Vilmos Fülöp

Vilmos Fülöp

Nerc Institute Of Virology And Environmental Microbiology, Mansfield Road, Oxford Ox1 3sr, United Kingdom

Direct Impact

Concepts for which Vilmos Fülöp has direct influence:

gestational trophoblastic
prolyl oligopeptidase
molar pregnancy
active site
normal placenta
crystal structure
breech presentation

External impact

Concepts related to the work of other authors for which Vilmos Fülöp has influence:

prolyl endopeptidase
hydatidiform mole
pseudomonas aeruginosa
breech presentation
paracoccus denitrificans
nitrite reductase
gestational trophoblastic

Prominent publications by Vilmos Fülöp

KOL-Index: 34 INTRODUCTION: Breech presentation is linked to abnormal pregnancy outcomes. However, the causality of this association is unknown. We aimed to investigate predictors of term breech presentation and pregnancy outcomes of breech presentation. MATERIAL AND METHODS: Using a Hungarian registry, all term (≥ 37 weeks), singleton pregnancies with cephalic, and breech presentation in 1996-2011 were ...
Known for
Hungarian Tauffer Obstetric Database | Apgar ≤ | Older Maternal Age | Singleton Pregnancies
KOL-Index: 29 OBJECTIVES: This study aimed to investigate the expression of recently identified matrix metalloproteinases (MMPs), their inhibitors (TIMPs), and inducer (CD147) in a wide range of gestational trophoblastic diseases (GTD) thereby expanding our understanding of the potential role of MMPs in GTD. METHODS: Paraffin sections of 10 normal first-trimester placentas (NP), 10 partial moles (PM), 10 ...
Known for
Mmp-7 | Stronger Staining | Mmps Inhibitors | 5 Choriocarcinomas
KOL-Index: 28 Prolyl oligopeptidase family enzymes regulate the activity of biologically active peptides and peptide hormones, and they are implicated in diseases, including amnesia, depression, diabetes, and trypanosomiasis. Distinctively, these enzymes hydrolyze only relatively short peptide substrates, while large structured peptides and proteins are not usually cleaved. Prolyl oligopeptidase has a ...
Known for
Activity Catalytic | Peptides Peptide | Properties Prolyl | Oligopeptidase Terminal
KOL-Index: 28 The asaccharolytic periodontopathogen Porphyromonas gingivalis produces membrane-anchored proteases such as dipeptidyl peptidase IV that are involved in the destruction of host periodontal tissue. The extracellular domain of this enzyme was overexpressed in Escherichia coli as an N-terminal His-tag fusion protein, purified using standard metal-affinity chromatography and crystallized using ...
Known for
Peptidase Porphyromonas
KOL-Index: 27 TLX antigens have been found on most peripheral blood cells, trophoblasts, seminal vesicle cells and sperms. These antigens seem to be associated with the membrane cofactor protein (MCP) and the CD46 antigen. Alloantibodies to TLX antigens with Fc tau RII-blocking features were obtained by transfusion of leucocytes or platelets. Preliminary population studies revealed that alloantibodies to ...
Known for
Terminology Tlx-B | Trophoblasts | Fcr Blocking Feature | Seminal Vesicle Cells
KOL-Index: 27 A thiamine diphosphate-dependent enzyme annotated as a benzoylformate decarboxylase is encoded by gene cluster ro02984-ro02986 in Rhodococcus jostii RHA1 previously shown to generate vanillin and 4-hydroxybenzaldehyde from lignin oxidation, and a closely related gene cluster is also found in the genome of Pseudomonas fluorescens Pf-5. Two hypotheses for possible pathways involving a thiamine ...
Known for
Recombinant Enzymes | Fluorescens | Pf-5 | Mandelic Acid
KOL-Index: 26 The valorization of aromatic heteropolymer lignin is an important unsolved problem in the development of a biomass-based biorefinery, for which novel high-activity biocatalysts are needed. Sequencing of the genomic DNA of lignin-degrading bacterial strain Sphingobacterium sp. T2 revealed no matches to known lignin-degrading genes. Proteomic matches for two manganese superoxide dismutase ...
Known for
Sphingobacterium Revealed | Mnsod | Activity Oxidation | Matches Manganese
KOL-Index: 26 BACKGROUND AND AIM: Gestational trophoblastic disease (GTD) is a heterogeneous group of disorders characterised by abnormal proliferation of trophoblastic tissue. Since GTD and its malignant sequel gestational trophoblastic neoplasia (GTN) are rare diseases, little evidence is available from randomised controlled trials on optimal treatment and follow-up. Treatment protocols vary within ...
Known for
6 Occasions | Heterogeneous | Gestational | Ultra-High-Risk Gtn
KOL-Index: 24 Oligopeptidase B (OpdB) is a serine peptidase broadly distributed among unicellular eukaryotes, gram-negative bacteria, and spirochetes which has emerged as an important virulence factor and potential therapeutic target in infectious diseases. We report here the cloning and expression of the opdB homologue from Salmonella enterica serovar Typhimurium and demonstrate that it exhibits ...
Known for
Direct Opdb Cleavage Terminal | Residues Pop | Oligopeptidase Opdb | Histone Proteins
KOL-Index: 24 OBJECTIVE: Our purpose was to identify potential differences in gene expression between normal trophoblast and choriocarcinoma cells. METHODS: The Atlas human cDNA expression array hybridization technique was used to study the gene expression pattern in normal trophoblast and choriocarcinoma cell lines. Furthermore, to confirm heat shock protein-27 (Hsp-27) expression data, reverse ...
Known for
Hsp-27 Expression | Trophoblast Cells | Paraffin Sections | Extreme Sensitivity

NERC Institute of Virology and Environmental Microbiology, Mansfield Road, Oxford OX1 3SR, United Kingdom

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