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    • Lee Joseph Melton,
    • Lee Joseph Melton,: Influence Statistics

      Lee Joseph Melton,

      Lee Joseph Melton,

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      Divisions of Epidemiology. | O. Ni Mhuircheartaigh, MB, BCh, BAO, BSc, MRCPI, St. Vincent's Hospital; C.S. Crowson, MS, Division of Biomedical Statistics and Informatics, ...

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      Lee Joseph Melton :Expert Impact

      Concepts for whichLee Joseph Melton has direct influence:Olmsted county,Fracture risk,Hip fracture,Irritable bowel syndrome,Hip fractures,United states,Venous thromboembolism,Postmenopausal women.

      Lee Joseph Melton :KOL impact

      Concepts related to the work of other authors for whichfor which Lee Joseph Melton has influence:Hip fracture,Venous thromboembolism,Bone mineral density,Postmenopausal women,Celiac disease,Breast cancer,Multiple myeloma.

      KOL Resume for Lee Joseph Melton,

      Year
      2018

      Divisions of Epidemiology.

      2017

      O. Ni Mhuircheartaigh, MB, BCh, BAO, BSc, MRCPI, St. Vincent's Hospital; C.S. Crowson, MS, Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, and Division of Rheumatology, Department of Medicine, Mayo Clinic; S.E. Gabriel, MD, MSc, Rutgers Robert Wood Johnson Medical School; V.L. Roger, MD, MPH, Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic and Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic; L.J. Melton III, MD, MPH, Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic; S. Amin, MD, CM, MPH, Division of Rheumatology, Department of Medicine, Mayo Clinic, and Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic.

      Mayo Clinic Division of Epidemiology Rochester MN USA

      2016

      Department of Health Sciences Research, Division of Epidemiology, Mayo Clinic, Rochester, MN, USA

      2015

      Division of Epidemiology, Mayo Clinic, Rochester, MN, USA

      Departments of Health Sciences Research (H.M.K., J.E.R., C.M.W.-W., and L.J.M.) and Orthopedic Surgery (P.M.H.), Mayo Clinic, 200 First Street S.W., Rochester, MN 55905. E-mail address for H.M. Kremers:

      2014

      Department of Health Sciences Research, Mayo Clinic Division of Epidemiology Rochester MN USA

      Division of Epidemiology, Mayo Clinic, Rochester, Minnesota

      2013

      Division of Epidemiology, Mayo Clinic, Rochester, MN

      Department of Health Sciences Research, College of Medicine, Mayo Clinic, Rochester, Minn

      2012

      Division of Epidemiology, Department of Health Sciences Research, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA

      Epidemiology, College of Medicine, Mayo Clinic, Rochester, MN

      Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota

      2011

      Endocrine Research Unit, College of Medicine, Mayo ClinicRochester, MN, USA

      Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Department of Internal Medicine, Mayo Clinic, Rochester, Minn

      Epidemiology,

      Health Sciences Research (E.J.A., S.J.A., L.J.M.)

      2010

      Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA

      Division of Informatics and Epidemiology, College of Medicine, Mayo Clinic, Rochester, Minnesota

      2009

      Department of Health Sciences Research, Division of Epidemiology, Mayo Clinic, Rochester, Minnesota, USA

      From the Divisions of Gynecologic Surgery, Biomedical Informatics and Biostatistics; Epidemiology; and Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, Rochester, Minnesota., From the Divisions of Gynecologic Surgery, Biomedical Informatics and Biostatistics; Epidemiology; and Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, Rochester, Minnesota.

      Divisions of Epidemiology and Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, Rochester, MN

