• KOL
    • Hepatic Encephalopathy
    • Juan Córdoba
    • Juan Córdoba: Influence Statistics

      Juan Córdoba

      Juan Córdoba

      Liver Unit, Department of Internal Medicine, Hospital Universitari Vall d'Hebron, VHIR, Universitat Autònoma de Barcelona, CIBERehd, Barcelona, Spain. | Liver Unit, Department ...

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      Juan Córdoba:Expert Impact

      Concepts for whichJuan Córdobahas direct influence:Hepatic encephalopathy,Liver transplantation,Brain edema,Patients cirrhosis,Portacaval anastomosis,Liver failure,Chronic hepatitis,Magnetic resonance.

      Juan Córdoba:KOL impact

      Concepts related to the work of other authors for whichfor which Juan Córdoba has influence:Hepatic encephalopathy,Liver transplantation,Cirrhotic patients,Decompensated cirrhosis,Chronic hepatitis,Portal hypertension,Bacterial infections.

      KOL Resume for Juan Córdoba

      Year
      2020

      Liver Unit, Department of Internal Medicine, Hospital Universitari Vall d'Hebron, VHIR, Universitat Autònoma de Barcelona, CIBERehd, Barcelona, Spain.

      2018

      Liver Unit, Department of Internal Medicine, Hospital Universitari Vall d´Hebron, VHIR, Universitat Autònoma de Barcelona, CIBERehd, Barcelona, Spain

      2017

      Liver Unit, Department of Internal Medicine, Hospital Universitari Vall d’Hebron, VHIR, Universitat Autònoma de Barcelona, CIBERehd, Barcelona, Spain

      2016

      Liver Unit, Hospital Universitari Vall d’Hebron, Vall d’Hebron Institute of Research and Department of Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain CIBERehd, Instituto de Salud Carlos III, Madrid, Spain

      2015

      Universitat Autònoma de Barcelona, Bellaterra (Cerdanyola del Vallès), Spain

      Servicio de Microbiología, Hospital Universitari i Politècnic La Fe, Valencia, España

      2014

      CIBEREHD, Instituto de Salud Carlos III, Madrid, España

      Universitat Autònoma de Barcelona Departament de Medicina Cerdanyola del Vallès Spain

      2013

      Department of Medicine, Universitat Autònoma de Barcelona, CIBEREHD, Instituto de Salud Carlos III, Madrid, Spain

      2012

      Servei de Medicina Interna-Hepatologia, Hospital Vall d’Hebron, Pg. Vall d’Hebron 119-129, 08035, Barcelona, Spain

      2011

      Servei de Medicina Interna-Hepatologia, Hospital Vall d’Hebron. Barcelona, Spain

      2010

      Servei de Medicina Interna-Hepatologia, Hospital Universitari Vall d'Hebron, Barcelona, Spain., Departament de Medicina, Universitat Autònoma de Barcelona, Barcelona, Spain., Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III, Madrid, Spain.,

      Hospital Universitari Vall d'Hebron, Paseig Vall d'Hebron 119‐129, 08035 Barcelona. Spain

      2009

      Departament Medicina, Universitat Autònoma de Barcelona, Barcelona, Spain

      Department of Medicine, Northwestern University Medical School, Chicago, Illinois, USA

      2008

      Asociación Española para el Estudio del Hígado. Escuela Andaluza de Salud Pública. Granada. España

      Centro de Investigación Biomédica en Red Enfermedades Hepáticas y Digestivas (CIBEREHD), Spain

      2007

      Departament de Medicina. Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Spain

      2006

      Servei de Medicina Interna‐Hepatologia, Hospital Universitari Vall d'Hebron, Pg. Vall d'Hebron 119, Barcelona 08035, Spain

      Unidad de Hepatología. Servicio de Medicina Interna. Hospital Vall d’Hebron. Barcelona. España

      2005

      Liver Unit, Hospital Universitari Vall d'Hebron, Barcelona, Spain

      2004

      Servei de Medicina Interna‐Hepatologia, Hospital Vall d'Hebron, Passeig Vall d'Hebron 119, Barcelona 08035, Spain

