Barry L Smith: Influence Statistics

Barry L Smith

Barry L Smith

AgResearch, Ruakura Agricultural Research Centre, Private Bag 3123, Hamilton, New Zealand | AgResearch, Ruakura Agricultural Research Centre, Private Bag 3123, Hamilton 2001, ...

Barry L Smith: Expert Impact

Concepts for which Barry L Smith has direct influence: New zealand , Facial eczema , Bracken fern , Ryegrass staggers , Body temperature , Butylated hydroxyanisole , Electromyographic activity .

Barry L Smith: KOL impact

Concepts related to the work of other authors for which for which Barry L Smith has influence: New zealand , Facial eczema , Pteridium aquilinum , Bracken fern , Ergot alkaloids , Urinary bladder , Perennial ryegrass .

KOL Resume for Barry L Smith

Year
2007

AgResearch, Ruakura Agricultural Research Centre, Private Bag 3123, Hamilton, New Zealand

2005

AgResearch, Ruakura Agricultural Research Centre, Private Bag 3123, Hamilton 2001, New Zealand

2003

Food Science Group, AgResearch, Ruakura Research Centre, PB 3123, Hamilton, New Zealand

2002

Toxinology and Food Safety Research Group, AgResearch, Ruakura Research Centre, Hamilton, New Zealand.

2001

Toxinology and Food Safety Research Group, New Zealand Pastoral Agricultural Research Institute, Ruakura Agricultural Research Centre, Private Bag 3123, Hamilton, New Zealand

1999

Toxinology and Food Safety Research Group, New Zealand Pastoral Agriculture Research Institute (Ltd), Hamilton, PB 3123, New Zealand

1998

AgResearch, Ruakura Agricultural Research Centre, East Street, Private Bag 3123, Hamilton, New Zealand

1997

New Zealand Pastoral Agricultural Research Institute Ltd, Ruakura Research Centre, Hamilton, New Zealand

1996

New Zealand Pastoral Agriculture Research Institute, Ruakara Agricultural Research Centre, Hamilton New Zealand

1995

Senior Scientist, AgResearch, New Zealand Pastoral Agriculture Research Institute Ltd., Ruakura Agricultural Centre, East Street, Private Bag 3123, Hamilton, New Zealand

1994

New Zealand Pastoral Agriculture Research Institute, Hamilton, New Zealand

1993

New Zealand Pastoral Agriculture Research Institute (Ltd), Ruakura Agricultural Centre, Private Bag, Hamilton, New Zealand

1992

MAF Technology, Ruakura Agricultural Centre, Private Bag, Hamilton, New Zealand

1991

Ruakura Agricultural Centre, Private Bag, Hamilton, New Zealand.

1989

Ruakura Agricultural Centre, Ministry of Agriculture and Fisheries Private Bag, Hamilton New Zealand

1987

Ruakura Agricultural Research Centre, Ministry of Agriculture and Fisheries, Private Bag, Hamilton, New Zealand

1986

Ruakura Agricultural Research Centre, Private Bag, Hamilton, New Zealand.

