• KOL
    • Charles L Loprinzi
    • Charles L Loprinzi

      Charles L Loprinzi

      Mayo Clinic, Rochester, MN; | Division of Medical Oncology, Mayo Clinic, Rochester, MN 55902, USA;, cloprinzi@mayo.edu | Department of Oncology, Mayo Clinic, Rochester, MN ...

       

       

      Kol Lebenslauf für Charles L Loprinzi

      Year
      2022

      Mayo Clinic, Rochester, MN;

      2021

      Department of Oncology, Mayo Clinic, Rochester, MN 55905, United States. Electronic address:

      Mayo Clinic, Rochester, MN, USA

      2020

      Department of Oncology, Mayo Clinic Comprehensive Cancer Center, Rochester, United States of America

      Division of Medical Oncology, Mayo Clinic, Rochester, USA

      North Central Cancer Treatment Group, Mayo Clinic, Rochester, Minnesota

      Mayo Clinic, Rochester, MN, United States.

      2019

      Department of Oncology; Mayo Clinic; Rochester, Minnesota

      Mayo Clinic Rochester, Florida, USA

      Medical Oncology

      2018

      Department of Medical Oncology, Mayo Clinic, 200 First St SW, 55905, Rochester, MN, USA

      Division of Medical Oncology, Mayo Clinic, Rochester, MN

      2017

      Division of Medical Oncology, Mayo Clinic, Rochester, MN.

      Timothy Gilligan, Cleveland Clinic, Cleveland, OH ; Nessa Coyle, Memorial Sloan Kettering Cancer Center, New York; Ronald M. Epstein, University of Rochester School of Medicine, Rochester, NY; Richard M. Frankel, Regenstrief Institute, Indiana University School of Medicine, Indianapolis, IN; Donna L. Berry and Christopher S. Lathan, Dana-Farber Cancer Institute, Harvard Medical School; Vicki A. Jackson, Massachusetts General Hospital, Harvard Medical School, Boston; Carole Seigel, Patient/Advocacy Representative, Brookline, MA; Kari Bohlke, American Society of Clinical Oncology, Alexandria, VA; Esme Finlay, University of New Mexico School of Medicine, Albuquerque, NM; Charles L. Loprinzi, Mayo Clinic, Rochester, MN; and Lynne H. Nguyen and Walter F. Baile, The University of Texas MD Anderson Cancer Center, Houston, TX.

      Mayo Clinic Minnesota Department of Oncology Rochester Minnesota

      The Cancer Center

      2016

      Alliance Statistics and Data Center, Mayo Clinic (R.Q., H.L.), and Mayo Clinic (K.J.R., J.M.L., C.L.L.), Rochester, MN

      Mayo Clinic Cancer Center, Rochester, Minnesota

      2015

      Departments of Neurology, Oncology, Health Sciences Research, Division of Biomedical Statistics and Informatics, Mayo Clinic College of Medicine, Rochester, MN, USA

      Mayo Clinic Division of Medical Oncology Rochester Minnesota

      2014

      Mayo Clinic Cancer Center Rochester MN

      2013

      From the Department of Oncology and Cancer Center Statistics, Mayo Clinic, Rochester, MN.

      Mayo Clinic Rochester, 200 First Street, SW, 55905, Rochester, MN, USA

      2012

      Department of Oncology, Mayo Clinic, 55905, Rochester, MN, USA

      Mayo Clinic, Rochester, MN, United States

       

       

