• Esophageal Achalasia
    • Yasutoshi Kobayashi
    • Yasutoshi Kobayashi: Influence Statistics

      Yasutoshi Kobayashi

      Yasutoshi Kobayashi

      Department of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, Japan | Department of Medicine, Division of Gastroenterology, Jichi Medical ...

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      Yasutoshi Kobayashi:Expert Impact

      Concepts for whichYasutoshi Kobayashihas direct influence:Esophageal achalasia,Gastric mucosa,Peroral endoscopic myotomy,Functional dyspepsia,Gastroesophageal reflux disease,Proton pump,Pinstripe pattern,Pylori eradication.

      Yasutoshi Kobayashi:KOL impact

      Concepts related to the work of other authors for whichfor which Yasutoshi Kobayashi has influence:Peroral endoscopic myotomy,Esophageal achalasia,Endoscopic submucosal dissection,Poem patients,Pneumatic dilation.

      KOL Resume for Yasutoshi Kobayashi


      Department of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, Japan


      Division of Gastroenterology, Department of Medicine, Jichi Medical University, Shimotsuke, Japan


      Japan Gastroenterological Endoscopy Society, Tokyo, Japan


      Division of Gastroenterology, Department of Medicine, Jichi Medical University, Shimotsuke, Tochigi 329-0498, Japan


      Kobayashi Internal Medicine Clinic, Kobe, Japan


      Digestive Disease Center, Showa University, Northern Yokohama Hospital, Yokohama, Japan


      Digestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, Japan

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      Sample of concepts for which Yasutoshi Kobayashi is among the top experts in the world.
      Concept World rank
      psp child child #3
      new endoscopic indicator #3
      eradication treat #3
      1 esophageal dilatation #3
      eradication ppibased regimen #3
      pcab based regimen #3
      patients pcabbased regimen #3
      psp abnormal contraction #3
      pyrroles sulfonamides treatment #3
      “pinstripe pattern #3
      achalasia psp #3
      psp achalasia #3
      ppibased regimen 96 #3
      4 functional stenosis #3
      ppibased regimens 95 #3
      5 abnormal contraction #3
      60 nonachalasia subjects #3
      pinstripe pattern psp #3
      pcabbased regimen #3
      pylori pcab #3
      regimen superiority #3
      vpz ppibased regimens #3
      2 regimens 95 #3
      3 whitish #4
      higher rate eradication #4
      171558 #4
      vpzbased regimen #4
      statements finalize #4
      tokyo establish #4
      finalize recommendations #4
      gerd symptoms year #6
      vonoprazan sustained resolution #6
      vonoprazan gastrointestinal #6
      vonoprazan year #6
      erosive esophagitis vonoprazan #6
      ppibased regimen #6
      patients postprandial distress #6
      myotomy location #7
      vpz proton #7
      scores eckardt #7
      superiority vpz #7
      scores pressures #7
      2 abnormal retention #7
      humans combination endoscopy #7
      nonadjusted iptwadjusted #8
      myotomy completed #8
      iptwadjusted bloc resection #8
      pcm bloc resection #8
      achalasia child child #8
      iptwadjusted pcm #8
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      Prominent publications by Yasutoshi Kobayashi

      KOL-Index: 11791

      BACKGROUND AND AIM: Safety and effectiveness of cold snare polypectomy (CSP) compared with hot snare polypectomy (HSP) has been reported. The aim of the present study is to carry out a meta-analysis of the efficacy and safety of HSP and CSP.

      METHODS: Randomized controlled trials were reviewed to compare HSP with CSP for resecting small colorectal polyps. Outcomes reviewed include complete resection rate, polyp retrieval, delayed bleeding, perforation and procedure time. Outcomes were ...

      Known for Hsp Csp | Colorectal Polyps | Snare Polypectomy | Delayed Bleeding | Complete Resection Rate
      KOL-Index: 10614

      BACKGROUND AND AIM: Linked color imaging (LCI) is a novel image-enhancing technology which enhances color differences between a colorectal lesion and surrounding mucosa with enough brightness to illuminate the wide colorectal lumen. The aim of this study is to compare colorectal polyp detection using LCI with that using white light imaging (WLI).

      METHODS: Randomized controlled trials and prospective studies comparing LCI with WLI for colorectal polyp detection were selected. Outcomes ...

