Prominent publications by Teresa Marie Darragh

KOL Index score: 18485

An association between erythema multiforme and herpes simplex virus infection has been supported by clinical studies and by the detection by immunofluorescence of herpes viral antigen in sera and skin biopsy specimens of patients with erythema multiforme. In rare cases, the virus has also been isolated in cultures of skin biopsy specimens of erythema multiforme. To investigate further the association between erythema multiforme and herpes simplex virus, we used the polymerase chain ...

Known for Simplex Virus |  Erythema Multiforme |  Polymerase Chain Reaction |  Viral Dna |  Skin Lesions
KOL Index score: 18269

OBJECTIVES: To study anal intraepithelial neoplasia and its associations with anal and cervical human papillomavirus (HPV), cervical neoplasia, host immune status, and demographic and behavioral risk factors in women with and at risk for HIV infection.

DESIGN: Point-prevalence analysis nested within a prospective study of women seen at three clinical centers of the Women's Interagency HIV Study.

METHODS: In 2001-2003 participants were interviewed, received a gynecological examination, ...

Known for Anal Intraepithelial |  Infected Women |  Risk Hiv |  Cervical Neoplasia |  Multisite Study
KOL Index score: 16007

CONTEXT: Low-grade squamous intraepithelial lesions (LSILs) have been described as a benign cytological consequence of active human papillomavirus (HPV) replication. Several studies have reported that certain behavioral and biological risks exist for LSIL, suggesting that HPV alone is not sufficient for the development of LSIL. However, because most of these studies have been cross-sectional, it is not known whether behavioral and biological risks are simply risks for HPV infection ...

Known for Papillomavirus Infection |  Young Females |  Lsil Hpv |  Sexual Behavior |  Grade Squamous
KOL Index score: 15451

PURPOSE: High-resolution anoscopy is colposcopy of the anus after applying 3 percent acetic acid. High-resolution anoscopy with biopsy was used as the standard for detecting high-grade anal neoplasia and was compared to detection of high-grade anal neoplasia by anal cytology, human papillomavirus testing, or the combination.

METHODS: A total of 125 men who have sex with men (MSM) were enrolled from a group of MSM identified by random digit dialing: HIV-negative = 85, HIV-positive = 35, ...

Known for Grade Anal |  Resolution Anoscopy |  Human Papillomavirus Testing |  Performance Characteristics |  Sensitivity Specificity
KOL Index score: 14902

BACKGROUND: Anal cancers are thought to arise from squamous intraepithelial lesions in the anal canal, and women infected with human immunodeficiency virus-1 (HIV) may be at higher risk of anal cancer. Our aim was to determine the prevalence of human papillomavirus (HPV)-related abnormalities of the anal canal in women and to characterize risk factors for these lesions.

METHODS: We evaluated HPV-related abnormalities in 251 HIV-positive and in 68 HIV-negative women. We completed physical ...

Known for Anal Squamous |  Intraepithelial Lesions |  Women Hiv |  Risk Abnormal |  Human Immunodeficiency
KOL Index score: 14744

BACKGROUND: Human papillomavirus (HPV) infection of the cervix and related abnormal cervical cytology in HIV-infected women has been well described. Little is known about anal HPV infection in HIV-infected women.

METHODS: The SUN Study is a prospective cohort study of 700 HIV-infected patients including 167 women. At baseline, patients completed a behavioral questionnaire and provided, among other samples, cervical and anal swabs for HPV detection and genotyping and for cytologic ...

Known for Sun Study |  Infected Women |  Human Papillomavirus |  Anus Cervix |  Abnormal Anal Cytology
KOL Index score: 14596

OBJECTIVES: The objectives of this study were to describe the early natural history of human papillomavirus (HPV) infection by examining a cohort of young women positive for an HPV test and to define within this cohort (1) the probability of HPV regression, (2) the risk of having a squamous intraepithelial lesion, and (3) factors that were associated with HPV regression.

STUDY DESIGN: The study was a cohort analytic design. An inception cohort of 618 women positive for HPV participated. ...

Known for Young Women |  Risk Hpv |  Human Papillomavirus Infection |  Dna Testing |  Cervical Intraepithelial
KOL Index score: 14054

OBJECTIVE: Anal cancer incidence is high in HIV-infected MSM. Screening for anal intraepithelial lesions and cancers is performed at specialized clinics and relies on high-resolution anoscopy (HRA) and anal cytology. Both approaches have limited reproducibility and sensitivity for detecting anal cancer precursors. We evaluated biomarkers for human papillomavirus (HPV)-related disease in a population of HIV-infected MSM.

METHODS: A cross-sectional screening study with passive follow-up ...

