 | Stanley L Inhorn |
Prominent publications by Stanley L Inhorn
Hypophagia-induced weight loss in mice, rats, and guinea pigs treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin
[ PUBLICATION ]
C57BL/6 mice treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD; 360 micrograms/kg) displayed a significant reduction in feed intake and body weight until just before death, when they developed ascites and subcutaneous edema. This caused body weight of the mice that died to suddenly increase during the terminal stage of toxicity. TCDD-treated mice that survived did not develop ascites or edema, and maintained a body weight that was slightly less than that of pair-fed mice. Cumulative ...
| Also Ranks for: Guinea Pigs | weight loss | rats treated | pair fed | water intake |
Relationship of the wasting syndrome to lethality in rats treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin
[ PUBLICATION ]
Young adult male Sprague-Dawley rats treated with a LD95 dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exhibited a progressive reduction in feed intake and body weight until death occurred 15 to 32 days post-treatment. The time course and magnitude of weight loss and lethality of pair-fed control rats were essentially identical to that of TCDD-treated rats with each pair-fed control animal dying within 3 days of its TCDD-treated partner. Body composition analysis of the dead animals ...
| Also Ranks for: Rats Treated | wasting syndrome | pair fed | weight loss | inbred strains |
Thyroid status and thermogenesis in rats treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin
[ PUBLICATION ]
Several key aspects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) toxicity resemble the effects of hypothyroidism, while in other ways the toxic responses are characteristics of hyperthyroidism. Whether thyroid dysfunction plays a role in TCDD toxicity remained unknown, however. We therefore determined the dose-related effects of TCDD treatment on plasma concentrations of L-thyroxine (T4), 3,5,3'-triiodo-L-thyronine (T3), and thyroid-stimulating hormone (TSH), and compared these changes ...
| Also Ranks for: Thyroid Status | tcdd treatment | plasma concentrations | rats treated | toxic responses |
In November 2004, the Association of Public Health Laboratories (APHL) conducted a Comprehensive Laboratory Services Survey of State Public Health Laboratories (SPHLs) in order to establish the baseline data necessary for Healthy People 2010 Objective 23-13. This objective aims to measure the increase in the proportion of health agencies that provide or assure access to comprehensive laboratory services to support essential public health services. This assessment addressed only SPHLs and ...
| Also Ranks for: Laboratory Services | public health | disease control | 11 core functions | survey state |
Fluorescent in situ hybridization (FISH) with alpha satellite DNA probes for chromosomes 11 and X were applied to normal, atypical, and dysplastic cervical-vaginal cytology smears to evaluate the detection of hyperploidy in suspected abnormal cells. Forty-six cases were obtained from fixed archival material. Eight cases with a morphological diagnosis of within normal limits (WNL) were directly selected to use as controls. The other 38 cases were blinded as study cases. These included ...
| Also Ranks for: Situ Hybridization | cervical dysplasia | squamous cells | human pair | intraepithelial neoplasia |
A woman with multiple congenital anomalies, mental retardation and mosaicism for an unusual translocation chromosome t (6;19)
[ PUBLICATION ]
A mentally retarded woman with multiple congenital anomalies is described.
Her fibroblasts had a normal female chromosome complement, but in virtually all lymphocytes there were only 45 chromosomes, one no. 6 and one no. 19 having joined with their short arms. The two terminal deletions may have been submicroscopically small. Whether they had caused the clinical anomalies remains an open question.
The translocation chromosome had only the primary constriction of no. 19, although no ...
| Also Ranks for: Translocation Chromosome | mental retardation | congenital anomalies | 19 6 | primary constriction |
A syndrome of multiple developmental defects including polycystic kidneys and intrahepatic biliary dysgenesis in 2 siblings
[ PUBLICATION ]
Two siblings were found to have a syndrome consisting of at least 13 comparable developmental defects including hypotonia, high forehead, camptodactyly, polycystic kidneys, intrahepatic biliary dysgenesis, incomplete descent of the gonads, and minor defects of the eyes, ears, palate, and hands. The patients failed to thrive, became jaundiced, and died in early infancy. The mother did not take any medication during either pregnancy. Cytologic studies did not reveal a chromosomal ...
| Also Ranks for: Polycystic Kidneys | intrahepatic biliary dysgenesis | female heart defects | early infancy | publication bile ducts |
Use of trypsin-modified human erythrocytes in rubella hemagglutination-inhibition testing.