      Known for Linked Color Imaging | Lci Wli | Polyp Detection | White Light | Color Colorectal
      KOL-Index: 10071

      BACKGROUND: Recent technological advances have allowed superficially spreading intramucosal carcinomas of the esophagus to be successfully resected by circumferential endoscopic submucosal dissection (cESD). After this procedure, esophageal strictures develop in most patients and are mainly treated by endoscopic balloon dilation (EBD).

      OBJECTIVE: To compare oral steroids plus EBD with EBD alone for the management of benign esophageal strictures after cESD.

      DESIGN: Retrospective cohort ...

      Known for Balloon Dilation | Oral Steroid | Esophageal Carcinoma | Ebd Sessions | Endoscopic Submucosal
      KOL-Index: 9421

      BACKGROUND AND STUDY AIMS: Intrapapillary capillary loops (IPCLs) have been used to estimate histopathological atypia and the invasion depth of squamous cell carcinoma (SCC). The aim of this study was to evaluate the clinical significance of IPCLs.

      PATIENTS AND METHODS: A total of 358 consecutive patients with esophageal neoplasia on magnifying narrow-band imaging (M-NBI) were studied. The lesions were categorized according to the IPCL classification of Inoue et al. and were subsequently ...

      Known for Intrapapillary Capillary Loops | Squamous Cell | Sensitivity Specificity | Invasion Depth | Narrowband Imaging
      KOL-Index: 9151

      Gastroesophageal reflux disease (GERD) is commonly treated by primary care physicians. Although proton pump inhibitors (PPI) have been the mainstay of GERD treatment for two decades, in some patients GERD is refractory to standard dose PPI for more than eight weeks and is referred to as PPI-resistant GERD. Vonoprazan, a novel competitive acid blocker, became available in Japan for the treatment of patients with GERD, and has greater acid inhibition than existing PPIs. The aim of the ...

      Known for Patients Gerd | Gastroesophageal Reflux Disease | Vonoprazan Treatment | Ppi Resistant | Pump Inhibitor
      KOL-Index: 8574

      BACKGROUND: After the first case of per-oral endoscopic myotomy (POEM) at our institution in 2008, the procedure was quickly accepted as an alternative to surgical myotomy and is now established as an excellent treatment option for achalasia. This study aimed to examine the safety and outcomes of POEM at our institution.

      STUDY DESIGN: Per-oral endoscopic myotomy was performed on 500 consecutive achalasia patients at our institution between September 2008 and November 2013. A review of ...

      Known for Oral Endoscopic Myotomy | Esophageal Sphincter | Child Child | 2 Months | Lower Esophagoscopy
      KOL-Index: 8415

      BACKGROUND: Peroral endoscopic myotomy (POEM) was developed by our group to provide a less invasive permanent treatment for esophageal achalasia.

      PATIENTS AND METHODS: POEM was performed in 17 consecutive patients with achalasia (10 men, 7 women; mean age 41.4 years). A long submucosal tunnel was created (mean length 12.4 cm), followed by endoscopic myotomy of circular muscle bundles of a mean total length of 8.1 cm (6.1 cm in distal esophagus and 2.0 cm in cardia). Smooth passage of an ...

      Known for Esophageal Achalasia | Endoscopic Myotomy | Reflux Esophagitis | Distal Esophagus | Angeles Classification
      KOL-Index: 7994

      BACKGROUND: A novel potassium-competitive acid blocker, vonoprazan (VPZ), improves first-line Helicobacter pylori eradication success. The aim of this systematic review is to clarify the effectiveness and safety of second-line H. pylori eradication therapy comparing VPZ and proton pump inhibitor (PPI)-based regimens.

      METHODS: Medline (PubMed), EMBASE, Web of Science, Cochrane Library, and the Japan Medical Abstract Society Database were searched.

      RESULTS: We selected 16 studies for ...

      Known for Helicobacter Pylori | Eradication Therapy | Proton Pump | Vonoprazan Vpz | Cochrane Library
      KOL-Index: 7750

      BACKGROUND AND AIMS: Colonic endoscopic submucosal dissection (ESD) is more difficult than rectal ESD because of poor maneuverability of the endoscope due to physiologic flexion, peristalsis, and respiratory movements. The aim of this study was to assess the usefulness of the pocket-creation method (PCM) for colonic ESD compared with the conventional method (CM) regardless of lesion shape or location.

