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    • Ngolela Esther Babady
    • Ngolela Esther Babady: Influence Statistics

      Ngolela Esther Babady

      Ngolela Esther Babady

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      From the, Infectious Diseases Service | Clinical Microbiology Service, Department of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA | ...

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      Ngolela Esther Babady:Expert Impact

      Concepts for whichNgolela Esther Babadyhas direct influence:Influenza virus,Xpert mtb,Lymphoid malignancies,Clonal hematopoiesis,Clostridium difficile,New york city,Difficile infection,Clinical specimens.

      Ngolela Esther Babady:KOL impact

      Concepts related to the work of other authors for whichfor which Ngolela Esther Babady has influence:Clostridium difficile,Patients cancer,Respiratory viruses,Friedreich ataxia,Influenza virus,Transplant recipients,Fungal infections.

      KOL Resume for Ngolela Esther Babady

      Year
      2022

      From the, Infectious Diseases Service

      2021

      Infectious Diseases Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.

      Department of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA

      Memorial Sloan Kettering Cancer Center, U.S.A. Electronic address:

      Authors of equal contribution.

      2020

      Department Medicine, Memorial Sloan Kettering Cancer Center, New York, New York

      2019

      Memorial Sloan-Kettering Cancer Center, New York, NY.

      2018

      Memorial Sloan Kettering Cancer Center, New York, New York, USA

      2017

      Infectious Disease Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, United States

      Department of Laboratory Medicine, Memorial Sloan Kettering Cancer Center.

      2016

      Clinical Microbiology Service, Department of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA

      2015

      Microbiology Service, Department of Laboratory Medicine at Memorial Sloan Kettering Cancer Center, New York, NY, USA

      2014

      Clinical Microbiology Service, Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

      2013

      Clinical Microbiology Service, Memorial Sloan-Kettering Cancer Center, New York, New York, USA

      Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, S428D, New York, NY, 10044,

      2012

      Clinical Microbiology Service, Department of Laboratory Medicine,

      Memorial Sloan-Kettering Cancer Center, New York, New York, USA

      2011

      Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905

      Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York

      2010

      Clinical Microbiology Service, Department of Clinical Laboratories

      2009

      Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA.

      2008

      Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA

      2007

      Department of Pediatric and Adolescent Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA

      Biochemistry and Molecular Biology and

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      Sample of concepts for which Ngolela Esther Babady is among the top experts in the world.
      Concept World rank
      gpp targets #1
      specificity lrt #1
      559 994 #1
      evaluation luminex #1
      nps roche #1
      roche cobas nps #1
      adenovirus 46 #1
      npa gm lfa #1
      detected bfgp #1
      bw bacterial culture #1
      cancer patient population #1
      opportunities clinical microbiologist #1
      pneumophila aspergillus #1
      pooled nps samples #1
      2009 h1 virus #1
      healthcare settings prevention #1
      309 decrease #1
      19 noncompliant #1
      448 serum samples #1
      pooling 6 samples #1
      methodologies increased sensitivity #1
      metagenomics plasma #1
      955 984 #1
      6pool approach nps #1
      alerts noncompliant #1
      current methodologies clinicians #1
      498 309 #1
      gm eia testing #1
      data ridts #1
      564 samples #1
      fourteen 24 samples #1
      46 new version #1
      evaluated eplex #1
      singleplex legionella #1
      cancer inpatient cohort #1
      aspergillosis 100 #1
      bfgp detected #1
      954995 #1
      clinical tests impact #1
      diagnostic ridt #1
      cancer patients minireview #1
      ordering ovum #1
      ridts clia #1
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      Prominent publications by Ngolela Esther Babady

      KOL-Index: 12762

      Rapid and accurate diagnosis of influenza is important for infection control, as well as for patient management. Alere i Influenza A&B is an isothermal nucleic acid amplification-based integrated system for detection and differentiation of influenza virus A and influenza virus B. The performance of the Alere i Influenza A&B was screened using frozen nasopharyngeal-swab specimens collected in viral transport medium (VTM) that were originally tested fresh with the FilmArray Respiratory ...

