• Disease
  • Alcohol
  • Alcohol Withdrawal
  • Adam Bryce Weinfeld

    Prominent publications by Adam Bryce Weinfeld

    KOL Index score: 13843

    The present investigation evaluates the effects of long-term, local delivery of insulin, insulin-like growth factor-1 (IGF-1), and basic fibroblast growth factor (bFGF) on fat-graft survival using a poly (lactic-co-glycolic-acid)-polyethylene glycol (PLGA/PEG) microsphere delivery system. Twelve-micrometer PLGA/PEG microspheres incorporated separately with insulin, IGF-1, and bFGF were manufactured using a double-emulsion solvent-extraction technique. Inguinal fat from Sprague Dawley ...

    Also Ranks for: Growth Factor |  graft survival |  local delivery |  insulin igf1 |  plga peg
    KOL Index score: 9991

    This study was undertaken to characterize the duration of long-term growth factor delivery by poly(lactic-co-glycolic-acid)-polyethylene glycol (PLGA/PEG) microspheres and to evaluate the potential of long-term delivery of insulin and insulin-like growth factor-1 (IGF-1) for the de novo generation of adipose tissue in vivo. PLGA/PEG microspheres containing insulin and IGF-1, separately, were produced by a double-emulsion solvent-extraction technique. In the first phase of the experiment, ...

    Also Ranks for: Adipose Tissue |  growth factor |  plga peg |  adipogenic differentiation |  4 weeks
    KOL Index score: 8506

    BACKGROUND: The purpose of this study was to identify the environmental factors that contribute to facial aging in identical twins.

    METHODS: During the Twins Day Festival in Twinsburg, Ohio, 186 pairs of identical twins completed a comprehensive questionnaire, and digital images were obtained. A panel reviewed the images independently and recorded the differences in the perceived twins' ages and their facial features. The perceived age differences were then correlated with multiple ...

    Also Ranks for: Facial Aging |  identical twins |  sun exposure |  environmental factors |  comprehensive questionnaire
    KOL Index score: 7286

    This paper presents 4 consecutive cases using negative-pressure dressings (VAC) to bolster skin grafts in male genital reconstruction. In this series reconstruction followed 1 case of tumor ablation and 3 cases of debridement of abscesses or Fornier's gangrene. The VAC was applied circumferentially to the penis to secure skin grafts either directly to the penile shaft or to facilitate skin grafting to the scrotum. Graft areas ranged from 75 to 250 cm. All cases resulted in successful ...

    Also Ranks for: Skin Grafts |  penile shaft |  male genitalia |  3 cases |  negativepressure dressings
    KOL Index score: 6609

    The adipofascial flaps currently described in the literature frequently lack the volume requirements for reconstructive goals. In this study, the authors examined the use of long-term local delivery of insulin and insulin-like growth factor-1 (IGF-1) using polylactic-coglycolic acid/polyethylene glycol (PLGA/PEG) microspheres to augment inguinal adipofascial flaps based on the inferior epigastric vessels in the rat. Two flap models, the island flap and the limited dissection flap, were ...

    Also Ranks for: Growth Factor |  adipofascial flaps |  plga peg |  cell proliferation |  mature adipocytes
    KOL Index score: 6595

    Partial median-nerve injury high in the upper extremity, resulting from brachial plexus neuritis or trauma, can affect the pronator teres muscle and result in the inability to pronate the forearm. A nerve transfer from an ulnar nerve-innervated branch to the flexor carpi ulnaris (FCU) muscle to the branch to the pronator teres (PT) is an attractive option in this clinical scenario. This study, a histomorphometric analysis of nine cadaver specimens harvested at the proposed FCU branch to ...

    Also Ranks for: Ulnar Nerve |  flexor carpi |  pronator teres |  aged muscle |  upper extremity
    KOL Index score: 6129

    Tissue-type plasminogen activator (tPA) catalyzes the rate-limiting initial step in the fibrinolytic cascade. Systemic infusion of tPA has become the standard of care for acute myocardial infarction. However, even the relatively short-duration protocols currently employed have encountered significant hemorrhagic complications, as well as complications from rebound thrombosis. Gene therapy offers a method of local high-level tPA expression over a prolonged time period to avoid both ...

    Also Ranks for: Local Overexpression |  gene therapy |  plasminogen activator |  arterial thrombosis |  adenoviral vector
    KOL Index score: 5887

    Alcohol use is a risk factor for head and neck cancer. One of the primary therapeutic modalities is surgical tumor ablation followed by immediate reconstruction. Such therapy places patients in a controlled environment, without alcohol, creating the risk of alcohol withdrawal syndrome. The authors attempted to identify the incidence of alcohol withdrawal among patients undergoing free-flap reconstruction for head and neck cancer and were interested in the effect of alcohol withdrawal on ...

    Also Ranks for: Alcohol Withdrawal |  neck reconstruction |  retrospective studies |  delirium tremens |  surgical procedures
    KOL Index score: 5587

    BACKGROUND: Chemosis can cause persistent discomfort and aggravation in the postoperative period following surgery of the eyelids. This article focuses on chemosis associated with cosmetic lower blepharoplasty. The cause is multifactorial and includes exposure, periorbital edema, and postoperative lymphatic dysfunction.