Prominent publications by Barry L Smith

KOL-Index: 9886 . AIMS: To study the increase in phylloerythrin concentration in plasma and the disposition of phylloerythrin in skin and other tissues of sheep in which the hepatogenous photosensitisation,facial eczema, had been experimentally induced by dosing with the mycotoxin, sporidesmin. Spectroscopic differences between plasma and skin measurements of animals kept inside and outside after dosing ...
Known for Facial Eczema | Phylloerythrin Plasma | Healthy Sheep | Emission Spectra
KOL-Index: 8581 . Ryegrass staggers is a seasonal mycotoxicosis of grazing livestock characterised by tremors, in coordination and a staggering gait almost unaccompanied by physical lesions. Deaths occur only as a consequence of accident or starvation. Outbreaks, in summer and autumn, occur only on pasture in which endophyte (Neotyphodium lolii)-infected perennial ryegrass (Lolium perenne) predominates and ...
Known for Ryegrass Staggers | Lolium Perenne | Neotyphodium Lolii | Secondary Metabolites
KOL-Index: 8565 . The mycotoxic tremorgens penitrem, paxilline and lolitrem B had profound effects on electromyographic (EMG) activity of smooth muscle of the reticulorumen in conscious sheep, with a similar time course of action to their respective characteristic effects on the induction (1 to 2, 15 to 20 and 20 to 30 minutes) and the duration (1 to 2, 1 to 2 and 8 to 12 hours) of tremoring. Responses to ...
Known for Electromyographic Activity | Tremorgenic Mycotoxins | Smooth Muscle | Penitrem Lolitrem
KOL-Index: 7849 . It has previously been shown that rats pre-treated with butylated hydroxyanisole (BHA), a well-known inducer of the enzyme DT-diaphorase, are protected against the toxic effects of 2-methyl-1,4-naphthoquinone but are made more susceptible to the harmful action of 2-hydroxy-1,4-naphthoquinone. In the present experiments, the effects of BHA have been compared with those of other inducers of ...
Known for Inducers Dtdiaphorase | Naphthoquinone Rats | Enzyme Diaphorase | 2 Hydroxy14
KOL-Index: 7727 . The electromyographic (EMG) activity of skeletal muscle was investigated as a method of recording the tremorgenic activity of the mycotoxins penitrem, paxilline and lolitrem B in sheep. EMG recordings were made concurrently from the abomasal antrum and duodenum to study the effects of these tremorgens on smooth muscle of the gut. Penitrem (2.2 to 7.5 micrograms kg-1) induced mild to ...
Known for Smooth Muscle | Electromyographic Activity | Paxilline Lolitrem | Inhibitory Effects
KOL-Index: 7563 . The enzyme DT-diaphorase catalyses the 2-electron reduction of quinones. This reaction may facilitate the detoxification of such compounds, since the hydroquinone so formed can be converted into non-toxic conjugates. There is evidence for the involvement of DT-diaphorase in the detoxification of menadione (2-methyl-1,4-naphthoquinone) in a wide range of cells and tissues in vitro, but no ...
Known for Butylated Hydroxyanisole | Haemolytic Anaemia | Enzyme Diaphorase | Harmful Effects
KOL-Index: 6735 . OBJECTIVE: To compare the effects of the ergot alkaloid ergovaline with effects of ergotamine on blood pressure, heart rate, respiratory rate, and body temperature in conscious sheep. ANIMALS: 3 sheep with indwelling arterial catheters. PROCEDURE: Ergotamine and ergovaline were injected IV (20 nmol/kg), and their effects on arterial blood pressure, heart rate, respiratory rate and pattern, ...
Known for Effects Ergotamine | Heart Rate | Sheep Ergovaline | Blood Pressure
KOL-Index: 6568 . It has previously been shown that rats pre-treated with butylated hydroxyanisole (BHA), a well-known inducer of the enzyme DT-diaphorase, are protected against the harmful effects of 2-methyl-1,4-naphthoquinone. This is consistent with a role for diaphorase in the detoxification of this quinone, but it is not known if increased tissue levels of this enzyme give protection against other ...
Known for Butylated Hydroxyanisole | Rats Bha | Enzyme Diaphorase | Quinone Naphthoquinones
KOL-Index: 6404 . OBJECTIVE: To investigate the effects of IV administration of ergotamine and ergovaline and intraruminal administration of ergotamine on electromyographic (EMG) activity of reticuloruminal smooth muscle in conscious sheep. ANIMALS: 3 sheep with indwelling electrodes in the musculature of the reticulum and rumen. PROCEDURE: In a crossover design study, reticuloruminal motility before and ...
Known for Smooth Muscle | Rumen Sheep | Effects Ergotamine | Vasoconstrictor Agents
KOL-Index: 5766 . Facial eczema (pithomycotoxicosis), a photosensitisation of ruminants grazing pasture, has been known in New Zealand for over 100 years, but its cause, a toxin produced by a largely saprophytic fungus, Pithomyces chartarum, growing on litter at the base of pasture and sporing profusely under warm moist conditions in late summer and autumn, was found only 50 years ago. As the fungus spores ...
Known for Facial Eczema | New Zealand | Toxin Sporidesmin | Pithomyces Chartarum
KOL-Index: 5698 . Bracken fern (Pteridium esculentum) was harvested from two sites LB and TB one of which (TB) was on a central North Island New Zealand farm where bovine enzootic haematuria (BEH) was known to occur. The fern was dried, ground and incorporated (25% w/w) into a pelleted diet and fed to female rats for a total of 162 days. Fifteen weeks later when the rats were autopsied it was found that ...
Known for New Zealand | Pteridium Esculentum | Bracken Fern | Bovine Enzootic Haematuria
KOL-Index: 5545 . Mycotoxicoses are some of the most important diseases of animals grazing pastures in New Zealand, especially in northern areas where the disease, facial eczema, occurs. New Zealand scientists have led the world in research on facial eczema and endophyte-related diseases associated with tremoring. Facial eczema (pithomycotoxicosis) was one of the first mycotoxicoses to be studied ...
Known for New Zealand | Grazing Animals | Facial Eczema | Fusarium Spp
KOL-Index: 5330 . Bracken fern (Pteridium spp.) causes cancer of the oesophagus and the urinary bladder in cattle and sheep. Ptaquiloside (PT) is believed to be the carcinogenic principle which alkylates DNA when activated to its unstable dienone form (APT) under alkaline conditions. In this report we present evidence for the presence of PT-DNA adducts in the ileum of bracken fem-fed calves using the ...
Known for Bracken Fern Carcinogenesis | Urinary Bladder | Dna Alkylation | Alkaline Conditions

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AgResearch, Ruakura Agricultural Research Centre, Private Bag 3123, Hamilton, New Zealand | AgResearch, Ruakura Agricultural Research Centre, Private Bag 3123, Hamilton 2001, New Zealand | Toxicology, AgResearch, Ruakura Research Centre, Hamilton, Ne