Shih‐Wei Wang

Shih‐Wei Wang

Department Of Biological Sciences, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan, Roc.

Direct Impact

Concepts for which Shih‐Wei Wang has direct influence:

chondrosarcoma cells
vegf expression
vascular endothelial growth factor
prostate cancer
synovial fibroblasts
endothelial progenitor
hepatocellular carcinoma

External impact

Concepts related to the work of other authors for which Shih‐Wei Wang has influence:

endothelial progenitor cells
wnt1-inducible signaling pathway protein-1
gastric cancer
growth factor
synovial fibroblasts
p53 gene
sh2 domain

Prominent publications by Shih‐Wei Wang

KOL-Index: 72 Lymphatic metastasis is a biological procedure associated with the pathogenesis of several diseases, especially in tumor metastasis. Therefore, regulation of lymphangiogenesis has become a promising strategy for cancer therapy. In this study, we aimed to investigate the anti-lymphangiogenic effect of heteronemin (SP-1) isolated from the sponge Hyrtios sp. in vitro and in vivo. Human ...
Known for
Lymphangiogenesis-Associated | Tumor Metastasis | Lymphangiogenic | Mmp-9 Cadherin
KOL-Index: 45 Sorafenib is the only FDA approved drug for the treatment of advanced hepatocellular carcinoma (HCC) and other malignancies. Studies indicate that TGF-β signalling is associated with tumour progression in HCC. Autocrine and paracrine TGF-β promotes tumour growth and malignancy by inducing epithelial-mesenchymal transition (EMT). Sorafenib is believed to antagonize tumour progression by ...
Known for
Tβrii Localized | Sorafenib Induced | Paracrine Tgf-Β | Hepatic Stellate Cells
KOL-Index: 45 Lymphangiogenesis is an important biological process associated with cancer metastasis. The development of new drugs that block lymphangiogenesis represents a promising therapeutic strategy. Marine fungus-derived compound phomaketide A, isolated from the fermented broth of Phoma sp. NTOU4195, has been reported to exhibit anti-angiogenic and anti-inflammatory effects. However, its ...
Known for
Pkcδ Enos | Inhibitors Lecs | Cells Lymphangiogenesis | Phomaketide Inhibits
KOL-Index: 43 A new indoleglycerol, designated as arecine (1), and twenty‐three known diketopiperazines 2–24 were isolated from the endophytic fungus Diaporthe arecae associated with mangrove Kandelia obovate. Structures of all secondary metabolites 1–24 were identified on the basis of their spectrometric data, especially the nuclear magnetic resonance, optical rotation, and mass data. The absolute ...
Known for
Spectrometric | Electronic Circular Dichroism | Tube Formation | Mild Anti‐angiogenic Activity
KOL-Index: 42 Chondrosarcoma is a malignant bone tumor that is characterized by high metastatic potential and marked resistance to radiation and chemotherapy. The knowledge that adipokines facilitate the initiation, progression, metastasis, and treatment resistance of various tumors has driven several in vitro and in vivo investigations into the effects of adipokines resistin, leptin, and adiponectin upon ...
Known for
Visfatin-Induced Stimulation | Visfatin Enhanced Lung Metastasis | Malignant Bone Tumor | Adipokines
KOL-Index: 36 Qin Pi (Fraxinus chinensis Roxb.) is commercially used in healthcare products for the improvement of intestinal function and gouty arthritis in many countries. Three new secoiridoid glucosides, (8E)-4''-O-methylligstroside (1), (8E)-4''-O-methyldemethylligstroside (2), and 3'',4''-di-O-methyl-demethyloleuropein (3), have been isolated from the stem bark of Fraxinus chinensis, together with ...
Known for
Tnf Il-6 | Ic50 Addition | Inhibited Fmlp | Methylligstroside
KOL-Index: 35 Osteoarthritis (OA) pannus contains a network of neovascularization that is formed and maintained by angiogenesis, which is promoted by vascular endothelial growth factor (VEGF). Bone marrow-derived endothelial progenitor cells (EPCs) are involved in VEGF-induced vessel formation in OA. The adipokine visfatin stimulates the release of inflammatory cytokines during OA progression. In this ...
Known for
Bone Marrow-Derived Endothelial Progenitor | Expression Epc | Sirnas | Mir-485-5p Synthesis
KOL-Index: 32 Angiogenesis is a critical process in the formation of new capillaries and a key participant in rheumatoid arthritis (RA) pathogenesis. The chemokine (C-X-C motif) ligand 13 (CXCL13) plays important roles in several cellular functions such as infiltration, migration, and motility. We report significantly higher levels of CXCL13 expression in collagen-induced arthritis (CIA) mice compared ...
Known for
Arthritis Angiogenesis | Shrna | Cellular Functions | Endothelial Progenitor Homing
KOL-Index: 31 The recruitment of bone marrow-derived endothelial progenitor cells (EPCs) facilitates physiological and pathological processes involved in new blood vessel synthesis. Glucocerebroside, an extract of Cordyceps militaris, inhibits inflammatory cytokine production and monocyte migration, although its anti-angiogenic properties in human EPCs has remained largely unknown up until now. We ...
Known for
Formation Induced | Reduces Vessel
KOL-Index: 30 Zinc oxide nanoparticles (ZnO-NPs) are increasingly used in sunscreens, food additives, pigments, rubber manufacture, and electronic materials. Several studies have shown that ZnO-NPs inhibit cell growth and induce apoptosis by the production of oxidative stress in a variety of human cancer cells. However, the anti-cancer property and molecular mechanism of ZnO-NPs in human gingival squamous ...
Known for
Zebrafish Xenograft Model | Zno-Nps Induced Growth Inhibition | Sub-G1 Phase Accumulation | Concentration-Dependent Manner

Department of Biological Sciences, National Sun Yat-sen University, Kaohsiung 80424, Taiwan, ROC.

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