Prominent publications by Henry G Friesen

KOL Index score: 15139

A receptor for prolactin and other lactogenic hormones (human growth hormone and placental lactogens) has been solubilized by 1% (v/v) Triton X-100 from a crude particulate membrane fraction isolated from pregnant rabbit mammary glands. The receptor remained in solution after centrifugation at 200,000 x g for 2 hours. Triton X-100 at concentrations higher than 0.01% (v/v) affected the physical properties of 125I-prolactin, whereas 125I-human growth hormone (hGH) was unaffected and, ...

Known for Prolactin Receptor |  Mammary Gland |  Affinity Chromatography |  Triton X100 |  Gel Electrophoresis
KOL Index score: 14435

Extract: Serum prolactin (HPr) and serum growth hormone (HGH) were determined by double antibody radioimmunoassay methods. Markedly elevated levels of serum prolactin with considerable variation were observed in the neonatal period. No significant difference was observed in six matched arteriovenous cord blood samples. No sex difference was noted in the full term infants, whereas the mean value for 24 premature male infants in the 1st week of life (190 ± 17 ng/ml sem) was significantly ...

Known for Serum Prolactin |  Pituitary Secretion |  Hormone Adolescent |  Normal Subjects |  Arginine Child
KOL Index score: 9978

Receptors for human, simian, ovine, bovine and murine prolactin, human growth hormone and human placental lactogen have been identified in plasma-membrane-containing subcellular particles isolated from rabbit mammary glands. The association and dissociation of (125)I-labelled prolactin are time- and temperature-dependent processes, both being maximal at 37 degrees C. (125)I-labelled prolactin prepared by the enzymic iodination procedure with lactoperoxidase binds better to receptors than ...

Known for Prolactin Receptor |  Rabbit Mammary |  Binding 125i |  Adrenal Gland |  Female Growth
KOL Index score: 9636

Human pituitary prolactin (PRL) is released in a pattern that is different from growth hormone (HGH). Basal PRL concentrations remain unchanged throughout the menstrual cycle and bear no apparent relationship to the cyclic change in gonadotropins. Significant increases in PRL occur after intramuscular chlorpromazine (CPZ). The response is dose related. These results correlate with PRL values measured in patients ingesting large amounts of phenothiazines for psychiatric disease. ...

Known for Growth Hormone |  Human Prolactin |  Intravenous Trh |  Response Nursing |  Prl Basal Prl
KOL Index score: 9328

A radioimmunoassay for primate prolactin has been developed, with [(131)I] monkey prolactin, and antibodies to monkey or human prolactin. The assay is specific for prolactin; human growth hormone, and human and monkey placental lactogen show no significant crossreaction. The assay is sensitive enough to measure prolactin concentrations in the sera of most humans studied. The concentration of prolactin in the serum of normal children and adults of either sex was usually below 30 ng/ml, ...

Known for Human Prolactin |  Concentration Serum |  Menstrual Cycle |  Luteal Phase |  Normal Range


Henry G Friesen: Influence Statistics

Sample of concepts for which Henry G Friesen is among the top experts in the world.
Concept World rank
clonal im9p3 cell #1
rat radioreceptor #1
brain srif content #1
566 mm highk #1
hgh nb2 cells #1
cultured chromatography cgf #1
fgf1 human pituitaries #1
hypophysectomy major reduction #1
tpa nb2 #1
anestrus betaendorphin concentrations #1
nb2 rat lymphoma #1
normal abnormal gestation #1
gh squirrel #1
immunoreactive somatostatin amygdala #1
sb prl #1
frequent dissociation eeg #1
nb2 cells met14hgh #1
65 galactorrheic individuals #1
prolactin lactogenic #1
tissues456 #1
route comparable effects #1
awake habituated #1
pregnancy rat placenta #1
surface sheep #1
βendorphin highest concentrations #1
prolactin medicated schizophrenics #1
pituitary chlorpromazine #1
peptides rapid increase #1
untreated hypothalamic #1
human prolactin methods #1
teleocalcin monomer mw #1
menstrual gestational women #1
im9p3 prl #1
local growth response #1
antiserum salmon #1
cell surface radioreceptor #1
porcine galanin precursor #1
radioligand assay somatomedins #1
physical stimulation pregnancy #1
findings neuroleptic medications #1
βendorphin methodologies #1
inactive iodinated hormone #1
23 expression uterus #1
induced effects administration #1
radioreceptor assay data #1
bromocryptine symptoms #1
porcine neurophysin peptide #1
purification human prolactin #1
argonzdel castillo syndrome #1

Key People For Growth Hormone

Top KOLs in the world
Michael O Thorner
growth hormone gh secretion prolactin release
Ron G Rosenfeld
growth factor binding protein turner syndrome
Raymond L Hintz
growth factor insulin receptors binding proteins
Jens Sandahl Sandahl Christiansen
growth hormone body composition turner syndrome
BengtÅke NÅ Bengtsson†
growth hormone body composition gh replacement
David Robert Clemmons
growth factor binding protein smooth muscle

Henry G Friesen:Expert Impact

Concepts for whichHenry G Friesenhas direct influence:Growth hormone,  Placental lactogen,  Prolactin secretion,  Human pituitary,  Immunoreactive somatostatin,  Squirrel monkey,  Pituitary gland,  Human prolactin.

Henry G Friesen:KOL impact

Concepts related to the work of other authors for whichfor which Henry G Friesen has influence:Growth hormone,  Prolactin receptors,  Placental lactogen,  Gene expression,  Mammary gland,  Maternal behavior,  Anterior pituitary.



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Faculty of Medicine University of Manitoba Winnipeg, Manitoba, Canada R3E 0W3 | Department of Comparative Medicine, Tufts University School of Veterinary Medicine, North Grafton, Mass., USA;, Department of Physiology, University of Manitoba School of

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