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Flecainide



Dan M Roden #1
Dan M Roden
Center for Precision Medicine, Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee | Divisions of Cardiovascular Medicine and ...
Known for Atrial Fibrillation | African Americans | Genetic Variants | Electronic Medical Records
John Camm MD John Camm #2
John Camm MD John Camm
St George’s University, London, UK | Cardiology, St George's University of London, London, UK | Cardiology Clinical Academic Group, Molecular and Clinical Sciences Institute, ...
Known for Atrial Fibrillation | Myocardial Infarction | Heart Rate | Ventricular Tachycardia

Jeffrey L Anderson #3
Jeffrey L Anderson
University of Utah School of Medicine, Salt lake City, UT, USA | Cardiology Division, Department of Internal Medicine, University of Utah, Salt Lake City, Utah, USA | ...
Known for Myocardial Infarction | Coronary Artery Disease | Atrial Fibrillation | Heart Failure
Gordon J Conard #4
Gordon J Conard
University of Minnesota Departments of Theoretical Statistics Minneapolis | 3M/Riker Laboratories, Inc. St. Paul | University of Minnesota Medical Service, Veterans Affairs ...
Known for Flecainide Acetate | Ventricular Arrhythmias | Gingival Hyperplasia | Human Plasma
Raymond Leon Woosley #5
Raymond Leon Woosley
The University of Arizona, Tucson, AZ, USA | Division of Clinical Data Analytics and Decision Support, Department of Medicine, University of Arizona, College of Medicine - ...
Known for Qt Interval | United States | Antiarrhythmic Drugs | Ventricular Repolarization
Henry J Duff #6
Henry J Duff
Department of Cardiac Sciences, Libin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada. | Division of Cardiology, Libin ...
Known for Ventricular Tachycardia | Sodium Channel | Antiarrhythmic Activity | Invasive Approach
Bramah N Singh #7
Bramah N Singh
Clinical Professor of Medicine, UMDNJ-Robert Wood Johnson School of Medicine, Piscataway, New Jersey | Professor of Clinical Cardiology, Department of Cardiac and Vascular ...
Known for Atrial Fibrillation | Sinus Rhythm | Heart Rate | Calcium Antagonists
RODNEY S BEXTON #8
RODNEY S BEXTON
From the 1Falls and Syncope Service and Institute for Ageing and Health, Newcastle University, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne NE1 4LP, ...
Known for Flecainide Acetate | Carotid Sinus Massage | Emergency Department | Antibiotic Prophylaxis
Stanley Nattel #9
Stanley Nattel
Montreal Heart Institute | IHU LIYRC Institute, Bordeaux, France | Department of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada | Department of ...
Known for Atrial Fibrillation | Heart Failure | Ionic Remodeling | Pulmonary Vein
KEVIN J HELLESTRAND #10
KEVIN J HELLESTRAND
From the Department of Cardiology, St. Bartholomew's Hospital, London, England, and the Department of Cardiology, Royal North Shore Hospital, Sydney, Australia | Department of ...
Known for Flecainide Acetate | Proarrhythmic Effects | Tachycardia Termination | Cardiac Transplantation

Flecainide

[ PUBLICATION ] ... Synopsis: Flecainide1 is a Class I antiarrhythmic drug of the local anaesthetic type. It can be given either intravenously or orally and its pharmacokinetic properties allow relatively ...
Known for Flecainide Patients | Antiarrhythmic Agents | Oral Administration | Ventricular Tachycardia

Reentrant Arrhythmias In The Subacute Infarction Period. The Proarrhythmic Effect...

[ PUBLICATION ] ... that flecainide was associated with an increased incidence of sudden cardiac death in postinfarction patients. The exact mechanism(s) of the proarrhythmic effects of flecainide remain ...
Known for Reentrant Arrhythmias | Proarrhythmic Effects | Myocardial Infarction | Coronary Artery

Ryr2 Channel Inhibition Is The Principal Mechanism Of Flecainide Action In Cpvt

[ PUBLICATION ] ... drug flecainide prevents ventricular tachyarrhythmia in patients with catecholaminergic polymorphic ventricular tachycardia (CPVT), a disease caused by hyperactive RyR2 (cardiac ryanodine ...
Known for Flecainide Action | Principal Mechanism | Ventricular Tachycardia | Release Channel

Effect Of Flecainide Derivatives On Sarcoplasmic Reticulum Calcium Release...

[ PUBLICATION ] ... PURPOSE: Flecainide is a use-dependent blocker of cardiac Na(+) channels. Mechanistic analysis of this block showed that the cationic form of flecainide enters the cytosolic vestibule of ...
Known for Sarcoplasmic Reticulum | Ryanodine Receptor | Calcium Release | Ryr2 Channels

Safety And Efficacy Of Flecainide For Patients With Catecholaminergic Polymorphic...

[ PUBLICATION ] ... investigated. Flecainide is an alternative adjunctive anti-arrhythmic agent known to provide incomplete protection to CPVT patients. METHODS: To investigate the efficacy and tolerability ...
Known for Ventricular Tachycardia | Flecainide Monotherapy | Anti Arrhythmia | Catecholaminergic Polymorphic

Electrophysiological Effects Of Flecainide On Anisotropic Conduction And Reentry...

[ PUBLICATION ] ... drug flecainide has been shown to be ineffective for the treatment of ventricular arrhythmias in some patients who have had a prior myocardial infarction and sometimes even provoke ...
Known for Flecainide Conduction | Electrophysiological Effects | Reentrant Circuits | Ventricular Tachycardia

Malignant Arrhythmias And Acute Myocardial Ischemia: Interaction Between...

[ PUBLICATION ] ... of flecainide were assessed in 21 anesthetized cats. Ventricular arrhythmias can be reproducibly induced in cats by the combination of acute myocardial ischemia and sympathetic ...
Known for Acute Myocardial Ischemia | Heart Rate | Ventricular Arrhythmias | Autonomic Nervous

Flecainide: A New Class Ic Antidysrhythmic

[ PUBLICATION ] . Flecainide acetate is a new orally active antidysrhythmic agent classified in the Ic category. Flecainide is effective in suppressing 88 to 100 percent of abnormal cardiac rhythms in the form ...
Known for Ventricular Tachycardia | Arrhythmia Agents | Effects Flecainide | Drug Interactions

Effects Of Flecainide On Exercise-Induced Ventricular Arrhythmias And Recurrences...

[ PUBLICATION ] ... that flecainide in addition to conventional drug therapy prevents ventricular arrhythmias in patients with genotype-positive CPVT. OBJECTIVE: To study the efficacy of flecainide in ...
Known for Ventricular Arrhythmias | Flecainide Patients | Exercise Test | Catecholaminergic Polymorphic

Flecainide: Steady State Electrophysiologic Effects In Patients With Remote...

[ PUBLICATION ] ... of flecainide in 24 patients with inducible sustained ventricular arrhythmia and a history of remote myocardial infarction was determined. Flecainide was administered in oral doses ...
Known for Ventricular Tachycardia | Flecainide Patients | Cardiac Cardiac Pacing | Electrophysiologic Study