MYOUNG KUK JANG

MYOUNG KUK JANG

Department Of Internal Medicine, Kangdong Sacred Heart Hospital Of Hallym University Medical Center, Seoul, Korea.

Direct Impact

Concepts for which MYOUNG KUK JANG has direct influence:

hepatocellular carcinoma
liver fibrosis
chronic hepatitis
pseudomembranous colitis
peptic ulcer
gastric cancer
viral breakthrough

External impact

Concepts related to the work of other authors for which MYOUNG KUK JANG has influence:

hepatocellular carcinoma
acutely decompensated cirrhosis
distinct pathophysiology
chronic hepatitis
fibrotic scar
gastric cancer
systemic inflammation

Prominent publications by MYOUNG KUK JANG

KOL-Index: 124 Acute-on-chronic liver failure (ACLF) is an important syndrome of liver failure that has a high risk of short-term mortality in patients with chronic liver disease. The development of ACLF is associated with proinflammatory precipitating events, such as infection, alcoholic hepatitis, and intense systemic inflammation. Recently, the role of the gut microbiome has increasingly emerged in ...
Known for
Alcohol-Induced Liver | Intense Systemic Inflammation | Dysbiosis Acute | Additionally Gut
KOL-Index: 47 Increased translocation of intestinal bacteria is a hallmark of chronic liver disease and contributes to hepatic inflammation and fibrosis. Here we tested the hypothesis that the intestinal microbiota and Toll-like receptors (TLRs) promote hepatocellular carcinoma (HCC), a long-term consequence of chronic liver injury, inflammation, and fibrosis. Hepatocarcinogenesis in chronically injured ...
Known for
Non-Bone-Marrow-Derived Resident Liver Cells | Intestinal Microbiota Tlr4 Activation | Tlrs | Late Stages
KOL-Index: 44 Hepatocellular carcinoma (HCC), a representative example of a malignancy with a poor prognosis, is characterized by high mortality because it is typically in an advanced stage at diagnosis and leaves very little hepatic functional reserve. Despite advances in medical and surgical techniques, there is no omnipotent tool that can diagnose HCC early and then cure it medically or surgically. ...
KOL-Index: 39 Hepatocellular carcinoma (HCC), a prototype of hypervascular tumors, is one of the most common malignancies in the world, especially hyperendemic in the Far East where chronic hepatitis B virus (HBV) infection is highly prevalent. It is characterized by the clinical feature of a poor prognosis or a high mortality due to its already far advanced stages at diagnosis. It is so multifactorial ...
Known for
Mechanism Hepatocarcinogenesis | Significance Mtas | Hcc Growth | Mta Order
KOL-Index: 38 Fibrosis and cancer represent two major complications of chronic liver disease. MicroRNAs have been implicated in the development of fibrosis and cancer, thus constituting potential therapeutic targets. Here, we investigated the role of microRNA-21 (miR-21), a microRNA that has been implicated in the development of fibrosis in multiple organs and has also been suggested to act as an ...
Known for
Fold 24-Fold Induction | Hsc-Specific Dicer Deletion | Mir-21 Antisense | Potential Therapeutic Targets
KOL-Index: 38 BACKGROUNDS/AIMS: It has been reported that tamoxifen may affect hepatoma cell growth in vitro by suppressing transforming growth factor beta-1 (TGF-beta1) expression, suggesting that tamoxifen might also retard fibrogenesis. Thus, we examined whether tamoxifen might suppress TGF-beta1 expression and consequently inhibit the process of hepatic fibrosis in vivo. METHODS: To induce periportal ...
Known for
Tgf-Beta Receptor | Reverse Transcriptase Polymerase Chain | 50 Male Sprague-Dawley Rats | Extents
KOL-Index: 35 According to the most current cancer impact statistics, third most commonly diagnosed cancer worldwide is colorectal cancer. Colon cancer, in addition to its physical symptoms, has been linked to mental health issues in patients, according to the study. Dealing with colorectal cancer drug chemotherapy may lead to depression and anxiety in some people. Others are affected by the physical and ...
KOL-Index: 33 Vertical transmission from mother to child, the main route of chronic hepatitis B virus (HBV) infection in the East Asia, is considered one of the most important predictors for the response to antiviral therapies as well as its complications such as cirrhosis and hepatocellular carcinoma. Therefore, it is critical in both etiologic and prognostic aspects to confirm whether or not chronic HBV ...
Known for
Hbv Genes | Chronic Hepatitis Virus | Pre-S Regions | Etiologic Prognostic Aspects
KOL-Index: 28 Hepatic hemangioma is the most common benign tumor of the liver. Most such hemangiomas are small, asymptomatic, and have an excellent prognosis. Giant hepatic hemangioma has been reported in the literature, but the exophytic and pedunculated forms of hepatic hemangioma are rare. A 56-year-old woman was referred to our hospital under the suspicion of having a gastric submucosal tumor. ...
Known for
Hemangioma Liver | Gastric Submucosal Tumor | Left Lateral Segment | Laparoscopic Resection
KOL-Index: 28 BACKGROUND AND AIMS: The risk factors for hepatocellular carcinoma (HCC) in immune inactive chronic hepatitis B (CHB) have not been clarified. The aim of this study was to investigate the predictive factors for HCC inimmune inactive CHB. METHODS: A total of 337 patients in immune inactive CHB were consecutively enrolled in Kangdong Sacred Heart Hospital from 1995 to 2017. Univariate and ...
Known for
Increased Levels2 | Predictive Hepatocellular | Hepatitis Chb | Carcinoma Immune

Department of Internal Medicine, Kangdong Sacred Heart Hospital of Hallym University Medical Center, Seoul, Korea.

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