• Disease
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  • Major Allergen
  • Elide Anna Pastorello

    Prominent publications by Elide Anna Pastorello

    KOL Index score: 16135

    BACKGROUND: In central and northern Europe food allergy to fruits of the Rosaceae family is strongly associated with birch pollinosis because of the existence of IgE cross-reactive homologous allergens in birch pollen and food. By contrast, in the Mediterranean population allergic reactions to these fruits frequently are not related to birch pollen allergy and are predominantly elicited by lipid transfer proteins (LTPs).

    OBJECTIVE: We sought to determine the prevalence of IgE ...

    Also Ranks for: Cherry Allergy |  recombinant allergens |  vitro diagnosis |  birch pollen |  ige reactivity
    KOL Index score: 14949

    BACKGROUND: Allergy to fresh fruits and vegetables is mostly observed in subjects with pollinosis, especially from birch, because of cross-reacting allergens in vegetable foods and pollens. However, allergic reactions to fruits, specifically Rosaceae fruits, have been reported in subjects without pollinosis.

    OBJECTIVE: This study evaluated the pattern of IgE reactivity, identifying the allergen responsible in 2 groups of patients with oral allergy syndrome to peach with or without birch ...

    Also Ranks for: Major Allergen |  lipid transfer protein |  prunus persica |  plant blotting |  birch pollinosis
    KOL Index score: 14685

    BACKGROUND: Only a few food allergens have as yet been identified, mainly because of the difficulty of obtaining a sufficient number of patients who are clinically sensitized to a given food. This is more feasible in the case of the oral allergy syndrome (OAS), a common form of food allergy, which is especially prevalent in patients with pollinosis.

    OBJECTIVE: We designed a study to identify the allergens of kiwi fruit (Actinidia chinensis) by analyzing the sera of patients with OAS for ...

    Also Ranks for: Kiwi Fruit |  birch pollen |  allergenic components |  cross reactivity |  major allergen
    KOL Index score: 14302

    BACKGROUND: Investigations meeting current standards are limited for the effect of house dust mite (HDM) allergy immunotherapy in asthmatic patients.

    OBJECTIVE: This trial investigated the efficacy and safety of a standardized quality (SQ; allergen standardization method proprietary to the trial sponsor) HDM SLIT-tablet (ALK, Hørsholm, Denmark) in adults and adolescents with HDM respiratory allergic disease. This publication reports the results of the endpoints related to ...

    Also Ranks for: Asthma Control |  inhaled corticosteroid |  standardized quality |  inhalation administration |  6 sqhdm
    KOL Index score: 12978

    BACKGROUND: Only a few studies have investigated the clinical role of food allergens, especially the relationship between sensitization to a given allergen and occurrence of adverse reactions when eating the relevant food item.

    OBJECTIVE: This study evaluated the clinical role of the allergens of Brazil nut by comparing the patterns of IgE binding in sera from 11 patients with anaphylaxis after eating Brazil nuts with those from 10 subjects with no symptoms to this food item. Both groups ...

    Also Ranks for: Brazil Nut |  major allergen |  2s albumin |  clinical expression |  ige binding
    KOL Index score: 12921

    One hundred adult patients with a history of oral allergy syndrome (OAS) after ingestion of fruits and vegetables, 77 patients with hay fever and 13 with skin prick tests and RAST positive to pollens but without seasonal symptoms, and 32 normal nonallergic control subjects, had Phadebas RAST and skin prick tests with commercial extracts (CSPT) and with fresh foods (FFSPT) to assess the reliability of these three tests. Sensitivity was better with FFSPT for carrot, celery, cherry, apple, ...

    Also Ranks for: Skin Prick Tests |  fresh foods |  oral allergy syndrome |  apple carrot |  food extracts
    KOL Index score: 12564

    BACKGROUND: The observation of mugwort-specific IgE antibodies in patients with peach allergy suggests that mugwort sensitization might play a role in sensitization to peach.

