Prominent publications by Sofie F M Bhatti

KOL Index score: 13636

The aim of this study is to investigate the effects of ghrelin and GH-releasing peptide-6 (GHRP-6) on the release of growth hormone (GH), adrenocorticotrophic hormone (ACTH), and cortisol in dogs with pituitary-dependent hyperadrenocorticism (PDH) and in healthy dogs of comparable age. In eight healthy dogs, the responses to ghrelin and GHRP-6 were compared to those of GH-releasing hormone (GHRH) and NaCl 0.9% (control). In seven dogs with PDH, the effects of ghrelin and GHRP-6 were ...

Known for Healthy Dogs |  Growth Hormone |  Ghrh Ghrp6 |  Gh Release |  Cortisol Concentrations
KOL Index score: 8405

The aim of this study was to investigate the effects of treatment with medroxyprogesterone acetate (MPA) on canine adenohypophyseal function. Five Beagle bitches were treated with MPA (10mg/kg, every 4 weeks) and their adenohypophyseal function was assessed in a combined adenohypophyseal function test. Four hypophysiotropic hormones (CRH, GHRH, GnRH, and TRH) were administered before and 2, 5, 8, and 11 months after the start of MPA treatment, and blood samples for determination of the ...

Known for Medroxyprogesterone Acetate |  Mpa Treatment |  Growth Hormone |  Basal Plasma |  Lh Fsh
KOL Index score: 8361

This article outlines the consensus proposal on diagnosis of epilepsy in dogs by the International Veterinary Epilepsy Task Force. The aim of this consensus proposal is to improve consistency in the diagnosis of epilepsy in the clinical and research settings. The diagnostic approach to the patient presenting with a history of suspected epileptic seizures incorporates two fundamental steps: to establish if the events the animal is demonstrating truly represent epileptic seizures and if ...

Known for Veterinary Epilepsy |  Epileptic Seizures |  Diagnostic Approach |  Task Force |  Seizure Disorders
KOL Index score: 7486

The clinical and clinicopathological characteristics, treatment and outcome of vermicular muscle contractions (myokymia) and generalized muscle stiffness (neuromyotonia) in 37 Jack Russell terriers were evaluated retrospectively. Thirty dogs were affected by both disorders, whereas seven were presented with myokymia and never developed neuromyotonia. Clinical signs started at the mean age of 8 months. Except for signs of myokymia and neuromyotonia, clinical and neurological examination ...

Known for Jack Russell |  Myokymia Neuromyotonia |  Clinical Signs |  Hereditary Ataxia |  Diseases Dogs
KOL Index score: 7438

The amplitude and frequency of growth hormone (GH) secretory pulses are influenced by a variety of hormonal signals, among which glucocorticoids play an important role. The aim of this study was to investigate the pulsatile secretion pattern of GH in dogs in which the endogenous secretion of glucocorticoids is persistently elevated, i.e. in dogs with pituitary-dependent hyperadrenocorticism (PDH). Blood samples for the determination of the pulsatile secretion pattern of GH were collected ...

Known for Growth Hormone |  Dogs Pdh |  Pulsatile Fashion |  Pituitary Gland |  Secreted Pulses
KOL Index score: 6999

BACKGROUND: Intranasal administration of benzodiazepines has shown superiority over rectal administration for terminating emergency epileptic seizures in human trials. No such clinical trials have been performed in dogs.

OBJECTIVE: To evaluate the clinical efficacy of intranasal midazolam (IN-MDZ), via a mucosal atomization device, as a first-line management option for canine status epilepticus and compare it to rectal administration of diazepam (R-DZP) for controlling status epilepticus ...

Known for Status Epilepticus |  Intranasal Administration |  Cessation Time |  Randomized Parallel |  5 Minutes
KOL Index score: 6864

We evaluated the feasibility of interictal single photon emission computed tomography (SPECT) to detect alterations in regional cerebral blood flow and neuronal activity in dogs with idiopathic epilepsy. Twelve dogs with idiopathic epilepsy underwent interictal technetium-99m-ethyl cysteinate dimer SPECT of the brain. Different cortical regions of interest (ROIs), 1 ROI at the cerebellum and 1 ROI at the subcortical area were evaluated by semiquantitative analysis and compared with a ...

Known for Epileptic Dogs |  Brain Perfusion |  Idiopathic Epilepsy |  Cysteinate Dimer |  Semiquantitative Analysis
KOL Index score: 6514

Dogs with epilepsy are among the commonest neurological patients in veterinary practice and therefore have historically attracted much attention with regard to definitions, clinical approach and management. A number of classification proposals for canine epilepsy have been published during the years reflecting always in parts the current proposals coming from the human epilepsy organisation the International League Against Epilepsy (ILAE). It has however not been possible to gain agreed ...

Known for Veterinary Epilepsy |  Companion Animals |  Task Force |  Current Understanding |  Terminology Classification
KOL Index score: 6140

The effects of three growth hormone secretagogues (GHSs), ghrelin, growth hormone-releasing peptide-6 (GHRP-6), and growth hormone-releasing hormone (GHRH), on the release of adenohypophyseal hormones, growth hormone (GH), adrenocorticotropic hormone (ACTH), thyroid-stimulating hormone (TSH), luteinising hormone (LH), prolactin (PRL) and on cortisol were investigated in young and old healthy Beagle dogs. Ghrelin proved to be the most potent GHS in young dogs, whereas in old dogs GHRH ...

