• Gastric Cancer
    • Keizou Sugimachi
    • Keizou Sugimachi : Influence Statistics

      Keizou Sugimachi

      Keizou Sugimachi

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      Department of Surgery, Onga Nakama Medical Association Onga Hospital, Onga-gun, Fukuoka, Japan | Department of Surgery, Onga Nakama Medical Association Onga Hospital, ...

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      Keizou Sugimachi:Expert Impact

      Concepts for whichKeizou Sugimachihas direct influence:Gastric cancer,Hepatocellular carcinoma,Gastric carcinoma,Hepatic resection,Esophageal varices,Esophageal carcinoma,Esophageal cancer,Colorectal cancer.

      Keizou Sugimachi:KOL impact

      Concepts related to the work of other authors for whichfor which Keizou Sugimachi has influence:Gastric cancer,Hepatocellular carcinoma,Liver transplantation,Hepatic resection,Lymph node,Portal hypertension,Tumor cells.

      KOL Resume for Keizou Sugimachi


      Department of Surgery, Onga Nakama Medical Association Onga Hospital, Onga-gun, Fukuoka, Japan


      Department of Surgery, Kyushu University Beppu Hospital, Beppu


      Department of Surgery, Onga Nakama Medical Association, Onga Hospital, Onga-gun, Japan


      Department of Surgery, Kyushu University Beppu Hospital, Tsurumihara 4546, Beppu 874-0838, Japan


      Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan


      Department of Surgery, Kyushu Central Hospital, Fukuoka, Japan


      Department of Surgery II, Faculty of Medicine, Kyushu University, 3–1–1 Maidashi, Higashi‐ku, Fukuoka 812, Japan

      Kushiro Rosai Hospital, Kushiro

      Kyushu Central Hospital, Fukuoka

      Aichi Cancer Center, Nagoya

      St Luke’s Hospital, Tokyo


      General Surgery, Graduate School of Medical Sciences, Kyushu University 60, 3-1-1, Higashi-ku, Fukuoka 812-8582, Japan

      Departments of Surgery and Science


      Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan

      From the Breast Cancer Center, Toyosu Hospital, Showa University School of Medicine; Tokyo Metropolitan Komagome Hospital; Keio University; University of Tokyo; and St Lukes Hospital, Tokyo; Osaka Medical Center for Cancer and Cardiovascular Disease; Osaka University; and Ota Clinic, Osaka; Hiroshima University, Hiroshima; Aichi Cancer Center, Nagoya; Kyusyu University and Oikawa Hospital, Fukuoka; St Marianna University, Kawasaki; Sapporo Medical University and Sapporo Kotoni Breast Clinic, Sapporo;...

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      Sample of concepts for which Keizou Sugimachi is among the top experts in the world.
      Concept World rank
      liver hepatectomy #1
      elevated lesions #1
      lower survival rate #1
      distribution basement membrane #1
      intimal thickness arginine #1
      6h preservation #1
      small gastric carcinoma #1
      serial histologic evaluation #1
      pen type tumors #1
      major hepatic #1
      hyperthermia 5fu #1
      inbreast cancer #1
      mof liver failure #1
      submucosal carcinoma esophagus #1
      middle aged prognosis #1
      thrombin cent #1
      partial hepatic grafting #1
      5fu hyperthermia #1
      palliative reduction surgery #1
      tau variation #1
      metastatic nodules lungs #1
      control intimal thickness #1
      rbt‐1 carcinoma #1
      oesophageal varices dysphagia #1
      carcinoma gastric #1
      funnel type #1
      5fu ht #1
      carcinoma cardia #1
      differentiated gastric carcinoma #1
      hcc dcp level #1
      oesphageal varices #1
      cd45ro hladr #1
      benign tumors carcinoma #1
      metastasis peritoneal #1
      rate adult #1
      groups hyperthermia #1
      waveform pattern #1
      cases recurrence #1
      postoperative chemotherapy uft #1
      noncurative operation #1
      super type #1
      curative total gastrectomy #1
      accurate preoperative estimation #1
      oky survival heart #1
      deletion variant #1
      waveform assessment #1
      hcfu heat #1
      sneg type #1
      metastasis lymph #1
      lugol staining #1
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      Prominent publications by Keizou Sugimachi

