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    • Charles L Loprinzi

      Charles L Loprinzi

      Mayo Clinic, Rochester, MN; | Division of Medical Oncology, Mayo Clinic, Rochester, MN 55902, USA;, cloprinzi@mayo.edu | Department of Oncology, Mayo Clinic, Rochester, MN ...

       

       

      KOL Resume for Charles L Loprinzi

      Year
      2022

      Mayo Clinic, Rochester, MN;

      2021

      Department of Oncology, Mayo Clinic, Rochester, MN 55905, United States. Electronic address:

      Mayo Clinic, Rochester, MN, USA

      2020

      Department of Oncology, Mayo Clinic Comprehensive Cancer Center, Rochester, United States of America

      Division of Medical Oncology, Mayo Clinic, Rochester, USA

      North Central Cancer Treatment Group, Mayo Clinic, Rochester, Minnesota

      Mayo Clinic, Rochester, MN, United States.

      2019

      Department of Oncology; Mayo Clinic; Rochester, Minnesota

      Mayo Clinic Rochester, Florida, USA

      Medical Oncology

      2018

      Department of Medical Oncology, Mayo Clinic, 200 First St SW, 55905, Rochester, MN, USA

      Division of Medical Oncology, Mayo Clinic, Rochester, MN

      2017

      Division of Medical Oncology, Mayo Clinic, Rochester, MN.

      Timothy Gilligan, Cleveland Clinic, Cleveland, OH ; Nessa Coyle, Memorial Sloan Kettering Cancer Center, New York; Ronald M. Epstein, University of Rochester School of Medicine, Rochester, NY; Richard M. Frankel, Regenstrief Institute, Indiana University School of Medicine, Indianapolis, IN; Donna L. Berry and Christopher S. Lathan, Dana-Farber Cancer Institute, Harvard Medical School; Vicki A. Jackson, Massachusetts General Hospital, Harvard Medical School, Boston; Carole Seigel, Patient/Advocacy Representative, Brookline, MA; Kari Bohlke, American Society of Clinical Oncology, Alexandria, VA; Esme Finlay, University of New Mexico School of Medicine, Albuquerque, NM; Charles L. Loprinzi, Mayo Clinic, Rochester, MN; and Lynne H. Nguyen and Walter F. Baile, The University of Texas MD Anderson Cancer Center, Houston, TX.

      Mayo Clinic Minnesota Department of Oncology Rochester Minnesota

      The Cancer Center

      2016

      Alliance Statistics and Data Center, Mayo Clinic (R.Q., H.L.), and Mayo Clinic (K.J.R., J.M.L., C.L.L.), Rochester, MN

      Mayo Clinic Cancer Center, Rochester, Minnesota

      2015

      Departments of Neurology, Oncology, Health Sciences Research, Division of Biomedical Statistics and Informatics, Mayo Clinic College of Medicine, Rochester, MN, USA

      Mayo Clinic Division of Medical Oncology Rochester Minnesota

      2014

      Mayo Clinic Cancer Center Rochester MN

      2013

      From the Department of Oncology and Cancer Center Statistics, Mayo Clinic, Rochester, MN.

      Mayo Clinic Rochester, 200 First Street, SW, 55905, Rochester, MN, USA

      2012

      Department of Oncology, Mayo Clinic, 55905, Rochester, MN, USA

      Mayo Clinic, Rochester, MN, United States

       

       

