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    • Elliott D Kozin
    • Elliott D Kozin

      Elliott D Kozin

      Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts | Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts | Department ...



      KOL Resume for Elliott D Kozin


      Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts


      Department of Otolaryngology, Harvard University, Boston, Massachusetts, USA


      Massachusetts Eye and Ear, Boston, Massachusetts

      Otolaryngology, Harvard Medical School, Boston, USA


      Department of Otolaryngology–Head and Neck Surgery, Massachusetts Eye and Ear/Harvard Medical School, Boston, Massachusetts


      Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston


      Department of Otolaryngology and Communication Enhancement, Boston Children's Hospital, Boston, Massachusetts, U.S.A.

      Massachusetts Eye and Ear Infirmary, Harvard Med. School, Eaton-Peabody Lab., 243 Charles St., Boston, MA 02114,


      Department of Otolaryngology–Head and Neck Surgery, Massachusetts Eye and Ear Infirmary, Department of Otology and Laryngology, Harvard Medical School

      Eaton Peabody Laboratories, Massachusetts Eye and Ear Infirmary, Boston, MA, USA

      Otolaryngol., Massachusetts Eye and Ear Infirmary, 243 Charles St., Boston, MA 02114,


      Massachusetts Eye and Ear Infirmary Department of Otolaryngology Boston Massachusetts U.S.A

      Department of Otology and Laryngology, Harvard Medical School;



      Elliott D Kozin: Influence Statistics

      Sample of concepts for which Elliott D Kozin is among the top experts in the world.
      Concept World rank
      endoscopic infracochlear #1
      optogenetic techniques neuroprostheses #1
      postcrisis transition #1
      cholesteatoma outcomes #1
      closure rates outcomes #1
      content brain tumors #1
      surgical simulation laboratory #1
      calculated abg #1
      fascia reconstructed #1
      stapedotomy improve #1
      lowfrequency abg closure #1
      otosclerosis transcanal hrct #1
      138 db conclusion #1
      mid20th centuries #1
      highfrequency abg patients #1
      pilot cadaveric #1
      improve stapedotomy #1
      plane eac #1
      osteotomy otolaryngology #1
      abg calculated #1
      management sensory disorders #1
      outcomes cholesteatoma surgery #1
      children endoscope #1
      814862 #1
      stapedotomy hearing outcomes #1
      thickness pretf #1
      reformat #1
      osteotomy techniques trainees #1
      drum replacement #1
      fascia pretf #1
      persistent frequency abg #1
      covid19 operative practices #1
      consistent wound healing #1
      operative practices otologists #1
      labyrinthine fluid otopathologists #1
      outcomes cholesteatoma #1


      Prominent publications by Elliott D Kozin

      KOL-Index: 12813

      OBJECTIVE: It is generally accepted that patients who require biventricular assist device support have poorer outcomes than those requiring isolated left ventricular assist device support. However, it is unknown how the timing of biventricular assist device insertion affects outcomes. We hypothesized that planned biventricular assist device insertion improves survival compared with delayed conversion of left ventricular assist device support to biventricular assist device ...

      Known for Biventricular Assist | Improved Outcomes | Device Bivad | Early Planned Institution | Failure Heart
      KOL-Index: 9825

      BACKGROUND: More than 200,000 individuals worldwide have received a cochlear implant (CI). Social media Websites may provide a paramedical community for those who possess or are interested in a CI. The utilization patterns of social media by the CI community, however, have not been thoroughly investigated.

      PURPOSE: The purpose of this study was to investigate participation of the CI community in social media Websites.

      RESEARCH DESIGN: We conducted a systematic survey of online CI-related ...

      Known for Social Media | Cochlear Implant | Facebook Groups | Functional Categories | Search Terms
      KOL-Index: 9019

      Small uncontrolled series have suggested that sirolimus favorably impacts renal function after orthotopic liver transplantation (OLT). We sought to retrospectively compare renal dysfunction between cohorts exposed to sirolimus-based and calcineurin inhibitor-based immunosuppression. We retrospectively studied 79 patients converted to sirolimus-based immunosuppression and 100 control subjects continued on calcineurin inhibitor-based immunosuppression after OLT at our institution from 2000 ...

      Known for Renal Dysfunction | Liver Transplantation | Calcineurin Inhibitors | Hepatocellular Carcinoma | Patients Sirolimus
      KOL-Index: 8671

      BACKGROUND: Right ventricular (RV) failure after left ventricular assist device (LVAD) placement is a serious complication and is difficult to predict. In the era of destination therapy and the total artificial heart, predicting post-LVAD RV failure requiring mechanical support is extremely important.

      METHODS: We reviewed patient characteristics, laboratory values and hemodynamic data from 266 patients who underwent LVAD placement at the University of Pennsylvania from April 1995 to June ...

      Known for Ventricular Dysfunction | Assist Device Rvad | Lvad Placement | Mechanical Support | Systolic Blood Pressure
      KOL-Index: 8364

      OBJECTIVE: While hearing loss following temporal bone fracture is a well-described phenomenon, few data exist on auditory dysfunction in patients with traumatic brain injury (TBI) without temporal bone fracture. Herein, we aim to systematically review hearing loss after TBI without bony fracture and describe its etiologies.

      DATA SOURCES: Pubmed, Embase, Cochrane databases.

      REVIEW METHODS: A systematic review of the literature from 1966 to January 2017 was performed using Preferred ...

      Known for Hearing Loss | Traumatic Brain Injury | Temporal Bone Fracture | Exclusion Criteria | Auditory Dysfunction
      KOL-Index: 8141

      Wound healing in the mid-gestation fetus is scarless with minimal inflammation and a unique extracellular matrix. We have previously documented the relative lack of inflammatory cytokines in this environment. We demonstrate that interleukin (IL)-10 is highly expressed in mid-gestation human fetal skin but is absent in postnatal human skin. We hypothesize that overexpression of IL-10 in postnatal skin may replicate a permissive environment for scarless healing. To study the mechanism ...

      Known for Postnatal Wounds | Permissive Environment | Scarless Healing | Scar Formation | Inflammatory Response
      KOL-Index: 7851

      Contemporary auditory brainstem implant (ABI) performance is limited by reliance on electrical neurostimulation with its accompanying channel cross talk and current spread to non-auditory neurons. A new generation ABI based on optogenetic technology may ameliorate limitations fundamental to electrical stimulation. The most widely studied opsin is channelrhodopsin-2 (ChR2); however, its relatively slow kinetic properties may prevent the encoding of auditory information at high stimulation ...

      Known for Chr2 Chronos | Auditory Brainstem | Temporal Resolution | Cochlear Nucleus | Optical Stimulation
      KOL-Index: 7836

      BACKGROUND: COVID-19 has become a global pandemic with a dramatic impact on healthcare systems. Concern for viral transmission necessitates the investigation of otologic procedures that use high-speed drilling instruments, including mastoidectomy, which we hypothesized to be an aerosol-generating procedure.

      METHODS: Mastoidectomy with a high-speed drill was simulated using fresh-frozen cadaveric heads with fluorescein solution injected into the mastoid air cells. Specimens were drilled ...

      Known for Particle Dispersion | Mastoidectomy Relevant | Viral Transmission | Personal Protective Equipment | Aerosolgenerating Procedure
      KOL-Index: 7798

      OBJECTIVES/HYPOTHESIS: Only a few reports describe the outcomes following endoscopic ear surgery (EES) in children for chronic ear disease. We differentiate between transcanal endoscopic ear surgery (TEES), where the case is performed with only endoscopic visualization, from non-TEES, where the endoscope is not used at all or used as an adjunct to the microscope. We hypothesize that EES is an effective approach to manage middle ear pathology using a transcanal approach in most cases, and ...

      Known for Endoscopic Ear | Preschool Cholesteatoma | Tees Children | Transcanal Approach | Surgical Procedures
      KOL-Index: 7722

      The tympanic membrane (TM) is an exquisite structure that captures and transmits sound from the environment to the ossicular chain of the middle ear. The creation of TM grafts by multi-material three-dimensional (3D) printing may overcome limitations of current graft materials, e.g. temporalis muscle fascia, used for surgical reconstruction of the TM. TM graft scaffolds with either 8 or 16 circumferential and radial filament arrangements were fabricated by 3D printing of ...

      Known for Tympanic Membrane | Temporalis Fascia | Printed Grafts | Mechanical Properties | Design Fabrication
      KOL-Index: 7478

      OBJECTIVE: Outcomes of the supraclavicular artery island flap (SCAIF) have not been extensively studied in comparison with free tissue transfer (FTT) flaps for head and neck reconstruction. We hypothesize that the pedicled SCAIF has decreased operating room time, length of stay, time to wound healing of recipient site, complications, and hospital charges as compared with FTT.

      STUDY DESIGN: Case series with chart review.

      SETTING: Tertiary care teaching hospital.


      Known for Scaif Ftt | Free Flap | Supraclavicular Artery | Recipient Site | Chart Review
      KOL-Index: 7000

      OBJECTIVES/HYPOTHESIS: Although the theoretical risk of elevated temperatures during endoscopic ear surgery has been reported previously, neither temperature change nor heat distribution associated with the endoscope has been quantified. In this study, we measure temperature changes during rigid middle ear endoscopy in a human temporal bone model and investigate whether suction can act as a significant cooling mechanism.

      STUDY DESIGN: Human temporal bone model of endoscopic middle ear ...

      Known for Ear Surgery | Temporal Bone | Light Source | Elevated Temperatures | Endoscopic Middle
      KOL-Index: 6984

      IMPORTANCE: Smiling can be a voluntary or involuntary movement. Facial reanimation procedures differ in their ability to restore a spontaneous smile, and an assay designed to evoke and evaluate a spontaneous smile is not available.

      OBJECTIVE: To develop and validate an assay to assess the spontaneous smile of patients with facial paralysis.

      DESIGN, SETTING, AND PARTICIPANTS: This was an exploratory cohort study. A series of short video clips were administered to laypersons via an online ...

      Known for Spontaneous Smile | Facial Paralysis | Oral Commissure | 1 2014 | Aged Smiling
      KOL-Index: 6810

      Base excision repair (BER) of damaged deoxyribonucleic acid (DNA) is a multistep process during which potentially lethal abasic sites temporarily exist. Repair of these lesions is greatly stimulated by heat shock protein 70 (Hsp70), which enhances strand incision and removal of the abasic sites by human apurinic-apyrimidinic endonuclease (HAP1). The resulting single-strand gaps must then be filled in. Here, we show that Hsp70 and its 48- and 43-kDa N-terminal domains greatly stimulated ...

      Known for Heat Shock Protein | Dna Repair | Base Excision | Polymerase Beta | Deoxyribonucleic Acid
      KOL-Index: 6765

      OBJECTIVE: The auditory brainstem implant (ABI) was initially developed for patients with deafness as a result of neurofibromatosis type 2. ABI indications have recently extended to children with congenital deafness who are not cochlear implant candidates. Few multi-institutional outcome data exist. Herein, we aim to provide a systematic review of outcomes following implantation of the ABI in pediatric patients with nontumor diagnosis, with a focus on audiometric outcomes.

      DATA SOURCES: ...

      Known for Auditory Brainstem | Implant Outcomes | Pediatric Patients | Congenital Deafness | Neurofibromatosis Type

      Key People For Hearing Loss

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      Elliott D Kozin:Expert Impact

      Concepts for whichElliott D Kozinhas direct influence:Hearing loss,  Temporal bone,  Head injury,  Cochlear implantation,  Endoscopic ear surgery,  Ear surgery,  Superior canal dehiscence,  Endoscopic ear.

      Elliott D Kozin:KOL impact

      Concepts related to the work of other authors for whichfor which Elliott D Kozin has influence:Ventricular failure,  Secretory carcinoma,  Assist device,  Ear surgery,  Lvad implantation,  Wound healing,  Tympanic membrane.



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      Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts | Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts | Department of Otolaryngology, Massachusetts Eye and Ear | Department of Otolaryngology,

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