• Knee Osteoarthritis
    • David John Hunter
    • David John Hunter: Influence Statistics

      David John Hunter

      David John Hunter

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      Rheumatology Dept., Royal North Shore Hosp., Sydney, Australia | Sydney Musculoskeletal Health, Kolling Institute of Medical Research, University of Sydney, Australia. | The ...

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      David John Hunter:Expert Impact

      Concepts for whichDavid John Hunterhas direct influence:Knee osteoarthritis,Knee pain,Cartilage loss,Osteoarthritis initiative,Osteoarthritis knee,Pain exacerbation,Recurrent gout attacks,Bone attrition.

      David John Hunter:KOL impact

      Concepts related to the work of other authors for whichfor which David John Hunter has influence:Knee osteoarthritis,Type 2 diabetes,Articular cartilage,Physical activity,Subchondral bone,Chronic pain,Hyaluronic acid.

      KOL Resume for David John Hunter


      Rheumatology Dept., Royal North Shore Hosp., Sydney, Australia

      Clinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou


      Royal North Shore Hospital, St Leonards, NSW, Australia

      Clinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou, China

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      Sample of concepts for which David John Hunter is among the top experts in the world.
      Concept World rank
      medial tibia pabmd #1
      morphology ptfj #1
      segmental wedging #1
      risk factors idd #1
      imdbl jsn #1
      knees early stage #1
      fixedlocation jsw #1
      symptoms imaging severity #1
      nocturnal risk #1
      occupational exposures knee #1
      meniscus extrusion srm #1
      irregular types #1
      major constituents supplements #1
      odds knee #1
      mrioutcomes #1
      biomarkers knee #1
      knee study #1
      tibial bone perfusion #1
      24 months 24month #1
      kgm s3 #1
      roames #1
      posterior degeneration #1
      actrn12617000853347 #1
      illness knee #1
      individuals thumb base #1
      function foot pain #1
      stem cell injections #1
      odds incident roa #1
      education comparator #1
      intrasubstance signal #1
      total epiphyseal bmd #1
      online sgs osgs #1
      hip muscles symptoms #1
      associations ultrasound #1
      predictive performance participants #1
      longer diffuse #1
      service delivery partner #1
      foundation national institute #1
      hip osteoarthritis tests #1
      knee replacement knees #1
      meniscal abnormalities knee #1
      meniscus subluxation #1
      workplace pa #1
      disruptive digital #1
      joint alignment severity #1
      supplement combination #1
      klg3 participants #1
      medial tibiofemoral #1
      radiographic knee p0 #1
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      Prominent publications by David John Hunter

      KOL-Index: 22727

      IMPORTANCE: Knee osteoarthritis (OA), a common cause of chronic pain and disability, has biomechanical and inflammatory origins and is exacerbated by obesity.

      OBJECTIVE: To determine whether a ≥10% reduction in body weight induced by diet, with or without exercise, would improve mechanistic and clinical outcomes more than exercise alone.

      DESIGN, SETTING, AND PARTICIPANTS: Single-blind, 18-month, randomized clinical trial at Wake Forest University between July 2006 and April 2011. The ...

      Known for Exercise Diet | Obese Adults | Knee Osteoarthritis | Clinical Trial | 18 Months
      KOL-Index: 22557

      BACKGROUND: Paracetamol (acetaminophen) is vastly recommended as the first-line analgesic for osteoarthritis of the hip or knee. However, there has been controversy about this recommendation given recent studies have revealed small effects of paracetamol when compared with placebo. Nonetheless, past studies have not systematically reviewed and appraised the literature to investigate the effects of this drug on specific osteoarthritis sites, that is, hip or knee, or on the dose ...

      Known for Hip Osteoarthritis | Pain Function | Paracetamol Placebo | Risk Bias | 0 100
      KOL-Index: 22533

      PURPOSE: As a prelude to developing updated, evidence-based, international consensus recommendations for the management of hip and knee osteoarthritis (OA), the Osteoarthritis Research Society International (OARSI) Treatment Guidelines Committee undertook a critical appraisal of published guidelines and a systematic review (SR) of more recent evidence for relevant therapies.

