Tom R DeMeester: Influence Statistics

Tom R DeMeester

Tom R DeMeester

Keck School of Medicine, University of Southern California, Los Angeles, CA, USA | University of Southern California, Los Angeles, CA, USA | Department of Surgery, Keck School ...

Tom R DeMeester: Expert Impact

Concepts for which Tom R DeMeester has direct influence: Gastroesophageal reflux , Gastroesophageal reflux disease , Intestinal metaplasia , Esophageal adenocarcinoma , Nissen fundoplication , Reflux disease , Antireflux surgery .

Tom R DeMeester: KOL impact

Concepts related to the work of other authors for which for which Tom R DeMeester has influence: Gastroesophageal reflux , Esophageal cancer , Eosinophilic esophagitis , Barrett esophagus , Nissen fundoplication , Hiatal hernia , Intestinal metaplasia .

KOL Resume for Tom R DeMeester

Year
2021

Keck School of Medicine, University of Southern California, Los Angeles, CA, USA

2020

University of Southern California, Los Angeles, CA, USA

2019

Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA. Electronic address:

2018

Keck School of Medicine, University of Southern California, Los Angeles, CA 91108, United States

2017

Department of Surgery Keck School of Medicine University of Southern California Los Angeles, California.

2015

Department of Surgery, Keck Medical Center of University of Southern California, 892 Huntington Garden Drive, San Marino, 91108, Los Angeles, CA, USA

Professor of Surgery, Emeritus, Keck School of Medicine, University of Southern California, San Marino, CA

2014

Department of Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, California

2013

Keck School of Medicine, University of Southern California Department of Surgery Los Angeles California USA

2012

Department of Foregut Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA

Esophageal Diagnostic Working Group, Digestive Disease Week 2011, Chicago, Illinois, USA

2011

Departments of Surgery

1510 San Pablo Street, Suite 514, 90033, Los Angeles, CA, USA

2010

Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, Calif

Foregut Surgery

2009

Departments of Surgery and

Department of Surgery, University of Southern California, Keck School of Medicine, Los Angeles, CA

2008

Department of Surgery, Keck School of Medicine, University of Southern California, 1510 San Pablo Street Suite 514, 90033, Los Angeles, CA, USA

Chief, Division of Thoracic and Foregut Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania

University of Toronto Faculty of Medicine, Senior Surgeon, Division of Thoracic Surgery, The Toronto General Hospital, Toronto, Ontario, Canada

Professor of Surgery, Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio

Daniel and Karen Lee Chair in Thoracic Surgery, Head, Section of General Thoracic Surgery, Cleveland Clinic

2007

Departments of Surgical Pathology and Foregut Surgery, Keck School of Medicine and University of Southern California, Los Angeles, CA

USC – Thoracic and Foregut Surgery, Los Angeles, California and Rochester School of Medicine – Surgery, Rochester, New York, USA

Division of Thoracic Foregut Surgery, Department of Surgery, Keck School of Medicine, University of Southern California (Drs Banki, Mason, Oh, Hagen, S. R. DeMeester, Lipham, Yacoub, and T. R. DeMeester) and Response Genetics Inc (Drs Tanaka and P. V. Danenberg and Ms K. D. Danenberg), Los Angeles.

2006

Departments of Surgery,

KECK School of Medicine, University of Southern California, Los Angeles, California, USA

2005

Departments of Surgery and Cardiothoracic Surgery, Keck School of Medicine, The University of Southern California, Los Angeles, California

2004

Departments of Surgery University of Southern California School of Medicine, Los Angeles, USA

USC, Los Angeles, CA; Response Genetics, Inc., Los Angeles, CA

From the Department of Surgery, University of Southern California, Los Angeles, California.