      Charles L Loprinzi: Influence Statistics

      Sample of concepts for which Charles L Loprinzi is among the top experts in the world.
      Concept World rank
      fluorouracilinduced stomatitis #1
      ru221408i #1
      treating institution intervention #1
      hot flashes treatment #1
      treatments modalities #1
      hfs ulabtka #1
      dfs 5fu #1
      1 month appetite #1
      sae δ − #1
      dmc assay #1
      cyclohexanols female #1
      drug humans interferons #1
      prevent oxaliplatin #1
      flashes pilot #1
      bridging editorial #1
      topic peripheral neuropathy #1
      nonhormonal agent #1
      impaired postural control #1
      positive indication prognosis #1
      hot flashes quality #1
      evidence cipn #1
      vitamin cipn #1
      patients paclitaxel polyneuropathy #1
      diphenhydraminelidocaineantacid #1
      patient followup studies #1
      cryotherapy mucositis #1
      therapeutic targets cipn #1
      oral cryotherapy #1
      duloxetine response patients #1
      metastatic disease initiation #1
      relatedness treatment #1
      purposehot #1
      uncertain gbu gbu #1
      2 study arms #1
      neuropathy randomized #1
      ncctg n08c1 #1
      oral cryotherapy patients #1
      alopecia ocular toxicity #1
      cancer hot #1
      leap 12 months #1
      anecdotal observations gabapentin #1
      fsfi udi #1
      cancerrelated fatigue interventions #1
      suggestion oral cryotherapy #1
      motor subscales #1
      underdescribers #1
      management genital symptoms #1
      symptom intervention #1
      deprivation symptoms #1
      magnesium camg #1
      differences neuropathy syndromes #1
      81 patients patients #1
      women 65 day #1
      data hot #1
      pregabalin paps #1
      underdescribers weeks #1
      trust oncologists competence #1
      topical cannabinoids patients #1
      slight appetite stimulation #1
      safety progestational agents #1
      reducing hot #1
      lidocaine antacid #1
      patients dosing guidelines #1
      painful oxaliplatininduced cipn #1
      n08cb alliance #1
      antiemetic prescribing #1
      alliance n08c1 #1
      8week observation period #1
      purposehot flashes #1
      patients 10 range #1
      rest psychostimulants #1
      flash score #1
      patients underdescribers #1
      association arhgef10 #1
      preceding 2 months #1
      paps fatigue #1
      arhgef10 cipn #1
      suggestion toxicity #1
      22 nonestrogenic management #1
      prevention cipn #1
      n08c3 #1
      randomized study lymphedema #1
      cipnsummarythere #1
      initiation tpn #1
      patients dfs predictions #1
      oncologists competence #1
      flaxseed bar #1
      hot flash frequency #1
      darbepoetin alfa head #1
      patients gabapentin #1
      attribution clinical trials #1
      anecdotal observations #1
      weeks hot #1
      accru study #1
      duloxetine response #1
      infliximab cancer #1
      patientreported outcomes balance #1
      survivors genitourinary syndrome #1
      gabapentin hot flashes #1
      hot flashes day #1
      cipn paps #1
      safety oestrogen #1
      pilot trial hands #1
      baseline week gabapentin #1
      megestrol acetate nausea #1
      iii double #1
      neoplasms placebos #1
      cipn development severity #1
      anorexia appetite #1
      leucovorin breast cancer #1
      subsequent chemotherapy cycles #1
      2007 guidelines guideline #1
      lignans 6 weeks #1
      inadequate control antidepressant #1
      lymphedemafree rates #1
      flashes venlafaxine #1
      acetate anorexia #1
      flaxseed bar lignans #1
      cyproheptadine appetite #1
      nonfluid #1
      vaginal dehydroepiandrosterone dhea #1
      paresthesia peripheral #1
      hormone deprivation symptoms #1
      difference cipn20 scores #1
      antiemetic prescribing practices #1
      nonestrogenic management #1
      isae data #1
      deprivation therapy patients #1
      newer antidepressants #1
      prominent clinical problem #1
      peripheral neuropathy #1
      patients 25 micrograms #1
      therapy numbness #1
      agents antihypertensive agents #1
      uncertain gbu #1
      gsm fsfi #1
      minocycline cipn #1
      numeracy adjuvant #1
      hot flash score #1
      ncctg trial n06ca #1
      placebos pregabalin quality #1
      improvements hot flashes #1
      n01c9 #1
      digital melt curve #1
      alliance study a221102 #1
      vaginal dehydroepiandrosterone #1
      cachexia megestrol #1
      weight megestrol acetate #1
      rs9657362 #1
      30 points 95 #1
      nonfluid weight gain #1
      underdescribing #1
      agents humans clinicians #1
      prestudy hypothesis #1
      altered sensory organization #1
      paclitaxel coasting phenomenon #1
      supportive cryotherapy #1
      bakplo symptoms #1
      overview crci #1
      toxicity anecdotal observations #1
      doubleblinded manner #1
      n08c1 #1
      treatment alteration #1
      centrally active agent #1
      compliance institutional guidelines #1