    OBJECTIVE: We sought to study the clinical manifestations of mugwort hypersensitivity in patients with peach allergy, identify the common allergens, and evaluate their IgE crossreactivity.

    METHODS: Patients with oral allergy syndrome for peach and specific IgE antibodies to mugwort were investigated for respiratory ...

    Also Ranks for: Peach Allergy |  artemisia vulgaris |  clinical expression |  lipid transfer protein |  allergens antigens
    KOL Index score: 12491

    BACKGROUND: Few allergic reactions to grape are reported in the literature. In some cases an association with peach and cherry allergy was observed. No IgE-mediated reactions to wine have been described, and no grape major allergens have yet been identified.

    OBJECTIVE: We describe several severe reactions to grape or wine. We characterized the grape major allergens and tried to identify the allergen in wine.

    METHODS: We collected documented histories of allergic reactions to grape and ...

    Also Ranks for: Grape Wine |  allergic reactions |  transfer protein |  peach ltp |  major allergen
    KOL Index score: 12491

    BACKGROUND: Oral allergy syndrome in response to fruits and vegetables frequently occurs as clusters of hypersensitivity to members of the same botanical family, for which the immunologic basis lies in a number of common allergens, most of them still unidentified.

    OBJECTIVE: This study was designed to assess the in vivo and in vitro cross-reactivity between fruits of the Prunoideae subfamily (i.e., peach, cherry, apricot, and plum) and to identify their major allergens and the ...

    Also Ranks for: Oral Allergy Syndrome |  cross reactivity |  major allergens |  vivo study |  pollen skin tests
    KOL Index score: 12356

    BACKGROUND: Allergy to apple is commonly associated with birch pollinosis because the two share homologous allergens. However, some patients have apple allergy but no birch pollinosis, suggesting that there are allergens that do not cross-react with birch.

    OBJECTIVE: The aim of the study was to evaluate the IgE reactivity pattern to an apple extract in subjects with allergic reactions to apple, with and without birch hay fever.

    METHODS: Forty-three patients with oral allergy syndrome for ...

    Also Ranks for: Lipid Transfer Protein |  birch pollinosis |  clinical role |  patients apple allergy |  gel chromatography
    KOL Index score: 11413

    BACKGROUND: Apricots are widely grown in Europe, and allergic reactions are becoming more common, especially oral allergy syndrome. Apricot belongs to the botanical subfamily of Prunoideae, which includes peach, the major allergen of which was identified as a 9-kd protein, a lipid transfer protein (LTP).

    OBJECTIVE: The aim of the study was to evaluate the IgE reactivity pattern to an apricot extract in subjects with allergic reactions to apricot, as demonstrated by a positive oral ...

    Also Ranks for: Major Allergen |  lipid transfer protein |  apricot ltp |  allergic reactions |  oral allergy syndrome
    KOL Index score: 11405

    BACKGROUND: The hazelnut major allergens identified to date are an 18-kd protein homologous to Bet v 1 and a 14-kd allergen homologous to Bet v 2. No studies have reported hazelnut allergens recognized in patients with positive double-blind, placebo-controlled food challenge (DBPCFC) results or in patients allergic to hazelnut but not to birch.

    OBJECTIVE: We characterized the hazelnut allergens by studying the IgE reactivity of 65 patients with positive DBPCFC results and 7 patients with ...

    Also Ranks for: Major Allergen |  patients hazelnut |  controlled food |  ige reactivity |  positive dbpcfc
    KOL Index score: 11393

    BACKGROUND: The detection of specific IgE antibodies to environmental allergens does not always coincide with a diagnosis of clinically evident allergic disease, because some patients with positive skin and/or in vitro test results have no symptoms related to the allergen or allergens that induced the antibodies.

    OBJECTIVE: In a multicenter study the optimal cutoff values for specific IgE antibody levels and skin test results that could discriminate between patients with symptomatic and ...