      2003

      Servei de Medicina Interna‐Hepatologia, Universitat Autònoma de Barcelona, Barcelona, Spain

      2002

      Liver Unit, Hospital Universitari Vall d'Hebron, Paseo Vall d'Hebron 119, Barcelona 08035, Spain

      Servicio de Microbiología. Hospital Universitario La Fe. Valencia

      2001

      Microbiology, Valencia, Spain

      2000

      Department of Microbiología, Hospital Universitario La FE, Valencia, Spain

      1999

      Department of Medicine, Veterans Administration Lakeside Medical Center and Northwestern University, Chicago, Illinois

      Microbiology Service, and Hospital Universitario La Fe, Valencia, Spain

      Sign-in to see all concepts, it's free!
      Sample of concepts for which Juan Córdoba is among the top experts in the world.
      Concept World rank
      encefalopatía hepática #1
      ammonia genesis #1
      3 disturbances #1
      portacaval anastomosis vivo #1
      hepatic encephalopathy eh #1
      tstudent pearson correlation #1
      minimal eh #1
      episode encephalopathy #1
      portacaval anastomosis model #1
      mild hypothermia model #1
      liverinduced inflammation #1
      decompensated cirrhosis decrease #1
      mep disturbances #1
      drug‐induced removal #1
      long term neuroimaging #1
      episodic hepatic encephalopathy #1
      dst sdt #1
      disturbances rats #1
      liver disease rats #1
      valid method models #1
      cirrhosis general measures #1
      upgo time #1
      cirrhotic decompensated #1
      hyponatremia model #1
      life encephalopathy hepatitis #1
      safety ornithine #1
      brain vasodilation #1
      encephalopathy eh #1
      overt eh complexity #1
      safety ornithine phenylacetate #1
      inflammation hurts #1
      encephalopathy portal #1
      episodic hepatic #1
      2 chronic encephalopathy #1
      timenormalized area #1
      prevalence cirrhotic patients #1
      brain edema disturbances #1
      increase alf #1
      cirrhotic patients falls #1
      lactulose oral neomycin #1
      lactate brain lactate #1
      patients previous falls #1
      encefalopatía #1
      Sign-in to see all concepts, it's free!

      Prominent publications by Juan Córdoba

      KOL-Index: 33377

      BACKGROUND: Hepatic encephalopathy is a brain dysfunction with neurological and psychiatric changes associated with liver insufficiency or portal-systemic shunting. The severity ranges from minor symptoms to coma. A Cochrane systematic review including 11 randomised clinical trials on branched-chain amino acids (BCAA) versus control interventions has evaluated if BCAA may benefit people with hepatic encephalopathy.

      OBJECTIVES: To evaluate the beneficial and harmful effects of BCAA versus ...

      Known for Hepatic Encephalopathy | Bias Trials | Amino Acids | Bcaa Beneficial | Mortality Quality
      KOL-Index: 32281

      BACKGROUND: Hepatic encephalopathy is a brain dysfunction with neurological and psychiatric changes associated with liver insufficiency or portal-systemic shunting. The severity ranges from minor symptoms to coma. A Cochrane systematic review including 11 randomised clinical trials on branched-chain amino acids (BCAA) versus control interventions has evaluated if BCAA may benefit people with hepatic encephalopathy.

      OBJECTIVES: To evaluate the beneficial and harmful effects of BCAA versus ...

      Known for Hepatic Encephalopathy | Bias Trials | Amino Acids | Bcaa Beneficial | Mortality Quality
      KOL-Index: 16427

      The natural history of hepatitis C virus (HCV) infection following liver transplantation and predictors of disease severity remain controversial. The aims of the study were to assess in a homogeneous population of 81 cyclosporine-based HCV-infected liver transplant recipients mostly infected with genotype 1b and undergoing strict protocol annual biopsies: 1) the histological progression of posttransplantation HCV disease and, in particular, the incidence of HCV-related graft cirrhosis ...

