• Disease
  • Alopecia
  • Alopecia Areata
  • Antonella Tosti

    Prominent publications by Antonella Tosti

    KOL Index score: 13323

    BACKGROUND: Nail invasion by nondermatophytic molds (NDM) is considered uncommon with prevalence rates ranging from 1.45% to 17. 6%.

    OBJECTIVE: We report the clinical features and response to treatment of onychomycosis caused by these molds.

    METHODS: From 1995 through 1998 we performed a mycologic study on 1548 patients affected by nail disorders, and we diagnosed 431 cases of onychomycosis including 59 cases of onychomycosis caused by molds. These include 17 patients with onychomycosis ...

    Also Ranks for: Onychomycosis Caused |  nondermatophytic molds |  fusarium acremonium |  topical treatment |  patients nail
    KOL Index score: 10751

    BACKGROUND: terbinafine persists in the nail at effective concentrations for several weeks after discontinuation of treatment.

    OBJECTIVE: Our purpose was to verify whether intermittent terbinafine therapy is effective in dermatophytic onychomycosis and to compare the results of intermittent terbinafine with those of intermittent itraconazole and continuous terbinafine treatment.

    METHODS: An open, randomized study of 63 patients was performed with three treatment regimens: terbinafine, ...

    Also Ranks for: Intermittent Terbinafine |  itraconazole therapy |  1 week |  nail infections |  drug administration
    KOL Index score: 10011

    OBJECTIVE: To evaluate the benefits of efinaconazole topical solution, 10% on quality of life in onychomycosis patients.

    METHODS: An analysis of 1,655 patients, aged 18 to 70 years, randomized to receive efinaconazole topical solution, 10%, or vehicle from two identical multicenter, double-blind, vehicle-controlled, 48-week studies evaluating safety and efficacy. The primary endpoint was complete cure rate (0% clinical involvement of target toenail, and both negative potassium hydroxide ...

    Also Ranks for: Topical Solution |  efinaconazole 10 |  quality life |  onychomycosis patients |  clinical improvement
    KOL Index score: 9751

    Euxyl K 400 is a preservative for cosmetics and toiletries containing 2 active ingredients, 1,2-dibromo-2,4-dicyanobutan and 2-phenoxyethanol. 2057 consecutive patients with contact dermatitis were patch tested with Euxyl K 400 2.5% pet. and ethanol. A positive patch test occurred in 24 patients (1.2%). The source of sensitization was traced in 8 patients to their cosmetics. Both leave-on and rinse-off products were responsible. Further patch tests with Euxyl K 400 0.5% pet. and ...

    Also Ranks for: Cosmetics Euxyl |  new sensitizer |  contact dermatitis |  cosmetic products |  positive patch test
    KOL Index score: 9679

    BACKGROUND: Clinical efficacy of topical corticosteroids in alopecia areata (AA) is still controversial. Positive clinical results have been obtained using ointments with occlusive dressing but this approach has a low patient compliance. Recently, a new topical formulation (thermophobic foam: Versafoam) of clobetasol propionate 0.05% has been introduced on the market (Olux, Mipharm, Milan, Italy) (CF). This formulation is easy to apply. After application to the skin the foam quickly ...

    Also Ranks for: Clobetasol Propionate |  efficacy safety |  severe aa |  hair regrowth |  12 weeks
    KOL Index score: 9607

    The frequency of positive reactions to 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one (MCI/MI) were studied at 22 European contact dermatitis clinics over a period of 1 year. A total of 4713 patients participated. All the patients were patch tested with nickel sulphate, formaldehyde, paraben-mix, and MCI/MI. 19.4% of the patients had positive patch tests to nickel, making this the most common allergen. 3% of the patients reacted to 100 ppm MCI/MI, while 2.6% ...

    Also Ranks for: Contact Sensitization |  pharmaceutical thiazoles mci |  patch tests |  positive reactions |  facial dermatitis
    KOL Index score: 9528

    Background The entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into type II pneumocytes is dependent on a modification of viral spike proteins by transmembrane protease serine 2 (TMPRSS2) expressed on the surface of human cells. TMPRSS2 is regulated by the androgen receptor, hence, SARS-CoV-2 infectivity is indirectly dependent on androgenic status and phenotype. Previously, we have reported that men affected by androgenetic alopecia (AGA) are overrepresented in ...

    Also Ranks for: Viral Clearance |  clinical remission |  placebo day |  patients proxalutamide |  treatment covid19
    KOL Index score: 9528

    BACKGROUND: Frontal fibrosing alopecia is a variety of cicatricial alopecia characterized by a band of frontal/frontoparietal hair recession and marked decrease or a complete loss of the eyebrows, typically observed in women who are postmenopausal.

    OBJECTIVE: The purpose of this study was to report clinical and histopathologic findings and results of treatment in a group of women affected by the disease.

    METHOD: A total of 14 women with alopecia of the frontal hairline were evaluated ...

    Also Ranks for: Postmenopausal Women |  fibrosing alopecia |  hair follicles |  lichen planopilaris |  selective involvement
    KOL Index score: 9306

    The aim of this study was to verify the most suitable vehicle and concentration for testing Euxyl K 400 and its individual ingredients, and to evaluate the prevalence of sensitization to this preservative over the years in Italy. From January 1991 to October 1994, Euxyl K 2.5% pet. was positive in 99 patients (35 male, 64 female) out of 3455 (2.8%). Of these, 22 out of 855 patients had a positive reaction during 1991 (2.6%), 29 out of 1037 in 1992 (2.8%), 28 out of 858 in 1993 (3.3%), ...

