GEORGES J Klein: Influence Statistics

GEORGES J Klein

GEORGES J Klein

London Heart Rhythm Program, University Hospital, Western University, London, Ontario, Canada. | London Heart Rhythm Program, Western University, London, Ontario, Canada. | ...

GEORGES J Klein: Expert Impact

Concepts for which GEORGES J Klein has direct influence: Atrial fibrillation , Accessory pathway , Ventricular tachycardia , Ventricular fibrillation , Catheter ablation , Accessory pathways , White syndrome .

GEORGES J Klein: KOL impact

Concepts related to the work of other authors for which for which GEORGES J Klein has influence: Atrial fibrillation , Catheter ablation , Heart failure , Ventricular tachycardia , Sudden cardiac death , Sinus rhythm , Accessory pathway .

KOL Resume for GEORGES J Klein

Year
2022

London Heart Rhythm Program, University Hospital, Western University, London, Ontario, Canada.

2020

London Heart Rhythm Program, Western University, London, Ontario, Canada.

2019

Professor of Medicine, Western University, London, Ontario, Canada

2018

University of Western Ontario, Schulich School of Medicine, London, Ontario, Canada

2017

Western University Arrhythmia Service, University Hospital London Canada

2016

Arrhythmia Service, University Hospital, Western University, London, Canada

For the author affiliations, please see the Appendix.

2015

Arrhythmia Services, University Hospital, Western University, 339 Windermere Road, London, Ontario N6A 5A5, Canada

Biostatistics,

2014

Division of Cardiology, Department of Medicine, University of Western Ontario, London, ON, Canada N6G 2V4

University of Western, London, ON, Canada

2013

London Health Sciences Centre and Western University, Division of Nephrology, Department of Medicine, The Toronto General Hospital, University Health Network, Departments of, Medical Biophysics, and, Physiology and Pharmacology, Western University, London, Ont., Canada

2012

Division of Cardiology, Western University, 339 Windermere Road, C6-110, London, Ontario N6A 5A5, Canada

2011

Cedars-Sinai Heart Institute, Los Angeles, California

University of Western Ontario, London, ON, Canada

2010

Arrhythmia Service, Division of Cardiology, University of Western Ontario, London

2009

Arrhythmia Service, Division of Cardiology, University of Western Ontario, London, Ontario, Canada

2008

Division of Cardiology, University of Western Ontario, London, Ontario, Canada.

From the Hôpital Cardiologique du Haut-Lévêque, Bordeaux-Pessac, France (P.J., M.H., F.S., P.B., J.C., M.H.); Hôpital Larriboisière, Paris, France (B.C., F.E.); Montreal Heart Institute, Montreal, Canada (L.M., P.K.); Richard M. Ross Heart Hospital, Columbus, Ohio (E.D.); Department of Cardiology, St. Vincent’s Hospital, Sydney, Australia (R.S.); University Hospital, London, Canada (G.K.); and University of Western Australia, Crawley, Western Australia (R.W.).

Arrhythmia Service, University of Western Ontario, University Hospital, London, Ontario, Canada

Hôpital Cardologique du Haut‐Lévêque and the Université Bordeaux II, Bordeaux, France

2007

Division of Cardiology, Department of Medicine, University of Western Ontario, London, Ontario, Canada.

Arrhythmia Service, University of Western Ontario, London Health Sciences Centre, 339 Windermere Road, London, Ontario N6A 5A5, Canada

Hôpital Cardiologique du Haut‐Lévêque, Bordeaux‐Pessac; and University Victor Segalen, Bordeaux 2, France

2006

Division of Cardiology, Department of Medicine, London Health Sciences Centre, London, Ontario, Canada

2005

From the Division of Cardiology (A.D.K., R.Y., L.J.G., A.C.S., B.D.W., G.J.K.), University of Western Ontario, London, and the Division of Cardiology (M.G.), University of Ottawa, Ottawa, Ontario, Canada.

