Nortina Shahrizaila: Influence Statistics

Nortina Shahrizaila

Nortina Shahrizaila

Department of Neurology, University of Malaya, Kuala Lumpur, Malaysia | Neurology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, ...

Nortina Shahrizaila: Expert Impact

Concepts for which Nortina Shahrizaila has direct influence: Barré syndrome , Amyotrophic lateral sclerosis , Fisher syndrome , Neuromuscular ultrasound , Nerve ultrasound , Brighton criteria , Guillainbarré syndrome .

Nortina Shahrizaila: KOL impact

Concepts related to the work of other authors for which for which Nortina Shahrizaila has influence: Barré syndrome , Amyotrophic lateral sclerosis , Zika virus , Chronic inflammatory , Patients gbs , Intravenous immunoglobulin , Molecular mimicry .

KOL Resume for Nortina Shahrizaila


Department of Neurology, University of Malaya, Kuala Lumpur, Malaysia


Department of Medicine, University of Malaya Medical Center, Kuala Lumpur, Malaysia


author for electrodiagnostic medicine

Neurology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. Electronic address:


Division of Neurology, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

From the Departments of Neurology (C.V., A.Y.D., B.C.J.) and Immunology (B.C.J.), Erasmus MC, University Medical Center Rotterdam, the Netherlands; Department of Neurology (G.G.), University Hospital of Modena, Italy; Department of Neurology (A.D., H.J.W.), University of Glasgow, UK; Department of Neurology (W.W.), University of Vermont Medical Center, Burlington; Department of Clinical Neurophysiology (Y.P.), Reference Centre for NMD, Nantes University Hospital, France; Department of Medicine (N.S.), University of Malaya, Kuala Lumpur, Malaysia; Department of Neurology (S.K.), Kindai University Faculty of Medicine, Osaka, Japan; Department of Neurology (H.C.L.), Universitätsklinikum Köln, Germany; Department of Neurology (T.H.), Aarhus University Hospital, Denmark; Department of Neurology (S.M.), Hospital de Pediatría J.P. Garrahan, Buenos Aires, Argentina; Department of Neurology (P.V.d.B.), University Hospital St-Luc, University of Louvain, Brussels, Belgium; and Department of Neurology (D.R.C.), Johns Hopkins University School of Medicine, Baltimore, MD.

Department of Medicine, University of Malaya, Kuala Lumpur, Wilayah Persekutuan, Malaysia


Brain and Mind Centre, Sydney Medical School, University of Sydney, Sydney, NSW, Australia.

Department of Medicine, University of Malaya, Lembah Pantai, 50603, Kuala Lumpur, Malaysia

Royal Prince Alfred Hospital Sydney, Sydney, New South Wales, Australia


University Malaya Medical Center, Department of Medicine, Kuala Lumpur, Malaysia


University of Malaya Department of Medicine, Faculty of Medicine Kuala Lumpur Malaysia


Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.


Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia


University of Malaya Division of Neurology Faculty of Medicine Kuala Lumpur Malaysia


Department of Medicine, University of Malaya, Malaysia


University of Malaya, Faculty of Medicine, Lembah Pantai, 50603 Kuala Lumpur, Malaysia


Division of Neurology, Department of Medicine, Faculty of Medicine, University of Malaya, Lembah Pantai, 59100 Kuala Lumpur, Malaysia


Department of Respiratory Medicine, Queen’s Medical Centre


Department of Neurology, Queen's Medical Centre, Nottingham NG7 1UH, UK.


From the Department of Neurology (Drs. Shahrizaila and Wills), Queen’s Medical Centre, University Hospital NHS Trust, Nottingham, UK; and Department of Histopathology (Dr. Lowe), Queen’s Medical Centre, Nottingham, UK.

