Prominent publications by Morton F Goldberg

KOL Index score: 30123

BACKGROUND: Traumatic hyphema is the entry of blood into the anterior chamber (the space between the cornea and iris) subsequent to a blow or a projectile striking the eye. Hyphema uncommonly causes permanent loss of vision. Associated trauma (e.g., corneal staining, traumatic cataract, angle recession glaucoma, optic atrophy, etc.) may seriously affect vision. Such complications may lead to permanent impairment of vision. Patients with sickle cell trait/disease may be particularly ...

Known for Traumatic Hyphema |  Medical Interventions |  Aminocaproic Acid |  Secondary Hemorrhage |  Vision Patients
KOL Index score: 21726

BACKGROUND: Traumatic hyphema is the entry of blood into the anterior chamber (the space between the cornea and iris) subsequent to a blow or a projectile striking the eye. Hyphema uncommonly causes permanent loss of vision. Associated trauma (e.g. corneal staining, traumatic cataract, angle recession glaucoma, optic atrophy, etc.) may seriously affect vision. Such complications may lead to permanent impairment of vision. Patients with sickle cell trait/disease may be particularly ...

Known for Traumatic Hyphema |  Medical Interventions |  Secondary Hemorrhage |  Aminocaproic Acid |  Visual Acuity
KOL Index score: 12103

PURPOSE: To evaluate safety and efficacy of the angiostatic agent anecortave acetate, compared with a placebo, for treatment of subfoveal choroidal neovascularization (CNV).

DESIGN: Ongoing masked, randomized, placebo-controlled, parallel evaluation of anecortave acetate (30 mg, 15 mg, and 3 mg) versus a placebo.

PARTICIPANTS: There were 128 eyes of 128 patients with subfoveal CNV secondary to age-related macular degeneration who were enrolled and treated, with 80% (102/128) of eyes ...

Known for Anecortave Acetate |  Macular Degeneration |  Independent Safety Committee |  Angiogenesis Inhibitors |  1 Year
KOL Index score: 10154

PURPOSE: To describe visual acuity and angiographic outcomes of juxtafoveal choroidal neovascularization (CNV) treated with photodynamic therapy and verteporfin (PDT).

METHODS: Four hundred eighty-four consecutive eyes of 446 patients treated with PDT from January 1, 2001, to June 30, 2002, were identified from billing records. Fluorescein angiograms were reviewed retrospectively to identify juxtafoveal CNV. Eligible patients had CNV in which the central boundary of the lesion was ...

Known for Photodynamic Therapy |  Choroidal Neovascularization |  Visual Acuity |  12 Months |  Verteporfin Pdt
KOL Index score: 9875

PURPOSE: To evaluate clinical safety and efficacy of the angiostatic agent anecortave acetate for treatment of subfoveal choroidal neovascularization secondary to AMD.

METHODS: 128 patients were randomized to placebo treatment or one of three anecortave acetate doses. Study medication was administered as a posterior juxtascleral injection onto the posterior scleral surface. Best-corrected logMAR vision was obtained at baseline and follow-up visits. Fluorescein angiograms were evaluated ...

Known for Anecortave Acetate |  Macular Degeneration |  Placebo Treatment |  Visual Acuity |  Patients Amd
KOL Index score: 8951

Purpose: Retinal vascular occlusions in sickle cell anemia patients cause tissue ischemia and the release of angiogenic mediators that promote the development of retinal neovascularization, initiating proliferative sickle retinopathy (PSR). Laser photocoagulation (LPC) has emerged as the most common treatment for PSR. Nonetheless, only two randomized controlled clinical trials have evaluated the use of LPC for PSR, and both failed to definitively demonstrate efficacy of this approach. ...

Known for Proliferative Sickle Retinopathy |  Vegf Psr |  Expression Hif1α |  Retinal Neovascularization |  Hypoxiainducible Factor
KOL Index score: 8904

PURPOSE: To report ocular and renal findings specific to the inheritable entity called papillorenal (also known as renal-coloboma) syndrome and relate these to a common cause.