      stellate ganglion block #1
      bellergal #1
      postural instability chemotherapy #1
      recurrences clinical histories #1
      mouthwash diphenhydramine #1
      cinv day #1
      appetite stimulation patients #1
      cipn methods #1
      compassionate honesty #1
      week tamoxifen #1
      women megestrol acetate #1
      vaginal cytology women #1
      tools oncologists #1
      auc cryotherapy #1
      feet oxaliplatin #1
      aimss life #1
      supportive cytotoxic chemotherapy #1
      cipn function #1
      neuropathy 20 #1
      placebo 30 points #1
      prevention paps #1
      chemotherapy response rates #1
      megestrol acetate weeks #1
      increased difficulty patients #1
      flashes patients #1
      leap lymphedema #1
      eortc cipn20 #1
      flashes breast #1
      purposepaclitaxel #1
      authors 30 minutes #1
      adt cyclohexanecarboxylic acids #1
      tpn initiation death #1
      neuronal uptake transporters #1
      adjuvant numeracy #1
      lenolidamide #1
      aminobutyric acid adt #1
      cancer anorexia cachexia #1
      points doxepin #1
      rom leap #1
      ulabtka arm #1
      prevention oral cryotherapy #1
      natural postural instability #1
      lymphedema hrqol outcomes #1
      rose geranium #1
      pilot study minocycline #1
      induced neurotoxicity oct2 #1
      flaxseed hot flashes #1
      nonhormonal agents #1
      toxicities opioids #1
      flashes stellate #1
      median δ qs #1
      flashes objective #1
      qlq cipn20 #1
      flashes women #1
      cinv neoplasms vomiting #1
      fractures infertility #1
      life qlqcipn20 #1
      attribution treatment #1
      relatedness treatment arms #1
      oxybutynin doses #1
      intervention leap #1
      flashes week #1
      hormone deprivation cancer #1
      oral cryotherapy management #1
      bortezomib alters #1
      premenopause radiotherapy #1
      a151408 #1
      taxane treatment development #1
      antacid mouthwash #1
      rs17683288 #1
      paclitaxel weekly cryotherapy #1
      oral cryotherapy prevention #1
      middle aged minocycline #1
      cytotoxic chemotherapy supportive #1
      neuropathy prevention #1
      aps paclitaxel #1
      time publication attitude #1
      management hot flashes #1
      anthracycline data #1
      neuropathy data #1
      tingling #1
      purpose hot #1
      resected cutaneous melanomas #1
      qol reported difficulty #1
      phase iii evaluation #1
      hormone deprivation #1
      antidepressant gabapentin #1
      acute pain syndrome #1
      patients nasal vestibulitis #1
      pilot evaluation #1
      postsurgical neuropathic pain #1
      or1 year patients #1
      joints syndrome #1
      baseline prognosis #1
      antibiotic lozenge placebo #1
      megestrol acetate patients #1
      qolconclusionsthe #1
      estimated benefit dfs #1
      cipn common #1
      shooting burning #1
      placebo oral mucositis #1
      phytotherapy vitamin #1
      gabapentin hot #1
      cachexia trial #1
      prognosis items #1
      management hot #1
      paclitaxel favor #1
      doxepin mouthwash placebo #1
      cipn phase iii #1
      flashes treatment #1
      placebo 15 points #1
      pregabalin paclitaxel #1
      sensory neuropathy symptoms #1
      isaes #1
      preliminary evidence improvement #1
      alliance trial #1
      paclitaxel study arms #1
      chamomile mouthwash toxicity #1
      ambulatory patients opioids #1
      ulabtka hfs #1
      tested interventions lymphedema #1
      oncologists prognostic #1
      fluoxetine hot #1
      toxicity prospective trial #1
      fsfi 95 #1
      cancers prevalence #1
      placebo pilot trials #1
      pregenplus #1
      difficulty neuropathic pain #1
      life megestrol acetate #1
      grade peripheral neuropathy #1
      nociceptors putative mechanism #1
      n06ca #1
      stomatitis scores #1
      hot flash relief #1
      magnesium oxaliplatininduced neurotoxicity #1
      balance patientreported outcomes #1
      antidepressants gabapentin #1
      hec cisplatin therapy #1
      chemotherapy regimen type #1
      adam vte trial #1
      5fuinduced stomatitis #1
      symptoms hands #1
      judicious tpn #1
      cachexia dexamethasone #1
      patients physical examinations #1
      control hot flashes #1
      gabapentin arm #1
      benefit fluoxetine #1
      prtmethodsdata #1
      discrepancies women #1
      placebo anecdotal observations #1
      cryotherapy hands #1
      acetate doses #1
      baseline neuropathic pain #1
      lymphedema prevention education #1
      udi scores baseline #1
      numbness tingling #1
      suggested gabapentin #1
      cryotherapy auc #1
      highdose melphalan intervention #1
      flashes prospective #1
      newer antidepressants gabapentin #1
      dfs predictions adjuvant #1
      overview oncology providers #1
      neoplasm recurrence apixaban #1
      patients subcutaneous testosterone #1
      decrease hot #1
      95 neuropathic pain #1
      drowsiness unpleasant taste #1
      baseline prognosis values #1