      Known for Influenza Virus | Rapid Detection | Alere Assay | Patient Management | Infection Control
      KOL-Index: 12506

      BACKGROUND: Serum (1,3)-beta-D glucan (BDG) is increasingly used to guide the management of suspected Pneumocystis pneumonia (PCP). BDG lacks specificity for PCP, and its clinical performance in high-risk cancer patients has not been fully assessed. Polymerase chain reaction (PCR) for PCP detection is highly sensitive, but cannot differentiate between colonization and infection. We evaluated the diagnostic performance of serum BDG in conjunction with PCP PCR on respiratory samples in ...

      Known for Clinical Performance | Pcp Patients | Sensitivity Specificity | Polymerase Chain Reaction | Carinii Pneumonia
      KOL-Index: 12342

      Respiratory viruses are increasingly recognized as serious causes of morbidity and mortality in immunocompromised patients. The rapid and sensitive detection of respiratory viruses is essential for the early diagnosis and administration of appropriate antiviral therapy, as well as for the effective implementation of infection control measures. We compared the performance of two commercial assays, xTAG RVP Fast (Luminex Diagnostics, Toronto, Canada) and FilmArray RVP (FA RVP; Idaho ...

      Known for Respiratory Viruses | Rvp Fast | Pediatric Patients | Luminex Xtag | Infections Sensitivity
      KOL-Index: 11931

      This multicenter study was designed to assess the accuracy and reproducibility of the Vitek MS v3.0 matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry system for identification of Mycobacterium and Nocardia species compared to DNA sequencing. A total of 963 clinical isolates representing 51 taxa were evaluated. In all, 663 isolates were correctly identified to the species level (69%), with another 231 (24%) correctly identified to the complex or ...

      Known for Mass Spectrometry | Assisted Laser | Nocardia Species | Complex Level | Diagnostic Reproducibility
      KOL-Index: 11704

      Clostridium difficile is the most common cause of health care-associated diarrhea. Accurate and rapid diagnosis is essential to improve patient outcome and prevent disease spread. We compared our two-step diagnostic algorithm, an enzyme immunoassay for glutamate dehydrogenase (GDH) followed by the cytotoxin neutralization test (CYT) with a turnaround time of 24 to 48 h, versus the Cepheid Xpert C. difficile Epi assay, a PCR-based assay with a turnaround time of <1 h. In the first phase ...

      Known for Xpert Clostridium | Difficile Infection | Epi Assay | Nap1 Strain | Turnaround Time
      KOL-Index: 11039

      Blastomyces dermatitidis and Histoplasma capsulatum are dimorphic fungi that often cause self-limited respiratory infections. However, they may also cause severe disseminated disease, depending on the level of the exposure to the organism and the host immune status. In addition, patients with infections caused by these fungi may have very similar clinical presentations. Although microbiologic culture is a standard method for detecting these pathogens, their recovery may require days to ...

      Known for Clinical Specimens | Histoplasma Capsulatum | Blastomyces Dermatitidis | Time Pcr | Culture Isolates
      KOL-Index: 11014

      OBJECTIVES: Clostridium difficile infection (CDI) is a toxin-mediated disease. Oncology patients are at increased risk for developing CDI. Diagnosis of CDI by PCR has led to misclassification of some C. difficile carriers as CDI cases. We determined if an optimized C. difficile PCR cycle threshold value (CT) could reliably predict presence of free toxin, and in turn improve the utility of PCR in detecting clinically relevant CDI in oncology patients.

      METHODS: 183 consecutive patients ...

      Known for Difficile Infection | Cdi Pcr | Free Toxin | Threshold Cycle | Predict Presence
      KOL-Index: 10344

      Cytomegalovirus (CMV) viral loads in hematopoietic stem cell transplant (HSCT) recipients are typically monitored using quantitative molecular assays. The Roche Cobas AmpliPrep/Cobas TaqMan CMV test (Cobas CMV) has recently been cleared by the FDA for the monitoring of CMV viral loads in plasma samples from transplant patients. In this study, we compare and correlate the viral loads obtained by a laboratory-developed test (LC CMV) (using Roche analyte-specific reagents [ASR] on the ...