DESIGN: Observational case series and genetic study.

PARTICIPANTS: Two unrelated probands presenting with absent central retinal vessels and 11 available family members.

TESTING: Doppler ultrasonographic imaging of the optic nerves and kidneys, fluorescein angiography, and genetic testing for PAX2 mutations were ...

Known for Papillorenal Syndrome |  Pax2 Mutations |  Retinal Diseases |  Renal Hypoplasia |  Genetic Testing
KOL Index score: 8821

Photocoagulation of the monkey fundus with an argon-krypton laser photocoagulator was performed. Lesions produced by argon and krypton wavelengths were compared at various power settings, spot sizes, and exposure durations. At low energy levels argon laser lesions appeared clinically stronger than those produced by the krypton mode. Lesions in the foveal area produced with the argon laser demonstrated more extensive microscopic damage to the inner retinal layers than did those produced ...

Known for Krypton Laser |  Retinal Vessels |  Argon Burns |  Bruchs Membrane |  Fundus Oculi
KOL Index score: 8670

To evaluate the usefulness of magnetic resonance imaging (MRI) in the evaluation of leukocoric eyes, the authors studied 28 patients with either leukocoria or intraocular mass with a 1.5-tesla (T) MRI imager. Retinoblastomas were reliably distinguished from Coats' disease, toxocariasis, and persistent hyperplastic primary vitreous on the basis of MRI findings. Calcification cannot be reliably detected on MRI scans. Lesions elevated less than 4 mm may not be detected reliably by MRI at ...

Known for Magnetic Resonance |  Computed Tomography |  Retinoblastoma Mri |  Coats Disease |  Uveal Melanoma
KOL Index score: 8640

In a patient with clinical features of both myoclonus epilepsy ragged-red fibers (MERRF) and Kearns-Sayre syndrome (KSS), we identified a novel guanine-to-adenine mitochondrial DNA (mtDNA) mutation at nucleotide 3255 (G3255A) of the tRNA(Leu(UUR)) gene. Approximately 5% of the skeletal muscle fibers had excessive mitochondria by succinate dehydrogenase histochemistry while a smaller proportion showed cytochrome c oxidase (COX) deficiency. In skeletal muscle, activities of mitochondrial ...

Known for Sayre Syndrome |  Mitochondrial Rna |  Skeletal Muscle |  Sequence Dna |  Merrf Kearns
KOL Index score: 8468

BACKGROUND: Mutations in BEST1 account for autosomal dominant vitreoretinochoroidopathy (ADVIRC), a rare inherited retinal dystrophy with presenile cataracts and incomplete anterior segment development. The long-term clinical findings and visual prognosis of these patients continues to evolve over time.

MATERIALS AND METHODS: The retina was assessed by fundus photography, fluorescein angiography, and spectral domain optical coherence tomography. Sanger dideoxy chain-termination ...

Known for Autosomal Dominant |  Best1 Advirc |  Missense Mutation |  Retinal Diseases |  Fluorescein Angiography
KOL Index score: 7963

PURPOSE: Ocular ischemia from polyarteritis nodosa (PAN) is rare. The authors present a case of multifocal ocular infarction from PAN.

METHODS AND RESULTS: A 70-year-old woman developed hand and foot numbness followed by intermittent blurred vision and binocular horizontal diplopia. Two weeks later, she suddenly lost vision in the right eye from a central retinal artery occlusion and then developed a left anterior ischemic optic neuropathy and bilateral triangular choroidal abnormalities ...

Known for Polyarteritis Nodosa |  Optic Neuropathy |  Choroidal Infarction |  Artery Occlusion |  Central Retinal
KOL Index score: 7899

The recent success of therapies directly targeting the angiogenic mediator, vascular endothelial growth factor (VEGF), for the treatment of proliferative diabetic retinopathy has encouraged clinicians to extend the use of anti-VEGF therapies for the treatment of another ischemic retinal vascular disease, proliferative sickle cell retinopathy (PSR), the most common cause of irreversible blindness in patients with sickle cell disease. However, results from case reports evaluating anti-VEGF ...