Prominent publications by Tom R DeMeester

KOL-Index: 20236 . OBJECTIVE: This study was undertaken to investigate the role of the angiogenic factors vascular endothelial growth factor and basic fibroblast growth factor in the development and progression of Barrett esophagus and adenocarcinomas of the esophagus and gastroesophageal junction. METHODS: Vascular endothelial growth factor and basic fibroblast growth factor messenger RNA expression levels, ...
Known for Growth Factor | Barrett Esophagus | Vascular Endothelial | Esophageal Adenocarcinoma
KOL-Index: 18765 . OBJECTIVE: The normal histology at the gastroesophageal junction, and in particular the nature of cardiac mucosa, remains in dispute. Likewise, the relationship of intestinal metaplasia at the gastroesophageal junction (CIM) to Barrett's and intestinal metaplasia of the stomach (GIM) is unclear. The aim of this study was to assess the immunostaining characteristics of cardiac mucosa and ...
Known for Cardiac Mucosa | Cim Barrett | Gastroesophageal Junction | Humans Metaplasia
KOL-Index: 16173 . OBJECTIVE: The aim of this study was to determine whether antireflux surgery is more effective in producing loss of intestinal metaplasia located only at the gastroesophageal junction than it has been in patients with intestinal metaplasia extending up into the distal esophagus. SUMMARY BACKGROUND DATA: Biopsies of a normal appearing gastroesophageal junction will demonstrate cardiac ...
Known for Intestinal Metaplasia | Patients Cim | Esophagus Cardia | Antireflux Procedure
KOL-Index: 16138 . Adenocarcinoma of the distal esophagus and gastroesophageal junction are believed to arise in Barrett's esophagus with intestinal metaplasia. Whether adenocarcinoma can arise in columnar lined esophagus without intestinal metaplasia is in doubt. Whether adenocarcinoma of the gastric cardia arises in intestinal metaplasia of the gastric cardia is also in doubt. We aim to evaluate the ...
Known for Intestinal Metaplasia | Gastric Cardia | Distal Esophagus | Gastroesophageal Junction
KOL-Index: 15556 . Knowledge of the risk of lymph node metastases is critical to planning therapy for T1 esophageal adenocarcinoma. This study retrospectively reviews 75 T1a and 51 T1b tumors and correlates lymph node metastases with depth of tumor invasion, tumor size, presence of lymphovascular invasion, and tumor grade. OBJECTIVES: Increasingly, patients with superficial esophageal adenocarcinoma are ...
Known for Lymph Node Metastases | Tumor Size | Poor Differentiation | Submucosal Invasion
KOL-Index: 15417 . Barrett's esophagus is a multistage polyclonal disease that is associated with the development of adenocarcinoma of the esophagus and esophagogastric junction. Telomerase activation is associated with cellular immortality and carcinogenesis, and increased expression of the telomerase reverse transcriptase catalytic subunit (hTERT) has been used for the early detection of malignant ...
Known for Telomerase Reverse | Patients Cancer | Barrett Esophagus | Neoplastic Humans
KOL-Index: 15372 . OBJECTIVE: The purpose of the study was to test the hypothesis that cardiac mucosa, carditis, and specialized intestinal metaplasia at an endoscopically normal-appearing cardia are manifestations of gastroesophageal reflux disease. SUMMARY BACKGROUND DATA: In the absence of esophageal mucosal injury, the diagnosis of gastroesophageal reflux disease currently rests on 24-hour pH monitoring. ...
Known for Reflux Disease | Cardiac Mucosa | Intestinal Metaplasia | Patients Carditis
KOL-Index: 15161 . OBJECTIVE: The Siewert classification system differentiates between adenocarcinoma of the gastroesophageal junction and that of the distal esophagus. The purpose of this study was to evaluate whether there were differences in the location and prevalence of lymph node metastases, type of recurrence, and survival with these tumors that warrant distinguishing between them in clinical ...
Known for Gastroesophageal Junction | Distal Esophagus | Patients Adenocarcinoma | Survival Esophagectomy
KOL-Index: 14626 . OBJECTIVE: To investigate the prevalence of Barrett's esophagus in patients with adenocarcinomas located at the gastroesophageal junction. DESIGN: A case series of patients who underwent esophagogastrectomy for adenocarcinoma was retrospectively reviewed. Tumors were grouped by location as esophageal, cardiac, and subcardiac, and the prevalence of specialized intestinal metaplasia in the ...
Known for Cardiac Adenocarcinomas | Patients Adenocarcinoma | Barretts Metaplasia | Barrett Esophagus
KOL-Index: 14624 . OBJECTIVE: To assess the long-term outcome of antireflux surgery in patients with Barrett's esophagus. SUMMARY BACKGROUND DATA: The prevalence of Barrett's esophagus is increasing, and its treatment is problematic. Antireflux surgery has the potential to stop reflux and induce a quiescent mucosa. Its long-term outcome, however, has recently been challenged with reports of poor control of ...
Known for Antireflux Surgery | Patients Barrett Esophagus | Reflux Symptoms | Intestinal Metaplasia
KOL-Index: 14332 . The significance of finding specialized intestinal epithelium localized to the region of the gastroesophageal junction is unclear. We tested the hypothesis that short segments of specialized intestinal epithelium are a consequence of gastroesophageal reflux disease and are premalignant. Two hundred forty-one patients with reflux symptoms underwent gastroscopy with rigorous biopsy. ...
Known for Gastroesophageal Reflux Disease | Segment Barrett | Esophagus Patients | Specialized Intestinal
KOL-Index: 14256 . BACKGROUND: The CDX2 (caudal-related homeobox gene 2) and PITX1 (pituitary homeobox 1) genes have essential roles in human development. Forced expression of Cdx2 alone in the murine stomach results in gastric intestinal metaplasia (IM). This study was undertaken to investigate the expression pattern of these critical morphogenesis genes in the Barrett's multistage carcinogenesis ...
Known for Gene Expression | Barretts Esophagus | Pitx1 Homeobox | Esophageal Neoplasms
KOL-Index: 14173 . OBJECTIVE: To compare the frequency and spectrum of p53 gene mutations in adenocarcinomas of the esophagus and cardia and to compare clinical and pathologic features in patients with p53 mutant and nonmutant cancers. SUMMARY BACKGROUND DATA: The p53 gene is commonly mutated in human cancers, and a p53 mutation is reported to be present in more than 50% of esophageal adenocarcinomas. ...
Known for P53 Mutations | Esophagus Cardia | Clinical Significance | Esophagogastric Junction
KOL-Index: 13514 . Background and AimsGastroesophageal reflux disease (GERD) is a spectrum of disease that includes nonerosive reflux disease (NERD), erosive reflux disease (ERD), and Barrett’s esophagus (BE). Treatment outcomes for patients with different stages have differed in many studies. In particular, acid suppressant medication therapy is reported to be less effective for treating patients with NERD ...
Known for Hiatal Hernia | Nissen Fundoplication | Reflux Disease | Lower Esophageal

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Keck School of Medicine, University of Southern California, Los Angeles, CA, USA | University of Southern California, Los Angeles, CA, USA | Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA. Electroni