• Disease
  • Graves
  • Graves Orbitopathy
  • Maarten Ph Mourits

    Prominent publications by Maarten Ph Mourits

    KOL Index score: 13151

    PURPOSE: To describe the refraction and visual acuity outcomes of multifocal intraocular lens (IOL) implantation in patients with previous corneal refractive laser surgery for myopia.

    SETTING: Academic Medical Center, University of Amsterdam, Amsterdam, and Retina Total Eye Care, Driebergen, the Netherlands.

    DESIGN: Retrospective cohort study.

    METHODS: The 3-month results after implantation of a multifocal IOL (Acrysof Restor) in patients who had corneal refractive laser surgery for ...

    Also Ranks for: Intraocular Lens |  corneal refractive |  laser surgery |  visual acuity refraction |  multifocal iol
    KOL Index score: 12604

    PURPOSE: To compare the accuracy of different intraocular lens (IOL) calculation formulas available on the American Society of Cataract and Refractive Surgery (ASCRS) post-refractive surgery IOL power calculator for the prediction of multifocal IOL power after previous corneal refractive laser surgery for myopia.

    METHODS: An analysis and comparison were performed of the accuracy of three methods using surgically induced change in refraction (ie, Masket, Modified Masket, and Barrett ...

    Also Ranks for: Corneal Refractive |  barrett truek |  multifocal iol |  masket modified masket |  calculation formulas
    KOL Index score: 12525

    OBJECTIVE: Approximately 35% of patients with Graves' ophthalmopathy do not respond to immunosuppressive treatment. A possible explanation for this finding is that only patients with active ophthalmopathy respond to immunosuppressive treatment, whereas patients with fibrotic end stage disease do not. To distinguish between these two groups and to predict the outcome of immunosuppressive treatment, we developed a clinical activity score (CAS) based on four of the five classical signs of ...

    Also Ranks for: Clinical Activity Score |  patients graves ophthalmopathy |  immunosuppressive treatment |  therapeutic outcome |  retrobulbar irradiation
    KOL Index score: 11584

    PURPOSE: To determine prospectively the cataract-free interval (latency time) after total body irradiation (TBI) and bone marrow transplantation (BMT) and to assess accurately the final severity of the cataract.

    METHODS AND MATERIALS: Ninety-three of the patients who received TBI as a part of their conditioning regimen for BMT between 1982 and 1995 were followed with respect to cataract formation. Included were only patients who had a follow-up period of at least 23 months. TBI was ...

    Also Ranks for: Total Body Irradiation |  bone marrow transplantation |  steroid treatment |  patients tbi |  severity cataract
    KOL Index score: 11106

    OBJECTIVE: To evaluate the influence of strabismus surgery on quality of life (QoL) in Graves' orbitopathy (GO) patients.

    DESIGN: Prospective study of case series.

    METHODS: Consecutive GO-patients who were scheduled for their first strabismus surgery were included in the study. The patients completed the GO-QoL questionnaire within 3 months before the surgery and 2-4 months after the surgery. A complete orthoptic examination, including the field of binocular single vision (BSV), was ...

    Also Ranks for: Strabismus Surgery |  field bsv |  quality life |  visual functioning |  ophthalmopathy humans
    KOL Index score: 11051

    PURPOSE: To compare artificial eye amplitudes in patients who randomly received either a hydroxyapatite or an acrylic, scleral-covered spherical implant after enucleation.

    DESIGN: Randomized, controlled trial.

    PARTICIPANTS: Thirty-four consecutive patients who underwent enucleation because of an intraocular melanoma and 21 healthy control participants from the hospital staff.

    METHODS: Eligible patients randomly received a hydroxyapatite or an acrylic, scleral-covered spherical orbital ...

    Also Ranks for: Artificial Eye |  enucleation implants |  hydroxyapatite acrylic |  spherical implant |  aged orbital
    KOL Index score: 10837

    PURPOSE: The purpose of this study was to model the influence of cataract on Spectral Domain Optical Coherence Tomography (SDOCT) image quality and Retinal Nerve Fibre Layer (RNFL) thickness measurements.