Known for Patients Psr |  Sickle Retinopathy |  Retinal Neovascularization |  Angiogenic Factor |  Angiopoietin 4
KOL Index score: 7844

BACKGROUND: One of the largest series of patients with incontinentia pigmenti who have undergone detailed ophthalmologic examination is reported here, including previously unrecognized findings with visually disabling consequences.

METHODS: Thirteen females with incontinentia pigmenti from eight unrelated families were evaluated. The diagnosis of incontinentia pigmenti had been established previously by a referring pediatrician or dermatologist in 12 patients and by the authors in one ...

Known for Incontinentia Pigmenti |  Preschool Diagnosis |  Retinal Manifestations |  Foveal Hypoplasia |  Central Nervous


Morton F Goldberg: Influence Statistics

Sample of concepts for which Morton F Goldberg is among the top experts in the world.
Concept World rank
hunter ciliary body #1
patients traumatic hyphema #1
argon adult anemia #1
functional βa3 crystallin #1
irides congenital megacolon #1
staining traumatic #1
imaging incontinentia #1
macula disease #1
neuroradiologic findings evidence #1
lamp delivery #1
vitreoretinochoroidopathy #1
zeiss short #1
case apmppe #1
produced krypton #1
anastomoses humans #1
attempts neovascular growth #1
mutation sprague #1
heterochromia iridum #1
fundus complications #1
retinal vasculature category #1
comparison dose regimens #1
corneal diameters cataract #1
posterior pole vasculature #1
nonpenetrating administration #1
neonatal ocular conditions #1
pfv edward jackson #1
incontinentia pigmenti findings #1
disease detailed descriptions #1
decades ophthalmic involvement #1
formation ocular fundus #1
sickle cell trait1 #1
photocoagulative treatment #1
visual acuity interventions #1
serous transudation #1
“renal coloboma” syndrome #1
asymmetric retinal disease #1
storage diseases mucopolysaccharidoses #1
abnormal mucopolysaccharides #1
conclusion cutaneous manifestations #1
letters 500 #1
diseases bloodretinal barrier #1
fluorescein development #1
epipapillary fibroglial tissue #1
diseases major pathogeneses #1
literature retinal vascular #1
origin blood vessels #1
papillary burns monkeys #1
neural parenchymal damage #1
slitlamp delivery valid #1
vital sign testing #1

Key People For Incontinentia Pigmenti

Top KOLs in the world
Dian Donnai
kabuki syndrome human pair genetic counselling
Sara J Landy
incontinentia pigmenti candidate gene disorders nails
Christine Bodemer
netherton syndrome incontinentia pigmenti epidermolysis bullosa
Asma Smahi
incontinentia pigmenti ectodermal dysplasia congenital tufting enteropathy
Morton F Goldberg
incontinentia pigmenti traumatic hyphema sickle cell
Munnich Munnich
respiratory chain hirschsprung disease human pair

Morton F Goldberg:Expert Impact

Concepts for whichMorton F Goldberghas direct influence:Incontinentia pigmenti,  Traumatic hyphema,  Sickle cell,  Argon laser photocoagulation,  Fluorescein angiography,  Proliferative sickle retinopathy,  Visual acuity,  Argon laser.

Morton F Goldberg:KOL impact

Concepts related to the work of other authors for whichfor which Morton F Goldberg has influence:Sickle cell disease,  Diabetic retinopathy,  Incontinentia pigmenti,  Visual acuity,  Retinal detachment,  Fluorescein angiography,  Macular edema.



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Johns Hopkins Medical Institutions, Baltimore, USA | Retina Division, Wilmer Eye Institute, The Johns Hopkins University School of Medicine and Hospital, Baltimore, Maryland | Department of Ophthalmology, Johns Hopkins Medical Institutions, Baltimore

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