Known for Growth Hormone |  Gh Release |  Lh Prl |  Anterior Prolactin |  Animals Cross
KOL Index score: 6097

OBJECTIVE: To evaluate retrospectively the efficacy of the suboccipital craniectomy and dorsal laminectomy of C1 with durotomy and placement of a dural graft for treatment of syringohydromyelia (SHM) because of cerebellar tonsil herniation in Cavalier King Charles spaniels (CKCS). This technique is used with great success in human medicine.

STUDY DESIGN: Four CKCS diagnosed by Magnetic resonance imaging (MRI) of SHM because of cerebellar tonsil herniation and not responsive to medical ...

Known for Charles Spaniels |  Dorsal Laminectomy |  Cavalier King |  2 Dogs |  Resonance Imaging
KOL Index score: 6079

Imepitoin has recently been approved in Europe for the management of dogs with idiopathic epilepsy. Currently, there is no evidence-based information available on the efficacy of antiepileptic drugs used as additions to the therapeutic regimen in dogs with idiopathic epilepsy that are not well controlled with imepitoin. The goal of this study was to evaluate the efficacy of phenobarbital or potassium bromide (KBr) as add-on antiepileptic drugs for controlling dogs refractory to a maximum ...

Known for Idiopathic Epilepsy |  Potassium Bromide |  Maximum Dose |  Antiepileptic Drugs |  Phenobarbital Kbr
KOL Index score: 5905

Brachial plexus trauma is a common clinical entity in small animal practice and prognostic indicators are essential early in the course of the disease. Magnetic stimulation of the radial nerve and consequent recording of the magnetic motor evoked potential (MMEP) was examined in 36 dogs and 17 cats with unilateral brachial plexus trauma. Absence of deep pain perception (DPP), ipsilateral loss of panniculus reflex, partial Horner's syndrome and a poor response to MMEP were related to the ...

Known for Magnetic Stimulation |  Brachial Plexus |  Radial Nerve |  Dogs Cats |  Panniculus Reflex
KOL Index score: 5309

In Europe, the number of antiepileptic drugs (AEDs) licensed for dogs has grown considerably over the last years. Nevertheless, the same questions remain, which include, 1) when to start treatment, 2) which drug is best used initially, 3) which adjunctive AED can be advised if treatment with the initial drug is unsatisfactory, and 4) when treatment changes should be considered. In this consensus proposal, an overview is given on the aim of AED treatment, when to start long-term treatment ...

Known for Canine Epilepsy |  Consensus Proposal |  Task Force |  Antiepileptic Drugs |  International Veterinary
KOL Index score: 5243

OBJECTIVE: To investigate the physiologic endocrine effects of food intake and food withholding via measurement of the circulating concentrations of acylated ghrelin, growth hormone (GH), insulin-like growth factor-I (IGF-I), glucose, and insulin when food was administered at the usual time, after 1 day's withholding, after 3 days' withholding and after refeeding the next day in healthy Beagles.

ANIMALS: 9 healthy Beagles.

PROCEDURES: Blood samples were collected from 8:30 AM to 5 PM ...

Known for Food Intake |  Ghrelin Concentrations |  Growth Hormone |  Glucose Insulin |  Blood Samples


Sofie F M Bhatti: Influence Statistics

Sample of concepts for which Sofie F M Bhatti is among the top experts in the world.
Concept World rank
imepitoin imepitoin withdrawal #3
imepitoin withdrawal #3

Key People For Healthy Dogs

Top KOLs in the world
Jörg Manfred Steiner
healthy dogs miniature schnauzers gastrointestinal disease
Jan S Suchodolski
healthy dogs fecal microbiota miniature schnauzers
Jens U Häggström
mitral valve congestive heart failure charles spaniels
David Hugh Lloyd
malassezia pachydermatis staphylococcus intermedius canine skin
Albert E Jergens
healthy dogs inflammatory bowel disease colonic mucosa
Jeffrey Scott Weese
clostridium difficile staphylococcus aureus fecal microbiota

Sofie F M Bhatti:Expert Impact

Concepts for whichSofie F M Bhattihas direct influence:Healthy dogs,  Growth hormone,  Idiopathic epilepsy,  Magnetic stimulation,  Status epilepticus,  Jack russell,  Veterinary epilepsy,  Jack russell terriers.

Sofie F M Bhatti:KOL impact

Concepts related to the work of other authors for whichfor which Sofie F M Bhatti has influence:Idiopathic epilepsy,  Clinical signs,  Growth hormone,  Diseases dogs,  Status epilepticus,  Laryngeal paralysis,  Epileptic seizures.



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Small Animal Department, Faculty of Veterinary Medicine, Ghent University, 9820 Merelbeke, Belgium | Small Animal Department, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium | Small Animal Department, Faculty of Veterinary Medici

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