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    • Heart Transplantation
    • James K Kirklin
    • James K Kirklin: Influence Statistics

      James K Kirklin

      James K Kirklin

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      Kirklin Institute for Research in Surgical Outcomes, Birmingham, AL | Kirklin Institute for Research in Surgical Outcomes, University of Alabama, Birmingham, Alabama, USA | ...

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      James K Kirklin:Expert Impact

      Concepts for whichJames K Kirklinhas direct influence:Heart transplantation,Heart transplant,Cardiac transplantation,Heart failure,Ventricular assist,United states,Ventricular assist devices,Interagency registry.

      James K Kirklin:KOL impact

      Concepts related to the work of other authors for whichfor which James K Kirklin has influence:Heart transplantation,Cardiopulmonary bypass,Ventricular assist,Cardiac surgery,Mechanical circulatory support,Cardiogenic shock,Coronary artery.

      KOL Resume for James K Kirklin

      Year
      2022

      Kirklin Institute for Research in Surgical Outcomes, Birmingham, AL

      Division of Cardiothoracic Surgery, Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama

      2021

      Kirklin Institute for Research in Surgical Outcomes (KIRSO), The University of Alabama at Birmingham, Birmingham AL

      Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama

      2020

      Univ of Alabama at Birmingham, AL

      Kirklin Institute for Research in Surgical Outcomes, Birmingham, Alabama, US

      2019

      James and John Kirklin Institute for Research in Surgical Outcomes (KIRSO), University of Alabama, Birmingham, Alabama.

      Department of Surgery, The University of Alabama at Birmingham, Birmingham, AL, USA

      Division of Cardiothoracic Surgery, University of Alabama Birmingham, Birmingham, AL

      Kirklin Institute for Research in Surgical Outcomes, Birmingham, Alabama

      2018

      Cardiothoracic Surgery, The University of Alabama at Birmingham, AL.

      University of Alabama at Birmingham, Birmingham, AL

      Division of Congenital Heart Surgery, Baylor College of Medicine, Houston, TX, US.

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      Sample of concepts for which James K Kirklin is among the top experts in the world.
      Concept World rank
      annual pediatric #1
      prothrombin corm2 #1
      patients 1 strokes #1
      pediatric htx time #1
      lrhf mortality #1
      photopheresis therapy photo #1
      pci acd #1
      centers methods #1
      length function shock #1
      increased risk implantation #1
      survival rhf #1
      kcorrection scale #1
      highdose inotropes #1
      thrombelastographic measures #1
      closure replacement #1
      transplant age #1
      epde5i lrhf #1
      transplant fontan patients #1
      infusion beige spc #1
      intermacs analysis #1
      rejection lower risk #1
      cardiomyopathy 5 survival #1
      lvad implantation features #1
      cav statin #1
      ht infant rsbmsr #1
      dcm patients transplant #1
      areas qol #1
      pda ligation development #1
      globulin okt3 #1
      purpose tli #1
      mcs achd patients #1
      btt isp #1
      young hypoplastic #1
      cta 14 patients #1
      hrqol implant strategy #1
      early infections okt3 #1
      heparininduced thrombocytopenia dtis #1
      stroke risk infection #1
      pda prophylactic ligation #1
      versus predicted survival #1
      received mechanical #1
      thoracotomy implants length #1
      continued support exchange #1
      bidirectional glenn fontan #1
      cardiomyopathy chd #1
      myxomas hemangioma #1
      ductus babies #1
      fontan procedure survival #1
      transplant fontan #1
      year pediatric #1
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      Prominent publications by James K Kirklin

      KOL-Index: 18296

      BACKGROUND: Donor and recipient risk factors for rejection and infection have been well characterized. The contribution of demographic factors, especially age at the time of transplantation to morbidity and mortality due to rejection and infection, is much less well understood.

      METHODS: Using parametric hazard analysis and multivariate risk-factor equations for infection and rejection events, we quantitatively determined the relationship of fundamental demographic variables (age, race ...

      Known for Infection Rejection | Age Time | Transplantation Data | Race Gender | 30 Years
      KOL-Index: 16655

      BACKGROUND: Use of mechanical circulatory support in children has increased as more options have become available. A national account of the use of mechanical support in children and adolescents is essential to understanding outcomes, refining patient selection and improving quality of care.

      METHODS: The Pediatric Interagency Registry for Mechanical Circulatory Support (PediMACS) is a National Heart, Lung, and Blood Institute-supported nationwide registry for temporary and durable ...

      Known for Assist Device | Interagency Registry | Circulatory Support | Outcomes Children | Pediatric Patients
      KOL-Index: 15923

      BACKGROUND: The purpose of this study was to estimate the relationship of age, race and gender to rejection and infection across time with respect to age at time of transplant, year of transplantation and immunosuppressive era.

      METHODS: The study group consisted of 10,131 patients from 29 institutions in the Cardiac Transplant Research Database (n = 7,368, from 1990 to 2008) and 32 institutions in the Pediatric Heart Transplant Study (n = 2,763, from 1993 to 2008). The probabilities of ...

      Known for Rejection Infection | 19 Years | Risk Factors Death | Age Transplant | Continental Ancestry
      KOL-Index: 15343

      BACKGROUND: Little is known about late rejection episodes after pediatric heart transplantation. We determined the frequency of late rejection episodes (>1 year) after pediatric heart transplantation, defined risk factors for its occurrence, and evaluated outcome after late rejection.