      KOL-Index: 17768

      BACKGROUND: Postoperative liver failure is a life-threatening complication after hepatic resection. Because of recent advances in liver surgery technique and a more stringent patient selection, mortality after hepatic resection has steadily decreased, but its incidence still ranges from 10% to 20%. The factors linked to postoperative liver failure in major hepatic resection in the modern era should be reevaluated.

      STUDY DESIGN: Of 80 patients with viral markers (hepatitis C viral ...

      Known for Liver Failure | Major Hepatic Resection | Special Reference | Volumetric Analysis | Diabetes Mellitus
      KOL-Index: 16874

      BACKGROUND: Hematogenous metastasis occurs when cancer cells released from the primary site enter blood vessels and are transported to distant organs, where they attach and proliferate. Angiogenesis is essential for tumor growth and metastasis and depends on the production of angiogenic factors by tumor cells.

      METHODS: We analyzed data on 1184 Japanese adult men and women with gastric cancer with respect to the relation between vascular invasion and the potential for tumor angiogenesis ...

      Known for Vascular Invasion | Tumor Angiogenesis | Gastric Carcinoma | P53 Protein | Expression Vegf
      KOL-Index: 15729

      BACKGROUND: Preoperative elevation of serum C-reactive protein (CRP) has been reported to be a prognostic indicator in gastric carcinoma and colorectal carcinoma. The aim of this study was to establish the significance of preoperative elevation of serum CRP as an indicator of prognosis in patients with esophageal carcinoma.

      METHODS: Two hundred sixty-two patients with esophageal carcinoma who had been treated by esophageal resection and reconstruction of digestive tracts were evaluated, ...

      Known for Preoperative Elevation | Esophageal Carcinoma | Serum Crp | Reactive Protein | Prognostic Indicator
      KOL-Index: 15368

      PURPOSE: Late graft failure is a critical problem, particularly in the presence of poor runoff vessels. Intimal hyperplasia is considered to be the main cause of graft failure. We have already reported that intimal thickening of experimental vein grafts in dogs with poor runoff vessels is more pronounced than that in dogs with normal vessels. We and others also have reported that production of nitric oxide (NO) in the endothelium of canine vein grafts is impaired. In the present study, ...

      Known for Gene Transfer | Intimal Hyperplasia | Vein Grafts | Nitric Oxide | Hemagglutinating Virus
      KOL-Index: 14400

      BACKGROUND: Deaths of living liver donors have been reported in western countries, whereas the morbidity and mortality of such donors in Japan, one of the leading countries for living liver transplantation, have not been reported in detail. We aimed to review the operative morbidity and mortality of such donors in Japan.

      METHODS: 1853 donors of 1852 living liver transplants done in 46 liver transplant centres, and registered in the database of the Japanese Liver Transplantation Society, ...

      Known for Liver Donors | Complications Morbidity | Lateral Segment | Perioperative Mortality | Western Countries
      KOL-Index: 14334

      Activation of endothelial nitric oxide synthase (eNOS) in portal hypertensive (PHT) gastric mucosa leads to hyperdynamic circulation and increased susceptibility to injury. However, the signaling mechanisms for eNOS activation in PHT gastric mucosa and the role of TNF-alpha in this signaling remain unknown. In PHT gastric mucosa we studied (1) eNOS phosphorylation (at serine 1177) required for its activation; (2) association of the phosphatidylinositol 3-kinase (PI 3-kinase), and its ...