      METHODS: Sixteen experts from four medical disciplines (primary care two, rheumatology 11, orthopaedics one and ...

      Known for Critical Appraisal | Knee Osteoarthritis | Treatment Guidelines | Oarsi Recommendations | Management Hip
      KOL-Index: 22509

      BACKGROUND: Femoroacetabular impingement syndrome is an important cause of hip pain in young adults. It can be treated by arthroscopic hip surgery, including reshaping the hip, or with physiotherapist-led conservative care. We aimed to compare the clinical effectiveness of hip arthroscopy with best conservative care.

      METHODS: UK FASHIoN is a pragmatic, multicentre, assessor-blinded randomised controlled trial, done at 23 National Health Service hospitals in the UK. We enrolled patients ...

      Known for Hip Arthroscopy | Impingement Syndrome | Uk Fashion | Conservative Treatment | Controlled Trial
      KOL-Index: 19690

      PURPOSE: To develop concise, patient-focussed, up to date, evidence-based, expert consensus recommendations for the management of hip and knee osteoarthritis (OA), which are adaptable and designed to assist physicians and allied health care professionals in general and specialist practise throughout the world.

      METHODS: Sixteen experts from four medical disciplines (primary care, rheumatology, orthopaedics and evidence-based medicine), two continents and six countries (USA, UK, France, ...

      Known for Consensus Guidelines | Knee Osteoarthritis | Management Hip | Based Evidence | Chondroitin Sulphate
      KOL-Index: 16212

      OBJECTIVE: To investigate the association between knee pain and signs of inflammation in the infrapatellar fat pad (IPFP) in obese patients with knee osteoarthritis (KOA).

      DESIGN: In a cross-sectional setting, 3-T conventional contrast-enhanced (CE) magnetic resonance imaging (MRI) and dynamic contrast-enhanced (DCE)-MRI of KOA were analysed to quantify the extent of inflammation in the IPFP, and correlated (Spearman's rank correlation) to pain and other symptoms assessed via the Knee ...

      Known for Knee Pain | Infrapatellar Fat Pad | Magnetic Resonance | Koa Ipfp | Dynamic Contrast
      KOL-Index: 15817

      OBJECTIVE: To determine the relationship between radiographic progression of joint space narrowing and cartilage loss on magnetic resonance imaging (MRI) in patients with symptomatic knee osteoarthritis (OA), and to investigate the location of MRI-based cartilage loss in the knee and its relation to radiographic progression.

      METHODS: Two hundred twenty-four men and women (mean age 66 years) were studied. Radiographs and MRI of the more symptomatic knee were obtained at baseline and at ...

      Known for Cartilage Loss | Radiographic Progression | Magnetic Resonance Imaging | Knee Osteoarthritis | Joint Space Narrowing
      KOL-Index: 15662

      AIM: MRI provides unparalleled visualisation of all the anatomical structures involved in the osteoarthritis (OA) process. There is a need for reliable methods of quantifying abnormalities of these structures. The aim of this work was to assess the reliability of a novel MRI scoring system for evaluating OA of the knee and explore the validity of the bone marrow lesion (BML) scoring component of this new tool.

      METHODS: After review of the relevant literature, a collaborative group of ...

      Known for Osteoarthritis Mri | Knee Score | Bone Marrow | Bloks Reliability | Cartilage Loss
      KOL-Index: 15349

      OBJECTIVE: Bone marrow lesions are associated with pain and compartment-specific progression of joint space narrowing in patients with knee osteoarthritis (OA). Bone marrow lesions occur in regions under increased loading, and excess loading produces increased bone mineral density (BMD). The ratio of BMD in the medial tibial plateau compared with that in the lateral tibial plateau (M:L BMD ratio) reflects loading in the knee. Therefore, we hypothesized that a higher M:L BMD ratio would ...

