Prominent publications by Rachel M Landisch

KOL Index score: 9413

Skeletal muscle contractility and myosin function decline following ovariectomy in mature female mice. In the present study we tested the hypothesis that estradiol replacement can reverse those declines. Four-month-old female C57BL/6 mice (n = 69) were ovariectomized (OVX) or sham operated. Some mice were treated immediately with placebo or 17beta-estradiol (OVX + E(2)) while other mice were treated 30 days postsurgery. Thirty or sixty days postsurgery, soleus muscles were assessed in ...

Known for Female Mice |  Soleus Muscles |  Induced Muscle |  Contractile Function |  Estradiol Ovx
KOL Index score: 8081

The purpose of this study was to determine the extent to which hindlimb muscles of mdx mice adapt to a voluntary endurance type of exercise. mdx and C57BL mice engaged in 8 weeks of wheel running or maintained normal cage activities. Beneficial adaptations that occurred in mdx mice included changes in muscle mass, fiber size, and fiber types based on myosin heavy chain (MHC) isoform expression. These adaptations occurred without increases in fiber central nuclei and embryonic MHC ...

Known for Mdx Mice |  Voluntary Wheel |  Skeletal Muscular Dystrophy |  Dystrophic Muscle |  Inbred C57bl
KOL Index score: 8029

BACKGROUND: Restorative proctocolectomy with IPAA improves quality of life in patients with medically refractory ulcerative colitis. Although bowel obstruction is common, pouch volvulus is rare and described only in case reports. Diagnosis can be challenging, resulting in delayed care and heightened morbidity.

OBJECTIVE: The purpose of this study was to delineate the symptoms and successful management strategies used in patients with IPAA volvulus that result in pouch salvage.


Known for Pouch Volvulus |  Ulcerative Colitis |  Restorative Proctocolectomy |  Patients Ipaa |  Adenomatous Polyposis
KOL Index score: 5518

BACKGROUND: The management of intestinal rotational abnormalities (IRA) in heterotaxy syndrome (HS) remains inconsistent. Because of the high incidence of malrotation in HS, screening of asymptomatic patients is standard of care in some institutions. The Ladd procedure is the treatment for malrotation, and has been reported to have high complication rates in HS patients.

METHODS: We performed a systematic review of publications describing IRA in pediatric HS patients from January 1993 to ...

Known for Ladd Procedure |  Heterotaxy Syndrome |  Asymptomatic Patients |  Rotational Abnormalities |  Intestinal Volvulus
KOL Index score: 4870

PURPOSE: The purpose of this study was to identify factors associated with attaining fecal continence in children with anorectal malformations (ARM).

METHODS: We performed a multi-institutional cohort study of children born with ARM in 2007-2011 who had spinal and sacral imaging. Questions from the Baylor Social Continence Scale were used to assess fecal continence at the age of ≥4 years. Factors present at birth that predicted continence were identified using multivariable logistic ...

Known for Fecal Continence |  Children Arm |  Anorectal Malformations |  Spinal Anomalies |  Lateral Sacral Ratio
KOL Index score: 4752

BACKGROUND: Anastomotic stricture is the most common postoperative complication in infants undergoing repair of esophageal atresia with or without tracheoesophageal fistula (EA/TEF). Stricture indices (SIs) are used to predict infants at risk for stricture requiring dilation. We sought to determine the most accurate SI and optimal timing for predicting anastomotic dilation.

MATERIALS AND METHODS: A retrospective study of infants undergoing repair of EA/TEF between 2008 and 2013 was ...

Known for Atresia Repair |  Anastomotic Stricture |  Logistic Regression Analysis |  Retrospective Studies |  Esophageal Stenosis
KOL Index score: 4506

BACKGROUND: This study evaluates screening practices and the incidence of associated anomalies in infants with anorectal malformations (ARM).

METHODS: We performed a multi-institutional retrospective cohort study of children born between 2007 and 2011 who underwent surgery for ARM at 10 children's hospitals. ARM type was classified based on the location of the distal rectum, and all screening studies were reviewed.

RESULTS: Among 506 patients, the most common ARM subtypes were perineal ...

Known for Anorectal Malformations |  Type Arm |  Perineal Fistula |  Retrospective Studies |  Study Children
KOL Index score: 4049

BACKGROUND/PURPOSE: Elective preterm delivery (EPD) of a fetus with gastroschisis may prevent demise and ameliorate intestinal injury. While the literature on optimal timing of delivery varies, we hypothesize that a potential benefit may be found with EPD.

METHODS: A meta-analysis of publications describing timing of delivery in gastroschisis from 1/1990 to 8/2016 was performed, including studies where either elective preterm delivery (group 1, G1) or preterm gestational age (GA) (group ...

Known for Outcomes Gastroschisis |  Elective Preterm Delivery |  Potential Benefit |  Parenteral Nutrition |  Preterm Gestational Age
KOL Index score: 3926

INTRODUCTION: Isomerism, or heterotaxy syndrome, affects many organ systems anatomically and functionally. Intestinal malrotation is common in patients with isomerism. Despite a low reported risk of volvulus, some physicians perform routine screening and prophylactic Ladd procedures on asymptomatic patients with isomerism who are found to have intestinal malrotation. The primary aim of this study was to determine if isomerism is an independent risk factor for volvulus.

METHODS: Kid's ...

Known for Intestinal Malrotation |  6 Patients |  Heterotaxy Syndrome |  Ladd Procedure |  Level Iii
KOL Index score: 3870

PURPOSE: Comparative outcomes of enhanced percutaneous endoscopic gastrostomy (PEG) and laparoscopic gastrostomy (LG) have not been elucidated in infants. We describe the outcomes and procedural episodic expenditures of PEG versus LG in this high-risk population.