      Known for Rejection Episodes | Graft Cirrhosis | Genotype 1b | 5 Years | 1 Year Patients
      KOL-Index: 16244

      The Chronic Liver Disease Questionnaire (CLDQ) measures the impact on quality of life of chronic liver diseases, regardless of underlying etiology. The aim of this study was to develop a Spanish version of the CLDQ, and to assess its acceptability, reliability, validity, and sensitivity to change. The forward and back-translation method by bilingual translators, with expert panel and pilot testing on patients, was used for the adaptation. The final version was self-administered, together ...

      Known for Spanish Version | Chronic Liver | Life Assessment | Patients Cirrhosis | Disease Questionnaire
      KOL-Index: 16224

      Transmission of hepatitis B virus (HBV) infection from donors who are negative for hepatitis B surface antigen (HBsAg-) but positive for antibody to hepatitis B core antigen (anti-HBc+) has been reported. However, previous studies were generally performed in geographic regions with a low prevalence of anti-HBc positivity in the liver donor population. The aims of this study are (1) to assess the risk for de novo hepatitis B in recipients of livers from anti-HBc+ donors in an area of high ...

      Known for Novo Hepatitis | Liver Transplantation | Positive Donors | Anti Hbc | Hbv Infection
      KOL-Index: 15403

      BACKGROUND & AIMS: Minimal hepatic encephalopathy (MHE) is associated with falls, traffic accidents, and overt HE. However, the association with survival is controversial. We assessed the effects of MHE on the long-term survival of patients with cirrhosis.

      METHODS: We performed a prospective study of 117 consecutive patients with cirrhosis seen at a tertiary hospital in Seville, Spain (estimation cohort), followed by a validation study of 114 consecutive patients with cirrhosis seen at 4 ...

      Known for Patients Cirrhosis | Minimal Hepatic Encephalopathy | Critical Flicker Frequency | Meld Scores | Cff Hz
      KOL-Index: 15134

      It is shown that the glutamate-NO-cGMP pathway is impaired in cerebellum of rats with portacaval anastomosis in vivo as assessed by in vivo brain microdialysis in freely moving rats. NMDA-induced increase in extracellular cGMP in the cerebellum was significantly reduced (by 27%) in rats with portacaval anastomosis. Activation of soluble guanylate cyclase by the NO-generating agent S-nitroso-N-acetyl-penicillamine and by the NO-independent activator YC-1 was also significantly reduced (by ...

      Known for Soluble Guanylate Cyclase | Portacaval Anastomosis | Cerebellum Rats | Wistar Receptors | Content Modulation
      KOL-Index: 14609

      BACKGROUND & AIMS: Patients with cirrhosis hospitalized for an acute decompensation (AD) and organ failure are at risk for imminent death and considered to have acute-on-chronic liver failure (ACLF). However, there are no established diagnostic criteria for ACLF, so little is known about its development and progression. We aimed to identify diagnostic criteria of ACLF and describe the development of this syndrome in European patients with AD.

      METHODS: We collected data from 1343 ...

      Known for Aclf Patients | Liver Failure | Acute Decompensation | Distinct Syndrome | 28day Mortality Rate
      KOL-Index: 12617

      Hepatic encephalopathy can arise from portal-systemic shunting in the absence of intrinsic liver disease. However, there are few descriptions of this form of encephalopathy. Portal vein thrombosis is an infrequent disease that causes portal-systemic shunting. Episodic hepatic encephalopathy has been described in patients with portal vein thrombosis, but it is not known if these patients develop minimal hepatic encephalopathy. We designed a study to investigate the neurological ...

      Known for Portal Vein Thrombosis | Minimal Hepatic Encephalopathy | Neuropsychological Tests | Increase Brain Water | Patients Cirrhosis
      KOL-Index: 11962

      Minimal hepatic encephalopathy (MHE) is mainly diagnosed using psychometric tests such as the psychometric hepatic encephalopathy score (PHES). Despite the clinical and social relevance of MHE, psychometric testing is not widespread in routine clinical care. We assessed the usefulness of the critical flicker frequency (CFF), for the diagnosis of MHE and for the prediction of the development of overt episodes of HE. The normal range of PHES in the Spanish population was evaluated in a ...