Known for Human Papillomavirus |  Anal Cancer |  Infected Msm |  Messenger Rna |  Sensitivity Specificity
KOL Index score: 13755

Anal squamous intraepithelial lesions (ASIL) are common in homosexual and bisexual men, and high-grade ASIL (HSIL) in particular may represent an anal cancer precursor. Cervical cytology is a useful screening tool for detection of cervical HSIL to prevent cervical cancer. To assess anal cytology as a screening tool for anal disease, we compared anal cytology with anoscopy and histopathology of anal biopsies. A total of 2958 anal examinations were performed on 407 HIV-positive and 251 ...

Known for Anal Cytology |  Screening Tool |  Sensitivity Specificity |  Squamous Intraepithelial |  Situ Carcinoma
KOL Index score: 13547

OBJECTIVE: The incidence of anal cancer among homosexual men exceeds that of cervical cancer in women, and HIV-positive homosexual men may be at even higher risk than HIV-negative men. Cervical cancer is preceded by high-grade squamous intra-epithelial lesions (HSIL) and anal HSIL may similarly be the precursor to anal cancer. In this study, we describe the incidence of and risk factors for HSIL in HIV-positive and HIV-negative homosexual and bisexual men.

DESIGN: Prospective cohort ...

Known for Negative Homosexual |  San Francisco |  Hiv Positive |  Incidence Anal Cancer |  Grade Squamous
KOL Index score: 13205

Anal human papillomavirus (HPV) infections are common, and the incidence of anal cancer is high in HIV-infected men who have sex with men (MSM). To evaluate the performance of HPV assays in anal samples, we compared the cobas HPV test (cobas) to the Roche Linear Array HPV genotyping assay (LA) and cytology in HIV-infected MSM. Cytology and cobas and LA HPV testing were conducted for 342 subjects. We calculated agreement between the HPV assays and the clinical performance of HPV testing ...

Known for Cobas Hpv |  Anal Cytology |  Clinical Performance |  Sensitivity Specificity |  Genotyping Techniques
KOL Index score: 13086

BACKGROUND: The impact of highly active antiretroviral therapy (HAART) on the natural history of HPV infection and anal squamous intraepithelial lesions (SIL) in HIV-infected men who have sex with men (MSM) is poorly documented. GOAL The goal of this study was to evaluate the prevalence of anal HPV infection and SIL inpatients under HAART.

STUDY DESIGN: Forty-five HIV-infected protease inhibitor-experienced MSM were enrolled in a cross-sectional study. Each patient provided anal samples ...

Known for Anal Squamous |  Antiretroviral Therapy |  Highly Active |  Hpv Infection |  Intraepithelial Lesions


Teresa Marie Darragh: Influence Statistics

Sample of concepts for which Teresa Marie Darragh is among the top experts in the world.
Concept World rank
participant performance cytotechnologists #1
hgain cases #1
hsil nonhsil categories #1
anorectal cytology arc #1
negative subcategories hsil #1
hsil 2 #1
p16 recommended #1
feasibility clinical detection #1
performance preparation type #1
malignancy 12 #1
terminology project #1
lsil baseline #1
treated hemicircumference #1
negative reference diagnosis #1
anal neoplasia specificity #1
trichomonas gynecologic cytology #1
participant college #1
regressed 6 #1
recurrence treatment zone #1
cervix terminology topic #1
preproficiency test #1
hsil adolescents #1
trial 29 #1
dysplastic lsil hsil #1
performance anal #1
hsil hybrid #1
hpv neoplastic cervix #1
23 hsils #1
hsil cervical neoplasms #1
introduction proficiency testing #1
40 anal lesions #1
revised terminology #1
negative slides hsil #1
vaginalis college #1
dysplastic hsil #1
modification laboratory practices #1
cytotechnologist laboratory #1
cases hgain #1
hsil conclusions #1
comparison program college #1
31 biopsy specimens #1
standard surveillance practices #1
falsepositive responses cancer #1
biopsy pathologists #1
incidence hsil #1
hhsils #1
time preparation types #1
classifying anal #1
hsil hybrid algorithm #1
positive p16 immunostain #1

Key People For Anal Cytology

Top KOLs in the world
Joel Michael Palefsky†
human papillomavirus anal cancer hpv infection
Teresa Marie Darragh
anal cytology human papillomavirus hpv infection
Naomi Jay†
anal cancer human papillomavirus intraepithelial lesions
Elizabeth A Holly†
pancreatic cancer san francisco pooled analysis
John Michael Berry†
anal cancer human papillomavirus resolution anoscopy
Charissa J Hogeboom
anal cytology screening tool washington state

Teresa Marie Darragh:Expert Impact

Concepts for whichTeresa Marie Darraghhas direct influence:Anal cytology,  Human papillomavirus,  Anal cancer,  Anal precancer,  Human immunodeficiency virus,  Hpv infection,  Anal intraepithelial neoplasia,  Squamous intraepithelial.

Teresa Marie Darragh:KOL impact

Concepts related to the work of other authors for whichfor which Teresa Marie Darragh has influence:Human papillomavirus,  Cervical cancer,  Hpv infection,  Intraepithelial neoplasia,  Anal cytology,  United states,  Young women.



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