Prominent publications by Nortina Shahrizaila

KOL-Index: 13914 . Signaling through the store-operated Ca(2+) release-activated Ca(2+) (CRAC) channel regulates critical cellular functions, including gene expression, cell growth and differentiation, and Ca(2+) homeostasis. Loss-of-function mutations in the CRAC channel pore-forming protein ORAI1 or the Ca(2+) sensing protein stromal interaction molecule 1 (STIM1) result in severe immune dysfunction and ...
Known for Congenital Miosis | Crac Channel | Stormorken Syndrome | Stim1 Orai1
KOL-Index: 9782 . In the 1950s, Bickerstaff and Fisher independently described cases with a unique presentation of ophthalmoplegia and ataxia. The neurological features were typically preceded by an antecedent infection and the majority of patients made a spontaneous recovery. In the cases with Bickerstaff brainstem encephalitis, there was associated altered consciousness and in some, hyperreflexia, in ...
Known for Fisher Syndrome | Brainstem Encephalitis | Gq1b Antibody | Acute Ophthalmoparesis
KOL-Index: 8576 . Guillain-Barré syndrome is a heterogeneous disorder regarding the clinical presentation, electrophysiological subtype and outcome. Previous single country reports indicate that Guillain-Barré syndrome may differ among regions, but no systematic comparative studies have been conducted. Comparative studies are required to identify factors determining disease susceptibility, variation and ...
Known for Barré Syndrome | Child Child | Clinical Presentation | Electrophysiological Subtype
KOL-Index: 8231 . The electrodiagnosis of Guillain-Barré syndrome (GBS) can be broadly divided into acute inflammatory demyelinating polyneuropathy (AIDP) and acute motor axonal neuropathy (AMAN). Fisher syndrome (FS) is a variant of GBS, although the underlying neuropathy of FS has yet to be established. Serial nerve conduction studies (NCS) can provide further insight into the likely pathophysiology by ...
Known for Fisher Syndrome | Patients Gbs | Conduction Studies | Serial Ncs
KOL-Index: 7974 . Guillain-Barré syndrome (GBS) is a rare, but potentially fatal, immune-mediated disease of the peripheral nerves and nerve roots that is usually triggered by infections. The incidence of GBS can therefore increase during outbreaks of infectious diseases, as was seen during the Zika virus epidemics in 2013 in French Polynesia and 2015 in Latin America. Diagnosis and management of GBS can be ...
Known for Management Gbs | Barré Syndrome | Clinical Presentation | Peripheral Nerves
KOL-Index: 7551 . Background/Aims: This study aimed to investigate the validity and reliability of the Malay version of Addenbrooke's Cognitive Examination III (ACE-III) for detecting mild cognitive impairment (MCI) and dementia. Methods: A total of 152 participants (dementia = 53, MCI = 38, controls = 61) were recruited from two teaching hospitals. The Malay version of ACE-III was translated following the ...
Known for Mild Cognitive Impairment | Aceiii Dementia | Cognitive Examination | Iii Ace
KOL-Index: 7398 . OBJECTIVE: Recent studies have advocated the use of serial nerve conduction studies (NCS) in the electrodiagnosis of Guillain-Barré syndrome (GBS). The current study aims to elucidate when and how frequent NCS can be performed to reflect the disease pathophysiology. METHODS: A prospective study of GBS patients documenting the initial and final electrodiagnoses following serial NCS ...
Known for Barré Syndrome | Conduction Studies | Gbs Patients | Electrodiagnosis Guillain
KOL-Index: 7177 . Peripheral neuropathy is a known manifestation of systemic lupus erythematosus. However, the association of primary autoimmune inflammatory neuropathies such as chronic inflammatory demyelinating polyneuropathy (CIDP) with SLE is uncommon. We report a 26-year-old man who simultaneously presented with severe CIDP and photosensitive rash, but was unresponsive to intravenous immunoglobulin ...
Known for Chronic Inflammatory | Systemic Lupus Erythematosus | Cidp Sle | Demyelinating Polyneuropathy