    METHODS: A chart review of 312 primary bilateral lower transcutaneous blepharoplasties was performed. Data were collected to identify the incidence of chemosis, define ...

    Also Ranks for: Incidence Chemosis |  lower blepharoplasty |  postoperative complications |  chart review |  3 weeks
    KOL Index score: 5184

    PURPOSE: Indirect evidence suggests that tissue plasminogen activator (tPA) either limits or does not alter restenosis. However, tPA enhances tumor invasiveness through matrix remodeling, and several elements of degraded matrix enhance smooth muscle cell mitogenesis. We use either local adenoviral-mediated overexpression of tPA or systemic infusion of recombinant tPA combined with mechanical overdilation of rabbit common femoral arteries to evaluate the impact of tPA on neointima ...

    Also Ranks for: Neointima Formation |  plasminogen activator |  smooth muscle |  extracellular matrix |  recombinant tpa
    KOL Index score: 4026

    We present a surgical technique of nipple areolar reconstruction that uses a purse-string to increase areolar projection while reducing loss of nipple projection. A permanent purse-string is used around a modified CV flap to advance tissue centrally to the base of the nipple reconstruction. Two opposing hemiareolar island flaps are advanced toward the base of the nipple to add tissue volume. The resulting circumareolar full thickness skin is closed using a permanent purse-string suture. ...

    Also Ranks for: Areolar Reconstruction |  nipple projection |  string suture |  surgical technique |  humans mammaplasty
    KOL Index score: 3795

    Recently there has been a dramatic increase in the number of patients seeking buttocks enhancement and in the degree of augmentation requested. To fulfill these requests,aesthetic plastic surgeons must understand the patient's personal requests and ethnic identity, as well as any universal ideal of proportions and contours that create the impression of beautiful buttocks. "Universally" perceived ideal buttocks are 1.4 times the circumference of the waist, which is consistent ...

    Also Ranks for: Fat Grafting |  universal ideal |  buttock implants |  ethnic differences |  adipose tissue


    Adam Bryce Weinfeld: Influence Statistics

    Sample of concepts for which Adam Bryce Weinfeld is among the top experts in the world.
    Concept World rank
    projection purse #1
    complications leech therapy #1
    areolar projection #2
    chemosis lower #3
    incidence chemosis #4
    techniques tattooing #5
    tenzel #5
    nonviral buffer #5
    microspheres islands #6
    chemosis cosmetic #6
    factor1 plga #6
    islands blank #6
    igf1 adipogenic differentiation #6
    plga peg igf1 #6
    igf1 blank microspheres #6
    plga peg potential #6
    igf1 novo #6
    4 weeks potential #8
    igf1 blank #8
    systemic infusion tpa #9
    early collagenous #9
    determination collagenous #9
    neointima formation overexpression #9
    vacuum bandages #9
    adipocytes nonadipocyte #9
    animals blank microspheres #9
    degree neointima formation #9
    tpa systemic infusion #9
    igf1 microspheres #9
    nonviral buffer control #9
    tpa neointima formation #9
    tpa neointima #9
    systemic infusion degree #9
    controls 7 28 #9
    study groups insulin #10
    local overexpression tpa #10
    islands adipose #10
    ideal buttocks #11
    inguinal adipofascial flaps #11
    expressing tpa #12
    aging identical #12
    enhancement neointima #12
    degree neointima #13
    reconstruction alcohol #13
    factors blepharoplasty #13
    universal ideal #14
    fcu branch #14
    plga peg microspheres #14
    beauty buttocks #14
    potential adipogenic differentiation #14

    Key People For Alcohol Withdrawal

    Top KOLs in the world
    Edward M Sellers
    cytochrome p450 abuse potential ethanol intake
    Claudio A Naranjo
    alcohol intake serotonin uptake inhibitors adverse drug reactions
    Kathy Sykora
    alcohol withdrawal ethanol intake calcium carbimide
    Michael F Mayo‐Smith
    alcohol withdrawal physical diagnosis rhode island
    Raymond F Anton
    alcohol dependence heavy drinking risk levels
    John T Sullivan
    ethanol intake alcohol withdrawal amitriptyline fluoxetine

    Adam Bryce Weinfeld:Expert Impact

    Concepts for whichAdam Bryce Weinfeldhas direct influence:Alcohol withdrawal,  Neointima formation,  Leech therapy,  Facial aging,  Identical twins,  Penile shaft,  Skin grafts,  Ulnar nerve.

    Adam Bryce Weinfeld:KOL impact

    Concepts related to the work of other authors for whichfor which Adam Bryce Weinfeld has influence:Adipose tissue,  Fat grafting,  Gene therapy,  Cleft lip,  Ulnar nerve,  Buried penis,  Medicinal leeches.



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    Physician, Seton Institute of Reconstructive and Plastic Surgery, Seton Family of Hospitals, Austin, TX, USA | Department of Plastic Surgery, Dell Children's Hospital, Austin, Texas. | Seton Institute of Reconstructive Plastic Surgery, University Med