      Charles L Loprinzi: Einflussstatistik

      Beispiel von Konzepten, für die Charles L Loprinzi gehört zu den Top -Experten der Welt.
      Concept World rank
      patients placebo pellet #1
      paclitaxel favor #1
      numeracy benefit #1
      rom leap #1
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      postural instability chemotherapy #1
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      rs9657362 #1
      oral cryotherapy #1
      compliance institutional guidelines #1
      study stool samples #1
      life cipn #1
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      uncertain gbu #1
      recommendation prevention #1
      effects limited efficacy #1
      appetite stimulation patients #1
      vaginal cytology women #1
      nonfluid #1
      suggestion oral cryotherapy #1
      individuals cipn #1
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      anthracycline data #1
      topical keratolytic #1
      cipn topical gel #1
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      placebo 15 glutathione #1
      replacement testosterone andropause #1
      oral mucosa study #1
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      prevention induced cipn #1
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      oxybutynin doses #1
      agents cyclohexanecarboxylic #1
      placebo oral mucositis #1
      isae patients #1
      137 patients cycle #1
      pharmacologic therapeutics #1
      nonfluid weight #1
      compliance institutional guideline #1
      eortc cipn20 #1
      65 day #1
      hot flashes day #1
      n00cb #1
      agents cipn #1
      evidence cipn #1
      n08c3 #1
      newer antidepressants #1
      disease patient factors #1
      points doxepin #1
      pharmacological targeting oct2 #1
      hormone deprivation cancer #1
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      cytotoxic chemotherapy supportive #1
      pregabalin paclitaxel #1
      glutathione cipn #1
      weight loss investigation #1
      judicious tpn #1
      single snv rs9657362 #1
      hot flashes gabapentin #1
      peripheral neuropathy #1
      aminobutyric acid adt #1
      benefit 5fu #1
      newer antidepressants gabapentin #1
      ocular ice packs #1
      flash score #1
      ulabtka hfs #1
      increased difficulty patients #1
      relatedness treatment arms #1
      a151408 study data #1
      megestrol acetate #1
      preceding 2 months #1
      n08ca #1
      tingling #1
      bupropion nicotine dependence #1
      agents humans clinicians #1
      authors 30 minutes #1
      nociceptors putative mechanism #1
      drowsiness doxepin mouthwash #1
      isae #1
      flashes venlafaxine #1
      anecdotal observations gabapentin #1
      pilot trials efficacy #1
      gait testing patients #1
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      compounded topical gel #1
      metastatic disease initiation #1
      life leap #1
      highdose melphalan intervention #1
      flashes gabapentin #1
      toxicities opioids #1
      infliximab cancer #1
      combination chemotherapy hec #1
      leucovorin breast #1
      alliance n08c1 #1
      historical placebo response #1
      patients megestrol acetate #1
      arhgef10 cipn #1
      premenopause radiotherapy #1
      glutamine toxicity #1
      lidocaine antacid #1
      education lymphedema prevention #1
      chemotherapy treatment chemotherapy #1
      digital melt curve #1
      hot flashes patients #1
      olanzapine projects vomiting #1
      flashes quality #1
      a151408 #1
      rose geranium #1
      patients cancer anorexia #1
      creatine placebo groups #1
      underdescribers #1
      life study arms #1
      weight megestrol acetate #1
      points diphenhydramine #1
      modalities cancer patients #1
      accru study #1
      aps paclitaxel #1
      tools oncologists #1
      adam vte trial #1
      lymphedema prevention education #1
      survival tpn initiation #1
      ganglion surveys humans #1
      efficacy agent #1
      daily questionnaires #1
      safety progestational agents #1
      oil nasal #1
      prevention cipn #1
      δ − 95 #1
      underdescribers weeks #1
      megestrol acetate weeks #1
      benefit fluoxetine #1
      stomatitis administration #1
      flashes breast #1
      supportive cryotherapy #1
      suggestion toxicity #1
      hot flashes weeks #1
      cipn clinical trial #1
      olanzapine arm emesis #1
      placebo anecdotal observations #1
      cancers prevalence #1
      duloxetine response patients #1
      items uncertain gbu #1
      complete response authors #1
      phase iii evaluation #1
      flashes prospective #1
      adjuvant numeracy calculators #1
      ganglion surveys #1
      symptom intervention #1
      uncertain gbu gbu #1
      chemotherapy regimen type #1
      neuropathic pain difficulty #1
      managing hot flashes #1
      myalgias arthralgias #1
      darbepoetin alfa head #1