KOL-Index: 7150 . OBJECTIVE: To comprehensively investigate the relationship between antibodies to single glycolipids and their complexes and Guillain-Barré syndrome subtypes and clinical features. METHODS: In acute sera from 199 patients with Guillain-Barré syndrome, immunoglobulin G (IgG) antibodies to glycolipids and ganglioside complexes were tested using ELISA against individual antigens from single ...
Known for Immunoglobulin Igg | Ganglioside Complexes | Acute Motor | Axonal Neuropathy
KOL-Index: 6125 . Molecular mimicry between self and microbial components has been proposed as the pathogenic mechanism of autoimmune diseases, and this hypothesis is proven in Guillain-Barré syndrome. Guillain-Barré syndrome, the most frequent cause of acute neuromuscular paralysis, sometimes occurs after Campylobacter jejuni enteritis. Gangliosides are predominantly cell-surface glycolipids highly ...
Known for Molecular Mimicry | Barré Syndrome | Human Autoimmune | Animal Model
KOL-Index: 6119 . BACKGROUND AND PURPOSE: Anti-GQ1b antibodies have been found in patients with Miller Fisher syndrome as well as its related conditions. Our aim was to identify the mechanism by which autoantibodies produce various clinical presentations in 'anti-GQ1b antibody syndrome'. METHODS: Immunoglobulin G antibodies to ganglioside complex (GSC) of GQ1b or GT1a with GM1, GD1a, GD1b or GT1b were ...
Known for Clinical Spectrum | Anti Gq1b | Ganglioside Complex | Miller Fisher Syndrome
KOL-Index: 6087 . OBJECTIVE: To optimize the electrodiagnosis of Guillain-Barré syndrome (GBS) subtypes at first study. METHODS: The reference electrodiagnosis was obtained in 53 demyelinating and 45 axonal GBS patients on the basis of two serial studies and results of anti-ganglioside antibodies assay. We retrospectively employed sparse linear discriminant analysis (LDA), two existing electrodiagnostic ...
Known for Electrodiagnostic Accuracy | Syndrome Subtypes | Criteria Sets | Serial Studies
KOL-Index: 5959 . OBJECTIVE: To assess the longitudinal changes of nerve ultrasound in Guillain-Barré syndrome (GBS) patients. METHODS: We prospectively recruited 17 GBS patients and 17 age and gender-matched controls. Serial studies of their nerve conduction parameters and nerve ultrasound, documenting the cross-sectional areas (CSA), were performed at admission and repeated at several time points ...
Known for Nerve Ultrasound | Barré Syndrome | Disease Onset | Conduction Peripheral
KOL-Index: 5622 . Intravenous immunoglobulin (IVIG) is the first line treatment for Guillain-Barré syndrome and multifocal motor neuropathy, which are caused by anti-ganglioside antibody-mediated complement-dependent cytotoxicity. IVIG has many potential mechanisms of action, and sialylation of the IgG Fc portion reportedly has an anti-inflammatory effect in antibody-dependent cell-mediated cytotoxicity ...
Known for Complement Deposition | Ivig Treatment | Intravenous Immunoglobulin | Anti Ganglioside
KOL-Index: 5397 . Our objective was to determine the survival and prognostic factors of motor neuron disease (MND) in a multi-ethnic cohort of Malaysian patients. All patients seen at a university medical centre between January 2000 and December 2009 had their case records reviewed for demographic, clinical and follow-up data. Mortality data, if unavailable from records, were obtained by telephone interview ...
Known for Motor Neuron Disease | Age Onset | Asian Population | Mortality Data

Key People For Barré Syndrome

Top KOLs in the world
Richard A C Hughes
plasma exchange chronic inflammatory intravenous immunoglobulin
David Reid Cornblath
chronic inflammatory barré syndrome multifocal motor
Pieter Antoon van Doorn
pompe disease chronic inflammatory intravenous immunoglobulin
Nobuhiro Yuki
barré syndrome campylobacter jejuni chronic inflammatory
Bart Casper Jacobs
barré syndrome campylobacter jejuni gbs patients
Arthur K Asbury
axolemmal fraction nerve biopsy genetic testing

Department of Neurology, University of Malaya, Kuala Lumpur, Malaysia | Neurology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia | Division of Neurology, Department of Medicine, University of Malaya, K