• Disease
  • Incontinentia
  • Incontinentia Pigmenti
  • Morton F Goldberg

    Prominent publications by Morton F Goldberg

    KOL Index score: 30123

    BACKGROUND: Traumatic hyphema is the entry of blood into the anterior chamber (the space between the cornea and iris) subsequent to a blow or a projectile striking the eye. Hyphema uncommonly causes permanent loss of vision. Associated trauma (e.g., corneal staining, traumatic cataract, angle recession glaucoma, optic atrophy, etc.) may seriously affect vision. Such complications may lead to permanent impairment of vision. Patients with sickle cell trait/disease may be particularly ...

    Also Ranks for: Traumatic Hyphema |  medical interventions |  aminocaproic acid |  secondary hemorrhage |  vision patients
    KOL Index score: 21726

    BACKGROUND: Traumatic hyphema is the entry of blood into the anterior chamber (the space between the cornea and iris) subsequent to a blow or a projectile striking the eye. Hyphema uncommonly causes permanent loss of vision. Associated trauma (e.g. corneal staining, traumatic cataract, angle recession glaucoma, optic atrophy, etc.) may seriously affect vision. Such complications may lead to permanent impairment of vision. Patients with sickle cell trait/disease may be particularly ...

    Also Ranks for: Traumatic Hyphema |  medical interventions |  secondary hemorrhage |  aminocaproic acid |  visual acuity
    KOL Index score: 12103

    PURPOSE: To evaluate safety and efficacy of the angiostatic agent anecortave acetate, compared with a placebo, for treatment of subfoveal choroidal neovascularization (CNV).

    DESIGN: Ongoing masked, randomized, placebo-controlled, parallel evaluation of anecortave acetate (30 mg, 15 mg, and 3 mg) versus a placebo.

    PARTICIPANTS: There were 128 eyes of 128 patients with subfoveal CNV secondary to age-related macular degeneration who were enrolled and treated, with 80% (102/128) of eyes ...

    Also Ranks for: Anecortave Acetate |  macular degeneration |  independent safety committee |  angiogenesis inhibitors |  1 year
    KOL Index score: 10154

    PURPOSE: To describe visual acuity and angiographic outcomes of juxtafoveal choroidal neovascularization (CNV) treated with photodynamic therapy and verteporfin (PDT).

    METHODS: Four hundred eighty-four consecutive eyes of 446 patients treated with PDT from January 1, 2001, to June 30, 2002, were identified from billing records. Fluorescein angiograms were reviewed retrospectively to identify juxtafoveal CNV. Eligible patients had CNV in which the central boundary of the lesion was ...

    Also Ranks for: Photodynamic Therapy |  choroidal neovascularization |  visual acuity |  12 months |  verteporfin pdt
    KOL Index score: 9875

    PURPOSE: To evaluate clinical safety and efficacy of the angiostatic agent anecortave acetate for treatment of subfoveal choroidal neovascularization secondary to AMD.

    METHODS: 128 patients were randomized to placebo treatment or one of three anecortave acetate doses. Study medication was administered as a posterior juxtascleral injection onto the posterior scleral surface. Best-corrected logMAR vision was obtained at baseline and follow-up visits. Fluorescein angiograms were evaluated ...

    Also Ranks for: Anecortave Acetate |  macular degeneration |  placebo treatment |  visual acuity |  patients amd
    KOL Index score: 8951

    Purpose: Retinal vascular occlusions in sickle cell anemia patients cause tissue ischemia and the release of angiogenic mediators that promote the development of retinal neovascularization, initiating proliferative sickle retinopathy (PSR). Laser photocoagulation (LPC) has emerged as the most common treatment for PSR. Nonetheless, only two randomized controlled clinical trials have evaluated the use of LPC for PSR, and both failed to definitively demonstrate efficacy of this approach. ...