      neoplasms placebos #1
      nonhormonal #1
      numeracy adjuvant #1
      n08cb #1
      painful oxaliplatininduced cipn #1
      drowsiness unpleasant taste #1
      topical cannabinoids patients #1
      placebo 30 points #1
      adam vte #1
      paclitaxel weekly cryotherapy #1
      sham acupuncture participants #1
      doxepin mouthwash placebo #1
      antidepressants gabapentin #1
      fsfi 95 #1
      patients paclitaxel polyneuropathy #1
      acetate hot #1
      patientreported nasal symptoms #1
      lymphedemafree rates #1
      symptoms cipn #1
      skin dermatitis trials #1
      magnesium oxaliplatininduced neurotoxicity #1
      populations neurologic humans #1
      paresthesia peripheral #1
      hormonal ablation andropause #1
      supportive nsclc #1
      doxepin mouthwash patients #1
      hot flash relief #1
      gabapentin aminobutyric acid #1
      bortezomib alters #1
      oxybutynin hot flashes #1
      treatment hot #1
      magnesium camg #1
      cancerassociated anorexia cachexia #1
      udi δ − #1
      recommended colorectal #1
      bakplo placebo #1
      diseases pilot #1
      baseline week gabapentin #1
      cipn20 sensory #1
      hot flash control #1
      hec cisplatin therapy #1
      enoxaparin cvte #1
      cyclohexanols female #1
      efficacy gabapentin #1
      accru study ru221408i #1
      residual hot flashes #1
      differences neuropathy syndromes #1
      ctcae grade #1
      pregenplus #1
      balance gait testing #1
      control hot flashes #1
      patients underdescribers #1
      cinv neoplasms vomiting #1
      device 5 weeks #1
      cipn function #1
      patients spray product #1
      flashes objective #1
      burning pain #1
      gabapentin hot #1
      relatedness treatment #1
      alleviate hot #1
      paps fatigue #1
      female services tpn #1
      cryotherapy hands #1
      active nonhormonal #1
      adjuvant numeracy #1
      data clinical histories #1
      male megestrol megestrol #1
      cipn adult #1
      nonfluid bodyweights #1
      vaginal dehydroepiandrosterone #1
      topical cannabinoids #1
      placebo pilot trials #1
      cryotherapy mucositis #1
      mascc isoo guidelines #1
      hot flash activity #1
      outcomes study points #1
      hormone deprivation #1
      peripheral neuropathy paclitaxel #1
      acute symptoms cycle #1
      ru221408i #1
      therapy hot #1
      neuropathy 20 #1
      cisplatin therapy cinv #1
      patients dosing guidelines #1
      dmc mutations #1
      treatments modalities #1
      bothersome hot #1
      antidepressive agents gamma #1
      fosaprepitant isae #1
      cipnmethodspatients #1
      bothersome hot flashes #1
      paclitaxel study arms #1
      topic rectum surveys #1
      cipn20 questionnaire #1
      1 month appetite #1
      women 65 day #1
      patients highdose interferon #1
      reduction hot #1
      antiserotonergic drug #1
      prestudy hypothesis #1
      n08cb alliance #1
      antidepressant gabapentin #1
      ncctg trial n06ca #1
      topic peripheral neuropathy #1
      hot flash frequency #1
      background hot #1
      burden alopecia #1
      patients nasal vestibulitis #1
      2007 guidelines guideline #1
      purposepaclitaxel #1
      bakplo symptoms #1
      cipn data #1
      attribution treatment #1
      amines antidepressive #1
      inadequate hot #1
      patients 25 micrograms #1
      safety oestrogen #1
      discrepancies women #1
      pilot study minocycline #1
      n08c1 #1
      nonhormonal agent #1
      inadequate control antidepressant #1
      patientreported outcomes balance #1
      cancer anorexia cachexia #1
      physical consequences cipn #1
      neuropathy data #1
      numbness scores #1
      numbness hands #1
      induced neurotoxicity oct2 #1
      supportive cytotoxic chemotherapy #1
      developed mucositis #1
      slight appetite stimulation #1
      women male megestrol #1
      dmc samples #1
      incurable cancer records #1
      eortc cipn #1
      flaxseed hot flashes #1
      placebo arms percentage #1
      ulabtka placebo cream #1
      numbness tingling #1
      ncctg n08c3 #1
      natural postural instability #1
      oral cryotherapy patients #1
      leap 12 months #1
      aes relatedness #1
      resected cutaneous melanomas #1
      discrepancies clinicians assessment #1
      drug humans interferons #1
      shooting burning #1
      purpose hot #1
      adt cyclohexanecarboxylic acids #1
      gene arhgef10 #1
      81 patients patients #1
      n08ca association #1
      placebos pregabalin quality #1
      arthralgia breast life #1
      oral cryotherapy prevention #1
      trust oncologists competence #1
      routine feces sensitivity #1
      illness neuropathic symptoms #1
      cipn postural control #1
      acetate anorexia #1
      neoplasms climacteric #1
      bellergal #1
      5 methylphenidate #1
      women inadequate control #1
