• Functional Constipation
    • Marc Alexander Benninga
    • Marc Alexander Benninga: Influence Statistics

      Marc Alexander Benninga

      Marc Alexander Benninga

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      Dept of Pediatric Gastroenterology and Nutrition, Amsterdam University Medical Centers, Emma Children's Hospital, Amsterdam, Netherlands | Department ofPaediatrics, Emma ...

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      Marc Alexander Benninga:Expert Impact

      Concepts for whichMarc Alexander Benningahas direct influence:Functional constipation,Abdominal pain,Fecal incontinence,Childhood constipation,Gastroesophageal reflux,Functional abdominal pain,Functional defecation disorders,Rome iii criteria.

      Marc Alexander Benninga:KOL impact

      Concepts related to the work of other authors for whichfor which Marc Alexander Benninga has influence:Functional constipation,Abdominal pain,Irritable bowel syndrome,Gastroesophageal reflux,Inflammatory bowel disease,Fecal incontinence,Gut microbiota.

      KOL Resume for Marc Alexander Benninga


      Dept of Pediatric Gastroenterology and Nutrition, Amsterdam University Medical Centers, Emma Children's Hospital, Amsterdam, Netherlands


      Pediatric Gastroenterology, Emma Children’s Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands


      Department of Pediatric Gastroenterology, Amsterdam UMC.

      Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Pediatric Gastroenterology, Amsterdam, The Netherlands.

      Pediatric Gastroenterology.


      Department of Pediatric Gastroenterology and Nutrition, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

      Emma Children’s Hospital, Amsterdam UMC, University of Amsterdam, Pediatric Gastroenterology and Nutrition, Amsterdam, The Netherlands

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      Sample of concepts for which Marc Alexander Benninga is among the top experts in the world.
      Concept World rank
      effectiveness pelvic physiotherapy #1
      parental report prevalence #1
      aim analysis children #1
      disordered defecation nnbsd #1
      children firstchoice treatment #1
      presence excessive crying #1
      ibs fapnos fathers #1
      infants rfsi #1
      groups manometric data #1
      3 studies prevalence #1
      young adults constipation #1
      functional dyspepsia children #1
      puberty age factors #1
      practices probiotics #1
      clinical symptoms biomarkers #1
      assessment rfs #1
      interventions fibre #1
      irp distension pressures #1
      constipation health #1
      csa pediatric patients #1
      practices perceived familiarity #1
      hcps parents #1
      abt abt peg #1
      irp4s dci #1
      pediatric ibs faps #1
      valine histidine levels #1
      stis confirmed victims #1
      rair pma #1
      fdds adolescents #1
      ibd patients biomarkers #1
      histologic aberrations #1
      fapd rhamnosus gg #1
      sensation incomplete evacuation #1
      illness perceptions treatment #1
      prognosis constipation #1
      improvement 41 #1
      adults normal motility #1
      parental factors fapnos #1
      smt nausea #1
      relieving pain children #1
      ibd clinical symptoms #1
      disimpaction maintenance treatment #1
      babies infant colic #1
      5 studies cbt #1
      bowel dysfunctions #1
      defecation pattern #1
      ger ppi therapy #1
      ifx steroids #1
      rome criteria infants #1
      fdds overweight obesity #1
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      Prominent publications by Marc Alexander Benninga

      KOL-Index: 13680

      BACKGROUND & AIMS: Functional abdominal pain (FAP) and irritable bowel syndrome (IBS) are highly prevalent in childhood. A substantial proportion of patients continues to experience long-lasting symptoms. Gut-directed hypnotherapy (HT) has been shown to be highly effective in the treatment of adult IBS patients. We undertook a randomized controlled trial and compared clinical effectiveness of HT with standard medical therapy (SMT) in children with FAP or IBS.

      METHODS: Fifty-three ...

      Known for Functional Abdominal Pain | Randomized Controlled Trial | Ht Smt | Irritable Bowel | Fap Ibs
      KOL-Index: 12882

      INTRODUCTION: Use of proton-pump inhibitors (PPIs) for the treatment of gastroesophageal reflux disease (GERD) in children has increased enormously. However, effectiveness and safety of PPIs for pediatric GERD are under debate.

      OBJECTIVES: We performed a systematic review to determine effectiveness and safety of PPIs in children with GERD.