      METHODS: We analyzed data from 685 pediatric recipients (<18 years at transplantation) who underwent transplantation between January 1, 1993, and December 31, 1997, at 18 centers in the Pediatric Heart ...

      Known for Late Rejection | 1 Year | Pediatric Heart | Transplantation Risk | Severe Hemodynamic Compromise
      KOL-Index: 15013

      BACKGROUND: The Interagency Registry for Mechanically Assisted Circulatory Support (Intermacs), a joint effort among the National Heart, Lung, and Blood Institute, the Food and Drug Administration, the Centers for Medicare and Medicaid Services, and others, was established in 2005 at the University of Alabama at Birmingham. The registry examined clinical outcomes and quality-of-life metrics of patients who received an Food and Drug Administration-approved durable mechanical circulatory ...

      Known for Patients Lvads | Lvad Support | 1 Year | Destination Therapy | Thoracic Surgeons
      KOL-Index: 14607

      BACKGROUND: Pump thrombosis remains an uncommon but potentially catastrophic complication of durable continuous-flow left ventricular assist devices (LVAD). A perceived increase in the incidence of pump thrombosis in the HeartMate II (HMII) LVAD (Thoratec, Pleasanton, CA) by clinicians prompted this analysis of the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) database.

      METHODS: Between 2006 and June 2013, 8,988 United States patients aged older than 18 ...

      Known for Pump Thrombosis | Interagency Registry | Ventricular Assist Device | 1 Year | Circulatory Support
      KOL-Index: 14051

      BACKGROUND: Patients requiring biventricular assist device (BiVAD) for mechanical circulatory support (MCS) have substantially worse outcomes than patients requiring left VAD (LVAD) support only. Patient-specific risk factors have yet to be consistently identified in a large, multicenter registry, which may underlie the poorer outcomes for BiVAD patients. The Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) is a registry of U.S. Food and Drug ...

      Known for Interagency Registry | Assist Device | Bivad Patients | Circulatory Support | United States
      KOL-Index: 14029

      BACKGROUND: The relationship between pre-transplant body weight and post-transplant outcome has only recently been identified using a single, indirect measure of weight (percent ideal body weight [PIBW]). The literature is equivocal regarding which index is the better indicator of body weight. The purpose of this study was to determine (1) if pre-heart transplant body weight, measured by body mass index (BMI) and PIBW, is associated with post-heart transplant morbidity and mortality and ...

      Known for Heart Transplant | Pibw Bmi | Infection Patients | Preoperative Obesity | Retrospective Studies
      KOL-Index: 13869

      OBJECTIVE: The study objective was to evaluate in a prospective, randomized, multicenter trial the safety and efficacy of mitral valve surgery with and without the CorCap cardiac support device (Acorn Cardiovascular, St Paul, Minn) in patients with New York Heart Association Class II to IV heart failure.

      BACKGROUND: Although mitral valve surgery has been performed successfully in patients with heart failure, the safety and long-term efficacy have not been established in a multicenter ...

      Known for Mitral Valve Surgery | Heart Failure | Acorn Clinical Trial | Quality Life | Cardiac Support
      KOL-Index: 13607

      OBJECTIVES: The present study compared the interval until device exchange or death from pump-related failure in patients with pulsatile versus continuous flow left ventricular assist devices.

      METHODS: Data from Interagency Registry for Mechanically Assisted Circulatory Support (June 23, 2006, to March 31, 2011) compared the durability of implanted pulsatile and continuous flow left ventricular assist devices. The durability issues included pump replacement for infection, ...

      Known for Ventricular Assist Devices | Interagency Registry | Continuous Flow | Circulatory Support | Mechanically Assisted
      KOL-Index: 13606

      BACKGROUND: The Interagency Registry for Mechanically Assisted Circulatory Support (Intermacs), a joint effort among the National Heart, Lung, and Blood Institute, the Food and Drug Administration, the Centers for Medicare and Medicaid Services, and others, was established in 2005 at the University of Alabama at Birmingham. The registry examined clinical outcomes and quality-of-life metrics of patients who received an Food and Drug Administration-approved durable mechanical circulatory ...

      Known for Patients Lvads | Lvad Support | 1 Year | Thoracic Surgeons Intermacs | Destination Therapy
      KOL-Index: 13161

      Elevated pulmonary vascular resistance is a known risk factor for early death from acute right ventricular failure after orthotopic cardiac transplantation. Patients in whom the elevated pulmonary vascular resistance is due primarily to increased left atrial pressure ("reactive") frequently have normalization of resistance after transplantation, but few studies have detailed the time course and magnitude of these changes. To analyze the response of pulmonary vascular resistance to ...

      Known for Pulmonary Vascular | Cardiac Transplantation | Mm Hg | Early Death | 182 Patients

      Key People For Heart Transplantation

      Top KOLs in the world
      #1
      Jon A Kobashigawa
      heart transplantation united states mycophenolate mofetil
      #2
      Leah Bennett Edwards
      lung transplantation international society united states
      #3
      James K Kirklin
      heart transplantation ventricular assist united states
      #4
      Donna M Mancini
      heart failure cardiac transplantation ventricular assist
      #5
      Josef Stehlik
      lung transplantation heart failure international society
      #6
      David C Naftel
      heart transplantation united states interagency registry

      Kirklin Institute for Research in Surgical Outcomes, Birmingham, AL | Kirklin Institute for Research in Surgical Outcomes, University of Alabama, Birmingham, Alabama, USA | Division of Cardiothoracic Surgery, Kirklin Institute for Research in Surgica

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