      placebo arm gabapentin #1
      myalgias arthralgias #1
      flash scores #1
      individual patients understanding #1
      flash therapies #1
      cyclohexanecarboxylic acids gamma #1
      vte recurrence enoxaparin #1
      ulabtka #1
      oral mucositisrelated pain #1
      hot flashes #1
      oestrogen hot flashes #1
      cipn20 data #1
      device 5 weeks #1
      qolresultsfrom #1
      hfs trial #1
      residual hot flashes #1
      placebo arms percentage #1
      historical placebo response #1
      glutamine toxicity #1
      trial n00cb #1
      oncologists competence 95ci #1
      induced cipn #1
      polyneuropathy allelic variability #1
      aes relatedness #1
      nonhormonal therapies paroxetine #1
      alleviate hot #1
      ocular ice packs #1
      cipn clinical trial #1
      topic rectum surveys #1
      neoplasms climacteric #1
      coasting phenomenon #1
      baseline fsfi score #1
      fosaprepitant isae #1
      life study arms #1
      bothersome hot #1
      chemotherapy neuropathy #1
      symptoms cipn #1
      life leap #1
      recommended colorectal #1
      hot flash #1
      ganglion surveys humans #1
      gabapentin aminobutyric acid #1
      methylphenidate cancer patients #1
      pharmacologic therapeutics #1
      rs9657362 previous study #1
      extensive animal data #1
      flashes common #1
      breakthrough nausea patients #1
      active nonhormonal #1
      udi δ − #1
      hot flash control #1
      acetate hot #1
      diseases pilot #1
      nonfluid bodyweights #1
      olanzapine projects vomiting #1
      arthralgia breast life #1
      cipn20 #1
      pharmacological targeting oct2 #1
      cipn data #1
      data clinical histories #1
      gait testing patients #1
      accru trial #1
      symptoms hormone deprivation #1
      developed mucositis #1
      alliance n08ca #1
      1year survival trials #1
      accru study ru221408i #1
      95 increased difficulty #1
      male megestrol life #1
      isae anthracycline #1
      cachexia studies #1
      n08ca association #1
      patients hot flashes #1
      anorexia antineoplastic agents #1
      lymphedema incidence intervention #1
      daily questionnaires #1
      ctcae grade #1
      education lymphedema prevention #1
      physical consequences cipn #1
      20 data patients #1
      recommendation prevention #1
      symptoms feet #1
      oral mucosa study #1
      items uncertain gbu #1
      fourth treatment week #1
      antineoplastic agents nrs #1
      bothersome hot flashes #1
      dronabinol megestrol acetate #1
      routine feces sensitivity #1
      education lymphedema education #1
      women male megestrol #1
      tingling numbness #1
      5fu adjuvant #1
      infliximab lung #1
      treatment hot flashes #1
      crc patients 95 #1
      cachexia carcinoma life #1
      taxane infusion #1
      nonhormonal agents treatment #1
      peripheral neuropathy paclitaxel #1
      lymphedemafree rates groups #1
      efficacy gabapentin #1
      5fuinduced ocular toxicity #1
      balance impairments patients #1
      toxicity gabapentin #1
      nonhormonal hot #1
      patients cancer anorexia #1
      female services tpn #1
      illness neuropathic symptoms #1
      bakplo placebo #1
      longitudinal continuation #1
      antiserotonergic drug #1
      efficacy agent #1
      cisplatin therapy cinv #1
      patients spray product #1
      hot flash mechanism #1
      doxepin mouthwash #1
      stomatitis administration #1
      mouthwash placebo #1
      burning pain #1
      cipn postural control #1
      snv rs9657362 #1
      flashes gabapentin #1
      treatment attribution #1
      regional hypothermia burden #1
      cachexia cyproheptadine #1
      acetate dexamethasone #1
      treatment symptom intervention #1
      compliance institutional guideline #1
      incurable cancer records #1
      ulabtka placebo cream #1
      cipnmethodspatients #1
      doxepin mouthwash patients #1
      hot flashes weeks #1
      survival tpn initiation #1
      leap rom #1
      therapy hot #1
      flashes quality #1
      leucovorin breast #1
      rs2294039 #1
      amines antidepressive #1
      topical cannabinoids #1
      patients ulabtka #1
      eortc cipn #1
      hot flashes patients #1
      hot flash activity #1
      supportive nsclc #1
      mascc isoo guidelines #1
      individuals cipn #1
      progestational agents patients #1
      uniscale qol baseline #1
      n00cb #1
      women inadequate control #1
      pilot trials venlafaxine #1
      gene arhgef10 #1
      flashes prostate #1
      treating hot #1
      reduction hot #1
      managing hot #1
      cipn agents #1
      mascc isoo evidence #1
      tpn death #1
      hot flashes acceptability #1
      balance gait testing #1
      attribution percentage #1
      δ − 95 #1
      alleviating hot #1
      male megestrol megestrol #1
      conducted studies hrt #1
      aes placebo arm #1
      agents cyclohexanecarboxylic #1
      managing hot flashes #1
      dronabinol combination #1