      METHODS: We searched PubMed, Embase, and the Cochrane Database of Systematic Reviews for randomized controlled trials and crossover studies ...

      Known for Ppis Children | Pump Inhibitors | Gerd Symptoms | Gastroesophageal Reflux | Efficacy Safety
      KOL-Index: 12809

      BACKGROUND: Irritable bowel syndrome (IBS) and functional abdominal pain (syndrome) (FAP(S)) are common pediatric disorders, characterized by chronic or recurrent abdominal pain. Treatment is challenging, especially in children with persisting symptoms. Gut-directed hypnotherapy (HT) performed by a therapist has been shown to be effective in these children, but is still unavailable to many children due to costs, a lack of qualified child-hypnotherapists and because it requires a ...

      Known for Irritable Bowel Syndrome | Abdominal Pain | Children Ibs | Qualified Therapists | Directed Hypnotherapy
      KOL-Index: 12430

      IMPORTANCE: An objective assessment of children's competence to consent to research participation is currently not possible. Age limits for asking children's consent vary considerably between countries, and, to our knowledge, the correlation between competence and children's age has never been systematically investigated.

      OBJECTIVES: To test a standardized competence assessment instrument for children by modifying the MacArthur Competence Assessment Tool for Clinical Research ...

      Known for Competence Assessment | Reference Standard | Consent Clinical | Children Age | Humans Informed
      KOL-Index: 12326

      OBJECTIVES: The interrelation between the course of inflammatory bowel disease (IBD) in children and parent's distress, and the subsequent impact this may have on health-related quality of life (HRQOL) of the child is unclear. Therefore, we investigated patient's HRQOL and parental distress and the association between the course of IBD, parental distress, and HRQOL of pediatric patients with IBD.

      METHODS: Pediatric patients with IBD (8-18 years) and parents were invited. Patients ...

      Known for Parental Distress | Inflammatory Bowel | Children Ibd | Life Hrqol | Pediatric Patients
      KOL-Index: 12282

      BACKGROUND AND OBJECTIVE: : Microvillus inclusion disease (MVID) is a rare congenital enteropathy associated with brush border atrophy and reduced expression of enzymes at the enterocytes' apical surface. MVID is associated with mutations in the MYO5B gene, which is expressed in all epithelial tissues. Whether organs other than the intestine are affected in MVID is unclear. We report 2 patients with MVID that developed renal Fanconi syndrome while receiving total parenteral nutrition. ...

      Known for Myo5b Mutations | Renal Fanconi Syndrome | Microvillus Inclusion Disease | Patients Mvid | Epithelial Cells
      KOL-Index: 12223

      Literature on somatization suggests that patients suffering from medically unexplained symptoms are less aware of their emotions and use maladaptive coping strategies when coping with everyday problems. In addition, coping is hypothesized to mediate between emotion awareness and medically unexplained symptoms. Scientific evidence for the relevance of this hypothesis for children with functional abdominal pain (FAP) is, however, lacking. Therefore, the purpose of the present study was to ...

      Known for Emotion Awareness | Abdominal Pain | Medically Unexplained Symptoms | Maladaptive Coping Strategies | Somatoform Disorders
      KOL-Index: 12090

      BACKGROUND: Inconsistent data exist about the efficacy of probiotics in the treatment of constipation. Several studies in adults with constipation showed positive effects of probiotics on constipation. Inconsistent data exist regarding the effect of a single probiotic strain in constipated children. The aim of this pilot study was to determine the effect of a mixture of probiotics containing bifidobacteria and lactobacilli in the treatment of childhood constipation.

      METHODS: Children ...

      Known for Childhood Constipation | Probiotics Mixture | Abdominal Pain | Bms Week | Stool Consistency
      KOL-Index: 11736

      BACKGROUND: A large proportion (25-46%) of adults with inflammatory bowel disease in remission has symptoms of irritable bowel syndrome (IBS), which are thought to reflect ongoing inflammation. Data on paediatric inflammatory bowel disease patients are lacking.

      AIM: To investigate (i) the prevalence of IBS-type symptoms in paediatric inflammatory bowel disease patients in remission and (ii) the relationship of IBS-type symptoms with biochemical markers of disease activity.