    Also Ranks for: Proliferative Sickle Retinopathy |  vegf psr |  expression hif1α |  retinal neovascularization |  hypoxiainducible factor
    KOL Index score: 8904

    PURPOSE: To report ocular and renal findings specific to the inheritable entity called papillorenal (also known as renal-coloboma) syndrome and relate these to a common cause.

    DESIGN: Observational case series and genetic study.

    PARTICIPANTS: Two unrelated probands presenting with absent central retinal vessels and 11 available family members.

    TESTING: Doppler ultrasonographic imaging of the optic nerves and kidneys, fluorescein angiography, and genetic testing for PAX2 mutations were ...

    Also Ranks for: Papillorenal Syndrome |  pax2 mutations |  retinal diseases |  renal hypoplasia |  genetic testing
    KOL Index score: 8821

    Photocoagulation of the monkey fundus with an argon-krypton laser photocoagulator was performed. Lesions produced by argon and krypton wavelengths were compared at various power settings, spot sizes, and exposure durations. At low energy levels argon laser lesions appeared clinically stronger than those produced by the krypton mode. Lesions in the foveal area produced with the argon laser demonstrated more extensive microscopic damage to the inner retinal layers than did those produced ...

    Also Ranks for: Krypton Laser |  retinal vessels |  argon burns |  bruchs membrane |  fundus oculi
    KOL Index score: 8670

    To evaluate the usefulness of magnetic resonance imaging (MRI) in the evaluation of leukocoric eyes, the authors studied 28 patients with either leukocoria or intraocular mass with a 1.5-tesla (T) MRI imager. Retinoblastomas were reliably distinguished from Coats' disease, toxocariasis, and persistent hyperplastic primary vitreous on the basis of MRI findings. Calcification cannot be reliably detected on MRI scans. Lesions elevated less than 4 mm may not be detected reliably by MRI at ...

    Also Ranks for: Magnetic Resonance |  computed tomography |  retinoblastoma mri |  coats disease |  uveal melanoma
    KOL Index score: 8640

    In a patient with clinical features of both myoclonus epilepsy ragged-red fibers (MERRF) and Kearns-Sayre syndrome (KSS), we identified a novel guanine-to-adenine mitochondrial DNA (mtDNA) mutation at nucleotide 3255 (G3255A) of the tRNA(Leu(UUR)) gene. Approximately 5% of the skeletal muscle fibers had excessive mitochondria by succinate dehydrogenase histochemistry while a smaller proportion showed cytochrome c oxidase (COX) deficiency. In skeletal muscle, activities of mitochondrial ...

    Also Ranks for: Sayre Syndrome |  mitochondrial rna |  skeletal muscle |  sequence dna |  merrf kearns
    KOL Index score: 8468

    BACKGROUND: Mutations in BEST1 account for autosomal dominant vitreoretinochoroidopathy (ADVIRC), a rare inherited retinal dystrophy with presenile cataracts and incomplete anterior segment development. The long-term clinical findings and visual prognosis of these patients continues to evolve over time.

    MATERIALS AND METHODS: The retina was assessed by fundus photography, fluorescein angiography, and spectral domain optical coherence tomography. Sanger dideoxy chain-termination ...

    Also Ranks for: Autosomal Dominant |  best1 advirc |  missense mutation |  retinal diseases |  fluorescein angiography
    KOL Index score: 7963

    PURPOSE: Ocular ischemia from polyarteritis nodosa (PAN) is rare. The authors present a case of multifocal ocular infarction from PAN.

    METHODS AND RESULTS: A 70-year-old woman developed hand and foot numbness followed by intermittent blurred vision and binocular horizontal diplopia. Two weeks later, she suddenly lost vision in the right eye from a central retinal artery occlusion and then developed a left anterior ischemic optic neuropathy and bilateral triangular choroidal abnormalities ...