      antibiotic lozenge #1
      papsmethodspatients #1
      acetate versus #1
      aminobutyric acid hec #1
      subcutaneous testosterone improvements #1
      outcomes study points #1
      5 methylphenidate #1
      single snv rs9657362 #1
      cachexia cancer anorexia #1
      topical keratolytic #1
      points diphenhydramine #1
      enoxaparin cvte #1
      antidepressive agents gamma #1
      sensory subscale #1
      agents cipn #1
      hot flash scores #1
      acetate appetite #1
      nonhormonal #1
      replacement testosterone andropause #1
      effects limited efficacy #1
      placebo 15 glutathione #1
      megestrol acetate #1
      benefit 5fu #1
      ganglion surveys #1
      numbness scores #1
      burden alopecia #1
      ocular ice #1
      institutional guidelines patients #1
      preliminary promising data #1
      ssc device prototype #1
      studies cyproheptadine #1
      numbness hands #1
      established cipn #1
      numeracy benefit #1
      isae #1
      testosterone improvements #1
      cipn20 questionnaire #1
      numerical analogue scale #1
      sham acupuncture participants #1
      cipn topical gel #1
      humans ganglion surveys #1
      paclitaxel acute #1
      ncctg n08c3 #1
      head therapeutic equivalency #1
      chamomile mouthwash #1
      flashes androgen #1
      dmc samples #1
      compounded topical gel #1
      tpn longterm survival #1
      cipn20 sensory #1
      gas menopause patient #1
      oxybutynin hot flashes #1
      life cipn #1
      oral mucositis alopecia #1
      glutathione cipn #1
      gabapentin antidepressant #1
      bupropion nicotine dependence #1
      patientcompleted questionnaires #1
      based chemotherapy isae #1
      cancerassociated anorexia cachexia #1
      43 oral complications #1
      oestrogen survivors #1
      12 months anticoagulation #1
      5 weeks device #1
      patients placebo pellet #1
      eortc qlqcipn20 instrument #1
      disease patient factors #1
      loe prevention #1
      treatment hot #1
      placebo mouthwash #1
      items positive indication #1
      authors 115 patients #1
      creatine placebo groups #1
      suggestion pregabalin #1
      − fsfi #1
      nonfluid weight #1
      effects hot flashes #1
      combination chemotherapy hec #1
      isae patients #1
      skin dermatitis trials #1
      adjuvant numeracy calculators #1
      a151408 study data #1
      acceptability ssc device #1
      populations neurologic humans #1
      oil nasal #1
      toxicity ocular #1
      neuropathic pain difficulty #1
      tpn female services #1
      n08cb #1
      extreme phenotyping #1
      adam vte #1
      hot flash data #1
      score baseline values #1
      nsclc response rate #1
      nasal vestibulitis #1
      discrepancies clinicians assessment #1
      paclitaxel polyneuropathy #1
      pain chemotherapy #1
      complete response authors #1
      modalities cancer patients #1
      records adult patients #1
      gabapentin baseline week #1
      baseline week followup #1
      patientreported nasal symptoms #1
      understanding potential benefits #1
      137 patients cycle #1
      hot flashes gabapentin #1
      dmc mutations #1
      day cisplatin therapy #1
      patients highdose interferon #1
      n08ca patients #1
      cipn adult #1
      background hot #1
      small cell continuity #1
      neuropathic symptoms breast #1
      week hot #1
      pilot trials citalopram #1
      olanzapine arm emesis #1
      cvte rivaroxaban #1
      venous toxicity fosaprepitant #1
      study stool samples #1
      tools hypothetical scenarios #1
      bakplo #1
      hot flashes women #1
      n08ca #1
      hfs symptoms patients #1
      drowsiness doxepin mouthwash #1
      prevention induced cipn #1
      inadequate hot #1
      acute symptoms cycle #1
      effects cipn #1
      severe stomatitis #1
      cipn nervous diseases #1
      baseline assessment week #1
      alliance a151724 #1
      daily hot #1
      guidelineendorsed treatment #1
      backgrounddehydroepiandrosterone #1
      treatment cipn #1
      65 day #1
      cipn trials #1
      pilot trials efficacy #1
      weight loss investigation #1
      oncology providers crci #1
      prominent toxicity #1
      hormonal ablation andropause #1
      95 doxepin mouthwash #1
      weeks hot flashes #1
      patients megestrol acetate #1
      receiving fluorouracil #1
      current trial #1
      toxicity agent #1
      revisitation doc #1
      2007 guidelines suggestion #1
      chemotherapy treatment chemotherapy #1
      individuals impaired balance #1
      placebo drowsiness #1
      hours nighttime sleep #1
      favor placebo #1
      study dmc assay #1
      response relationship odc #1
      patients olanzapine arm #2
      tamoxifen metabolism evidence #2
      hot flashes pregabalin #2
      979254 #2
      neuropathy paclitaxel #2
      inadequate benefit #2
      ecog nutrition score #2
      vitamin hot flashes #2
      randomized study mometasone #2
      cipn cases #2
      conclusions original report #2
