• Disease
  • Hepatocellular
  • Hepatocellular Carcinoma
  • Gaetano Bertino

    Prominent publications by Gaetano Bertino

    KOL Index score: 16272

    BACKGROUND & AIMS: Studies have produced conflicting results of the incidence of hepatocellular carcinoma (HCC) in patients with hepatitis C virus-associated cirrhosis treated with direct-acting antivirals (DAAs). Data from clinics are needed to accurately assess the occurrence rate of HCC in patients with cirrhosis in the real world.

    METHODS: We collected data from a large prospective study of 2,249 consecutive patients (mean age = 65.4 years, 56.9% male) with hepatitis C ...

    Also Ranks for: Patients Svr |  hepatocellular carcinoma |  daas hcc |  antiviral agents |  cirrhosis treated
    KOL Index score: 16098

    BACKGROUND & AIMS: The effectiveness of direct-acting antivirals (DAAs) against hepatitis C virus (HCV), following successful treatment of early hepatocellular carcinoma (HCC), has been studied extensively. However, the benefit in terms of overall survival (OS) remains to be conclusively demonstrated. The aim of this study was to assess the impact of DAAs on OS, HCC recurrence, and hepatic decompensation.

    METHODS: We prospectively enrolled 163 consecutive patients with HCV-related ...

    Also Ranks for: Hcc Recurrence |  acting antivirals |  hepatic decompensation |  successful treatment |  patients daa
    KOL Index score: 13624

    BACKGROUND: We evaluated treatment modalities and survival in patients with hepatocellular carcinoma (HCC), by pre-treatment and 3-month post-treatment serum alpha-fetoprotein (AFP) levels and pre-treatment tumor diameters.

    METHODS: We retrospectively reviewed 57 patients treated for HCC in our department from January 2002 to December 2012, including their sex, type of hepatitis, Child class, pre-treatment tumor size, pre-treatment levels of albumin, aspartate aminotransferase (AST), ...

    Also Ranks for: Radiofrequency Ablation |  transarterial chemoembolization |  tumor size |  hepatocellular carcinoma |  hepatic resection
    KOL Index score: 12065

    BACKGROUND: Nonalcoholic fatty liver disease develops in patients with chronic hepatitis C. Interferon and ribavirin combination therapy is the standard treatment for chronic hepatitis C, but if present, NAFLD can reduce the virological response to anti-HCV therapies.

    OBJECTIVES: We determined whether the addition of rosuvastatin to interferon and ribavirin improves the sustained virological response (SVR) and reduces steatosis.

    PATIENTS AND METHODS: This study was a prospective, ...

    Also Ranks for: Chronic Hepatitis |  12 months |  ribavirin svr |  fatty liver |  rosuvastatin nafld
    KOL Index score: 9149

    BACKGROUND: Little is known about the association between cigarette smoking and asthma severity. We assessed smoking as a determinant of disease severity and control in a cohort of clinic-referred allergic subjects who developed new onset asthma.

    METHODS: Allergic rhinitis subjects with no asthma (n = 371) were followed-up for 10 years and routinely examined for asthma diagnosis. In those who developed asthma (n = 152), clinical severity and levels of asthma control were determined. ...

    Also Ranks for: Smokers Asthma |  allergic subjects |  cigarette smoking |  pack years |  new onset
    KOL Index score: 9066

    BACKGROUND: The health status of employees with chronic hepatitis C has major implications for organizations and labour market.

    OBJECTIVES: To assess the effects of Acetyl-L-Carnitine administration on work productivity, daily activity, and fatigue in subjects with chronic hepatitis C treated with Pegylated-Interferon-α2b and Ribavirin.

    PATIENTS AND METHODS: In this prospective, randomized, placebo controlled, double blind clinical trial, 30 subjects (Group A) with chronic hepatitis, ...

    Also Ranks for: Chronic Hepatitis |  hcv therapy |  12 months |  carnitine supplementation |  work performance
    KOL Index score: 9055

    BackgroundHepatitis C virus infection and interferon treatment are often associated with anxiety, depressive symptoms and poor health-related quality of life.To evaluate the Silybin-vitamin E-phospholipids complex effect on work ability and whether health related factors (anxiety and depression) were associated with work ability in subjects with chronic hepatitis C treated with Pegylated-Interferon-α2b (Peg–IFN) and Ribavirin (RBV).MethodsThirty-one patients (Group A) with chronic ...

    Also Ranks for: Work Ability |  depression anxiety |  chronic hepatitis |  12 months |  pegylated interferon
    KOL Index score: 8374

    Purpose: Portal vein thrombosis (PVT) is one of the severe complications of hepatocellular carcinoma (HCC). PVT deteriorates the liver, and its dysfunction increases the risk of bleeding, influencing the prognosis of patients with liver cirrhosis and HCC. The aim of our study was to investigate whether D-dimer testing could be a sensitive marker for the diagnosis and prognosis of HCC patients with PVT.

    Patients and methods: Between June 2010 and December 2015, 118 HCC patients were ...

