Nobuhiro Yuki: Influence Statistics

Nobuhiro Yuki

Nobuhiro Yuki

Department of Neurology, Tsukuba Hospital, Tsukuba, Ibaraki, Japan | Yuki Clinic, 1-3-7 Johnan, Mito, Ibaraki 310-0803, Japan;, gbs.yuki.cidp@gmail.com | Nobuhiro Yuki is at ...

Nobuhiro Yuki: Expert Impact

Concepts for which Nobuhiro Yuki has direct influence: Barré syndrome , Fisher syndrome , Campylobacter jejuni , Guillainbarré syndrome , Chronic inflammatory , Miller fisher syndrome , Igg antibody .

Nobuhiro Yuki: KOL impact

Concepts related to the work of other authors for which for which Nobuhiro Yuki has influence: Barré syndrome , Campylobacter jejuni , Chronic inflammatory , Intravenous immunoglobulin , Gbs patients , Molecular mimicry , Plasma exchange .

KOL Resume for Nobuhiro Yuki

Year
2021

Department of Neurology, Tsukuba Hospital, Tsukuba, Ibaraki, Japan

2019

Yuki Clinic, 1-3-7 Johnan, Mito, Ibaraki 310-0803, Japan;,

2018

Nobuhiro Yuki is at the Department of Medicine, Eda Memorial Hospital, Azamino-minami 1-1-1, Aoba-ku, Yokohama, Kanagawa, 225-0012, Japan.

2017

Department of Neurology, Mishima Hospital, Niigata 940-2302, Japan

2016

Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore

University of Sydney, Sydney, NSW, Australia.

2015

Departments of Medicine and Physiology, National University of Singapore, Singapore, Singapore

Brain & Mind Research Institute, University of Sydney, Sydney, Australia

Department of Neurology, Dokkyo Medical University, Tochigi 321–0293, Japan

2014

Departments of Medicine and Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Unit 09-01, Centre for Translational Medicine, 14 Medical Drive, 117599, Singapore, Singapore

2013

Department of Neurology, Dokkyo Medical University, Shimotsuga-gun, Tochigi, Japan;, Department of Medicine, Yong Loo Ling School of Medicine, National University of Singapore, Singapore

2012

From the Institute of Clinical Neuroimmunology (J.K.M.N., J.M., N.K., R.H., K.D., E.M.), Ludwig Maximilians University, Munich; Max Planck Institute of Neurobiology (J.K.M.N., J.M., N.K., R.H., K.D., E.M.), Martinsried, Germany; Department of Neurology and Biomedicine (T.D.), University Hospital Basel, Basel, Switzerland; Neuroimmunology Unit (M.K., T.O.), Karolinska University Hospital, Stockholm, Sweden; Division of Clinical Neuroscience (C.L.), University of Glasgow, Glasgow, UK; Department of Neurology (M.O.), Dokkyo Medical University School of Medicine, Tochigi, Japan; Department of Neurology (B.T.), Clinical Neuroimmunology Group, Philipps University, Marburg; Departments of Neurology and Experimental Neurology (H.P., J.M.S., L.H.), Charité, Berlin; Neurology Clinic (H.H.), St. Josef-Krankenhaus, Potsdam; Neurology Clinic (C.S.), University Hospital of Würzburg, Würzburg, Germany; Department of Neuroscience (M.N.R.), Baylor College of Medicine, Houston, TX; Department of Molecular Cell Biology (Y.E.-E., E.P.), Weizmann Institute of Science, Rehovot, Israel; and Department of Medicine (N.Y.), Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

Departments of Microbiology and Medicine, National University of Singapore, 5 Science Drive 2, Blk MD4A, Level 5, 117597, Singapore; Departments of Microbiology and Medicine, National University of Singapore, 5 Science Drive 2, Blk MD4A, Level 5, 117597, Singapore

2011

Departments of Microbiology and Medicine, National University of Singapore, Science Drive 2, Blk MD4A, Level 5, Singapore 117597, Singapore

2010

From the Rudolf Magnus Institute of Neuroscience, Department of Neurology (E.A.C., S.P., J.-T.v.A., L.H.v.d.B., W.-L.v.d.P.), and Department of Clinical Neurophysiology (H.F.), University Medical Center Utrecht; Department of Neurology (B.C.J., A.P.T.-G.), Erasmus Medical Center, Rotterdam, the Netherlands; and Departments of Microbiology and Medicine (N.Y.), National University of Singapore.