      2008

      Division of Epidemiology, Mayo Clinic College of Medicine, Rochester, Minnesota

      Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN

      Eli Lilly & Company, Indianapolis, Indiana

      National Osteoporosis Foundation Guide Committee

      Maine Center for Osteoporosis Research and Education, Bangor, Maine

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      Sample of concepts for which Lee Joseph Melton, is among the top experts in the world.
      Concept World rank
      insulin hip bmd #1
      authorization patients #1
      nh admission cases #1
      vbmd bio #1
      female humans minnesota #1
      authorization bias #1
      vte polymorphisms #1
      age trabecular bv #1
      smr ast #1
      95 microstructure #1
      time radiographic #1
      natural fgid #1
      igfbp2 age #1
      expenditures fractures #1
      henry plummer #1
      women estrogen deficiency #1
      n2115 #1
      colorectal polyps 1 #1
      rep medical records #1
      symptoms trial #1
      osteoporosis older women #1
      risk malignant neoplasm #1
      baseline deformity definition #1
      cost morbidity #1
      17398 patients #1
      potential candidates treatment #1
      alcohol nonnicotine drugs #1
      mayo clinic tsr #1
      age matched subjects #1
      structural parameters women #1
      women 100000 population #1
      women thyroidectomy #1
      gastroesophageal reflux survival #1
      evacuation pubococcygeal angles #1
      bmd bmad age #1
      rep census #1
      older adults fnbmd #1
      specific fracture cascade #1
      δls #1
      highresolution pqct #1
      severe qol #1
      gei complications #1
      county residents #1
      usfrax #1
      bilateral oophorectomy onset #1
      threshold defecation disorders #1
      uc fracture risk #1
      mgus 100000 population #1
      901 cases #1
      29 ppv #1
      Sign-in to see all concepts, it's free!

      Prominent publications by Lee Joseph Melton,

      KOL-Index: 22962

      The relationship between BMD and fracture risk was estimated in a meta-analysis of data from 12 cohort studies of approximately 39,000 men and women. Low hip BMD was an important predictor of fracture risk. The prediction of hip fracture with hip BMD also depended on age and z score.

      INTRODUCTION: The aim of this study was to quantify the relationship between BMD and fracture risk and examine the effect of age, sex, time since measurement, and initial BMD value.

      MATERIALS AND METHODS: We ...

      Known for Age Bmd | Risk Hip Fractures | Women 95 | Fracture Hip | Predictive Ability
      KOL-Index: 19832

      The role of the IGFs and IGFBPs on age-related changes in BMD in adult men and women is not well understood. Studying an age-stratified community based sample of 344 men and 276 women, we found higher IGFBP-2 levels to be associated with lower BMD. IGFBP-2, which increases with age in both men and women, was the strongest, most consistent predictor of BMD among the IGF/IGFBPs studied.

      INTRODUCTION: Insulin-like growth factors (IGFs) and their binding proteins (IGFBPs) are important ...

      Known for Postmenopausal Women | Bone Density | Igfbp2 Age | Lower Bmd | Insulin Growth
      KOL-Index: 19228

      OBJECTIVES: To estimate the incidence and determine predictors of venous stasis syndrome and venous ulcers after deep venous thrombosis and pulmonary embolism.

      PATIENTS AND METHODS: This population-based retrospective cohort study reviewed medical records of 1527 patients with incident deep venous thrombosis or pulmonary embolism between 1966 and 1990. We recorded baseline characteristics, event type (deep venous thrombosis with or without pulmonary embolism or pulmonary embolism alone), ...

      Known for Pulmonary Embolism | Venous Stasis Syndrome | Cumulative Incidence | 20 Years | Varicose Ulcer
      KOL-Index: 19069

      It is a common perception that Asians have lower bone density than Caucasians. However, such relationships could be confounded by bone size. In this study, the skeletal status of a convenience sample of 482 men and 887 women living in Hong Kong is compared with published data for Caucasians living in Rochester, Minnesota. Areal bone mineral density (BMD, g/cm2) and volumetric bone mineral apparent density (BMAD, g/cm3) were determined for the lumbar spine and proximal femur, using the ...

      Known for Hong Kong | Bone Density | Lumbar Spine | Caucasians Chinese | Femoral Neck Bmd
      KOL-Index: 17263

      Increasing body weight is associated both with higher bone mass and with lower rates of bone loss. Whether the effects of body weight are mediated by lean body mass (LBM) or fat body mass (FBM) is, however, uncertain because different studies have used different measures of bone mass and arrived at contradictory conclusions. The parameter actually measured is bone mineral content (BMC). Bone mineral density (BMD), bone mineral apparent density (BMAD), and the BMD/height attempt to ...

      Known for Bone Mass | Body Composition | Lbm Fbm | Bmd Bmad | Postmenopausal Women
      KOL-Index: 15796

      Although fat mass is related to bone mineral density (BMD), the potential mechanism(s) of this effect remain to be defined. Thus, we assessed the role of the candidate hormones, leptin, insulin, and estrogen in mediating fat mass effects on the skeleton. Specifically, we related these hormones and fat mass to BMD at the total hip, mid-lateral spine, and mid-distal radius in a sample of 137 premenopausal women (age range 21-54 years), 165 postmenopausal women (34-93 years), and 343 men ...