      Known for Gastric Mucosa | Akt Activation | Enos Phosphorylation | Portal Hypertensive | Signaling Pathway
      KOL-Index: 14124

      Recent studies suggest the possible therapeutic effect of intramuscular vascular endothelial growth factor (VEGF) gene transfer in individuals with critical limb ischemia. Little information, however, is available regarding (1) the required expression level of VEGF for therapeutic effect, (2) the related expression of endogenous angiogenic factors, including fibroblast growth factor-2 (FGF-2), and (3) the related adverse effects due to overexpression of VEGF. To address these issues, we ...

      Known for Gene Therapy | Critical Limb Ischemia | Fgf2 Vegf | Inbred Balb Mice | Endothelial Growth
      KOL-Index: 13981

      BACKGROUND: Vascular endothelial growth factor (VEGF), a recently identified growth factor with significant angiogenic properties, is a multifunctional angiogenic cytokine that is expressed in many tumors. High VEGF expression has been shown to correlate with the incidence of metastasis and poor prognosis in various cancers. In this study, the authors investigated VEGF expression and microvessel density (MVD) in ductal pancreatic adenocarcinoma and examined the correlations among VEGF ...

      Known for Vegf Expression | Endothelial Growth | Liver Metastasis | Ductal Pancreatic | Clinicopathologic Factors
      KOL-Index: 13584

      The mta1 gene is a recently identified novel candidate metastasis-associated gene. The deduced amino acid sequence contains an src homology-3 domain binding motif, a zinc finger motif and possible phosphorylation sites, suggesting that this gene is involved in signal transduction or regulation of gene expression. The purpose of our study was to examine the mRNA expression levels of the MTA1, the human homologue of the rat mta1 gene in colorectal and gastric carcinomas and thus to ...

      Known for Mta1 Gene | Messenger Rna | Colorectal Carcinomas | Higher Rate | Neoplasm Metastasis
      KOL-Index: 13310

      BACKGROUND: C-reactive protein (CRP) is a product synthesized in hepatocytes and has been reported to be upregulated by such proinflammatory cytokines as interleukin-1, interleukin-6, and tumor necrosis factor. The significance of a preoperative serum elevation in CRP as a predictive indicator for the malignant potential and prognosis in colorectal cancer has not been elucidated.

      METHOD: One hundred and twenty consecutive patients with colorectal cancer, whose local lesions were resected ...

      Known for Preoperative Elevation | Colorectal Cancer | Crp Patients | Reactive Protein | Indicator Prognosis
      KOL-Index: 13119

      BACKGROUND: The aim of this study was to elucidate the usefulness of measuring the positive status of both des-gamma-carboxy prothrombin (DCP) and alpha-fetoprotein (AFP) preoperatively as a new prognostic indicator of hepatocellular carcinoma (HCC).

      METHODS: One hundred forty-seven patients who underwent curative hepatic resection for primary HCC were studied. The definitions of DCP and AFP positivity were: positive DCP > 0.1 AU/ml, and positive AFP > 50 ng/ml. The patients were ...

      Known for Hepatic Resection | Positive Status | Hepatocellular Carcinoma | Dcp Afp | Des‐γ‐carboxy Prothrombin
      KOL-Index: 12947

      p33(ING1) is a novel growth inhibitor candidate for a tumor suppressor gene. p33(ING1) cooperates with p53 and negatively regulates cell growth by activating transcription from the p21/WAF1 promoter even though it has no significant sequence similarity to p53. We first compared p33(ING1) expression in human gastric cancers and matched normal tissues using quantitative RT-PCR and real time 'Taqman TM' technology. A significant decrease in p33(ING1) expression was evident in 15 of 20 ...

      Known for P53 Expression | Tumor Suppressor | Growth Protein | Gastric Cancer | Neoplastic Genes

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      Department of Surgery, Onga Nakama Medical Association Onga Hospital, Onga-gun, Fukuoka, Japan | Department of Surgery, Onga Nakama Medical Association Onga Hospital, Onga-gun, Japan | Department of Surgery, Kyushu University Beppu Hospital, Beppu |

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