Departments of Neurology and Clinical Research, Niigata National Hospital, 3‐52 Akasaka, Kashiwazaki, Niigata 945‐8585, Japan

5 Department of Medicine, National University of Singapore, 117597, Singapore

2009

Niigata National Hospital, Niigata, Japan

Prominent publications by Nobuhiro Yuki

KOL-Index: 18432 . OBJECTIVES: To clarify the nosological relation among Miller Fisher syndrome (MFS), Guillain-Barré syndrome (GBS) with ophthalmoplegia, Bickerstaff's brain stem encephalitis (BBE), and acute ophthalmoparesis without ataxia. Serum samples from patients with each condition often have anti-GQ1b IgG antibody. METHODS: Information on antecedent illness, initial symptoms, neurological signs ...
Known for Bbe Gbs | Igg Anti | Patients Mfs | Acute Ophthalmoparesis
KOL-Index: 14762 . Guillain-Barré syndrome is divided into two major subtypes, acute inflammatory demyelinating polyneuropathy and acute motor axonal neuropathy. The characteristic electrophysiological features of acute motor axonal neuropathy are reduced amplitude or absence of distal compound muscle action potentials indicating axonal degeneration. In contrast, autopsy study results show early nodal ...
Known for Conduction Block | Motor Axonal | Ulnar Nerve | 18 Patients
KOL-Index: 14630 . OBJECTIVE: To investigate the presence of serum anti-GT1a IgG in Guillain-Barré syndrome (GBS) and its relation to clinical manifestations. BACKGROUND: Several patients with GBS and bulbar palsy have been reported to have serum anti-GT1a IgG. Most, however, also have anti-GQ1b IgG. A previous study failed to detect GT1a in human cranial nerves, but GQ1b was abundant in human ocular motor ...
Known for Gt1a Igg | Patients Anti | Barré Syndrome | Clinical Manifestations
KOL-Index: 14057 . To clarify the relations of the axonal form of Guillain-Barré syndrome (GBS) to anti-ganglioside antibodies and Campylobacter jejuni infection, 86 consecutive Japanese GBS patients were studied. Electrodiagnostic criteria showed acute inflammatory demyelinating polyneuropathy in 36% of the patients and acute motor axonal neuropathy (AMAN) in 38%. Frequent anti-ganglioside antibodies were ...
Known for Jejuni Infection | Ganglioside Antibodies | Patients Aman | Axonal Guillain‐barré Syndrome
KOL-Index: 14034 . OBJECTIVES: To investigate the incidence of hyperreflexia in patients with Guillain-Barré syndrome (GBS), and its relation with electrodiagnosis of acute motor axonal neuropathy (AMAN), antiganglioside GM1 antibody, and Campylobacter jejuni infection. It was reported that patients with AMAN in northern China often had hyperreflexia in the recovery phase. METHODS: In 54 consecutive Japanese ...
Known for Patients Hyperreflexia | Acute Motor | Gbs Aman | Barré Syndrome
KOL-Index: 13865 . Neurofascin-186 (NF186), neuronal cell adhesion molecule (NrCAM), and gliomedin are adhesion molecules playing a central role in the formation of nodes of Ranvier. In Guillain-Barré syndrome (GBS), immune attack toward the nodes may participate in the disabilities. Autoantibodies to NF186 and gliomedin have been detected in a rat model of GBS. Here, we investigated the prevalence of ...
Known for Target Antigens | Nodal Proteins | Nf186 Gliomedin | Guillain‐barré Syndrome
KOL-Index: 13191 . IgA has an important function in the gastrointestinal immune system. We investigated IgA anti-ganglioside antibodies in Guillain-Barré syndrome (GBS) and Fisher's syndrome (FS) subsequent to Campylobacter jejuni enteritis. In previous studies, serological diagnosis of C. jejuni infection was based on the detection of IgG, IgA, and IgM anti-C. jejuni antibodies. Our study, however, showed ...
Known for Jejuni Infection | Iga Anti | Gbs Patients | Ganglioside Gangliosides
KOL-Index: 12498 . Autoantibodies against gangliosides GM1 or GD1a are associated with acute motor axonal neuropathy (AMAN) and acute motor-sensory axonal neuropathy (AMSAN), whereas antibodies to GD1b ganglioside are detected in acute sensory ataxic neuropathy (ASAN). These neuropathies have been proposed to be closely related and comprise a continuous spectrum, although the underlying mechanisms, ...
Known for Sensory Nerves | Nodes Ranvier | Mediated Neuropathies | Ganglioside Antibody