      Known for Cff Mhe | Critical Flicker Frequency | Development Overt | Minimal Hepatic | Encephalopathy Humans
      KOL-Index: 11920

      BACKGROUND/AIMS: The natural history and predictors of HCV-related disease severity post-transplantation are uncertain. The aims of this study were to define the natural history of post-transplantation HCV infection by assessing the rate of fibrosis progression, to determine if the post-transplantation natural history differs from that observed pre-transplantation, and to identify predictors of post-transplantation disease progression.

      METHODS: Post-transplantation biopsies (mean: ...

      Known for Fibrosis Progression | Liver Transplantation | Year Post | Viral Factors | Laboratory Data
      KOL-Index: 11658

      Brain myo-inositol, an organic osmolyte, is decreased in cirrhotic patients with hepatic encephalopathy but appears unchanged in fulminant hepatic failure. An osmoregulatory response to the increase in brain glutamine may explain the decrease in brain myo-inositol; if this is the case, organic osmolytes may account for differences in the development of brain edema seen in acute or chronic liver failure. The response of myo-inositol and nine other organic osmolytes to the increase in ...

      Known for Brain Edema | Organic Osmolytes | Surgical Rats Rats | Myo Inositol | Osmoregulatory Response
      KOL-Index: 11127

      Bacterial infections are very common and represent one of the most important reasons of progression of liver failure, development of liver-related complications, and mortality in patients with cirrhosis. In fact, bacterial infections may be a triggering factor for the occurrence of gastrointestinal bleeding, hypervolemic hyponatremia, hepatic encephalopathy, kidney failure, and development of acute-on-chronic liver failure. Moreover, infections are a very common cause of repeated ...

      Known for Bacterial Infections | Immune Dysfunction | Patients Cirrhosis | Hepatic Encephalopathy | Gastrointestinal Bleeding
      KOL-Index: 11060

      BACKGROUND & AIMS: The pathogenesis of brain edema in fulminant hepatic failure is still unresolved. Mild hypothermia (33 degrees-35 degreesC) can ameliorate brain edema after traumatic brain injury. We evaluated mild hypothermia in a model of ammonia-induced brain edema in which accumulation of brain glutamine has been proposed as a key pathogenic factor.

      METHODS: After portacaval anastomosis, anesthetized rats were infused with ammonium acetate at 33 degrees, 35 degrees, and 37 ...

      Known for Mild Hypothermia | Brain Edema | Surgical Rats Rats | Intracranial Pressure | Portacaval Shunt
      KOL-Index: 10889

      BackgroundThe psychometric hepatic encephalopathy score (PHES) is a battery of neuropsychological tests used in the diagnosis of minimal hepatic encephalopathy (MHE).AimThe aim of this study was to construct and validate a dataset of normal values for the PHES.MethodsVolunteers and patients with cirrhosis with and without low-grade overt hepatic encephalopathy (OHE) were enrolled. All subjects completed the PHES battery, and possible modifying factors were assessed. Formulas to predict ...

      Known for Minimal Hepatic Encephalopathy | Patients Cirrhosis | Ohe Mhe | Neuropsychological Tests | Age Education

      Key People For Hepatic Encephalopathy

      Top KOLs in the world
      #1
      Peter Ferenci
      chronic hepatitis hepatic encephalopathy wilson disease
      #2
      Kevin Daniel Mullen
      hepatic encephalopathy chronic hepatitis portacaval shunt
      #3
      Juan Córdoba
      hepatic encephalopathy liver transplantation brain edema
      #4
      Roger F Butterworth∗
      hepatic encephalopathy acute liver failure thiamine deficiency
      #5
      Karin Weissenborn
      hepatic encephalopathy liver transplantation ischemic stroke
      #6
      Andrés T Blei
      brain edema hepatic encephalopathy acute liver failure

      Liver Unit, Department of Internal Medicine, Hospital Universitari Vall d'Hebron, VHIR, Universitat Autònoma de Barcelona, CIBERehd, Barcelona, Spain. | Liver Unit, Department of Internal Medicine, Hospital Universitari Vall d´Hebron, VHIR, Universit

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