 | Thierry Saint‐Marc |
Prominent publications by Thierry Saint‐Marc
A syndrome of peripheral fat wasting (lipodystrophy) in patients receiving long-term nucleoside analogue therapy
[ PUBLICATION ]
OBJECTIVE: To compare body composition, body fat distribution and insulin secretion in patients taking nucleoside reverse transcriptase inhibitor (NRTI) therapy.
DESIGN AND SETTING: Cross-sectional study in three French AIDS clinical centres.
PATIENTS: Forty-three HIV-infected patients on long-term NRTI therapy including stavudine (n = 27) or zidovudine (n = 16) and 15 therapy-naive HIV-infected patients (control group).
MAIN OUTCOME MEASURES: Fat wasting was assessed by physical ...
| Also Ranks for: Fat Wasting | stavudine zidovudine | lipodystrophy patients | body composition | tissue adult |
BACKGROUND: Fat distribution abnormalities have been reported in patients treated with various antiretroviral drug regimens. The LIPOCO study is an ongoing observational study of unselected HIV-infected patients which aims to better characterize such disorders and their metabolic correlations.
METHODS: Cross-sectional analysis of data collected at baseline in the first 154 male patients included. Investigators divided patients into four predetermined clinical categories of fat ...
| Also Ranks for: Fat Distribution | computed tomography | antiretroviral therapy | insulin levels | patients lipoatrophy |
The purpose of this article was to study the efficacy and tolerance of liposomal daunorubicin (DaunoXome) in the treatment of AIDS-associated Kaposi sarcoma (KS) as prescribed in France between September 1996 and September 1997. All patients with a positive HIV serology, histologically proven KS, and having received at least one daunorubicin treatment cycle during the study period were eligible for entry. Ninety-four patient files from 13 university hospital departments were ...
| Also Ranks for: Liposomal Daunorubicin | patients haart | kaposi sarcoma | treatment aids | highly active |
The place of fetal liver transplantation in the treatment of inborn errors of metabolism
[ PUBLICATION ]
Over the last 16 years, 202 fetal tissue transplants have been performed in our department to treat 29 patients with severe inborn errors of metabolism without immunodeficiency, 26 patients with congenital and severe immunodeficiency diseases, and 2 patients with severe aplastic anaemia. The actuarial survival curve of patients with inborn errors of metabolism treated with fetal liver transplantation shows a 12-year survival of 77%. The condition of many of these patients has been ...
| Also Ranks for: Inborn Errors | liver transplantation | fetal tissue | severe immunodeficiency diseases | preschool female |
Effects of metformin on insulin resistance and central adiposity in patients receiving effective protease inhibitor therapy
[ PUBLICATION ]
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| Also Ranks for: Insulin Resistance | central adiposity | hypoglycemic agents | protease inhibitor | effects metformin |
The effects of discontinuing stavudine therapy on clinical and metabolic abnormalities in patients suffering from lipodystrophy
[ PUBLICATION ]
&NA
| Also Ranks for: Discontinuing Stavudine | reverse transcriptase inhibitors | hiv infections | body composition | humans lipodystrophy |
| Also Ranks for: Intravenous Immunoglobulins | immunodeficiency syndrome |
| Also Ranks for: Buffalo Hump | hiv1 infection | body composition | adipose tissue | hiv agents |
| Also Ranks for: Aids Opportunistic |
Key People For Fat Wasting
Thierry Saint‐Marc:Expert Impact
Concepts for whichThierry Saint‐Marchas direct influence:Fat wasting, Fat distribution, Liposomal daunorubicin, Stavudine zidovudine, Rubra pilaris, Stavudine therapy, Intravenous immunoglobulins, Lipodystrophy patients.
Thierry Saint‐Marc:KOL impact
Concepts related to the work of other authors for whichfor which Thierry Saint‐Marc has influence:Antiretroviral therapy, Insulin resistance, Hiv infection, Protease inhibitors, Lipodystrophy syndrome, Adipose tissue, Body composition.
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