      flashes androgen #1
      centrally active agent #1
      antiemetic prescribing #1
      reducing hot #1
      fsfi udi #1
      auc cryotherapy #1
      institutional guidelines patients #1
      antacid mouthwash #1
      alliance n08ca #1
      flashes patients #1
      neoplasm recurrence apixaban #1
      patient followup studies #1
      lenolidamide #1
      nonestrogenic management #1
      effects hot flashes #1
      oral mucositis alopecia #1
      venous toxicity fosaprepitant #1
      tpn death #1
      5 weeks device #1
      cachexia carcinoma life #1
      1year survival trials #1
      testosterone improvements #1
      udi scores baseline #1
      pilot trials citalopram #1
      treating institution intervention #1
      95 doxepin mouthwash #1
      prevent oxaliplatin #1
      2007 guidelines suggestion #1
      deprivation therapy patients #1
      extensive animal data #1
      progestational agents patients #1
      grade peripheral neuropathy #1
      or1 year patients #1
      effects cipn #1
      pilot trials venlafaxine #1
      dronabinol combination #1
      flashes pilot #1
      nonhormonal agents treatment #1
      neuropathic symptoms breast #1
      records adult patients #1
      cipn nervous diseases #1
      bakplo #1
      motor subscales #1
      methylphenidate cancer patients #1
      oncologists competence 95ci #1
      lymphedema incidence intervention #1
      individual patients understanding #1
      cipn trials #1
      purposehot #1
      purposehot flashes #1
      infliximab lung #1
      cipn development severity #1
      improvements hot flashes #1
      revisitation doc #1
      acceptability ssc device #1
      cipn20 #1
      daily hot #1
      mouthwash placebo #1
      − fsfi #1
      patients gabapentin #1
      hot flash mechanism #1
      snv rs9657362 #1
      conducted studies hrt #1
      balance impairments patients #1
      trial n00cb #1
      nonhormonal hot #1
      pregabalin paps #1
      prognosis items #1
      alleviating hot #1
      ambulatory patients opioids #1
      cipn20 data #1
      lymphedema hrqol outcomes #1
      regional hypothermia burden #1
      attribution percentage #1
      nonfluid weight gain #1
      baseline prognosis #1
      authors 115 patients #1
      induced cipn #1
      subsequent chemotherapy cycles #1
      response relationship odc #1
      gabapentin arm #1
      antibiotic lozenge placebo #1
      humans ganglion surveys #1
      cinv day #1
      suggested gabapentin #1
      coasting phenomenon #1
      mouthwash diphenhydramine #1
      crc patients 95 #1
      prevention paps #1
      score baseline values #1
      neuropathy prevention #1
      cipnsummarythere #1
      cachexia trial #1
      cachexia dexamethasone #1
      rs2294039 #1
      5fuinduced ocular toxicity #1
      treating hot #1
      anecdotal observations #1
      cyproheptadine appetite #1
      cipn methods #1
      lignans 6 weeks #1
      oestrogen hot flashes #1
      megestrol acetate patients #1
      patients ulabtka #1
      tools hypothetical scenarios #1
      cipn common #1
      pilot trial hands #1
      tpn longterm survival #1
      flaxseed bar lignans #1
      gsm fsfi #1
      ssc device prototype #1
      cachexia cyproheptadine #1
      alliance a151724 #1
      agents antihypertensive agents #1
      patients dfs predictions #1
      subcutaneous testosterone improvements #1
      treatment hot flashes #1
      polyneuropathy allelic variability #1
      understanding potential benefits #1
      current trial #1
      data hot #1
      managing hot #1
      dmc assay #1
      based chemotherapy isae #1
      leap lymphedema #1
      baseline prognosis values #1
      gabapentin baseline week #1
      flash therapies #1
      weeks hot flashes #1
      patients subcutaneous testosterone #1
      flaxseed bar #1
      paclitaxel polyneuropathy #1
      toxicity anecdotal observations #1
      dronabinol megestrol acetate #1
      prominent clinical problem #1
      patients 10 range #1
      oestrogen survivors #1
      association arhgef10 #1
      flash scores #1
      flashes prostate #1
      hot flashes #1
      recurrences clinical histories #1
      minocycline cipn #1
      management hot flashes #1
      therapeutic targets cipn #1
      rs17683288 #1
      cachexia megestrol #1
      difference cipn20 scores #1
      numerical analogue scale #1
      flashes treatment #1
      doxepin mouthwash #1
      hot flash #1
      established cipn #1
      placebo 15 points #1
      alopecia ocular toxicity #1
      taxane infusion #1
      randomized study lymphedema #1
      gabapentin hot flashes #1
      hfs trial #1
      baseline assessment week #1
      neuropathy randomized #1
      placebo drowsiness #1
      stomatitis scores #1
      breakthrough nausea patients #1
      doubleblinded manner #1
      flashes week #1
      weeks hot #1
      attribution clinical trials #1