    Also Ranks for: Euxyl Euxyl 400 |  test concentration |  positive reaction |  allergic contact |  sensitization preservative
    KOL Index score: 9197

    This double-blind randomized study was designed to compare the efficacy and safety of calcipotriol ointment (50 microg/g) with betamethasone dipropionate (64 mg/g) and salicylic acid (0.03 g/g) ointment in the treatment of nail bed psoriasis. Fifty-eight patients applied the given drug to the affected nails twice a day for 3-5 months, depending on clinical response. Efficacy was assessed monthly on the basis of nail thickness, measured in millimetres. Photographs of the treated nails ...

    Also Ranks for: Betamethasone Dipropionate |  nail psoriasis |  calcipotriol ointment |  salicylic acid |  months treatment
    KOL Index score: 8831

    BACKGROUND: Onychomycosis is a widespread refractory disease deleteriously affecting quality of life via social stigma and disrupting daily activities. Many physicians perceive onychomycosis as a cosmetic rather than a medical problem.

    OBJECTIVE: Our purpose was to develop a questionnaire-based instrument to quantify the impact of onychomycosis on patients' quality of life.

    METHODS: The questionnaire was developed and validated in a multinational cross-sectional study. Completed ...

    Also Ranks for: Quality Life |  impact onychomycosis |  daily activities |  social stigma |  medical problem
    KOL Index score: 8789

    BACKGROUND: The standard methods used to diagnose scalp and hair disorders (eg, simple clinical inspection, pull test, biopsy) vary in sensitivity, reproducibility, and invasiveness. Studies on a few entities suggest that use of dermoscopy can improve clinical accuracy, but further investigation is needed.

    OBJECTIVES: We sought to: (1) characterize features of several nontumoral scalp and hair conditions using videodermoscopy; and (2) assess the potential usefulness of videodermoscopy in ...

    Also Ranks for: Scalp Disorders |  clinical evaluation |  alopecia areata |  yellow dots |  seborrheic dermatitis
    KOL Index score: 8784

    People commonly inquire about vitamin and mineral supplementation and diet as a means to prevent or manage dermatological diseases and, in particular, hair loss. Answering these queries is frequently challenging, given the enormous and conflicting evidence that exists on this subject. There are several reasons to suspect a role for micronutrients in non-scarring alopecia. Micronutrients are major elements in the normal hair follicle cycle, playing a role in cellular turnover, a frequent ...

    Also Ranks for: Hair Loss |  role vitamins |  nonscarring alopecia |  dermatological diseases |  study relationship
    KOL Index score: 8712

    Cosmetic surgical procedures, including hair transplantation and face-lift surgery, are becoming increasingly popular. However, there is very little information regarding the associated development of dermatological conditions following these procedures. Lichen planopilaris (LPP) is an uncommon inflammatory hair disorder of unknown aetiology that results in permanent alopecia and replacement of hair follicles with scar-like fibrous tissue. Frontal fibrosing alopecia (FFA), a variant of ...

    Also Ranks for: Hair Transplantation |  lichen planopilaris |  ffa lpp |  histological findings |  planus male


    Antonella Tosti: Influence Statistics

    Sample of concepts for which Antonella Tosti is among the top experts in the world.
    Concept World rank
    treated patients rgs #1
    scalp scalp dermatoses #1
    cats patchy alopecia #1
    alopecia role #1
    hair extensions #1
    vivo dermatoscopy #1
    month relapses #1
    hair regrowth treated #1
    skin hypergranulosis #1
    cases nail #1
    central scalp patients #1
    eyebrows trichoscopy #1
    pharmaceutical sensitivity specificity #1
    cases scalp biopsy #1
    nail psoriasis calcipotriol #1
    ffa subtype #1
    treatment alopecias #1
    nail involvement 33 #1
    sources contact dermatitis #1
    nail abnormalities #1
    diffuse alopecia #1
    drugs specific target #1
    finasteride androgenetic alopecia #1
    warts nail unit #1
    subungual epidermoid inclusions #1
    alopecia ffa lpp #1
    complete hair regrowth #1
    control nails #1
    8 clobetasol17propionate #1
    dermoepidermal junction aim #1
    approved therapeutic options #1
    prevalence nail #1
    mesotherapy hyaluronic acid #1
    antifungal agents diagnosis #1
    patients abnormal nails #1
    nail abnormality #1
    d12s1609 #1
    short anagen syndrome #1
    onychopapilloma presenting #1
    1 automatic assessment #1
    frontal accentuation #1
    mediterranean diet diets #1
    flame hairs trichotillomania #1
    inability long hair #1
    treatment rgs #1
    systemic antifungals itraconazole #1
    hair loss cases #1
    onychopapilloma #1
    rcm rcm findings #1
    mesotherapy injection procedures #1

    Key People For Alopecia Areata

    Top KOLs in the world
    Jerry Shapiro
    alopecia areata hair loss lichen planopilaris
    Maria Kramarczuk Hordinsky
    alopecia areata hair loss platelet rich plasma
    Vera H Price
    alopecia areata hair weight topical minoxidil
    Madeleine A Duvic
    mycosis fungoides cell lymphoma alopecia areata
    Kevin John McElwee
    alopecia areata hair follicle c3h hej mice
    Ralf Paus
    hair follicle human skin alopecia areata

    Antonella Tosti:Expert Impact

    Concepts for whichAntonella Tostihas direct influence:Alopecia areata,  Contact dermatitis,  Hair loss,  Androgenetic alopecia,  Allergic contact dermatitis,  Pili annulati,  Nail matrix,  Nail psoriasis.

    Antonella Tosti:KOL impact

    Concepts related to the work of other authors for whichfor which Antonella Tosti has influence:Alopecia areata,  Hair loss,  Contact dermatitis,  Nail psoriasis,  Lichen planus,  Tinea capitis,  Celiac disease.



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    Dr. Philip Frost Department of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA | Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami School of Medicine, Miami, Flori