranks for: Malignant Melanoma |  cases dm |  clinicopathologic analysis |  spindle cells |  breslow thickness
    KOL Index score: 10223

    Several isolated markers have been proposed to aid in differential diagnostic of difficult melanocytic lesions, albeit none has been shown to be definitive in differentiating Spitz nevus from melanoma. This study proposes a wide panel of 22 markers having important functions in different biological functions (cell cycle, apoptosis, DNA repair proteins and membranous receptors) to provide a combination of proteins associated with either benign or malignant phenotype. Using tissue ...

    Also Ranks for: Spitz Nevi |  immunohistochemical profile |  preschool diagnosis |  cyclin d1 |  aged nevus
    KOL Index score: 10211

    Several types of cutaneous vascular proliferations have been described in areas of irradiated skin, including both benign lesions, such as benign lymphangiomatous papules, atypical vascular lesions, or benign lymphangioendothelioma, and malignant neoplasms such as high-grade angiosarcomas. This report describes the clinicopathologic features of 15 cases of different types of benign cutaneous vascular proliferations arisen within irradiated skin. All patients were female ranging in age ...

    Also Ranks for: Vascular Proliferations |  irradiated skin |  endothelial cells |  benign lymphangiomatous papules |  breast carcinoma
    KOL Index score: 10194

    Cutaneous T-cell lymphoma (CTCL) is a heterogeneous group of primary cutaneous T-cell lymphoproliferative processes, mainly composed of mycosis fungoides and Sézary syndrome, the aggressive forms of which lack an effective treatment. The molecular pathogenesis of CTCL is largely unknown, although neoplastic cells show increased signaling from T-cell receptors (TCRs). DNAs from 11 patients with CTCL, both normal and tumoral, were target-enriched and sequenced by massive parallel ...

    Also Ranks for: Plcg1 Mutations |  cell lymphoma |  nuclear factor |  sézary syndrome |  mycosis fungoides
    KOL Index score: 10168

    We report a typical case of papular-purpuric "gloves and socks" syndrome (PPGSS) in which primary infection by parvovirus B19 was demonstrated by seroconversion to this virus; parvovirus B19 DNA was also identified by polymerase chain reaction (PCR) methods in the sera of the patient and in the cutaneous biopsy specimen, both taken 4 days after the onset of clinical manifestations. To our knowledge, this is the fourth published case in which parvovirus B19 DNA has been recovered from the ...

    Also Ranks for: Parvovirus B19 |  cutaneous lesions |  chain reaction |  socks syndrome ppgss |  primary infection


    Luis Requena: Influence Statistics

    Sample of concepts for which Luis Requena is among the top experts in the world.
    Concept World rank
    eosinófilas #1
    necrosis adipocytes panniculitides #1
    fish eh #1
    syphilis secondary #1
    lesions phlda1 #1
    myc camta1 #1
    sebaceous differentiation cases #1
    abrupt thinning #1
    erosive ulcerated dermatofibroma #1
    epithelioid angiomatous #1
    rare histopathologic variants #1
    cutaneous hyperplasias #1
    cutaneous deposits #1
    induratum bazin #1
    nucléolos prominentes #1
    hypopigmented macules imatinib #1
    nodosum erythema #1
    generalized livedo #1
    brealey miller #1
    papules vesicles #1
    histopathologic variant #1
    hemangiomas neoplasms #1
    horn trichilemmal #1
    altered stroma #1
    small ductal structures #1
    panniculitis sites #1
    cases lichenoid #1
    lesion dermalsubcutaneous interface #1
    vasculitis panniculitis #1
    bazin histopathologic #1
    dermis severe #1
    microcystic adnexal adenoma #1
    lower limb lipoatrophy #1
    squamotization #1
    extensor surfaces #1
    rare benign process #1
    aging acrylates #1
    cutaneous mixed #1
    nasal comedones #1
    hemosiderótico #1
    aeb903 cytokeratins #1
    49yearoldwoman #1
    vascular proliferations #1
    neoplastic aggregations case #1
    melanocytes hypopigmented lesions #1
    benign neoplasms #1
    defined vessels #1
    clinical histopathologic #1
    reed nevus #1

    Key People For Erythema Nodosum

    Top KOLs in the world
    Luis Requena
    erythema nodosum neoplastic cells skin neoplasms
    Edouard M Grosshans
    lupus erythematosus langerhans cells cutaneous metastasis
    Bernard J Cribier
    basal cell chronic urticaria skin neoplasms
    Ernest Heid
    cutaneous metastasis schnitzler syndrome erythema nodosum
    Anne Caille
    erythema nodosum 129 cases streptococcal infections
    Evaristo Sánchez Yus
    sebaceous differentiation erythema nodosum intradermal nevus

    Luis Requena:Expert Impact

    Concepts for whichLuis Requenahas direct influence:Erythema nodosum,  Vascular neoplasms,  Neoplastic cells,  Skin neoplasms,  Histopathologic findings,  Basal cell carcinoma,  Differential diagnosis,  Histopathologic study.

    Luis Requena:KOL impact

    Concepts related to the work of other authors for whichfor which Luis Requena has influence:Basal cell carcinoma,  Skin neoplasms,  Differential diagnosis,  Erythema nodosum,  Mycosis fungoides,  Cutaneous metastases,  Nevus sebaceus.



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    Servicio de Dermatología, Fundación Jiménez Díaz, Madrid, Spain. | Department of Dermatology, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain | Dermatology Department, Hospital Fundación Jiménez Díaz, Madrid, Spain. | Department of Derma