      taxane treatment development #1
      hours nighttime sleep #1
      diphenhydraminelidocaineantacid #1
      vte recurrence enoxaparin #1
      study dmc assay #1
      pain chemotherapy #1
      flashes women #1
      head therapeutic equivalency #1
      ulabtka #1
      baseline week followup #1
      n01c9 #1
      rs9657362 previous study #1
      women megestrol acetate #1
      hormone deprivation symptoms #1
      therapy numbness #1
      tpn female services #1
      lymphedemafree rates groups #1
      2 study arms #1
      receiving fluorouracil #1
      overview oncology providers #1
      oncologists competence #1
      suggestion pregabalin #1
      dfs predictions adjuvant #1
      cryotherapy auc #1
      fractures infertility #1
      95 increased difficulty #1
      95 neuropathic pain #1
      chemotherapy neuropathy #1
      studies cyproheptadine #1
      life megestrol acetate #1
      favor placebo #1
      vaginal dehydroepiandrosterone dhea #1
      paclitaxel acute #1
      day cisplatin therapy #1
      intervention leap #1
      8week observation period #1
      acetate appetite #1
      prevention oral cryotherapy #1
      tpn initiation death #1
      5fu adjuvant #1
      anorexia antineoplastic agents #1
      n08ca patients #1
      22 nonestrogenic management #1
      hot flash scores #1
      phytotherapy vitamin #1
      toxicity ocular #1
      patients physical examinations #1
      severe stomatitis #1
      difficulty neuropathic pain #1
      life qlqcipn20 #1
      gas menopause patient #1
      hfs ulabtka #1
      qlq cipn20 #1
      management genital symptoms #1
      vitamin cipn #1
      30 points 95 #1
      anorexia appetite #1
      baseline neuropathic pain #1
      12 months anticoagulation #1
      altered sensory organization #1
      qol reported difficulty #1
      leucovorin breast cancer #1
      bridging editorial #1
      estimated benefit dfs #1
      baseline fsfi score #1
      loe prevention #1
      hfs symptoms patients #1
      papsmethodspatients #1
      alliance study a221102 #1
      flashes stellate #1
      gabapentin antidepressant #1
      antineoplastic agents nrs #1
      43 oral complications #1
      preliminary evidence improvement #1
      accru trial #1
      toxicity gabapentin #1
      patients hot flashes #1
      longitudinal continuation #1
      cachexia studies #1
      placebo mouthwash #1
      middle aged minocycline #1
      chamomile mouthwash toxicity #1
      backgrounddehydroepiandrosterone #1
      symptoms feet #1
      duloxetine response #1
      megestrol acetate nausea #1
      acetate dexamethasone #1
      education lymphedema education #1
      hot flashes women #1
      isae anthracycline #1
      tingling numbness #1
      preliminary promising data #1
      week hot #1
      uniscale qol baseline #1
      alliance trial #1
      symptoms hands #1
      oncology providers crci #1
      individuals impaired balance #1
      cachexia cancer anorexia #1
      acetate doses #1
      20 data patients #1
      nsclc response rate #1
      cipn paps #1
      isaes #1
      compassionate honesty #1
      cyclohexanecarboxylic acids gamma #1
      cvte rivaroxaban #1
      fluoxetine hot #1
      ocular ice #1
      tested interventions lymphedema #1
      joints syndrome #1
      toxicity prospective trial #1
      paclitaxel coasting phenomenon #1
      survivors genitourinary syndrome #1
      cipn phase iii #1
      mascc isoo evidence #1
      acute pain syndrome #1
      qolresultsfrom #1
      n06ca #1
      hot flashes treatment #1
      postsurgical neuropathic pain #1
      sensory neuropathy symptoms #1
      acetate versus #1
      underdescribing #1
      rest psychostimulants #1
      nonhormonal therapies paroxetine #1
      cancer hot #1
      antibiotic lozenge #1
      balance patientreported outcomes #1
      aimss life #1
      flashes common #1
      prtmethodsdata #1
      hot flashes quality #1
      overview crci #1
      pilot evaluation #1
      ulabtka arm #1
      chamomile mouthwash #1
      male megestrol life #1
      cipn agents #1
      feet oxaliplatin #1
      oncologists prognostic #1
      placebo arm gabapentin #1
      hot flashes acceptability #1
      week tamoxifen #1
      hot flash score #1
      isae data #1
      ncctg n08c1 #1
      5fuinduced stomatitis #1
      nonhormonal agents #1
      guidelineendorsed treatment #1
      aminobutyric acid hec #1
      placebo oxybutynin doses #2
      worse survivorship #2
      15 points 95 #2
      conceppt #2
      study arms #2
      n03cb #2
      tamoxifenassociated hot flashes #2
      ductal mometasone furoate #2
      cipn prevention trials #2
      sdt1 hemoccult #2
      irox folfox auc #2
      432 smokers treatment #2
      treatment cycles cycle #2
      nonhormonal management #2
      anthraquinones agents breast #2
      life scrambler therapy #2
      120000 epoetin alfa #2
      leucovorin women #2
      oxaliplatin hands #2
