• KOL
    • Charles L Loprinzi
    • Charles L Loprinzi

      Charles L Loprinzi

      Mayo Clinic, Rochester, MN; | Division of Medical Oncology, Mayo Clinic, Rochester, MN 55902, USA;, cloprinzi@mayo.edu | Department of Oncology, Mayo Clinic, Rochester, MN ...

       

       

      Kol melanjutkan untuk Charles L Loprinzi

      Year
      2022

      Mayo Clinic, Rochester, MN;

      2021

      Department of Oncology, Mayo Clinic, Rochester, MN 55905, United States. Electronic address:

      Mayo Clinic, Rochester, MN, USA

      2020

      Department of Oncology, Mayo Clinic Comprehensive Cancer Center, Rochester, United States of America

      Division of Medical Oncology, Mayo Clinic, Rochester, USA

      North Central Cancer Treatment Group, Mayo Clinic, Rochester, Minnesota

      Mayo Clinic, Rochester, MN, United States.

      2019

      Department of Oncology; Mayo Clinic; Rochester, Minnesota

      Mayo Clinic Rochester, Florida, USA

      Medical Oncology

      2018

      Department of Medical Oncology, Mayo Clinic, 200 First St SW, 55905, Rochester, MN, USA

      Division of Medical Oncology, Mayo Clinic, Rochester, MN

      2017

      Division of Medical Oncology, Mayo Clinic, Rochester, MN.

      Timothy Gilligan, Cleveland Clinic, Cleveland, OH ; Nessa Coyle, Memorial Sloan Kettering Cancer Center, New York; Ronald M. Epstein, University of Rochester School of Medicine, Rochester, NY; Richard M. Frankel, Regenstrief Institute, Indiana University School of Medicine, Indianapolis, IN; Donna L. Berry and Christopher S. Lathan, Dana-Farber Cancer Institute, Harvard Medical School; Vicki A. Jackson, Massachusetts General Hospital, Harvard Medical School, Boston; Carole Seigel, Patient/Advocacy Representative, Brookline, MA; Kari Bohlke, American Society of Clinical Oncology, Alexandria, VA; Esme Finlay, University of New Mexico School of Medicine, Albuquerque, NM; Charles L. Loprinzi, Mayo Clinic, Rochester, MN; and Lynne H. Nguyen and Walter F. Baile, The University of Texas MD Anderson Cancer Center, Houston, TX.

      Mayo Clinic Minnesota Department of Oncology Rochester Minnesota

      The Cancer Center

      2016

      Alliance Statistics and Data Center, Mayo Clinic (R.Q., H.L.), and Mayo Clinic (K.J.R., J.M.L., C.L.L.), Rochester, MN

      Mayo Clinic Cancer Center, Rochester, Minnesota

      2015

      Departments of Neurology, Oncology, Health Sciences Research, Division of Biomedical Statistics and Informatics, Mayo Clinic College of Medicine, Rochester, MN, USA

      Mayo Clinic Division of Medical Oncology Rochester Minnesota

      2014

      Mayo Clinic Cancer Center Rochester MN

      2013

      From the Department of Oncology and Cancer Center Statistics, Mayo Clinic, Rochester, MN.

      Mayo Clinic Rochester, 200 First Street, SW, 55905, Rochester, MN, USA

      2012

      Department of Oncology, Mayo Clinic, 55905, Rochester, MN, USA

      Mayo Clinic, Rochester, MN, United States

       

       

      Charles L Loprinzi: Statistik pengaruh

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      multiple #27050
      follow studies #27065
      polymorphism single #27142
      united #27151
      histologically #27323
      inherited #27404
      neoplasm proteins #27717
      prognosis retrospective #27768
      systematic #27775
      functional #27808
      0005 #28001
      predisposition #28007
      preoperative #28036
      skeletal #28185
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      missing #28264
      acid #28356
      anti inflammatory #28360
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      sex factors #28629
      causing #28688
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      vary #28851
      11 #28869
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      detection #29343
      active #29413
      differentiate #29510
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      completely #29721
      factual #29750
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      varied #30036
      excluded #30077
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      occurs #30143
      adjusted #30189
      logistic #30241
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      001 #30996
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      characterize #31283
      recombinant #31415
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      dose dependent #31787
      age #31875
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      attenuated #31971
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      correlated #32273
      postoperative #32309
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      growth factor #33089
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      proto oncogene #39186
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      examined #40295
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      underwent #43365
      95 confidence #44196

       

      Prominent publications by Charles L Loprinzi

      KOL-Index: 16482

      Importance: Zoledronic acid, a third-generation aminobisphosphonate, reduces the incidence of skeletal-related events and pain in patients with bone metastases. The optimal dosing interval for zoledronic acid is uncertain.