      colonoscopically normal patients #2
      scrambler therapy management #2
      sunscreen arms #2
      pa outcomes pros #2
      day average pain #2
      patients black cohosh #2
      120000 epoetin alfa #2
      study n08cb alliance #2
      methylphenidate cancer #2
      provider assessed #2
      lamotrigine neuropathic symptoms #2
      trial suggestion #2
      anthrapyrazoles piroxantrone #2
      cipn primary outcomes #2
      treatment baseline week #2
      stage disease 5fu #2
      control arms rate #2
      n01c4 #2
      time randomized study #2
      cipn antineoplastic agents #2
      aprepitan #2
      trials suggested #2
      anthraquinones agents breast #2
      pilot citalopram #2
      randomized receive #2
      hot flash trials #2
      neoplasms double #2
      venlafaxine control #2
      dronabinol combination therapy #2
      historic controls npy #2
      singleagent megestrol acetate #2
      dhea 4 weeks #2
      sensitivity screenrelevant neoplasms #2
      95 indirect estimates #2
      cachexia decision #2
      life treatment weeks #2
      hot flash management #2
      original report mometasone #2
      magnesium oxaliplatin #2
      sdt2 sdt1 #2
      guaninemethyltransferase #2
      differences mometasone #2
      placebo situ carcinoma #2
      feet 18 months #2
      oxybutynin women #2
      appetite improvement #2
      fsfi score baseline #2
      ncctg trial #2
      infliximab docetaxel #2
      reduce hot #2
      placebo bar #2
      study arms #2
      patients shark cartilage #2
      study arms quality #2
      dronabinol versus #2
      placebo combination therapy #2
      daily mmf radiotherapy #2
      life 4week intervention #2
      life cipn20 #2
      cipn cancer survivors #2
      sdt2 hemoccult #2
      doses megestrol #2
      432 smokers treatment #2
      citalopram cyclohexanols humans #2
      nutrition scores physicians #2
      vitamin hot #2
      cipn20 factor analysis #2
      toxicity profiles time #2
      gabapentin symptoms #2
      hot flash studies #2
      docetaxel serum concentrations #2
      study treatment citalopram #2
      16 hemoccult #2
      cdf score #2
      dermatitis symptom evolution #2
      illness tetracycline egfr #2
      weight concerns 26 #2
      levetiracetam 4 weeks #2
      cohosh treatment #2
      nonestrogenic hot #2
      placebo breast radiotherapy #2
      mometasone time #2
      receiving megestrol #2
      breast cancer venlafaxine #2
      intermediate term efficacy #2
      starting tamoxifen #2
      trial acetate doses #2
      postchemotherapy rheumatism #2
      piroxantrone women #2
      qol hb increment #2
      real patients treatment #2
      anorexia antineoplastic #2
      oxaliplatin induced neurotoxicity #2
      pain ≥4 10 #2
      patients 40k arm #2
      n03cb #2
      evaluating venlafaxine #2
      central cancer #2
      adjuvant 5fu models #2
      appetite dissent disputes #2
      95 oral placebo #2
      irox folfox auc #2
      “use vitamin #2
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      united #27151
      histologically #27323
      inherited #27404
      neoplasm proteins #27717
      prognosis retrospective #27768
      systematic #27775
      functional #27808
      0005 #28001
      predisposition #28007
      preoperative #28036
      skeletal #28185
      longitudinal #28189
      estimated #28229
      leads #28238
      missing #28264
      acid #28356
      anti inflammatory #28360
      correlate #28365
      larger #28581
      sex factors #28629
      causing #28688
      sensitivity #28740
      vary #28851
      11 #28869
      matched #28979
      represents #29258
      detection #29343
      active #29413
      differentiate #29510
      objectives #29543
      completely #29721
      factual #29750
      databases factual #29793
      varied #30036
      excluded #30077
      quantified #30091
      occurs #30143
      adjusted #30189
      logistic #30241
      underlying #30508
      allowed #30520
      national #30765
      odds #30909
      001 #30996
      regression #31005
      unchanged #31053
      separately #31068
      characterize #31283
      recombinant #31415
      adolescent #31473
      dose dependent #31787
      age #31875
      lacking #31939
      attenuated #31971
      lower #32078
      correlated #32273
      postoperative #32309
      negative #32666
      growth factor #33089
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      understood #33957
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      reduced #34048
      implicated #34054
      confidence #34153
      defined #34517
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      followup #36532
      diagnosed #36787
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      remains #37899
      multivariate #38132
      independent #38886
      measured #38991
      proto oncogene #39186
      proto #39814
      biomarkers tumor #39899
      examined #40295
      retrospective studies #42973
      underwent #43365
      95 confidence #44196