KOL-Index: 12407 . BACKGROUND: Whether or not antiganglioside antibodies are related to axonal or demyelinating Guillain-Barré syndrome (GBS) is still a matter of controversy, as detailed in previous studies conducted in Western and Asian countries. OBJECTIVE: To clarify whether antiganglioside antibodies are associated with axonal dysfunction in Japanese and Italian GBS patient cohorts. METHODS: Clinical ...
Known for Antiganglioside Antibodies | Axonal Guillain | Gbs Japan | Barré Syndrome
KOL-Index: 12237 . Paranodal axo-glial junctions are important for ion channel clustering and rapid action potential propagation in myelinated nerve fibers. Paranode formation depends on the cell adhesion molecules neurofascin (NF) 155 in glia, and a Caspr and contactin heterodimer in axons. We found that antibody to ganglioside GM1 labels paranodal regions. Autoantibodies to the gangliosides GM1 and GD1a ...
Known for Myelinated Nerve Fibers | Paranodal Junctions | Gangliosides Gm1 | Nodes Ranvier
KOL-Index: 11488 . Some patients developed Guillain-Barré syndrome (GBS) after being given bovine gangliosides. Patients with GBS subsequent to Campylobacter jejuni enteritis frequently have IgG antibody to GM1 ganglioside. Miller Fisher syndrome (MFS), a variant of GBS, is associated with IgG antibody to GQ1b ganglioside. The existence of molecular mimicry between GM1 and lipopolysaccharide of C. jejuni ...
Known for Molecular Mimicry | Campylobacter Jejuni | Fisher Syndrome | Patients Gbs
KOL-Index: 11462 . OBJECTIVES: To investigate the pathophysiology of selective absence of F waves and its relation with antiganglioside antibodies in Guillain-Barré syndrome (GBS). Some patients with GBS show the absence of F waves as an isolated conduction abnormality, which has been interpreted as demyelination in the proximal nerve segments. METHODS: In 62 consecutive patients with GBS, sequential nerve ...
Known for Antiganglioside Antibodies | Gbs Patients | Guillainbarré Syndrome | Nerve Conduction
KOL-Index: 11437 . Molecular mimicry between microbial and self-components is postulated as the mechanism that accounts for the antigen and tissue specificity of immune responses in postinfectious autoimmune diseases. Little direct evidence exists, and research in this area has focused principally on T cell-mediated, antipeptide responses, rather than on humoral responses to carbohydrate structures. ...
Known for Carbohydrate Mimicry | Barré Syndrome | Ganglioside Gm1 | Campylobacter Jejuni
KOL-Index: 11433 . Bickerstaff reported eight patients who, in addition to acute ophthalmoplegia and ataxia, showed drowsiness, extensor plantar responses or hemisensory loss. This condition has been named Bickerstaff's brainstem encephalitis (BBE). One patient had gross flaccid weakness in the four limbs. Presumably because of the rarity of this disorder, there has been no reported study on a large number ...
Known for Barré Syndrome | Patients Bbe | Brainstem Encephalitis | Disturbance Consciousness
KOL-Index: 11361 . OBJECTIVES: To identify valuable antiganglioside antibodies that support the diagnosis of Guillain-Barré syndrome (GBS) and its variants in patients showing bulbar palsy as an initial symptom. METHODS: Medical records of 602 patients with GBS or its variants were reviewed. Fifteen patients had bulbar palsy as an initial symptom. Serum antibodies against GM1, GM1b, GD1a, GalNAc-GD1a, GT1a, ...
Known for Bulbar Palsy | Igg Anti | Barré Syndrome | Pcb Gbs

Key People For Barré Syndrome

Top KOLs in the world
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Richard A C Hughes
plasma exchange chronic inflammatory intravenous immunoglobulin
#2
David Reid Cornblath
chronic inflammatory barré syndrome multifocal motor
#3
Pieter Antoon van Doorn
pompe disease chronic inflammatory intravenous immunoglobulin
#4
Nobuhiro Yuki
barré syndrome campylobacter jejuni chronic inflammatory
#5
Bart Casper Jacobs
barré syndrome campylobacter jejuni gbs patients
#6
Arthur K Asbury
axolemmal fraction nerve biopsy genetic testing

Department of Neurology, Tsukuba Hospital, Tsukuba, Ibaraki, Japan | Yuki Clinic, 1-3-7 Johnan, Mito, Ibaraki 310-0803, Japan;, gbs.yuki.cidp@gmail.com | Nobuhiro Yuki is at the Department of Medicine, Eda Memorial Hospital, Azamino-minami 1-1-1, Aob