      Objective: To determine whether zoledronic acid administered every 12 weeks is noninferior to zoledronic acid administered every 4 weeks.

      Design, Setting, Participants: Randomized, open-label clinical trial conducted at 269 academic and community sites in the United ...

      Dikenal sebagai Zoledronic Acid | Bone Metastases | 2 Years | Patients Breast Cancer | Skeletal Events
      KOL-Index: 16399

      Postmenopausal women with breast cancer (BC) are at increased risk for bone loss. Bisphosphonates improve bone mineral density (BMD) in normal postmenopausal women. The purpose of this study was to determine if immediate treatment with zoledronic acid preserves BMD in postmenopausal women with BC starting letrozole after tamoxifen. Postmenopausal women with BC completing tamoxifen were treated with daily letrozole 2.5 mg/vitamin D 400 I.U., calcium 500 mg twice daily and were randomized ...

      Dikenal sebagai Postmenopausal Women | Bone Loss | Zoledronic Acid | Breast Cancer | Versus Delayed
      KOL-Index: 13693

      PURPOSE: Risedronate prevents bone loss in postmenopausal women. The purpose of this study was to determine whether risedronate prevents bone loss in premenopausal women undergoing chemotherapy for breast cancer.

      PATIENTS AND METHODS: Premenopausal women undergoing chemotherapy for breast cancer were treated with oral calcium 600 mg and vitamin D 400 U daily and randomly assigned to receive oral risedronate 35 mg weekly or placebo, with all these therapies beginning within a month of the ...

      Dikenal sebagai Bone Loss | Premenopausal Women | Breast Cancer | 1 Year | Bmd Baseline
      KOL-Index: 13389

      BACKGROUND: Cisplatin is primarily used for treatment of ovarian and testicular cancer. Oxaliplatin is the only effective treatment for metastatic colorectal cancer. Both are known to cause dose related, cumulative toxic effects on the peripheral nervous system and thirty to forty percent of cancer patients receiving these agents experience painful peripheral neuropathy. The mechanisms underlying painful platinum-induced neuropathy remain poorly understood. Previous studies have ...

      Dikenal sebagai Trpv1 Trpa1 | Transient Receptor | Cisplatin Oxaliplatin | Mechanical Allodynia | Treated Mice
      KOL-Index: 13187

      PURPOSE: Functional iron deficiency may impair response to erythropoiesis-stimulating agents (ESAs) in iron-replete patients with chemotherapy-associated anemia (CAA). This study evaluated whether coadministration of parenteral iron improves ESA efficacy in patients with CAA.

      PATIENTS AND METHODS: This prospective, multicenter, randomized trial enrolled 502 patients with hemoglobin (Hb) less than 11 g/dL who were undergoing chemotherapy for nonmyeloid malignancies. All patients received ...

      Dikenal sebagai Oral Iron | Darbepoetin Alfa | Erythropoietic Response | Phase Iii | Ferric Gluconate
      KOL-Index: 12870

      To develop a framework for the definition and classification of cancer cachexia a panel of experts participated in a formal consensus process, including focus groups and two Delphi rounds. Cancer cachexia was defined as a multifactorial syndrome defined by an ongoing loss of skeletal muscle mass (with or without loss of fat mass) that cannot be fully reversed by conventional nutritional support and leads to progressive functional impairment. Its pathophysiology is characterised by a ...

      Dikenal sebagai Cancer Cachexia | International Consensus | Definition Classification | Weight Loss | Reduced Food Intake
      KOL-Index: 12824

      PURPOSE: Although it is well-established that fluorouracil- (FU-) based adjuvant therapy improves survival for patients with resected high-risk colon cancer, the magnitude of adjuvant therapy benefit across specific subgroups and for individual patients has been uncertain.

      PATIENTS AND METHODS: Using a pooled data set of 3,302 patients with stage II and III colon cancer from seven randomized trials comparing FU + leucovorin or FU + levamisole to surgery alone, we performed an analysis ...

      Dikenal sebagai Adjuvant Therapy | Nodal Status | Colon Cancer | Survival Stage | Pooled Analysis
      KOL-Index: 12701

      OBJECTIVE: To compare the combination of a nicotine inhaler and bupropion to either treatment alone for initiating smoking abstinence and relapse prevention.