METHODS: One hundred eighty-three gastrostomies in children under 1year were reviewed from our institution spanning 1/2011-6/2015. Pertinent demographics and 3-month complications (mortality, gastrocolic fistula, reoperation, ...

Known for Gastrostomy Peg |  Major Complications |  Retrospective Studies |  Study Level |  Newborn Laparoscopy
KOL Index score: 3712

INTRODUCTION: Venous thromboembolism (VTE) is increasingly prevalent in injured children admitted to the intensive care unit (ICU). Few data exist to support VTE pharmacologic prophylaxis or ultrasound (US) surveillance in children with high bleeding risk. After implementation of screening US guidelines, we sought to describe our experience, hypothesizing that screening US of children at highest risk for VTE results in earlier detection and management.

STUDY DESIGN: A retrospective ...

Known for Venous Thromboembolism |  Risk Vte |  Injured Children |  Pharmacologic Prophylaxis |  Trauma Patients
KOL Index score: 3628

PURPOSE: To report outcomes of sutured and sutureless closure for gastroschisis across a large multi-institutional cohort.

METHODS: A retrospective study of infants with uncomplicated gastroschisis at 11 children's from 2014 to 2016 was performed. Outcomes of sutured and sutureless abdominal wall closure were compared.

RESULTS: Among 315 neonates with uncomplicated gastroschisis, sutured closure was performed in 248 (79%); 212 undergoing sutured closure after silo and 36 undergoing ...

Known for Sutured Closure |  Uncomplicated Gastroschisis |  Pediatric Surgery |  315 Neonates |  Abdominal Wall
KOL Index score: 1023

ObjectiveTo provide generalizable estimates for expected outcomes of simple gastroschisis (SG) and complex gastroschisis (CG) patients from a large multi-institutional cohort for use during counseling.Study designA retrospective study of 394 neonates with gastroschisis at 11 children’s hospitals from January 2013 to March 2017 was performed. Analysis by Fisher’s exact tests and Wilcoxon rank sum tests were performed. Outcomes of complex and simple gastroschisis are reported.ResultThere ...

Known for Complex Gastroschisis
KOL Index score: 1019

BACKGROUND: Perioperative hypothermia decreases nutrient and oxygen delivery to tissues and, in adult studies, increases the risk of infectious complications (ICs). Gastroschisis (GS) places newborns at risk for hypothermia by nature of exposed viscera and excessive heat loss. Although hypothermia is a known cause of mortality in GS, the rate of ICs in this at-risk cohort has not yet been delineated.

MATERIALS AND METHODS: A retrospective cohort study was performed at our single ...

Known for Surgical Site


Rachel M Landisch: Influence Statistics

Sample of concepts for which Rachel M Landisch is among the top experts in the world.
Concept World rank
patients ipaa volvulus #5
ira heterotaxy #5
isomerism intestinal #6
15962403 inpatient admissions #6
low reported risk #6
isomerism risk factor #6
volvulus isomerism #6
logistic regression isomerism #6
isomerism intestinal malrotation #6
factor volvulus #6
determine isomerism #6
malrotation independent #6
ipaa volvulus #6
admissions isomerism #6
intestinal malrotation volvulus #7
factors volvulus #8
pouch volvulus patients #8
volvulus ipaa #9
soleus muscles ovx #10
pouch esophageal #10
volvulus logistic #11
prophylactic ladd #12
isomerism independent #13
study prognosis study #13
muscles ovx #16
study isomerism #16
isomerism heterotaxy syndrome #16
gastroschisis fed #17
ssis fed #17
infants uncomplicated gastroschisis #17
protocolbased feeding #17
gastroschisis protocol #17
versus delayed closure #17
uncomplicated gastroschisis ssis #17
fed institutional #17
ssis sutured closure #17
gastroschisis ssis #17
ssis differences #17
institutionalspecific protocols #17
gastroschisis feeding practices #17
protocol ssis #18
running mdx #18
abnormalities heterotaxy #19
315 neonates #19
pouch volvulus #22
fed protocol #22
isomerism risk #22
continence multivariable #24
144 arm patients #24
birth continence #24

Key People For Fecal Continence

Top KOLs in the world
Risto Juhana Rintala
anorectal malformations bowel function esophageal atresia
Steven David Wexner
rectal cancer fecal incontinence laparoscopic surgery
Alberto Peña
anorectal malformations fecal incontinence hirschsprung disease
Harry G Lindahl
esophageal atresia anorectal malformations fecal continence
Michael A Kamm
faecal incontinence ulcerative colitis inflammatory bowel disease
Marc A Levitt
anorectal malformations hirschsprung disease fecal incontinence

Rachel M Landisch:Expert Impact

Concepts for whichRachel M Landischhas direct influence:Fecal continence,  Mdx mice,  Injured children,  Ladd procedure,  Pouch volvulus,  Heterotaxy syndrome,  Intestinal volvulus,  Venous thromboembolism vte.

Rachel M Landisch:KOL impact

Concepts related to the work of other authors for whichfor which Rachel M Landisch has influence:Skeletal muscle,  Mdx mice,  Resistance training,  Duchenne muscular dystrophy,  Endurance exercise,  Ovariectomized rats,  Gestational age.



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Department of Surgery, Children’s Hospital of Wisconsin, Milwaukee, WI, USA | Division of Pediatric Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI | Department of Surgery, Children's Hospital of Wisconsin, Milwaukee, Wisc

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