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    • Michel J Canis
    • Michel J Canis

      Michel J Canis

      Department of Gynecological Surgery, Clermont-Ferrand University Hospital Estaing, Clermont-Ferrand, France; EnCoV, IP, UMR 6602 CNRS, Université Clermont Auvergne, ...



      KOL Resume for Michel J Canis


      Department of Gynecological Surgery, Clermont-Ferrand University Hospital Estaing, Clermont-Ferrand, France; EnCoV, IP, UMR 6602 CNRS, Université Clermont Auvergne, Clermont-Ferrand, France.


      CHU Clermont-Ferrand, CHU Estaing, Pôle gynécologie obstétrique et reproduction humaine - Assistance médicale à la procréation - CECOS, Clermont-Ferrand, France.

      EnCoV, IP, UMR 6602 CNRS, université Clermont-Auvergne, Clermont-Ferrand, France


      Université Clermont Auvergne, Institut Pascal, UMR6602, CNRS/UCA/SIGMA, Clermont-Ferrand, France


      Department of Gynecological Surgery, CHU Clermont-Ferrand, 63000 Clermont-Ferrand, France;, (A.P.-M.);, (P.C.);, (A.-S.G.);, (A.C.);, (M.C.);, (N.B.)

      Faculty of Medecine, ISIT-University of Auvergne, Clermont-Ferrand, France

      CHU Clermont-Ferrand, Service de Chirurgie Gynécologique (Drs. Comptour, Chauvet, Grémeau, Pouly, Canis, and Bourdel).


      Service de gynécologie-obstétrique et reproduction humaine, CHU Estaing, 1, place Lucie-Aubrac, 63003 Clermont-Ferrand, France.

      Faculty of Medecine, ALCoV UMR6284, CNRS/Université d’Auvergne, ISIT, Clermont-Ferrand, France


      CICE (Centre International de Chirurgie Endoscopique), Faculty of Medicine, Clermont-Ferrand, France1

      CHU University Hospital Clermont‐Ferrand Gynecological Surgery Service Clermont‐Ferrand France


      Faculté de Médecine, ALCoV-ISIT (UMR6284 CNRS / Université d’Auvergne), 28 Place Henri Dunant, 63000, Clermont-Ferrand, France


      Department of Gynaecologic Surgery, Centre Hospitalier Universitaire Estaing, Clermont-Ferrand, France



      Michel J Canis: Influence Statistics

      Sample of concepts for which Michel J Canis is among the top experts in the world.
      Concept World rank
      redcap internet platform #1
      elastic endometrial #1
      persistent endometriomas #1
      35mm peritoneum #1
      laparoscopic treatment uterine #1
      ivf–embryo transfer cycles #1
      laparoscopic videos problem #1
      painisnotwell #1
      interval practice #1
      stroma extrauterine sites #1
      severity laparotomic myomectomy #1
      afs 85 scoring #1
      révolution devant #1
      afs classification #1
      dermoid cysts endometriosis #1
      questions complexes #1
      gynecologic endoscopic surgery #1
      maternité clermontferrand #1
      richter hernia case #1
      uterine surface myoma #1
      delay surgical diagnosis #1
      myomas uterine cavity #1
      bipolar coagulation plasmajet #1
      realtime long durations #1
      adhesion formation rules #1
      extrauterine endometrial tissue #1
      tubal involvement duration #1
      pathologist images #1
      endométriosiques #1
      lipogranulomatosis peritonitis #1
      rgroup pgroup #1
      difficulties learning curve #1
      patients adenomyoma #1
      uterus local conditions #1
      anesthesia groups pods #1
      afsr5 severe endometriosis #1
      local intravenous treatments #1
      healing adhesion #1
      cpi ees #1
      laparoscopic hysterectomy torsion #1
      opérées tôt #1
      entire nonmodified video #1
      adhesions cystic lesions1 #1
      severe consequences hydroureteronephrosis #1
      dissemination postoperative #1
      documentclass12ptminimal so3 #1
      midsecretory phase patients #1
      video surgical strategy #1
      191 pgy2 #1
      trauma initial event #1


      Prominent publications by Michel J Canis

      KOL-Index: 15301

      BACKGROUND: This study aimed to calculate costs and health-related quality of life of women with endometriosis-associated symptoms treated in referral centres.

      METHODS: A prospective, multi-centre, questionnaire-based survey measured costs and quality of life in ambulatory care and in 12 tertiary care centres in 10 countries. The study enrolled women with a diagnosis of endometriosis and with at least one centre-specific contact related to endometriosis-associated symptoms in 2008. The ...

      Known for Life Women | Endometriosis Study | Health Costs | Productivity Loss | Decreased Quality
      KOL-Index: 15009

      STUDY QUESTION: To what extent do the management of endometriosis and the symptoms that remain after treatment affect the quality of life in women with the disease?

      SUMMARY ANSWER: Many women with endometriosis had impaired quality of life and continued to suffer from endometriosis-associated symptoms even though their endometriosis has been managed in tertiary care centres.

      WHAT IS KNOWN ALREADY: The existing literature indicates that quality of life and work productivity is reduced in ...

      Known for Life Women | Sectional Survey | Endometriosis Study | Chronic Pain | Reproductive Medicine
      KOL-Index: 11831

      BACKGROUND: Ovarian response during IVF cycles after laparoscopic ovarian cystectomy for endometriotic cysts >3 cm is controversial. A retrospective study was designed to study this problem.