      METHODS: Smokers were randomized to receive a nicotine inhaler, bupropion, or both for 3 months. At 3 months, smoking-abstinent study participants were randomized to their initial medications or placebo. Participants who were smoking at 3 months were randomized to an alternative treatment regimen or placebo. This study was conducted ...

      Dikenal sebagai Relapse Prevention | Nicotine Inhaler | Bupropion Placebo | Smoking Abstinence | Treatment Phase
      KOL-Index: 12639

      BACKGROUND: Experimental studies in animals and observational studies in humans suggest that regular aspirin use may decrease the risk of colorectal adenomas, the precursors to most colorectal cancers.

      METHODS: We conducted a randomized, double-blind trial to determine the effect of aspirin on the incidence of colorectal adenomas. We randomly assigned 635 patients with previous colorectal cancer to receive either 325 mg of aspirin per day or placebo. We determined the proportion of ...

      Dikenal sebagai Colorectal Adenomas | Patients Aspirin | Observational Studies | Relative Risks | Cancer Adenoma
      KOL-Index: 12619

      BACKGROUND: Stool DNA testing is a new approach to colorectal cancer detection. Few data are available from the screening setting.

      OBJECTIVE: To compare stool DNA and fecal blood testing for detection of screen-relevant neoplasia (curable-stage cancer, high-grade dysplasia, or adenomas >1 cm).

      DESIGN: Blinded, multicenter, cross-sectional study.

      SETTING: Communities surrounding 22 participating academic and regional health care systems in the United States.

      PARTICIPANTS: 4482 ...

      Dikenal sebagai Stool Dna | Blood Test | Screen Detection | Colorectal Neoplasia | Humans Specificity
      KOL-Index: 12464

      PURPOSE: Recent changes have occurred in the presurgical planning for breast cancer, including the introduction of preoperative breast magnetic resonance imaging (MRI). We sought to analyze the trends in mastectomy rates and the relationship to preoperative MRI and surgical year at Mayo Clinic, Rochester, MN.

      PATIENTS AND METHODS: We identified 5,405 patients who underwent surgery between 1997 and 2006. Patients undergoing MRI were identified from a prospective database. Trends in ...

      Dikenal sebagai Mastectomy Rates | Magnetic Resonance | Patients Mri | Surgery Type | Surgical Year
      KOL-Index: 12354

      PURPOSE: Previous double-blind, placebo-controlled, randomized clinical trials have demonstrated that both corticosteroids and progestational agents do partially alleviate cancer anorexia/cachexia. Pilot information suggested that an anabolic corticosteroid might also improve appetite in patients with cancer anorexia/cachexia. The current trial was developed to compare and contrast a progestational agent, a corticosteroid, and an anabolic corticosteroid for the treatment of cancer ...

      Dikenal sebagai Cancer Anorexia | Megestrol Acetate | Cachexia Patients | Progestational Agents | Corticosteroid Treatment
      KOL-Index: 12321

      BACKGROUND: Vasomotor hot flashes are a common symptom in women during menopause and in men who have undergone androgen-deprivation therapy for prostate cancer. Although treatment with estrogens in women and androgens in men can attenuate these symptoms, these hormones may be contraindicated in women with breast cancer and in men with prostate cancer. Pilot trials have suggested that the progestational agent megestrol acetate can ameliorate hot flashes in both groups of ...

      Dikenal sebagai Megestrol Acetate | Hot Flashes | Women Breast Cancer | Deprivation Therapy | Weeks Placebo

      Orang -orang kunci untuk Hot Flashes

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      Charles L Loprinzi
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      Charles L Loprinzi:Dampak ahli

      Konsep yang manaCharles L Loprinzimemiliki pengaruh langsung:Hot flashes,  Breast cancer,  Megestrol acetate,  Peripheral neuropathy,  Scrambler therapy,  Phase iii,  Newer antidepressants,  Hot flash.

      Charles L Loprinzi:Dampak Kol

      Konsep yang terkait dengan karya penulis lain yang manafor which Charles L Loprinzi memiliki pengaruh:Breast cancer,  Hot flashes,  Adjuvant chemotherapy,  Quality life,  Weight loss,  Oral mucositis,  Neuropathic pain.


       

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      Mayo Clinic, Rochester, MN; | Division of Medical Oncology, Mayo Clinic, Rochester, MN 55902, USA;, cloprinzi@mayo.edu | Department of Oncology, Mayo Clinic, Rochester, MN 55905, United States. Electronic address: cloprinzi@mayo.edu. | Mayo Clinic, R

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