    Also Ranks for: Portal Vein Thrombosis |  hepatocellular carcinoma |  hcc patients pvt |  sensitive marker |  liver cirrhosis
    KOL Index score: 8275

    Purpose: Hepatorenal syndrome (HRS) is a pre-renal-like dysfunction that generally onsets in cirrhotic patients presenting ascites. We investigated the improvement of renal function in subjects with hepatorenal syndrome after terlipressin administration and the survival times after this treatment. Fifty-two patients affected by cirrhosis, with diagnosis of hepatorenal syndrome were treated with intravenous terlipressin plus albumin (group A) or with albumin alone (group B). Liver and ...

    Also Ranks for: Renal Function |  patients cirrhosis |  terlipressin albumin |  survival treatment |  plasma renin activity
    KOL Index score: 8176

    Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in some areas of the world. In most cases, HCC is diagnosed at a late stage. Therefore, the prognosis of patients with HCC is generally poor. The recommended screening strategy for patients with cirrhosis includes the determination of serum α-fetoprotein (AFP) levels and an abdominal ultrasound every 6 months to detect HCC at an earlier stage. AFP, however, is a marker characterized by poor sensitivity and ...

    Also Ranks for: Tumor Carcinoma |  patients hcc |  serum markers |  early detection |  poor sensitivity
    KOL Index score: 7835

    BACKGROUND: During the past three decades, the incidence of hepatocellular carcinoma in the United States has tripled. The neuroendocrine character has been observed in some tumor cells within some hepatocellular carcinoma nodules and elevated serum chromogranin A also been reported in patients with hepatocellular carcinoma. The aim of this work was to investigate the role of serum concentration of chromogranin A in patients with hepatocellular carcinoma at different stages.

    METHODS: The ...

    Also Ranks for: Hepatocellular Carcinoma |  serum levels |  liver neoplasms |  biomarkers tumor |  case control
    KOL Index score: 7400

    INTRODUCTION: The Baveno VI consensus guidelines and an expanded algorithm suggest that transient elastography (TE) and platelet (PLT) count can be used to identify patients with cirrhosis who can avoid esophagogastroduodenoscopy (EGD). The primary aims of this study were to assess the ability of a simple algorithm, which uses only laboratory parameters, to predict medium/large esophageal varices (EV) in patients with hepatitis C virus (HCV) and cirrhosis from the Rete Sicilia Selezione ...

    Also Ranks for: Transient Elastography |  resisthcv criteria |  patients cirrhosis |  validation cohort |  noninvasive assessment


    Gaetano Bertino: Influence Statistics

    Sample of concepts for which Gaetano Bertino is among the top experts in the world.
    Concept World rank
    48 chronic hepatitis #1
    liver hemangioma giant #1
    199 antigen ca199 #1
    new directactingantiviral agents #1
    terms increasing quality #1
    protocols ifn #1
    hemangioma sizes patients #1
    september 2009 patients #1
    patients hepacivirus hepatitis #1
    liver hemangiomas diameter #1
    carbohydrate 199 #1
    post‐load insulin #1
    reduces post‐load #1
    hemangiomas diameter #1
    26 6 genotypes #1
    86 chronic hepatitis #1
    52 cirrhosis #1
    hepatitis pulmonary #1
    treatment eqindex #1
    hemangiomas 50 #1
    illness aminotransferases biomarkers #1
    hemangiomas size criteria #1
    abdominal ecography #1
    liver hemangiomas groups #1
    ca199 levels patients #1
    levels ca199 #1
    post‐load insulin resistance #1
    hemangiomas surgery #1
    compensated childa cirrhosis #1
    ca199 elevations #1
    hemangioma giant #1
    carcinoma future #1
    size category giant #1
    hemangiomas 50 diameter #1
    hemangioma sizes #1
    npv nmsc #2
    cigarettes living #2
    ends commonly #2
    molecular alterations solutions #2
    cancer 280 #2
    primary occult cancer #2
    hcc vitamin b6 #2
    responsibility hepatitis virus #2

    Key People For Hepatocellular Carcinoma

    Top KOLs in the world
    Jordi Bruix
    hepatocellular carcinoma liver transplantation patients hcc
    Josep María Llovet
    hepatocellular carcinoma advisory consultancy liver transplantation
    Vincenzo Mazzaferro
    hepatocellular carcinoma liver transplantation patients hcc
    Freddie Ian Bray
    cancer incidence nordic countries mortality rates
    Jacques Ferlay
    cancer incidence global burden latin america
    Hashem B EL‐SERAG
    united states hepatocellular carcinoma veterans affairs

    Gaetano Bertino:Expert Impact

    Concepts for whichGaetano Bertinohas direct influence:Hepatocellular carcinoma,  Chronic hepatitis,  Serum levels,  Patients chronic hepatitis,  Serum markers,  Hepatocellular carcinoma hcc,  Hepatic coma,  Transarterial chemoembolization.

    Gaetano Bertino:KOL impact

    Concepts related to the work of other authors for whichfor which Gaetano Bertino has influence:Hepatocellular carcinoma,  Hepatorenal syndrome,  Chronic hepatitis,  Liver disease,  Hcc patients,  Colorectal cancer,  Hcv infection.



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    Department of Experimental and Clinical Medicine, University of Catania, Policlinico “G. Rodolico”, Via S. Sofia n.78, 95123, Catania, Italy | Gastroenterology and Hepatology Unit, University Hospital Policlinico Vittorio Emanuele, Catania, Italy | P