[ PUBLICATION ]
A method of treating human erythrocytes with trypsin has been modified and found to be an efficient and practical indicator system for the rubella hemagglutination-inhibition test. Both the trypsin-treated human cells and the widely used, newborn chicken erythrocytes were used in comparative testing of 464 selected diagnostic rubella serums. Results with each cell system were essentially the same. The trypsin treatment procedure has been found to be relatively simple, and with our ...
| Also Ranks for: Rubella Hemagglutination | human erythrocytes | inhibition test | abo blood | evaluation studies |
OBJECTIVES: To assess Healthy People 2010 Objective 23-13 and its related sub-objectives measuring comprehensive laboratory services in support of essential public health programs, the Association of Public Health Laboratories (APHL) collaborated with the Centers for Disease Control and Prevention (CDC) to create and administer a survey of state public health laboratories (PHLs).
METHODS: A committee of APHL, with representation from CDC, constructed the survey based on the 11 Core ...
| Also Ranks for: Public Health | disease control | prevention united states | laboratory services | core functions |
BACKGROUND: Desmoplastic small round cell tumor (DSRCT) is a recently described neoplasm characterized by aggressive biology, occurrence in body cavities, expression of antigens from multiple cell lineages and a specific translocation between chromosomes 11 and 22. Most of the published information on this neoplasm is histologic. The case presented here enabled presentation of the cytomorphologic and immunocytochemical features of aspirated cytologic material obtained from this unique ...
| Also Ranks for: Cell Tumor | small round | needle carcinoma | diagnosis dsrct | xray computed |
A 47-yr-old man with history of metastatic low-grade rectal leiomyosarcoma presented with progressive protrusion of his left eye due to an enlarging orbital mass. The differential diagnosis included tumor metastasis or orbital infection due to an unknown infectious agent. Diagnostic fine-needle aspiration (FNA) of the orbit was performed on an urgent basis to institute proper therapy and to save the patient's eyesight. Cytomorphologic examination of the material demonstrated a ...
| Also Ranks for: Needle Diagnosis | orbital leiomyosarcoma | tumor metastasis | outcome humans | differential fatal |
Stanley L Inhorn: Influence Statistics
| Concept | World rank |
|---|---|
| nonspecific inhibitors sera | #1 |
| compatibility trypsin | #1 |
| kaolin procedure | #1 |
| dextrans erythrocytes hemagglutination | #1 |
| human cells sensitive | #1 |
| reported kaolin | #1 |
| serum treatment procedures | #1 |
| sensitive chicken cells | #1 |
| heparin manganous | #1 |
| erythrocytes hemagglutination trypsin | #1 |
| comparative tests cells | #1 |
| titers kaolin | #1 |
| provision laboratory services | #2 |
| aphl united states | #2 |
| compatibility comparative tests | #2 |
| general requirements types | #2 |
| satisfy clia | #2 |
| cell types reproducibility | #2 |
| 28 monitors | #2 |
| requirements clia | #2 |
| decade aphl | #2 |
| functions sphls | #2 |
| meet clia | #2 |
| plan cytology | #2 |
| sphls decade | #2 |
| clia law | #2 |
| laboratory services decade | #2 |
| thinlayer cervical cytology | #2 |
| sphls aphl | #2 |
| decade 2004 survey | #2 |
| document qa systems | #2 |
| healthy people sphls | #2 |
| died hepatocytes | #3 |
| serodiagnosis infectious mononucleosis | #3 |
| chromosome banding g2 | #3 |
| tetracycline dactinomycin | #3 |
| tcdd died | #3 |
| ld95 dose histopathology | #3 |
| human developmental mixoploidy | #3 |
| wasting syndrome lethality | #3 |
| tcddtreated rats responses | #3 |
| death tcddtreated rats | #3 |
| g2 tetracycline | #3 |
| erythrocytes rubella | #3 |
| healthy people support | #3 |
| thinprep papanicolaou test | #3 |
| ld25 dose tcdd | #3 |
| treatments giemsa | #3 |
| banding specificity | #3 |
| 11 core functions | #3 |
Key People For Public Health
Stanley L Inhorn:Expert Impact
Concepts for whichStanley L Inhornhas direct influence:Public health, Public health laboratories, Guinea pigs, Thyroid status, Laboratory services, Rubella hemagglutination, Human erythrocytes, Health laboratories.
Stanley L Inhorn:KOL impact
Concepts related to the work of other authors for whichfor which Stanley L Inhorn has influence:Cervical cancer, Trisomy 13, Human pair, Prenatal diagnosis, Situ hybridization, Publication abnormalities, Patau syndrome.
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