      substantial hot flashes #2
      neuropathy paclitaxel #2
      tens global impression #2
      prevent paclitaxel #2
      stage disease 5fu #2
      descriptive manner #2
      tamoxifen percentage reduction #2
      3 months bupropion #2
      evaluate weight #2
      day baseline week #2
      hemoccultsensa sensitivity #2
      improvement hot flashes #2
      data gabapentin #2
      cipn antineoplastic agents #2
      hot flash trials #2
      flash studies #2
      treatment arm mmf #2
      induced arthralgias #2
      cisplatin polymerase inhibitors #2
      mometasone time #2
      positive doseresponse #2
      advanced cancer anorexia #2
      sdt2 hemoccult #2
      trial suggestion #2
      treatment smoking abstinence #2
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      manuscript “use #2
      vte recurrence doacs #2
      cohosh treatment #2
      topical aged antimetabolites #2
      95 oral placebo #2
      megestrol acetate dexamethasone #2
      allopurinol mouthwash #2
      previous hot flashes #2
      middle aged survivors #2
      study arms quality #2
      paclitaxel induced #2
      nutrition scores 95 #2
      time ncctg alliance #2
      dhea 4 weeks #2
      acknowledged loss #2
      symptoms skin toxicity #2
      anabolic corticosteroid #2
      duloxetine hydrochloride humans #2
      placebo arms women #2
      data relative benefits #2
      hot flashes pregabalin #2
      participants 3 stools #2
      infliximab 5 day #2
      venlafaxine treatment 75 #2
      hot flash frequencies #2
      infertility ovarian failure #2
      4 treatment weeks #2
      patients difluoromethylornithine #2
      cycle chronic neurotoxicity #2
      induced peripheral #2
      chemotherapy peripheral neuropathy #2
      original report time #2
      pilocarpine vaginal dryness #2
      lmwh arms #2
      anthrapyrazoles piroxantrone #2
      study treatment citalopram #2
      neuropathy cipn #2
      piroxantrone women #2
      illness tetracycline egfr #2
      rcts preventive therapies #2
      symptomatic cipn #2
      reduce hot #2
      incidence severity stomatitis #2
      pilocarpine arms #2
      symptoms surveys #2
      oral megestrol #2
      flashes citalopram #2
      hot flashes citalopram #2
      skindex16 ctcae #2
      fatigue improvement methylphenidate #2
      evaluating venlafaxine #2
      week breast cancer #2
      01 mmf #2
      screenrelevant neoplasms 16 #2
      guaninemethyltransferase #2
      folfox alliance #2
      108±11 #2
      hot flashes dehydroepiandrosterone #2
      tingling shooting #2
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      single snv #2
      treatment breakthrough cinv #2
      levetiracetam 4 weeks #2
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      120 arm #2
      treating chemotherapy #2
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      multiple #27050
      follow studies #27065
      polymorphism single #27142
      united #27151
      histologically #27323
      inherited #27404
      neoplasm proteins #27717
      prognosis retrospective #27768
      systematic #27775
      functional #27808
      0005 #28001
      predisposition #28007
      preoperative #28036
      skeletal #28185
      longitudinal #28189
      estimated #28229
      leads #28238
      missing #28264
      acid #28356
      anti inflammatory #28360
      correlate #28365
      larger #28581
      sex factors #28629
      causing #28688
      sensitivity #28740
      vary #28851
      11 #28869
      matched #28979
      represents #29258
      detection #29343
      active #29413
      differentiate #29510
      objectives #29543
      completely #29721
      factual #29750
      databases factual #29793
      varied #30036
      excluded #30077
      quantified #30091
      occurs #30143
      adjusted #30189
      logistic #30241
      underlying #30508
      allowed #30520
      national #30765
      odds #30909
      001 #30996
      regression #31005
      unchanged #31053
      separately #31068
      characterize #31283
      recombinant #31415
      adolescent #31473
      dose dependent #31787
      age #31875
      lacking #31939
      attenuated #31971
      lower #32078
      correlated #32273
      postoperative #32309
      negative #32666
      growth factor #33089
      positive #33861
      understood #33957
      confirmed #33982
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      implicated #34054
      confidence #34153
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      requires #35112
      directly #35347
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      suggesting #37604
      remains #37899
      multivariate #38132
      independent #38886
      measured #38991
      proto oncogene #39186
      proto #39814
      biomarkers tumor #39899
      examined #40295
      retrospective studies #42973
      underwent #43365
      95 confidence #44196