      METHODS: At laparoscopy, endometriomas >3 cm were treated by ovarian cystectomy, whilst adhesions and peritoneal endometriosis were treated using conventional techniques. Ovarian stimulation was achieved with clomiphene and gonadotrophins or with gonadotrophins after a desensitization with ...

      Known for Ovarian Response | Endometriotic Cysts | Embryo Transfer | Patients Endometriosis | Female Infertility
      KOL-Index: 11830

      BACKGROUND: The aim of this study was to investigate HOXA-10 expression in endometrium from infertile patients with different forms of endometriosis; with uterine fibromas, or with unexplained infertility and from normal fertile women.

      METHODS: Expression levels of HOXA-10 mRNA and protein in endometrium were measured during the mid-secretory phase. This study utilized laser capture microdissection, real-time RT-PCR and immunohistochemistry.

      RESULTS: HOXA-10 mRNA and protein expression ...

      Known for Infertile Patients | Unexplained Infertility | Uterine Fibromas | Hoxa10 Expression | Secretory Endometrium
      KOL-Index: 11374

      OBJECTIVE: To investigate differentially expressed genes in epithelial and stromal cells of eutopic endometrium from patients with deep endometriosis and women with normal pelvic cavities using laser capture microdissection and complementary DNA microarrays.

      DESIGN: Prospective study.

      SETTING: University hospital.

      PATIENT(S): Patients with deep endometriosis and fertile women who underwent laparoscopic tubal ligation or reversal of tubal sterilization.

      INTERVENTION(S): Endometrial tissue ...

      Known for Eutopic Endometrium | Deep Endometriosis | Gene Expression | Microarray Analysis | Laser Capture Microdissection
      KOL-Index: 11331

      BACKGROUND: Numerous studies concerning endometriosis and pain have been reported. However, there is no consensus on the best method to evaluate pain in endometriosis and many scales have been used. Moreover, there are only a few descriptions of minimal clinically important differences after treatment (MCID) to evaluate variations in pain. In our study, we aim to identify pain scales used in endometriosis pain treatment, to address their strong and weak points and to define which would ...

      Known for Endometriosis Pain | Scale Nrs | Quality Life | Dysmenorrhea Dyspareunia | Measurement Pelvic
      KOL-Index: 10911

      CONTEXT: Only a few, small, human studies on E-cadherin and beta-catenin expression in normal cycling human endometrium have been reported. It remains unclear whether expression of these molecules might be altered in the endometrium of infertile patients with endometriosis.

      OBJECTIVES: The aim of the present study was to investigate E-cadherin and beta-catenin expression in the endometrium of infertile patients with endometriosis, those with uterine fibromas, and patients with ...

      Known for Protein Expression | Infertile Patients | Epithelial Cells | Beta Catenin | Secretory Endometrium
      KOL-Index: 10202

      Endometriosis, a common gynecological disorder that causes infertility and pelvic pain, is defined as the presence of endometrial glands and stroma within extra-uterine sites. However, despite extensive studies its etiology and pathogenesis are not completely understood. Differentially expressed genes were investigated in epithelial and stromal cells from deep endometriosis and matched eutopic endometrium using cDNA microarrays and laser capture microdissection. Validation of results of ...

      Known for Deep Endometriosis | Gene Expression | Laser Capture Microdissection | Dna Microarray Analysis | Receptor Mor
      KOL-Index: 10050

      STUDY QUESTION: Can deep infiltrating endometriotic stromal cells (DES) sense changes in extracellular matrix (ECM) stiffness and respond to them?

      SUMMARY ANSWER: Soft matrices inhibit cell proliferation and inactivate the fibrotic phenotype of DES in vitro.

      WHAT IS KNOWN ALREADY: Deep infiltrating endometriosis (DIE) is characterized histologically by dense fibrous tissue. Tissue stiffening is a hallmark of fibrosis. Studies show that matrix stiffness is involved in the progression of ...

      Known for Cell Proliferation | Fibrotic Phenotype | Endometriotic Stromal | Matrix Stiffness | 30 Kpa
      KOL-Index: 9697

      OBJECTIVES: Endometriosis and quality of life has been the subject of much research, however, there is little consensus on how best to evaluate quality of life in endometriosis, resulting in many and diverse scales being used. In our study, we aim to identify quality of life scales used in endometriosis, to review their strengths and weaknesses and to establish what would define an ideal scale in the evaluation of endometriosis-related quality of life.

      MATERIALS AND METHODS: A search of ...

      Known for Quality Life | Patients Endometriosis | Surveys Questionnaires | Female Health | Selected Analysis
      KOL-Index: 9666

      OBJECTIVE: To quantify the expression of transforming growth factor beta1 in nerve fibers in endometriotic lesions and to correlate it with dysmenorrhea and appearance of endometriotic implants.

      DESIGN: Prospective comparative study.

      SETTING: University hospital.

      PATIENT(S): Peritoneal endometriotic specimens obtained from 35 patients diagnosed with endometriosis were compared with biopsies of normal peritoneum from 10 patients without endometriosis.

      INTERVENTION(S): ...

      Known for Nerve Fibers | Growth Factor | Endometriotic Implants | Normal Peritoneum | