 | David C NaftelKirklin Institute for Research in Surgical Outcomes, University of Alabama at Birmingham, Birmingham, Ala. | Kirklin Institute for Research in Surgical Outcomes, University of ... |
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David C Naftel:Expert Impact
Concepts for whichDavid C Naftelhas direct influence:Heart transplantation,Heart transplant,Cardiac transplantation,United states,Interagency registry,Pediatric heart,Late rejection,Risk factors death.
David C Naftel:KOL impact
Concepts related to the work of other authors for whichfor which David C Naftel has influence:Heart transplantation,Ventricular assist,Marfan syndrome,Mechanical circulatory support,Aortic valve,Cardiopulmonary bypass,Lvad implantation.
KOL Resume for David C Naftel
| Year | |
|---|---|
| 2021 | Kirklin Institute for Research in Surgical Outcomes, University of Alabama at Birmingham, Birmingham, Ala. |
| 2020 | Kirklin Institute for Research in Surgical Outcomes, University of Alabama, Birmingham, Alabama. |
| 2019 | University of Alabama at Birmingham, Birmingham, AL |
| 2018 | Department of Surgery, University of Alabama at Birmingham, Birmingham, AL |
| 2017 | Kirklin Institute for Research in Surgical Outcomes University of Alabama at Birmingham BirminghamAL USA Cardiovascular Thoracic Surgery Research, The University of Alabama at Birmingham, Birmingham, AL Division of Cardiothoracic Surgery, Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama |
| 2016 | Division of Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, Alabama |
| 2015 | From the Division of Cardiovascular Diseases, Department of Medicine (R.Y.L.-R., D.A., S.V.P., J.A.T.), Division of Cardiothoracic Surgery, Department of Surgery (R.C.), and Department of Epidemiology, School of Public Health (R.C.), and Division of Cardiothoracic Surgery (D.N., J.K.), University of Alabama at Birmingham; and Section of Heart Failure, Department of Medicine, Cleveland Clinic Foundation, OH (R.C.S.). Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama. Cardiovascular Division, University of Alabama at Birmingham, Birmingham, Alabama |
| 2014 | Cardiovascular Surgery Research, University of Alabama at Birmingham, Alabama Department of Pathology, Thomas E Starzl Transplant Institute |
| 2013 | Connie White-Williams, PhD, RN, FAAN Assistant Professor, School of Nursing, Department of Nursing, Center for Nursing Excellence, University of Alabama at Birmingham. Kathleen L. Grady, PhD, RN, APN, FAAN Associate Professor, Feinberg School of Medicine, Department of Surgery, Northwestern University, and Administrative Director, Center for Heart Failure of the Bluhm Cardiovascular Institute, Northwestern Memorial Hospital, Chicago, Illinois. Susan Myers, BBA Database Administrator, Division of Cardiothoracic Surgery, University of Alabama Medical Center, Birmingham. David C. Naftel, PhD Professor of Surgery and Professor of Biostatistics, Division of Cardiothoracic Surgery, University of Alabama at Birmingham. Edward Wang, PhD Research Associate Professor, Department of Surgery, and Director of Biostatistics Core, Comprehensive Transplantation Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois. Robert C. Bourge, MD Professor of Medicine, Radiology, and Surgery, Division of Cardiology, University of Alabama at Birmingham. Bruce Rybarczyk, PhD, ABPP Associate Professor and Director of Training, Clinical Psychology Program, Department of Psychology, Virginia Commonwealth University, Richmond. Department of Cardiothoracic Surgery, University of Alabama Medical Center, Birmingham, Alabama |
| 2012 | Department of Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, Alabama |
| 2011 | Medicine/Surgery, University of Alabama at Birmingham, Birmingham, AL Department of Surgery, Division of Cardiothoracic Surgery, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama |
| 2010 | University of Alabama School of Medicine, Birmingham, AL, USA |
| 2009 | University of Alabama, Birmingham, Birmingham, AL |
| 2008 | Department of Surgery University of Alabama at Birmingham, Birmingham, Alabama |
| 2007 | University of Alabama Medical Center, Birmingham, Alabama |
| 2006 | *Division of Nephrology, Department of Medicine, †Division of Transplantation, Department of Surgery, and ‡Division of Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, Alabama |
| 2005 | University of Alabama, Birmingham, Alabama Pediatric Cardiology, St. Louis Children’s Hospital, St. Louis, MO International Society for Heart and Lung Transplantation, Addison, Texas. |
| 2004 | Division of Cardiothoracic Surgery, University of Alabama, Birmingham, Alabama, USA Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, AL, UK |
| 2003 | From Northwestern University; Harvard University; University of Pittsburgh; and University of Alabama at Birmingham. Division of Cardiovascular and Thoracic Surgery, The University of Alabama at Birmingham, Birmingham, AL, USA |
| 2002 | Department of Surgery, Birmingham, Alabama, USA |
| 2001 | Cardiac Transplant Research Database, University of Alabama at Birmingham, Birmingham, AL, USA |
| 2000 | Grunkemeier, Li: Medical Data Research Center, Providence Health System, Portland, Oregon Division of Cardiovascular Surgery, Department of Surgery, The University of Alabama at Birmingham, Birmingham, AL, USA |
| Concept | World rank |
|---|---|
| fetal listing htx | #1 |
| outcome listing | #1 |
| higherrisk repair | #1 |
| objective performance criteria | #1 |
| n965 | #1 |
| multiinstitutional study background | #1 |
| events rejection | #1 |
| preschool databases spa | #1 |
| higher education predictors | #1 |
| 5 wu | #1 |
| amr 88 | #1 |
| mortality heart transplant | #1 |
| phts subjects | #1 |
| association elevated pvri | #1 |
| 35 participating centers | #1 |
| multivariable equations | #1 |
| devices adverse | #1 |
| identified recipient | #1 |
| incidence tx | #1 |
| prps vasculopathy | #1 |
| survival listing | #1 |
| intermacs data | #1 |
| preoperative meld scores | #1 |
| pvod transplant | #1 |
| 5 years transplant | #1 |
| pvri chd | #1 |
| ht stressor scale | #1 |
| posthtx outcomes | #1 |
| ht rejection episodes | #1 |
| year black race | #1 |
| survival allosensitization | #1 |
| im1 shock | #1 |
| association pvri | #1 |
| dose inotropes | #1 |
| ongoing public discourse | #1 |
| competing outcomes analysis | #1 |
| 1 year waitlist | #1 |
| ht higher education | #1 |
| outcomes treated amr | #1 |
| closure repair | #1 |
| 59 227 pg | #1 |
| 97 10 years | #1 |
| cardiac transplantation children | #1 |
| death waiting | #1 |
| pediatric recipients transplants | #1 |
| tube congenital humans | #1 |
| list infants | #1 |
| enteropathy heart | #1 |
| perfect fontan | #1 |
| operative mortality subjects | #1 |
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Prominent publications by David C Naftel
Balancing rejection and infection with respect to age, race, and gender: Clues acquired from 17 years of cardiac transplantation data
[ PUBLICATION ]
BACKGROUND: Donor and recipient risk factors for rejection and infection have been well characterized. The contribution of demographic factors, especially age at the time of transplantation to morbidity and mortality due to rejection and infection, is much less well understood.
METHODS: Using parametric hazard analysis and multivariate risk-factor equations for infection and rejection events, we quantitatively determined the relationship of fundamental demographic variables (age, race ...
| Known for Infection Rejection | Age Time | Transplantation Data | Race Gender | 30 Years |
BACKGROUND: Use of mechanical circulatory support in children has increased as more options have become available. A national account of the use of mechanical support in children and adolescents is essential to understanding outcomes, refining patient selection and improving quality of care.
METHODS: The Pediatric Interagency Registry for Mechanical Circulatory Support (PediMACS) is a National Heart, Lung, and Blood Institute-supported nationwide registry for temporary and durable ...
| Known for Assist Device | Interagency Registry | Circulatory Support | Outcomes Children | Pediatric Patients |
Minimizing infection and rejection death: Clues acquired from 19 years of multi-institutional cardiac transplantation data
[ PUBLICATION ]
BACKGROUND: The purpose of this study was to estimate the relationship of age, race and gender to rejection and infection across time with respect to age at time of transplant, year of transplantation and immunosuppressive era.
METHODS: The study group consisted of 10,131 patients from 29 institutions in the Cardiac Transplant Research Database (n = 7,368, from 1990 to 2008) and 32 institutions in the Pediatric Heart Transplant Study (n = 2,763, from 1993 to 2008). The probabilities of ...
| Known for Rejection Infection | 19 Years | Risk Factors Death | Age Transplant | Continental Ancestry |
BACKGROUND: Beginning in 2000 and accelerating in 2004, the Berlin Heart EXCOR (Berlin Heart Inc Woodlands, TX) became the first pediatric-specific ventricular assist device (VAD) applied throughout North America for children of all sizes. This retrospective study analyzed the initial Berlin Heart EXCOR pediatric experience as a bridge to transplantation.
METHODS: Between June 2000 and May 2007, 97 EXCOR VADs were implanted in North America at 29 different institutions. The analysis is ...
| Known for Berlin Heart | Cardiac Transplantation | North America | Assist Device | Dilated Child Child |
Late rejection episodes more than 1 year after pediatric heart transplantation: risk factors and outcomes
[ PUBLICATION ]
BACKGROUND: Little is known about late rejection episodes after pediatric heart transplantation. We determined the frequency of late rejection episodes (>1 year) after pediatric heart transplantation, defined risk factors for its occurrence, and evaluated outcome after late rejection.
METHODS: We analyzed data from 685 pediatric recipients (<18 years at transplantation) who underwent transplantation between January 1, 1993, and December 31, 1997, at 18 centers in the Pediatric Heart ...
| Known for Late Rejection | 1 Year | Pediatric Heart | Transplantation Risk | Severe Hemodynamic Compromise |
BACKGROUND: Pump thrombosis remains an uncommon but potentially catastrophic complication of durable continuous-flow left ventricular assist devices (LVAD). A perceived increase in the incidence of pump thrombosis in the HeartMate II (HMII) LVAD (Thoratec, Pleasanton, CA) by clinicians prompted this analysis of the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) database.
METHODS: Between 2006 and June 2013, 8,988 United States patients aged older than 18 ...
| Known for Pump Thrombosis | Interagency Registry | Ventricular Assist Device | 1 Year | Circulatory Support |
BACKGROUND: Patients requiring biventricular assist device (BiVAD) for mechanical circulatory support (MCS) have substantially worse outcomes than patients requiring left VAD (LVAD) support only. Patient-specific risk factors have yet to be consistently identified in a large, multicenter registry, which may underlie the poorer outcomes for BiVAD patients. The Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) is a registry of U.S. Food and Drug ...
| Known for Interagency Registry | Assist Device | Bivad Patients | Circulatory Support | United States |
BACKGROUND: The relationship between pre-transplant body weight and post-transplant outcome has only recently been identified using a single, indirect measure of weight (percent ideal body weight [PIBW]). The literature is equivocal regarding which index is the better indicator of body weight. The purpose of this study was to determine (1) if pre-heart transplant body weight, measured by body mass index (BMI) and PIBW, is associated with post-heart transplant morbidity and mortality and ...
| Known for Heart Transplant | Pibw Bmi | Infection Patients | Preoperative Obesity | Retrospective Studies |
OBJECTIVES: The present study compared the interval until device exchange or death from pump-related failure in patients with pulsatile versus continuous flow left ventricular assist devices.
METHODS: Data from Interagency Registry for Mechanically Assisted Circulatory Support (June 23, 2006, to March 31, 2011) compared the durability of implanted pulsatile and continuous flow left ventricular assist devices. The durability issues included pump replacement for infection, ...
| Known for Ventricular Assist Devices | Interagency Registry | Continuous Flow | Circulatory Support | Mechanically Assisted |
Despite improvement in surgical and medical management of children with congenital and acquired heart disease, cardiac transplantation remains an important therapeutic option for infants and children with end-stage heart disease. Ultimate survival in patients who are listed for transplantation is a function of both mortality while awaiting transplantation and survival after transplantation. Survival of heart transplantation is affected by the severity of illness before transplantation, ...
| Known for Survival Transplantation | Older Children | Risk Factors Death | 1 Year | 6 Months |
Analysis and predictors of pulmonary vascular resistance after cardiac transplantation
[ PUBLICATION ]
Elevated pulmonary vascular resistance is a known risk factor for early death from acute right ventricular failure after orthotopic cardiac transplantation. Patients in whom the elevated pulmonary vascular resistance is due primarily to increased left atrial pressure ("reactive") frequently have normalization of resistance after transplantation, but few studies have detailed the time course and magnitude of these changes. To analyze the response of pulmonary vascular resistance to ...
| Known for Pulmonary Vascular | Cardiac Transplantation | Mm Hg | Early Death | 182 Patients |
The Effect of Age, Diagnosis, and Previous Surgery in Children and Adults Undergoing Heart Transplantation for Congenital Heart Disease
[ PUBLICATION ]
OBJECTIVES: We sought to evaluate the outcomes and identify risk factors for mortality after heart transplantation (HT) for congenital heart disease (CHD) in infants, children, and adults.
BACKGROUND: CHD is considered a risk factor for mortality after HT, yet this unique group of patients represents a spectrum of complexity.
METHODS: There were 488 patients transplanted for CHD from the combined Pediatric Heart Transplant Study (1993 to 2002, n = 367) and the Cardiac Transplant Registry ...
| Known for Heart Transplantation | Children Adults | Great Arteries | Ht Survival | Risk Factors Mortality |