    METHODS: SDOCT images, made with two different devices (3DOCT-1000, Topcon and Cirrus HD-OCT), before and after cataract surgery were compared and judged against measurements from normal subjects using artificial filters simulating the effects of cataract. Optical density of the images ...

    Also Ranks for: Optical Density |  coherence tomography |  retinal nerve |  rnfl thickness |  fibre layer
    KOL Index score: 10571

    OBJECTIVE: The Graves' ophthalmopathy quality of life questionnaire (GO-QOL) is the first instrument available to measure health-related quality of life (HRQL) of patients with Graves' ophthalmopathy. The main objective of this study was to define a minimal clinically important difference (MCID) in score on the GO-QOL that can be considered an important improvement in HRQL by examining changes in GO-QOL scores in patients who subjectively report improvement from their treatment. A ...

    Also Ranks for: Life Questionnaire |  patients goqol |  longitudinal validity |  graves ophthalmopathy |  qol scores
    KOL Index score: 10105

    BACKGROUND: Orbital fibroblasts are involved in the pathogenesis of Graves' ophthalmopathy (GO) by producing hyaluronan (HA), synthesized by three types of hyaluronan synthases (HAS1, HAS2, and HAS3). Thyrotropin receptors (TSHR) expressed in orbital fibroblasts activate the cyclic adenosine monophosphate (cAMP) pathway. Only sparse data are available at present supporting a role for TSHR activation in the regulation of HA in GO orbital fibroblasts. We hypothesize that TSHR activation, ...

    Also Ranks for: Orbital Fibroblasts |  hyaluronan production |  cyclic adenosine monophosphate |  ophthalmopathy patients |  tshr activation
    KOL Index score: 9993

    BACKGROUND: Optimal doses of i.v. glucocorticoids for Graves' orbitopathy (GO) are undefined.

    METHODS: We carried out a multicenter, randomized, double-blind trial to determine efficacy and safety of three doses of i.v. methylprednisolone in 159 patients with moderate to severe and active GO. Patients were randomized to receive a cumulative dose of 2.25, 4.98, or 7.47 g in 12 weekly infusions. Efficacy was evaluated objectively at 12 wk by blinded ophthalmologists and subjectively by ...

    Also Ranks for: Cumulative Dose |  active graves |  efficacy safety |  12 wk |  intravenous methylprednisolone
    KOL Index score: 9985

    Purpose Firstly, to assess the incidence of induced diplopia following orbital decompression in patients with Graves' orbitopathy. Secondly, to assess patient satisfaction after orbital decompression. Thirdly, to determine the factors that contribute to the variable reported incidence of diplopia complicating decompression surgery.Methods We present a retrospective analysis of the alterations of ocular motility in a consecutive series of 81 patients with Graves' orbitopathy who underwent ...

    Also Ranks for: Orbital Decompression |  incidence diplopia |  graves orbitopathy |  ocular motility |  disfiguring proptosis
    KOL Index score: 9900

    AIM: To provide age and gender-specific reference values for orbital fat and muscle volumes (MV) in Caucasian adults.

    PATIENTS AND METHODS: Computed tomographic scans of 160 orbits from 52 men and 55 women, aged 20-80 years, not affected by orbital disease were evaluated. Orbital bony cavity volume (OV), fat volume (FV) and MV were calculated by a previously validated method using the software program Mimics. Ratios of FV to OV and of MV to OV were determined.

    RESULTS: OV, FV and MV were ...

    Also Ranks for: Mv Ov |  orbital fat |  advancing age |  specific reference |  ratios fv
    KOL Index score: 9769

    It is uncertain what is the most appropriate medical therapy for patients with severe Graves' ophthalmopathy. Therefore, we carried out a single-blind, randomized clinical trial to compare the efficacy of prednisone with that of cyclosporine in 36 patients who had been euthyroid for at least two months. The two groups, each consisting of 18 patients, were similar in age, sex, and the duration and severity of ophthalmopathy. The initial dose of cyclosporine was 7.5 mg per kilogram of body ...