    Also Ranks for: Polyarteritis Nodosa |  optic neuropathy |  choroidal infarction |  artery occlusion |  central retinal
    KOL Index score: 7899

    The recent success of therapies directly targeting the angiogenic mediator, vascular endothelial growth factor (VEGF), for the treatment of proliferative diabetic retinopathy has encouraged clinicians to extend the use of anti-VEGF therapies for the treatment of another ischemic retinal vascular disease, proliferative sickle cell retinopathy (PSR), the most common cause of irreversible blindness in patients with sickle cell disease. However, results from case reports evaluating anti-VEGF ...

    Also Ranks for: Patients Psr |  sickle retinopathy |  retinal neovascularization |  angiogenic factor |  angiopoietin 4
    KOL Index score: 7844

    BACKGROUND: One of the largest series of patients with incontinentia pigmenti who have undergone detailed ophthalmologic examination is reported here, including previously unrecognized findings with visually disabling consequences.

    METHODS: Thirteen females with incontinentia pigmenti from eight unrelated families were evaluated. The diagnosis of incontinentia pigmenti had been established previously by a referring pediatrician or dermatologist in 12 patients and by the authors in one ...

    Also Ranks for: Incontinentia Pigmenti |  preschool diagnosis |  retinal manifestations |  foveal hypoplasia |  central nervous


    Morton F Goldberg: Influence Statistics

    Sample of concepts for which Morton F Goldberg is among the top experts in the world.
    Concept World rank
    exposed orbital implant #1
    anterior chambers #1
    16222 cases #1
    review medical interventions #1
    9 maculas #1
    choroidoretinal vascular #1
    20 control eyes #1
    ophthalmoscopy regression #1
    neovascularization tractional #1
    factor macular ischemia #1
    synechiae elevated #1
    po2 aqueous humor #1
    instrument vessels #1
    neovascular patches #1
    hyphema topical #1
    manifestations incontinentia #1
    patients retinal manifestations #1
    uvea fundus #1
    vessels fluorescein #1
    ora serrata aspects #1
    vision goldberg #1
    photocoagulated area #1
    hospitalassociated charges #1
    secondary glaucoma hyphema #1
    effective technique photocoagulation #1
    cycloplegics aspirin #1
    late recurrence patient #1
    subsequent palpebral fissure #1
    literature retinal vascular #1
    350 patients incidence #1
    hyphema primary diagnosis #1
    dexamethasone dramatic reduction #1
    analogy dermatoglyphics #1
    sequential macular angiography #1
    destruction retinal layers #1
    hypertrichosis bones child #1
    segmented dilations #1
    neural crest mexican #1
    anastomoses average interval #1
    clinical considerations articulation #1
    hirschsprung mahakrishnan #1
    disruption ibrb #1
    papillary burns #1
    tractional retinoschisis patients #1
    macula effective method #1
    iop rebleeding #1
    infarction incontinentia #1
    sickle haemoglobinopathies patients #1
    epipapillary fibroglial tissue #1
    stellate remnants #1

    Key People For Incontinentia Pigmenti

    Top KOLs in the world
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    incontinentia pigmenti ectodermal dysplasia congenital tufting enteropathy
    Morton F Goldberg
    incontinentia pigmenti traumatic hyphema sickle cell
    Munnich Munnich
    respiratory chain hirschsprung disease human pair

    Morton F Goldberg:Expert Impact

    Concepts for whichMorton F Goldberghas direct influence:Incontinentia pigmenti,  Traumatic hyphema,  Sickle cell,  Argon laser photocoagulation,  Fluorescein angiography,  Proliferative sickle retinopathy,  Visual acuity,  Argon laser.

    Morton F Goldberg:KOL impact

    Concepts related to the work of other authors for whichfor which Morton F Goldberg has influence:Sickle cell disease,  Diabetic retinopathy,  Incontinentia pigmenti,  Visual acuity,  Retinal detachment,  Fluorescein angiography,  Macular edema.



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    Johns Hopkins Medical Institutions, Baltimore, USA | Retina Division, Wilmer Eye Institute, The Johns Hopkins University School of Medicine and Hospital, Baltimore, Maryland | Department of Ophthalmology, Johns Hopkins Medical Institutions, Baltimore