      Known for Fat Mass | Bmd Women | Leptin Insulin | Bone Density | Potential Mediators
      KOL-Index: 15236

      BACKGROUND: The reported prevalence of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) varies greatly, from 1.9 to 7.7 per 100,000. CIDP is reported to occur more commonly in patients with diabetes mellitus (DM) but has not been rigorously tested.

      OBJECTIVES: To determine the incidence (1982-2001) and prevalence (on January 1, 2000) of CIDP in Olmsted County, Minnesota, and whether DM is more frequent in CIDP.

      METHODS: CIDP was diagnosed by clinical criteria followed by ...

      Known for Diabetes Mellitus | Dm Cidp | Incidence Prevalence | Child Child | Polyradiculoneuropathy Chronic
      KOL-Index: 15219

      Whether the higher serum leptin levels in women are due to gender differences in fat mass or to other factors such as sex steroids remains unclear. In addition to sex steroids, serum insulin levels also appear to be related to leptin levels, although whether this effect is independent of the effects of body composition is unclear. The purpose of this study was to identify the major determinants of circulating serum leptin levels. We studied a large, population-based cohort of 345 men (23 ...

      Known for Leptin Levels | Body Composition | Fat Mass | Sex Steroid | Postmenopausal Women
      KOL-Index: 15092

      BACKGROUND: Dehydroepiandrosterone (DHEA) and testosterone are widely promoted as antiaging supplements, but the long-term benefits, as compared with potential harm, are unknown.

      METHODS: We performed a 2-year, placebo-controlled, randomized, double-blind study involving 87 elderly men with low levels of the sulfated form of DHEA and bioavailable testosterone and 57 elderly women with low levels of sulfated DHEA. Among the men, 29 received DHEA, 27 received testosterone, and 31 received ...

      Known for Elderly Women | Dhea Testosterone | Quality Life | Insulin Sensitivity | Physical Performance
      KOL-Index: 14902

      Low body mass index (BMI) is a well-documented risk factor for future fracture. The aim of this study was to quantify this effect and to explore the association of BMI with fracture risk in relation to age, gender and bone mineral density (BMD) from an international perspective using worldwide data. We studied individual participant data from almost 60,000 men and women from 12 prospective population-based cohorts comprising Rotterdam, EVOS/EPOS, CaMos, Rochester, Sheffield, Dubbo, ...

      Known for Fracture Risk | Bmd Age | Bmi Women | Mass Bone | Sex Factors
      KOL-Index: 14276

      OBJECTIVE: There is increasing laboratory evidence for a neuroprotective effect of estrogen; however, the clinical and epidemiologic evidence remains limited and conflicting. We studied the association of oophorectomy performed before the onset of menopause with the risk of subsequent cognitive impairment or dementia.

      METHODS: We included all women who underwent unilateral or bilateral oophorectomy before the onset of menopause for a non-cancer indication while residing in Olmsted ...

      Known for Cognitive Impairment | Oophorectomy Women | Onset Menopause | Dementia Age | Estrogens Female Humans
      KOL-Index: 14276

      BACKGROUND: The incidence rates of venous stasis syndrome and venous ulcer are uncertain, and trends in incidence are unknown.

      METHODS: We performed a retrospective review of the complete (inpatient and outpatient) medical records of a community population (Olmsted County, Minnesota) to estimate the incidence of venous stasis syndrome and venous ulcer during the 25-year period, 1966 to 1990, and to describe trends in incidence.

      RESULTS: A total of 1131 patients received a first lifetime ...

      Known for Venous Stasis Syndrome | Olmsted County | Incidence Rates | Elderly Population | 100000 Years
      KOL-Index: 14076

      Using QCT, we made a longitudinal, population-based assessment of rates of bone loss over life at the distal radius, distal tibia, and lumbar spine. Cortical bone loss began in perimenopause in women and later in life in men. In contrast, trabecular bone loss began in young adulthood in both sexes.

      INTRODUCTION: Although conventional wisdom holds that bone loss begins at menopause in women and later in life in men, this has not been examined longitudinally in population-based studies ...

      Known for Trabecular Bone | Adult Women | Distal Radius | Lumbar Spine | Loss Age

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      Divisions of Epidemiology. | O. Ni Mhuircheartaigh, MB, BCh, BAO, BSc, MRCPI, St. Vincent's Hospital; C.S. Crowson, MS, Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, and Division of Rheumatology, Departmen

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