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    • Intestinal Permeability
    • Anthony Otley
    • Anthony Otley: Influence Statistics

      Anthony Otley

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      Anthony Otley:Expert Impact

      Concepts for whichAnthony Otleyhas direct influence:Intestinal permeability,Crohns disease,Gut inflammation,Microbial composition,Dietary patterns,Increased intestinal,Fecal calprotectin,Gut microbiome.

      Anthony Otley:KOL impact

      Concepts related to the work of other authors for whichfor which Anthony Otley has influence:Intestinal permeability,Inflammatory bowel disease,Gut microbiome,Healthy cotwins,Dietary patterns,Unrelated patients,Multiple sclerosis prodrome.

      KOL Resume for Anthony Otley

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      Sample of concepts for which Anthony Otley is among the top experts in the world.
      Concept World rank
      longterm dietary clusters #56
      2289 healthy fdrs #56
      clusters dc3 #56
      dc3 diet #56
      compositions subclinical #56
      gut inflammation cohort #56
      dc3 mediterranean diet #56
      abnormal lmr diagnosis #64
      lmr abnormal #64
      items fecal #65
      abnormal lmr #66
      defined fecal #76
      baseline lmr #87
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      Prominent publications by Anthony Otley

      KOL-Index: 4612

      Excessive intestinal permeability or intestinal barrier dysfunction as measured by various assays has been observed in various diseases. However, little is known about the factors contributing to altered gut permeability in these diseases. Our objective was to determine the genetic determinants of altered gut permeability as measured by the lactulose mannitol fractional excretion ratio (LacMan ratio) in 1075 healthy first-degree relatives of patients with Crohn's disease (CD). In a ...

      Known for Intestinal Permeability | Degree Relatives | Crohns Disease | Lactulose Mannitol | Altered Gut
      KOL-Index: 4507

      BACKGROUND & AIMS: Increased intestinal permeability has been associated with Crohn's disease (CD), but it is not clear whether it is a cause or result of the disease. We performed a prospective study to determine whether increased intestinal permeability is associated with future development of CD.

      METHODS: We assessed the intestinal permeability, measured by the urinary fractional excretion of lactulose-to-mannitol ratio (LMR) at recruitment in 1420 asymptomatic first-degree relatives ...

      Known for Intestinal Permeability | Crohn Disease | Future Development | Lactulose Mannitol | Barrier Function
      KOL-Index: 207

      BACKGROUND & AIMS: Case-control studies have shown that patients with Crohn's disease (CD) have a microbial composition different from healthy individuals. Although the causes of CD are unknown, epidemiologic studies suggest that diet is an important contributor to CD risk, potentially via modulation of bacterial composition and gut inflammation. We hypothesized that long-term dietary clusters (DCs) are associated with gut microbiome compositions and gut inflammation. Our objectives were ...

      Known for Fecal Calprotectin | Crohn Disease

      Key People For Intestinal Permeability

      Top KOLs in the world
      #1
      Ingvar T Bjarnason
      intestinal permeability ulcerative colitis coeliac disease
      #2
      Ian S Menzies
      intestinal permeability coeliac disease cirrhotic patients
      #3
      Jerrold R Turner
      tight junction barrier function epithelial cells
      #4
      Jon B Meddings
      intestinal permeability crohns disease nutrient absorption
      #5
      ANdrew J Macpherson
      intestinal permeability blood loss cardiopulmonary bypass
      #6
      Alessio Fasano
      celiac disease intestinal permeability zonula occludens toxin
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