      Known for Bone Marrow | Bmd Ratio | Medial Lateral | Lesions Knee | Ors Highest Quartile
      KOL-Index: 15215

      We used data from a longitudinal observation study to determine whether markers of cartilage turnover could serve as predictors of cartilage loss on magnetic resonance imaging (MRI). We conducted a study of data from the Boston Osteoarthritis of the Knee Study (BOKS), a completed natural history study of knee osteoarthritis (OA). All subjects in the study met American College of Rheumatology criteria for knee OA. Baseline and follow-up knee magnetic resonance images were scored for ...

      Known for Cartilage Loss | Knee Osteoarthritis | Resonance Imaging | Gender Bmi | Baseline Levels
      KOL-Index: 14940

      BACKGROUND: Obesity and knee osteoarthritis are among the most frequent chronic conditions affecting Americans aged 50 to 84 years.

      OBJECTIVE: To estimate quality-adjusted life-years lost due to obesity and knee osteoarthritis and health benefits of reducing obesity prevalence to levels observed a decade ago.

      DESIGN: The U.S. Census and obesity data from national data sources were combined with estimated prevalence of symptomatic knee osteoarthritis to assign persons aged 50 to 84 years ...

      Known for Knee Osteoarthritis | Adjusted Life | Aged Obesity | Prevalence Quality | Hispanic Americans
      KOL-Index: 14607

      OBJECTIVE: To investigate the association of cartilage thickness change over 24 months, as determined by magnetic resonance imaging (MRI), with knee osteoarthritis (OA) progression at 24-48 months.

      METHODS: This nested case-control study included 600 knees with a baseline Kellgren/Lawrence (K/L) grade of 1-3 from 600 Osteoarthritis Initiative (OAI) participants. Case knees (n = 194) had both medial tibiofemoral radiographic joint space loss (≥0.7 mm) and a persistent increase in the ...

      Known for Cartilage Thickness | Osteoarthritis Progression | 24 Months | Imaging Biomarker | Case Status
      KOL-Index: 14475

      OBJECTIVE: To examine the relationship between longitudinal fluctuations in synovitis with change in pain and cartilage in knee osteoarthritis.

      METHODS: Study subjects were patients 45 years of age and older with symptomatic knee osteoarthritis from the Boston Osteoarthritis of the Knee Study. Baseline and follow-up assessments at 15 and 30 months included knee magnetic resonance imaging (MRI), BMI and pain assessment (VAS) over the last week. Synovitis was scored at 3 locations ...

      Known for Cartilage Loss | Knee Osteoarthritis | Synovitis Pain | Magnetic Resonance | 3 Locations
      KOL-Index: 14211

      BACKGROUND CONTEXT: Although the role of radiographic abnormalities in the etiology of nonspecific low back pain (LBP) is unclear, the frequent identification of these features on radiologic studies continues to influence medical decision making.

      PURPOSE: The primary purposes of the study were to evaluate the prevalence of lumbar spine degeneration features, evaluated on computed tomography (CT), in a community-based sample and to evaluate the association between lumbar spine ...

      Known for Spinal Degeneration | Computed Tomography | Age Prevalence | Facet Joint | Association Lbp
      KOL-Index: 13921

      STUDY DESIGN: Cross-sectional study.

      OBJECTIVES: To determine prevalence rates of spondylolysis, isthmic, and degenerative spondylolisthesis in an unselected adult community-based population; and to evaluate the association of spondylolysis, isthmic, and degenerative spondylolisthesis with low back pain (LBP).

      SUMMARY OF BACKGROUND DATA: Spondylolysis and spondylolisthesis are prevalent in the general population; however, the relationship between these conditions and LBP is ...

      Known for Spondylolysis Spondylolisthesis | Lbp Association | Low Pain | Framingham Heart Study | Background Data

      Key People For Knee Osteoarthritis

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      Rheumatology Dept., Royal North Shore Hosp., Sydney, Australia | Sydney Musculoskeletal Health, Kolling Institute of Medical Research, University of Sydney, Australia. | The Univ. of Sydney, Sydney, Australia | Institute of Bone and Joint Research, K

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