       

      Prominent publications by Charles L Loprinzi

      KOL-Index: 16482

      Importance: Zoledronic acid, a third-generation aminobisphosphonate, reduces the incidence of skeletal-related events and pain in patients with bone metastases. The optimal dosing interval for zoledronic acid is uncertain.

      Objective: To determine whether zoledronic acid administered every 12 weeks is noninferior to zoledronic acid administered every 4 weeks.

      Design, Setting, Participants: Randomized, open-label clinical trial conducted at 269 academic and community sites in the United ...

      Bekannt für Zoledronic Acid | Bone Metastases | 2 Years | Patients Breast Cancer | Skeletal Events
      KOL-Index: 16399

      Postmenopausal women with breast cancer (BC) are at increased risk for bone loss. Bisphosphonates improve bone mineral density (BMD) in normal postmenopausal women. The purpose of this study was to determine if immediate treatment with zoledronic acid preserves BMD in postmenopausal women with BC starting letrozole after tamoxifen. Postmenopausal women with BC completing tamoxifen were treated with daily letrozole 2.5 mg/vitamin D 400 I.U., calcium 500 mg twice daily and were randomized ...

      Bekannt für Postmenopausal Women | Bone Loss | Zoledronic Acid | Breast Cancer | Versus Delayed
      KOL-Index: 13693

      PURPOSE: Risedronate prevents bone loss in postmenopausal women. The purpose of this study was to determine whether risedronate prevents bone loss in premenopausal women undergoing chemotherapy for breast cancer.

      PATIENTS AND METHODS: Premenopausal women undergoing chemotherapy for breast cancer were treated with oral calcium 600 mg and vitamin D 400 U daily and randomly assigned to receive oral risedronate 35 mg weekly or placebo, with all these therapies beginning within a month of the ...

      Bekannt für Bone Loss | Premenopausal Women | Breast Cancer | 1 Year | Bmd Baseline
      KOL-Index: 13389

      BACKGROUND: Cisplatin is primarily used for treatment of ovarian and testicular cancer. Oxaliplatin is the only effective treatment for metastatic colorectal cancer. Both are known to cause dose related, cumulative toxic effects on the peripheral nervous system and thirty to forty percent of cancer patients receiving these agents experience painful peripheral neuropathy. The mechanisms underlying painful platinum-induced neuropathy remain poorly understood. Previous studies have ...

      Bekannt für Trpv1 Trpa1 | Transient Receptor | Cisplatin Oxaliplatin | Mechanical Allodynia | Treated Mice
      KOL-Index: 13187

      PURPOSE: Functional iron deficiency may impair response to erythropoiesis-stimulating agents (ESAs) in iron-replete patients with chemotherapy-associated anemia (CAA). This study evaluated whether coadministration of parenteral iron improves ESA efficacy in patients with CAA.

      PATIENTS AND METHODS: This prospective, multicenter, randomized trial enrolled 502 patients with hemoglobin (Hb) less than 11 g/dL who were undergoing chemotherapy for nonmyeloid malignancies. All patients received ...

      Bekannt für Oral Iron | Darbepoetin Alfa | Erythropoietic Response | Phase Iii | Ferric Gluconate
      KOL-Index: 12870

      To develop a framework for the definition and classification of cancer cachexia a panel of experts participated in a formal consensus process, including focus groups and two Delphi rounds. Cancer cachexia was defined as a multifactorial syndrome defined by an ongoing loss of skeletal muscle mass (with or without loss of fat mass) that cannot be fully reversed by conventional nutritional support and leads to progressive functional impairment. Its pathophysiology is characterised by a ...

      Bekannt für Cancer Cachexia | International Consensus | Definition Classification | Weight Loss | Reduced Food Intake
      KOL-Index: 12824

      PURPOSE: Although it is well-established that fluorouracil- (FU-) based adjuvant therapy improves survival for patients with resected high-risk colon cancer, the magnitude of adjuvant therapy benefit across specific subgroups and for individual patients has been uncertain.

      PATIENTS AND METHODS: Using a pooled data set of 3,302 patients with stage II and III colon cancer from seven randomized trials comparing FU + leucovorin or FU + levamisole to surgery alone, we performed an analysis ...

      Bekannt für Adjuvant Therapy | Nodal Status | Colon Cancer | Survival Stage | Pooled Analysis
      KOL-Index: 12701

      OBJECTIVE: To compare the combination of a nicotine inhaler and bupropion to either treatment alone for initiating smoking abstinence and relapse prevention.