Division of Cardiology and Cardiac Surgery, University of Western Ontario, London, Ontario, Canada

2004

London Health Sciences Center, London, Ontario, Canada

From the Department of Medicine, University of British Columbia, Vancouver (C.R.K.); the Departments of Medicine (S.J.C., S.Y.) and Clinical Epidemiology and Biostatistics (R.S.R., M.G.), McMaster University, Hamilton, Ontario; the Department of Medicine, University of Calgary, Calgary, Alberta (A.M.G.); the Department of Medicine, University of Ottawa, Ottawa, Ontario (A.S.L.T.); the Institut de Cardiologie de Montreal, Montreal, Quebec (M.T.); the Department of Medicine, Queens University,...

Prominent publications by GEORGES J Klein

KOL-Index: 19610 . BACKGROUND: Despite the clinical importance of atrial fibrillation (AF), the development of chronic nonvalvular AF models has been difficult. Animal models of sustained AF have been developed primarily in the short-term setting. Recently, models of chronic ventricular myopathy and fibrillation have been developed after several weeks of continuous rapid ventricular pacing. We hypothesized ...
Known for Sustained Atrial | Chronic Rapid | 6 Weeks | Posterior Atrium
KOL-Index: 18533 . BACKGROUND: Evidence suggests that physiologic pacing (dual-chamber or atrial) may be superior to single-chamber (ventricular) pacing because it is associated with lower risks of atrial fibrillation, stroke, and death. These benefits have not been evaluated in a large, randomized, controlled trial. METHODS: At 32 Canadian centers, patients without chronic atrial fibrillation who were ...
Known for Physiologic Pacing | Atrial Fibrillation Patients | Ventricular Pacemaker | Risk Stroke
KOL-Index: 15399 . OBJECTIVES: A double-blind randomized trial was designed to determine the efficacy of intravenous and oral disopyramide phosphate in preventing neurally mediated syncope induced by a head-up tilt test. BACKGROUND: Neurally mediated syncope is a frequent cause of syncope and may be induced by head-up tilt testing. Recent uncontrolled trials have suggested that disopyramide may be an ...
Known for Neurally Mediated Syncope | Headup Tilt Testing | Head Tilt | Test Positive
KOL-Index: 15202 . OBJECTIVES: This study was performed to evaluate the impact of beta blockers on QT adaptation to heart rate during the exercise and recovery phases of exercise testing in long QT syndrome. BACKGROUND: Long QT syndrome is characterized by familial syncope and sudden death in the context of sudden heart rate changes. QT hysteresis has been proposed as a phenotypic marker of long QT syndrome, ...
Known for Long Qt Syndrome | Qt Hysteresis | Beta Blockers | Heart Rate
KOL-Index: 15157 . BACKGROUND: Patients with recurrent syncope frequently undergo extensive investigations that consume significant health care resources. Recent advances in long-term monitoring techniques have enhanced diagnostic yield in patients with infrequent symptoms. There is little information on the relative cost-effective profile of the investigative tools used in patients with syncope. METHODS: ...
Known for Patients Syncope | Diagnostic Yield | Cost Diagnosis | Loop Recorder
KOL-Index: 14779 . BACKGROUND: The initial management of syncope or presyncope typically involves short-term cardiac monitoring using a Holter monitor. A loop recorder is used to extend the period of monitoring to increase the probability of obtaining a symptom-rhythm correlation. Loop recorders and Holter monitors are both used commonly, but their utility has not been compared prospectively. METHODS: ...
Known for Loop Recorder | Holter Monitor | Patients Syncope | Ambulatory Female Humans
KOL-Index: 13906 . PURPOSE: Inappropriate administration of intravenous verapamil to patients with wide QRS complex tachycardia due to ventricular tachycardia or atrial fibrillation with Wolff-Parkinson-White syndrome occurs frequently because of misdiagnosis, and may precipitate a cardiac arrest. We evaluated the safety and the diagnostic and therapeutic utility of adenosine triphosphate administered to a ...
