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    • Kenneth K K Wang
    • Kenneth K K Wang

      Kenneth K K Wang

      Department of Gastroenterology, Mayo Clinic, Rochester, Minnesota. | Barrett's Esophagus Unit, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota. ...



      KOL Resume for Kenneth K K Wang


      Department of Gastroenterology, Mayo Clinic, Rochester, Minnesota.


      Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.


      Mayo Clinic, Rochester, Minnesota, USA.


      Master of Science in Biotechnology Graduate Program, Northwestern University, Evanston, Illinois.


      Division of Gastroenterology and Hepatology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.


      Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA


      Mayo Clinic, Department of Gastroenterology, Rochester, Minnesota, USA


      The Practice Parameters Committee of the American College of Gastroenterology


      Department of Medicine, Mayo School of Medicine, Rochester, Minnesota, Canada



      Kenneth K K Wang: Influence Statistics

      Sample of concepts for which Kenneth K K Wang is among the top experts in the world.
      Concept World rank
      pooled irs recurrent #1
      follow achieving #1
      longterm followup crim #1
      followup pooled irs #1
      recurrences dysplastic #1
      dysplastic hgd eac #1
      recurrence barrett esophagus #1
      recurrent dysplastic #1
      crim endoscopic therapy #1
      follow crim #1
      crim endoscopic #1
      recurrence crim #1
      eac year #2
      dysplastic hgd #3
      age 3 models #5
      50 progressors #5
      rigorous overfitting correction #5
      4 years tier #5
      145 nonprogressors #5
      tier 4 years #5
      2 years tier #5
      ablation complete eradication #6
      ablation disease progression #6
      endomicroscopy tce #6
      ablation sham procedure #6
      oct tce #6
      rate complete eradication #6
      radiofrequency ablation rate #6
      therapy barretts esophagus #6
      sham procedure control #6
      achieving crim #6
      sham procedure ablation #6
      incremental aucs #7
      recurrence achieving #8
      200 patientyears #8
      radiofrequency ablation 95 #8
      studies longterm followup #8
      accurate recurrence risk #9
      endoscopic landmarks #9
      95 patientyear #9


      Prominent publications by Kenneth K K Wang

      KOL-Index: 12808

      BACKGROUND: Barrett's esophagus, a condition of intestinal metaplasia of the esophagus, is associated with an increased risk of esophageal adenocarcinoma. We assessed whether endoscopic radiofrequency ablation could eradicate dysplastic Barrett's esophagus and decrease the rate of neoplastic progression.

      METHODS: In a multicenter, sham-controlled trial, we randomly assigned 127 patients with dysplastic Barrett's esophagus in a 2:1 ratio to receive either radiofrequency ablation (ablation ...

      Known for Radiofrequency Ablation | Complete Eradication Dysplasia | Intestinal Metaplasia | Dysplastic Barretts Esophagus | Neoplastic Progression
      KOL-Index: 10759

      BACKGROUND AND AIMS: Previous estimates of incidence of intestinal metaplasia (IM) recurrence after achieving complete remission of IM (CRIM) through endoscopic therapy of Barrett's esophagus (BE) have varied widely. We performed a systematic review and meta-analysis of studies to estimate an accurate recurrence risk after CRIM.

      METHODS: We performed a systematic search of multiple literature databases through June 2015 to identify studies reporting long-term follow-up after achieving ...

      Known for Endoscopic Therapy | Recurrence Crim | Hgd Eac | Barrett Esophagus | Complete Remission
      KOL-Index: 7746

      PURPOSE: T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive disease, affecting children and adults. Chemotherapy treatments show high response rates but have debilitating effects and carry risk of relapse. Previous work implicated NOTCH1 and other oncogenes. However, direct inhibition of these pathways affects healthy tissues and cancer alike. Our goal in this work has been to identify enzymes active in T-ALL whose activity could be targeted for therapeutic ...

      Known for Cell Leukemia | Usp7 Tall | Ubiquitin Specific | Expression Regulation | Xenograft Model
      KOL-Index: 7011

      Esophageal adenocarcinoma risk in Barrett's esophagus (BE) is increased 30- to 125-fold versus the general population. Among all BE patients, however, neoplastic progression occurs only once per 200 patient-years. Molecular biomarkers are therefore needed to risk-stratify patients for more efficient surveillance endoscopy and to improve the early detection of progression. We therefore performed a retrospective, multicenter, double-blinded validation study of eight BE progression ...

      Known for Methylation Biomarkers | Neoplastic Progression | Early Detection | Barretts Esophagus | Roc Curve
      KOL-Index: 6583

      This article reviews progress in chemopreventive drug development, especially data and concepts that are new since the 2002 AACR report on treatment and prevention of intraepithelial neoplasia. Molecular biomarker expressions involved in mechanisms of carcinogenesis and genetic progression models of intraepithelial neoplasia are discussed and analyzed for how they can inform mechanism-based, molecularly targeted drug development as well as risk stratification, cohort selection, and ...

      Known for Intraepithelial Neoplasia | Drug Development | Risk Stratification | New Agents | Molecular Biomarkers
      KOL-Index: 3879

      BACKGROUND: Probe-based confocal laser endomicroscopy (pCLE) provides microscopic imaging during an endoscopic procedure. Its introduction as a standard modality in gastroenterology has brought significant progress in management strategies, affecting many aspects of clinical care and requiring standardisation of practice and training.

      OBJECTIVE: This study aimed to provide guidance on the standardisation of its practice and training in Barrett's oesophagus, biliary strictures, colorectal ...

      Known for Consensus Report | Confocal Laser | Diagnostic Performance | Endoscopic Procedure | Modified Delphi Approach
      KOL-Index: 3768

      BACKGROUND & AIMS: Tethered capsule endomicroscopy (TCE) involves swallowing a small tethered pill that implements optical coherence tomography (OCT) imaging, procuring high resolution images of the whole esophagus. Here, we demonstrate and evaluate the feasibility and safety of TCE and a portable OCT imaging system in patients with Barrett's esophagus (BE) in a multi-center (5-site) clinical study.

      METHODS: Untreated patients with BE as per endoscopic biopsy diagnosis were eligible to ...

      Known for Tethered Capsule | Oct Tce | Unsedated Patients | Barrett Esophagus | Optical Coherence Tomography
      KOL-Index: 1691
      Known for Updated Guidelines | Diagnosis Surveillance | Esophagus Barrett
      KOL-Index: 210

      Improvements in narrow band imaging (NBI) may provide an improved view of colonic mucosa for detection of polyps and adenomas. In this issue, Leung et al. report findings to suggest that this next-generation NBI technology is superior to conventional high-definition white light endoscopy in polyp detection. These findings are based on brighter illumination, which has been a problem with older generations of NBI, which did not increase polyp detection but were useful for polyp ...

      Known for Narrow Band

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      Kenneth K K Wang:Expert Impact

      Concepts for whichKenneth K K Wanghas direct influence:Intraepithelial neoplasia,  Endoscopic therapy,  Radiofrequency ablation,  Tethered capsule,  Patients ablation,  Methylation biomarkers,  Barretts esophagus,  Recurrence crim.

      Kenneth K K Wang:KOL impact

      Concepts related to the work of other authors for whichfor which Kenneth K K Wang has influence:Barrett esophagus,  Esophageal adenocarcinoma,  Radiofrequency ablation,  Intestinal metaplasia,  Endoscopic resection,  Grade dysplasia,  Neoplastic progression.



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      Department of Gastroenterology, Mayo Clinic, Rochester, Minnesota. | Barrett's Esophagus Unit, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota. | Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minn

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