      METHODS: A total of 887 colorectal lesions were treated by ESD. Of 887 lesions, 271 ...

      Known for Colonic Endoscopic | Esd Pcm | Bloc Resection | Creation Method | Dissection Speed
      KOL-Index: 7535

      BACKGROUND: The endoscopic pressure study integrated system (EPSIS) is a prototypic system for monitoring intragastric pressure (IGP) fluctuations that result from opening of the cardia during gastric distension. The performance of EPSIS for the diagnosis of gastroesophageal reflux disease (GERD) was evaluated.

      METHODS: A retrospective analysis was conducted of data prospectively collected over a 2-year period from 59 patients who underwent gastroscopy, EPSIS, and 24-hour pH monitoring. ...

      Known for Gastroesophageal Reflux Disease | Diagnostic Tool | Epsis Gerd | Pressure Study | Flat Pattern
      KOL-Index: 7221

      OBJECTIVE: The novel potassium-competitive acid blocker, vonoprazan, provides rapid and effective acid suppression. The aim of this study is to evaluate the long-term outcomes of patients with symptomatic gastroesophageal reflux disease (GERD) treated with vonoprazan.

      METHODS: This retrospective cohort study included 55 patients with symptomatic GERD treated with vonoprazan who have been followed for more than one year. The effectiveness of vonoprazan on gastrointestinal symptoms was ...

      Known for Gerd Symptoms | Gastroesophageal Reflux | Erosive Esophagitis | Longterm Outcomes | Postprandial Distress
      KOL-Index: 6510

      BACKGROUND AND STUDY AIMS: Endocytoscopy enables observation at 450-fold magnification during gastrointestinal endoscopy, allowing on-site "optical biopsy." We compared the accuracies of endocytoscopy and standard biopsy for the diagnosis of colorectal neoplasms.

      PATIENTS AND METHODS: We performed a randomized, controlled, open-label trial of patients with colorectal lesions (≥ 5 mm) detected during colonoscopy in a tertiary referral center. We randomly assigned the 203 detected lesions ...

      Known for Colorectal Neoplasms | Neoplastic Lesions | Gastrointestinal Endoscopy | 5 Mm | Endocytoscopic Findings
      KOL-Index: 6426

      AIM: We conducted a meta-analysis to compare the diagnostic test performance of chromoendoscopy and narrow band imaging (NBI) for colonic neoplasms.

      METHOD: MEDLINE, EMBASE and the Cochrane Library were searched (1966 to March 2009). Articles were included if: (i) chromoendoscopy or NBI was used, (ii) sensitivity and specificity were reported; (iii) absolute numbers of true-positive, false-positive, true-negative and false-negative results were provided or could be calculated; and (iv) ...

      Known for Band Imaging | Diagnostic Performance | Sensitivity Specificity | Colonic Neoplasms | Cochrane Library
      KOL-Index: 6152

      Peroral endoscopic myotomy (POEM) is a novel clinical technique developed in Japan used to treat esophageal achalasia and esophageal motility disorders. This technique has been rapidly accepted and widely disseminated throughout our clinical practice because of its low invasiveness, technical novelty, and high efficacy. Since the advent of POEM, there have been no clinical guidelines that clearly indicated its standard of care, and these guidelines have been anticipated both nationally ...

      Known for Endoscopic Myotomy | Esophageal Achalasia | Clinical Questions | Retrospective Studies | Practice Guidelines
      KOL-Index: 6089

      BACKGROUND AND STUDY AIMS: Endoscopic diagnosis of esophageal achalasia lacking typical endoscopic features can be extremely difficult. The aim of this study was to identify simple and reliable early indicator of esophageal achalasia.

      PATIENTS AND METHODS: This single-center retrospective study included 56 cases of esophageal achalasia without previous treatment. As a control, 60 non-achalasia subjects including reflux esophagitis and superficial esophageal cancer were also included in ...

      Known for Esophageal Achalasia | Pinstripe Pattern | Endoscopic Findings | Previous Treatment | Esophagogastric Junction

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      Department of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, Japan | Department of Medicine, Division of Gastroenterology, Jichi Medical University, Shimotsuke, Japan | Department of Medicine, Division of Gastroenterology,

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