      METHODS: Smokers were randomized to receive a nicotine inhaler, bupropion, or both for 3 months. At 3 months, smoking-abstinent study participants were randomized to their initial medications or placebo. Participants who were smoking at 3 months were randomized to an alternative treatment regimen or placebo. This study was conducted ...

      Bekannt für Relapse Prevention | Nicotine Inhaler | Bupropion Placebo | Smoking Abstinence | Treatment Phase
      KOL-Index: 12639

      BACKGROUND: Experimental studies in animals and observational studies in humans suggest that regular aspirin use may decrease the risk of colorectal adenomas, the precursors to most colorectal cancers.

      METHODS: We conducted a randomized, double-blind trial to determine the effect of aspirin on the incidence of colorectal adenomas. We randomly assigned 635 patients with previous colorectal cancer to receive either 325 mg of aspirin per day or placebo. We determined the proportion of ...

      Bekannt für Colorectal Adenomas | Patients Aspirin | Observational Studies | Relative Risks | Cancer Adenoma
      KOL-Index: 12619

      BACKGROUND: Stool DNA testing is a new approach to colorectal cancer detection. Few data are available from the screening setting.

      OBJECTIVE: To compare stool DNA and fecal blood testing for detection of screen-relevant neoplasia (curable-stage cancer, high-grade dysplasia, or adenomas >1 cm).

      DESIGN: Blinded, multicenter, cross-sectional study.

      SETTING: Communities surrounding 22 participating academic and regional health care systems in the United States.

      PARTICIPANTS: 4482 ...

      Bekannt für Stool Dna | Blood Test | Screen Detection | Colorectal Neoplasia | Humans Specificity
      KOL-Index: 12464

      PURPOSE: Recent changes have occurred in the presurgical planning for breast cancer, including the introduction of preoperative breast magnetic resonance imaging (MRI). We sought to analyze the trends in mastectomy rates and the relationship to preoperative MRI and surgical year at Mayo Clinic, Rochester, MN.

      PATIENTS AND METHODS: We identified 5,405 patients who underwent surgery between 1997 and 2006. Patients undergoing MRI were identified from a prospective database. Trends in ...

      Bekannt für Mastectomy Rates | Magnetic Resonance | Patients Mri | Surgery Type | Surgical Year
      KOL-Index: 12354

      PURPOSE: Previous double-blind, placebo-controlled, randomized clinical trials have demonstrated that both corticosteroids and progestational agents do partially alleviate cancer anorexia/cachexia. Pilot information suggested that an anabolic corticosteroid might also improve appetite in patients with cancer anorexia/cachexia. The current trial was developed to compare and contrast a progestational agent, a corticosteroid, and an anabolic corticosteroid for the treatment of cancer ...

      Bekannt für Cancer Anorexia | Megestrol Acetate | Cachexia Patients | Progestational Agents | Corticosteroid Treatment
      KOL-Index: 12321

      BACKGROUND: Vasomotor hot flashes are a common symptom in women during menopause and in men who have undergone androgen-deprivation therapy for prostate cancer. Although treatment with estrogens in women and androgens in men can attenuate these symptoms, these hormones may be contraindicated in women with breast cancer and in men with prostate cancer. Pilot trials have suggested that the progestational agent megestrol acetate can ameliorate hot flashes in both groups of ...

      Bekannt für Megestrol Acetate | Hot Flashes | Women Breast Cancer | Deprivation Therapy | Weeks Placebo

      Schlüsselpersonen für Hot Flashes

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      Charles L Loprinzi
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      Charles L Loprinzi:Expertenwirkung

      Konzepte für welcheCharles L Loprinzihat direkten Einfluss:Hot flashes,  Breast cancer,  Megestrol acetate,  Peripheral neuropathy,  Scrambler therapy,  Phase iii,  Newer antidepressants,  Hot flash.

      Charles L Loprinzi:KOL -Auswirkungen

      Konzepte im Zusammenhang mit der Arbeit anderer Autoren, für diefor which Charles L Loprinzi hat Einfluss:Breast cancer,  Hot flashes,  Adjuvant chemotherapy,  Quality life,  Weight loss,  Oral mucositis,  Neuropathic pain.


       

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      Mayo Clinic, Rochester, MN; | Division of Medical Oncology, Mayo Clinic, Rochester, MN 55902, USA;, cloprinzi@mayo.edu | Department of Oncology, Mayo Clinic, Rochester, MN 55905, United States. Electronic address: cloprinzi@mayo.edu. | Mayo Clinic, R

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