       

      Prominent publications by Charles L Loprinzi

      KOL-Index: 16482

      Importance: Zoledronic acid, a third-generation aminobisphosphonate, reduces the incidence of skeletal-related events and pain in patients with bone metastases. The optimal dosing interval for zoledronic acid is uncertain.

      Objective: To determine whether zoledronic acid administered every 12 weeks is noninferior to zoledronic acid administered every 4 weeks.

      Design, Setting, Participants: Randomized, open-label clinical trial conducted at 269 academic and community sites in the United ...

      Known for Zoledronic Acid | Bone Metastases | 2 Years | Patients Breast Cancer | Skeletal Events
      KOL-Index: 16399

      Postmenopausal women with breast cancer (BC) are at increased risk for bone loss. Bisphosphonates improve bone mineral density (BMD) in normal postmenopausal women. The purpose of this study was to determine if immediate treatment with zoledronic acid preserves BMD in postmenopausal women with BC starting letrozole after tamoxifen. Postmenopausal women with BC completing tamoxifen were treated with daily letrozole 2.5 mg/vitamin D 400 I.U., calcium 500 mg twice daily and were randomized ...

      Known for Postmenopausal Women | Bone Loss | Zoledronic Acid | Breast Cancer | Versus Delayed
      KOL-Index: 13693

      PURPOSE: Risedronate prevents bone loss in postmenopausal women. The purpose of this study was to determine whether risedronate prevents bone loss in premenopausal women undergoing chemotherapy for breast cancer.

      PATIENTS AND METHODS: Premenopausal women undergoing chemotherapy for breast cancer were treated with oral calcium 600 mg and vitamin D 400 U daily and randomly assigned to receive oral risedronate 35 mg weekly or placebo, with all these therapies beginning within a month of the ...

      Known for Bone Loss | Premenopausal Women | Breast Cancer | 1 Year | Bmd Baseline
      KOL-Index: 13389

      BACKGROUND: Cisplatin is primarily used for treatment of ovarian and testicular cancer. Oxaliplatin is the only effective treatment for metastatic colorectal cancer. Both are known to cause dose related, cumulative toxic effects on the peripheral nervous system and thirty to forty percent of cancer patients receiving these agents experience painful peripheral neuropathy. The mechanisms underlying painful platinum-induced neuropathy remain poorly understood. Previous studies have ...

      Known for Trpv1 Trpa1 | Transient Receptor | Cisplatin Oxaliplatin | Mechanical Allodynia | Treated Mice
      KOL-Index: 13187

      PURPOSE: Functional iron deficiency may impair response to erythropoiesis-stimulating agents (ESAs) in iron-replete patients with chemotherapy-associated anemia (CAA). This study evaluated whether coadministration of parenteral iron improves ESA efficacy in patients with CAA.

      PATIENTS AND METHODS: This prospective, multicenter, randomized trial enrolled 502 patients with hemoglobin (Hb) less than 11 g/dL who were undergoing chemotherapy for nonmyeloid malignancies. All patients received ...

      Known for Oral Iron | Darbepoetin Alfa | Erythropoietic Response | Phase Iii | Ferric Gluconate
      KOL-Index: 12870

      To develop a framework for the definition and classification of cancer cachexia a panel of experts participated in a formal consensus process, including focus groups and two Delphi rounds. Cancer cachexia was defined as a multifactorial syndrome defined by an ongoing loss of skeletal muscle mass (with or without loss of fat mass) that cannot be fully reversed by conventional nutritional support and leads to progressive functional impairment. Its pathophysiology is characterised by a ...

      Known for Cancer Cachexia | International Consensus | Definition Classification | Weight Loss | Reduced Food Intake
      KOL-Index: 12824

      PURPOSE: Although it is well-established that fluorouracil- (FU-) based adjuvant therapy improves survival for patients with resected high-risk colon cancer, the magnitude of adjuvant therapy benefit across specific subgroups and for individual patients has been uncertain.

      PATIENTS AND METHODS: Using a pooled data set of 3,302 patients with stage II and III colon cancer from seven randomized trials comparing FU + leucovorin or FU + levamisole to surgery alone, we performed an analysis ...