      Known for Viral Loads | Stem Cell | Plasma Blood | Transplant Recipients | Cmv Assay
      KOL-Index: 9316

      BACKGROUND: The sensitivity of the MVista Histoplasma antigen enzyme immunoassay (MiraVista Diagnostics) has been evaluated in disseminated histoplasmosis in patients with AIDS and in the "epidemic" form of acute pneumonia. Moreover, there has been no evaluation of the sensitivity of antigenemia detection in disseminated histoplasmosis after the implementation of methods to dissociate immune complexes and denature released antibodies. The goal of this study was to determine the ...

      Known for Disseminated Histoplasmosis | Fungal Antigens | Immunocompromised Patients | Sensitivity Antigen Detection | Lung Diseases
      KOL-Index: 9286

      The performance of the new ePlex Respiratory Pathogen (RP) panel (GenMark Diagnostics) for the simultaneous detection of 19 viruses (influenza A virus; influenza A H1 virus; influenza A 2009 H1 virus; influenza A H3 virus; influenza B virus; adenovirus; coronaviruses [HKU1, OC43, NL63, and 229E]; human rhinovirus/enterovirus; human metapneumovirus; parainfluenza viruses 1, 2, 3, and 4; and respiratory syncytial virus [RSV] [RSV subtype A and RSV subtype B]) and 2 bacteria (Mycoplasma ...

      Known for Eplex Respiratory | Multicenter Evaluation | Influenza Virus | Pathogen Panel | Nasopharyngeal Swabs
      KOL-Index: 8402

      Invasive fungal infections are an important cause of morbidity and mortality affecting primarily immunocompromised patients. While fungal identification to the species level is critical to providing appropriate therapy, it can be slow and laborious and often relies on subjective morphological criteria. The use of matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry has the potential to speed up and improve the accuracy of identification. In this ...

      Known for Filamentous Fungi | Multicenter Evaluation | Vitek V30 | Species Level | Fungal Identification
      KOL-Index: 7888

      The aim of this study was to compare the clinical and laboratory characteristics of Clostridium difficile infection (CDI) in patients with discordant test results for the cytotoxin assay (CYT) and PCR assays. A retrospective study from May to August 2008 and March to May 2010 was performed. CDI was diagnosed in 128 patients. PCR increased the yield of C. difficile cases by 2-fold compared to that of the CYT assay. Fifty-six cases (44%) were detected by PCR only (CYT negative). Forty-nine ...

      Known for Clostridium Difficile | Cdi Patients | Cyt Pcr | Diagnostic Test | Preschool Clostridioides
      KOL-Index: 6867

      Patients with cancer have high mortality from coronavirus disease 2019 (COVID-19), and the immune parameters that dictate clinical outcomes remain unknown. In a cohort of 100 patients with cancer who were hospitalized for COVID-19, patients with hematologic cancer had higher mortality relative to patients with solid cancer. In two additional cohorts, flow cytometric and serologic analyses demonstrated that patients with solid cancer and patients without cancer had a similar immune ...

      Known for Patients Cancer | Cd8 Cells | Cellular Immunity | Acute Covid19 | Humoral Responses
      KOL-Index: 6425

      PURPOSE: A circulating tumor DNA (ctDNA) test to detect plasma Epstein-Barr viral DNA can be used to screen for early nasopharyngeal cancers; however, the reported sensitivity of viral ctDNA tests to detect human papillomavirus (HPV)-associated cancers is modest. We assessed the utility of droplet digital polymerase chain reaction (ddPCR) to detect early-stage HPV-associated cancers using sequential HPV16 and HPV33 assays that account for HPV subtype distribution and subtype sequence ...

      Known for Liquid Biopsy | Human Papillomavirus | Hpv Ctdna | Squamous Cell | Tumor Dna
      KOL-Index: 6420

      As of 10 April 2020, New York State had 180,458 cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and 9,385 reported deaths. Patients with cancer comprised 8.4% of deceased individuals1. Population-based studies from China and Italy suggested a higher coronavirus disease 2019 (COVID-19) death rate in patients with cancer2,3, although there is a knowledge gap as to which aspects of cancer and its treatment confer risk of severe COVID-194. This information is critical ...

      Known for Patients Cancer | Hospitalization Severe Disease | Severe Outcomes | Mechanical Ventilation | Symptomatic Covid19

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      From the, Infectious Diseases Service | Clinical Microbiology Service, Department of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA | Infectious Diseases Service, Department of Medicine, Memorial Sloan Kettering Cancer

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