• KOLs Community
    • Kawasaki Disease
    • Prevalence And...
    • Key People For Kawasaki Disease

      Top KOLs in the world
      JANE C Burns
      kawasaki disease infective endocarditis kd patients
      Jane W Newburger
      kawasaki disease great arteries infective endocarditis
      Stanford T Shulman
      kawasaki disease rheumatic fever infective endocarditis
      Masato Takahashi
      kawasaki disease infective endocarditis heart association
      Anne Heitzman Rowley
      kawasaki disease infective endocarditis acute kd
      infective endocarditis heart association kawasaki disease

      Prevalence and characteristics of arthritis in Kawasaki disease: a Chinese cohort study


      Arthritis is a major complication of Kawasaki disease (KD). The aims of this study were to define the frequency and the clinical characteristics of arthritis in KD in China and to analyze the relation between arthritis and coronary outcome in KD. We included 1420 KD patients followed at Jiangxi Children’s Hospital from January 2014 to December 2017. Demographic, clinical and laboratory features of KD were analyzed. Among the 1420 patients enrolled, 151 had arthritis. The median age of KD patients with arthritis was 29 months and older than those without arthritis (20 months). Of the 151 patients developed arthritis, 101 patients (66.9%) had oligoarticular involvement and 50 patients (33.1%) had polyarticular involvement. Early-onset and late-onset arthritis were, respectively, observed in 123 (81.45%) and 28 (18.54%) patients. The KD patients with arthritis had significantly increased levels of inflammatory markers, and we observed a higher incidence rate of coronary artery aneurysms among those with arthritis (7.28%) compared to those without arthritis (2.75%) (p = 0.003), but the prevalence of coronary artery lesions (CALs) was similar in the two groups. The arthritis in KD was self-limited, left no sequelae and did not require additional medications. KD patients with arthritis were more likely to get coronary artery aneurysms than the patients without arthritis, so examination of joints in KD was necessary.

      Sign-in to see all concepts, it's free!


    Download on the App StoreGet it on Google Play

    Copyright © 2023 - KOL means Key Opinion Leaders .

    KOL does not provide medical advice, diagnosis or treatment.