• KOL
    • Heat Urticaria
    • Combination Of Localized...
    • Combination of localized heat urticaria and cold urticaria. Release of histamine in suction blisters and successful treatment of heat urticaria with doxepin: Influence Statistics

      Expert Impact

      Concepts for whichthey havehas direct influence:Heat urticaria,Cold urticaria,Localized heat urticaria,Localized heat,Patients doxepin,Female histamine,Cold temperature,Hot temperature.

      Key People For Heat Urticaria

      Top KOLs in the world
      #1
      Malcolm Watson Greaves
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      #2
      John Andrew Grant
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      #3
      David O Thueson
      histamine release human basophils lactic acid
      #4
      Gerald G Krueger
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      #5
      Steven R Findlay
      histamine release complement activation polistes wasp hypersensitivity
      #6
      Douglas P Fine
      complement activation histamine release meningococcal meningitis

      Combination of localized heat urticaria and cold urticaria. Release of histamine in suction blisters and successful treatment of heat urticaria with doxepin

      Abstract

      Two female patients with a rare combination of localized heat urticaria and cold urticaria are described. One patient had localized heat urticaria combined with delayed cold urticaria and the other patient had localized heat urticaria in combination with idiopathic (primary acquired) cold urticaria. Increased histamine concentration was measured in suction blister fluid samples collected immediately after the heal challenge in both patients. Doxepin effectively suppressed the whealing response on the heat challenged skin. These results suggest that histamine is the main mediator in heat urticaria reactions.

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