Known for Adenosine Triphosphate | Wide Qrs | Complex Tachycardia | Therapeutic Efficacy
KOL-Index: 13782 . BACKGROUND: Atrial fibrillation remains a frequent complication after heart surgery. The optimal strategy to treat the condition has not been established. Several retrospective studies have suggested that a primary rate-control strategy may be equivalent to a strategy that restores sinus rhythm. METHODS: Fifty patients with atrial fibrillation after heart surgery were randomly assigned to ...
Known for Sinus Rhythm | Atrial Fibrillation | Conversion Strategy | Rate Control
KOL-Index: 13665 . BACKGROUND: Shortening of the anterograde effective refractory period (ERP) of the fast pathway has been reported after radiofrequency ablation of the slow pathway. We hypothesized that ERP shortening may be related to autonomic changes, possibly catecholamine release, as a result of ablation. METHODS AND RESULTS: To test this, 10 consecutive patients with atrioventricular node reentry ...
Known for Autonomic Blockade | Fast Pathway | Ablation Slow | Patients Atrioventricular
KOL-Index: 13411 . Invasive electrophysiologic testing and noninvasive testing were compared as methods for identifying patients with Wolff-Parkinson-White syndrome at risk for sudden death. Sixty-seven patients were studied, including nine with a history of ventricular fibrillation. Electrophysiologic testing, using the shortest interval between consecutive pre-excited beats (shortest RR interval) less than ...
Known for Sudden Death | Noninvasive Testing | White Syndrome | Shortest Interval
KOL-Index: 13401 . BACKGROUND: The clinical diagnosis of long-QT syndrome (LQTS) remains challenging when ECG abnormalities are borderline or intermittent. Despite issues with access, cost, and heterogeneity of LQTS mutations, genetic testing remains the diagnostic gold standard for diagnosis of LQTS. We sought to develop a provocative testing strategy to unmask the LQTS phenotype and relate this to the ...
Known for Qt Syndrome | Treadmill Testing | Potassium Channel | Voltagegated Predictive
KOL-Index: 13284 . Radiofrequency catheter ablation is an accepted primary therapy for atrioventricular (AV) node reentrant tachycardia (AVNRT). There is concern that slow pathway ablation in patients with a long anterograde fast pathway effective refractory period (ERP) may potentially impair subsequent node conduction. Eighteen patients (14 women; age 53 +/- 20 years) with symptomatic AVNRT, whose fast ...
Known for Fast Pathway | Atrioventricular Node | Patients Avnrt | Refractory Period
KOL-Index: 12805 . BACKGROUND: After its initial diagnosis, atrial fibrillation (AF) may progress from paroxysmal to chronic AF (CAF). The rate of progression and risk factors for progression are not clearly defined. METHODS: The Canadian Registry of Atrial Fibrillation (CARAF) enrolled patients from 6 Canadian cities at the time of their first electrocardiographic diagnosis of AF. Comprehensive clinical and ...
Known for Atrial Fibrillation | Canadian Registry | Progression Caf | Initial Diagnosis
KOL-Index: 12663 . We examined the electrophysiologic effects of verapamil in eight patients with the Wolff-Parkinson-White syndrome. Verapamil shortened the antegrade effective refractory period of the accessory pathway in three patients and abbreviated the shortest cycle length with 1:1 conduction over the accessory pathway in two patients. More significantly, verapamil decreased the shortest RR interval ...
Known for Atrial Fibrillation | Ventricular Response | Verapamil Patients | White Syndrome

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London Heart Rhythm Program, University Hospital, Western University, London, Ontario, Canada. | London Heart Rhythm Program, Western University, London, Ontario, Canada. | Arrhythmia Service, University Hospital, Western University, London Health Sc