    Also Ranks for: Cyclosporine Patients |  severe graves |  12 weeks |  drug therapy |  prednisone treatment
    KOL Index score: 9656

    OBJECTIVE: Only a small percentage of Graves' ophthalmopathy (GO) patients develop optic neuropathy with impending loss of visual acuity. Therapy with methylprednisolone pulses is the treatment of first choice in severe and active GO patients. When the effect is insufficient, patients are usually treated with surgical decompression. We investigated whether surgery could become the first-line treatment, thus preventing treatment with steroids.

    DESIGN AND SUBJECTS: We performed a ...

    Also Ranks for: Visual Acuity |  graves ophthalmopathy |  optic neuropathy |  surgical decompression |  surgery patients
    KOL Index score: 9628

    OBJECTIVE: To determine management patterns among clinicians who treat patients with Graves' orbitopathy (GO) in Europe.

    DESIGN AND METHODS: Questionnaire survey including a case scenario of members of professional organisations representing endocrinologists, ophthalmologists and nuclear medicine physicians.

    RESULTS: A multidisciplinary approach to manage GO was valued by 96.3% of responders, although 31.5% did not participate or refer to a multidisciplinary team and 21.5% of patients ...

    Also Ranks for: Graves Orbitopathy |  questionnaire survey |  management patients |  surgical decompression |  multidisciplinary approach


    Maarten Ph Mourits: Influence Statistics

    Sample of concepts for which Maarten Ph Mourits is among the top experts in the world.
    Concept World rank
    16 mm agreement #1
    implanted seelens #1
    previous hyperopia #1
    straylight sn6ad1 #1
    orbital fat1 #1
    cst anticoagulation #1
    6 patients mp #1
    pearson hertel #1
    cas points #1
    secondary capsule #1
    orbitopathy percent #1
    intraocular lens opacifications #1
    detached aponeurosis #1
    eye motility duration #1
    predictable outcome eyes #1
    eye hospital zonnestraal #1
    50 graves patients #1
    straylight cataract surgery #1
    determinative factor respect #1
    multifocally implanted eye #1
    astigmatic components differences #1
    lid lengthening #1
    goqol tedqol #1
    sn6ad1 iol #1
    phacovitrectomy 133 eyes #1
    004d ± #1
    recurrence lid #1
    field bsv #1
    eyes proptosis #1
    volumes phantom #1
    qol tedqol #1
    intraocular marfan #1
    mf iol sn6ad1 #1
    straylight hyperopic #1
    type orbital decompression #1
    diffractive hydrophilic #1
    snellen iol #1
    translid approach #1
    follow pterygium #1
    postoperative straylight values #1
    interface debris eyes #1
    098d #1
    hughes tarsoconjunctival grafts #1
    surgery hyperopia #1
    vision bsv #1

    Key People For Graves Orbitopathy

    Top KOLs in the world
    Wilmar Maarten Wiersinga
    graves ophthalmopathy thyroid hormone fatty acids
    Maarten Ph Mourits
    graves orbitopathy intraocular lens strabismus surgery
    Claudio Marcocci
    primary hyperparathyroidism graves orbitopathy orbital radiotherapy
    George J Kahaly
    graves disease retrobulbar fibroblasts polyglandular autoimmunity
    Luigi BARTALENA,
    graves disease orbital radiotherapy radioiodine therapy
    Lelio Baldeschi
    graves orbitopathy orbital decompression exophthalmos reduction

    Maarten Ph Mourits:Expert Impact

    Concepts for whichMaarten Ph Mouritshas direct influence:Graves orbitopathy,  Graves ophthalmopathy,  Epithelial ingrowth,  Intraocular lens,  Strabismus surgery,  Orbital decompression,  Coronal approach,  Optical density.

    Maarten Ph Mourits:KOL impact

    Concepts related to the work of other authors for whichfor which Maarten Ph Mourits has influence:Graves ophthalmopathy,  Thyroid eye disease,  Orbital decompression,  Visual acuity,  Optic nerve,  Intraocular lens,  Extraocular muscles.



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    Department of Ophthalmology, Amsterdam UMC (location AMC), University of Amsterdam, the Netherlands. | Department of Ophthalmology Netherlands, Amsterdam University Medical Center, Academic Medical Center, University of Amsterdam, the Netherlands. |