      METHODS: This ...

      Known for Bowel Disease | Faecal Calprotectin | Ulcerative Colitis | Ibstype Symptoms | Clinical Remission
      KOL-Index: 11612

      OBJECTIVES: To evaluate among parents of infants and toddlers the agreement between parental report and the Bristol Stool Scale (BSS) in assessing stool consistency and the effect of both methods on determining the prevalence of functional constipation (FC) according to the Rome III criteria.

      STUDY DESIGN: Parents of children ≤48 months of age who were seen for a well-child visit completed a questionnaire about their child's bowel habits during the previous month. Cohen kappa coefficient ...

      Known for Stool Consistency | Rome Iii Criteria | Functional Constipation | Infants Toddlers | Prevalence Child
      KOL-Index: 11361

      OBJECTIVE: To identify a body-positioning regimen that promotes gastric emptying (GE) and reduces gastroesophageal reflux (GER) by changing body position 1 hour after feeding.

      STUDY DESIGN: Ten healthy preterm infants (7 male; mean postmenstrual age, 36 weeks [range, 33 to 38 weeks]) were monitored with combined esophageal impedance-manometry. Infants were positioned in the left lateral position (LLP) or right lateral position (RLP) and then gavage-fed. After 1 hour, the position was ...

      Known for Gastric Emptying | Body Position | Premature Infant | Gastroesophageal Reflux | Rlp Llp
      KOL-Index: 11251

      OBJECTIVES: To determine the prevalence of functional constipation, overweight, and obesity in a cross-sectional observational study among children in Colombia and to examine the association between functional constipation and excessive bodyweight in this population.

      STUDY DESIGN: Demographics, anthropometric data, and questionnaires were collected from 2820 children between 8 and 18 years of age across 4 regions in Colombia. A Spanish translation of the Questionnaire on Pediatric ...

      Known for Functional Constipation | Overweight Obesity | Anthropometric Measurements | Mass Bmi | Excessive Bodyweight
      KOL-Index: 11222

      OBJECTIVE: To assess the health related quality of life (HRQoL) and somatization in school children with constipation.

      STUDY DESIGN: This cross-sectional survey was conducted in children aged 13-18 years, in 4 schools in Gampaha district of Sri Lanka. Data were collected using a pretested, self-administered questionnaire with questions on bowel habits, somatization, and HRQoL. Constipation was diagnosed using Rome III criteria.

      RESULTS: A total of 1792 children were included in the ...

      Known for Constipation Children | Fecal Incontinence | Health Quality Life | Sri Lanka | Lower Hrqol Scores
      KOL-Index: 11155

      OBJECTIVES: Gastric motor abnormalities have been reported in adults with irritable bowel syndrome (IBS), commonly in constipation-predominant IBS (IBS-C); however, such studies are uncommon in children. Furthermore, differences of gastric motility have not been studied in children with different IBS subtypes.

      METHODS: Seventy-six children (33 [43%] boys, age 4-14 years, mean 7.9 years, SD 3.0 years) fulfilling Rome III criteria for IBS and 20 healthy controls (8 [40%] boys, age 4-14 ...

      Known for Antral Motility | Irritable Bowel Syndrome | Children Ibs | Gastric Emptying | Controls Amplitude
      KOL-Index: 10985

      BACKGROUND: Constipation is a frustrating symptom affecting 3% of children worldwide. Randomised controlled trials show that both polyethylene glycol and lactulose are effective in increasing defecation frequency in children with constipation. However, in 30-50%, these children reported abdominal pain, bloating, flatulence, diarrhoea, nausea and bad taste of the medication. Two recent studies have shown that the fermented dairy product containing Bifidobacterium lactis strain DN-173 010 ...

      Known for Bifidobacterium Lactis | Fermented Dairy Product | Defecation Frequency | 3 Weeks | Randomised Controlled

      Key People For Functional Constipation

      Top KOLs in the world
      Marc Alexander Benninga
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      Nicholas Joseph Talley
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      Dept of Pediatric Gastroenterology and Nutrition, Amsterdam University Medical Centers, Emma Children's Hospital, Amsterdam, Netherlands | Department ofPaediatrics, Emma Children's Hospital, Amsterdam University Medical Center, Amsterdam, The Netherl

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