      Known for Adjuvant Therapy | Nodal Status | Colon Cancer | Survival Stage | Pooled Analysis
      KOL-Index: 12701

      OBJECTIVE: To compare the combination of a nicotine inhaler and bupropion to either treatment alone for initiating smoking abstinence and relapse prevention.

      METHODS: Smokers were randomized to receive a nicotine inhaler, bupropion, or both for 3 months. At 3 months, smoking-abstinent study participants were randomized to their initial medications or placebo. Participants who were smoking at 3 months were randomized to an alternative treatment regimen or placebo. This study was conducted ...

      Known for Relapse Prevention | Nicotine Inhaler | Bupropion Placebo | Smoking Abstinence | Treatment Phase
      KOL-Index: 12639

      BACKGROUND: Experimental studies in animals and observational studies in humans suggest that regular aspirin use may decrease the risk of colorectal adenomas, the precursors to most colorectal cancers.

      METHODS: We conducted a randomized, double-blind trial to determine the effect of aspirin on the incidence of colorectal adenomas. We randomly assigned 635 patients with previous colorectal cancer to receive either 325 mg of aspirin per day or placebo. We determined the proportion of ...

      Known for Colorectal Adenomas | Patients Aspirin | Observational Studies | Relative Risks | Cancer Adenoma
      KOL-Index: 12619

      BACKGROUND: Stool DNA testing is a new approach to colorectal cancer detection. Few data are available from the screening setting.

      OBJECTIVE: To compare stool DNA and fecal blood testing for detection of screen-relevant neoplasia (curable-stage cancer, high-grade dysplasia, or adenomas >1 cm).

      DESIGN: Blinded, multicenter, cross-sectional study.

      SETTING: Communities surrounding 22 participating academic and regional health care systems in the United States.

      PARTICIPANTS: 4482 ...

      Known for Stool Dna | Blood Test | Screen Detection | Colorectal Neoplasia | Humans Specificity
      KOL-Index: 12464

      PURPOSE: Recent changes have occurred in the presurgical planning for breast cancer, including the introduction of preoperative breast magnetic resonance imaging (MRI). We sought to analyze the trends in mastectomy rates and the relationship to preoperative MRI and surgical year at Mayo Clinic, Rochester, MN.

      PATIENTS AND METHODS: We identified 5,405 patients who underwent surgery between 1997 and 2006. Patients undergoing MRI were identified from a prospective database. Trends in ...

      Known for Mastectomy Rates | Magnetic Resonance | Patients Mri | Surgery Type | Surgical Year
      KOL-Index: 12354

      PURPOSE: Previous double-blind, placebo-controlled, randomized clinical trials have demonstrated that both corticosteroids and progestational agents do partially alleviate cancer anorexia/cachexia. Pilot information suggested that an anabolic corticosteroid might also improve appetite in patients with cancer anorexia/cachexia. The current trial was developed to compare and contrast a progestational agent, a corticosteroid, and an anabolic corticosteroid for the treatment of cancer ...

      Known for Cancer Anorexia | Megestrol Acetate | Cachexia Patients | Progestational Agents | Corticosteroid Treatment
      KOL-Index: 12321

      BACKGROUND: Vasomotor hot flashes are a common symptom in women during menopause and in men who have undergone androgen-deprivation therapy for prostate cancer. Although treatment with estrogens in women and androgens in men can attenuate these symptoms, these hormones may be contraindicated in women with breast cancer and in men with prostate cancer. Pilot trials have suggested that the progestational agent megestrol acetate can ameliorate hot flashes in both groups of ...

      Known for Megestrol Acetate | Hot Flashes | Women Breast Cancer | Deprivation Therapy | Weeks Placebo

      Key People For Hot Flashes

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      Charles L Loprinzi
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      Charles L Loprinzi:Expert Impact

      Concepts for whichCharles L Loprinzihas direct influence:Hot flashes,  Breast cancer,  Megestrol acetate,  Peripheral neuropathy,  Scrambler therapy,  Phase iii,  Newer antidepressants,  Hot flash.

      Charles L Loprinzi:KOL impact

      Concepts related to the work of other authors for whichfor which Charles L Loprinzi has influence:Breast cancer,  Hot flashes,  Adjuvant chemotherapy,  Quality life,  Weight loss,  Oral mucositis,  Neuropathic pain.


       

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      Mayo Clinic, Rochester, MN; | Division of Medical Oncology, Mayo Clinic, Rochester, MN 55902, USA;, cloprinzi@mayo.edu | Department of Oncology, Mayo Clinic, Rochester, MN 55905, United States. Electronic address: cloprinzi@mayo.edu. | Mayo Clinic, R

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