    Also Ranks for: Specific Ige |  skin test |  seasonal sensitivity |  allergy patients |  cutoff values
    KOL Index score: 11031

    BACKGROUND: Three main problems hamper the identification of wheat food allergens: (1) lack of a standardized procedure for extracting all of the wheat protein fractions; (2) absence of double-blind, placebo-controlled food challenge studies that compare the allergenic profile of Osborne's three protein fractions in subjects with real wheat allergy, and (3) lack of data on the differences in IgE-binding capacity between raw and cooked wheat.

    METHODS: Sera of 16 wheat-challenge-positive ...

    Also Ranks for: Food Allergy |  lipid transfer proteins |  amylase inhibitors |  grass pollen |  wheat allergens
    KOL Index score: 10866

    BACKGROUND: Tree nuts are a common cause of food allergy in Europe. However, few studies deal with real food allergy to hazelnuts in subjects believed to be allergic to this food.

    OBJECTIVE: We sought to select subjects with a history of allergic reactions on ingestion of hazelnut and determine how many of these have true allergy by means of the double-blind, placebo-controlled food challenge (DBPCFC).

    METHODS: Eighty-six subjects with a history of symptoms after hazelnut ingestion were ...

    Also Ranks for: Hazelnut Allergy |  skin tests |  food challenge |  sensitivity positive predictive |  positive dbpcfc


    Elide Anna Pastorello: Influence Statistics

    Sample of concepts for which Elide Anna Pastorello is among the top experts in the world.
    Concept World rank
    symptoms pru #1
    prunoideae subfamily peach #1
    prunoideae vitro #1
    pollinosis recognized #1
    judaica patients #1
    life allergic patients #1
    allergens kiwi #1
    birchpollen extracts tolerance #1
    binding almond #1
    nut major allergen #1
    reactivity timothy #1
    food allergy vegetables #1
    peach major #1
    albumin conglutin #1
    nose delayed hypersensitivity #1
    tomato ltp #1
    peach allergies #1
    plum major allergens #1
    mugwort hypersensitivity #1
    tri 14 sensitization #1
    allergenic proteins patients #1
    reintroduced diet #1
    allergic etiology #1
    endochitinase 4a #1
    patients ige immunoblotting #1
    patients apricot #1
    mite tropomyosin #1
    tomato ltp allergen #1
    pru prup3specific tcls #1
    alginateconjugated extract #1
    30 45kd proteins #1
    plum cherry #1
    chitinases food #1
    kd ltp #1
    wine ltp #1
    syndrome trees prunoideae #1
    spt fish #1
    peach specific ige #1
    chemically peeled #1
    inspiratory nasal resistance #1
    influence technological treatments #1

    Key People For Major Allergen

    Top KOLs in the world
    Rudolf Valenta
    grass pollen allergic patients allergenic activity
    Thomas A E Platts‐Mills
    dust mite atopic dermatitis ige antibody
    Dietrich Kraft
    birch pollen timothy grass major allergen
    Martin D Chapman
    dust mite monoclonal antibodies major allergen
    Christof Ebner
    birch pollen major allergen recombinant bet
    Heimo Breiteneder
    birch pollen plant food major allergen

    Elide Anna Pastorello:Expert Impact

    Concepts for whichElide Anna Pastorellohas direct influence:Major allergen,  Food allergy,  Serum tryptase,  Lipid transfer protein,  Hymenoptera venom,  Kiwi fruit,  Perennial rhinitis,  Amino acid.

    Elide Anna Pastorello:KOL impact

    Concepts related to the work of other authors for whichfor which Elide Anna Pastorello has influence:Food allergy,  Allergic rhinitis,  Allergen immunotherapy,  Specific ige,  Atopic dermatitis,  Birch pollen,  Skin tests.



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    Allergy and Immunology, Niguarda Hospital, Milano, Italy | Allergy & Immunology, Niguarda Hospital, Milano, Italy | Struttura Complessa di Allergologia e Immunologia, ASST GOM Niguarda, Milan, Italy | Unit of Allergology and Immunology, ASST Grande O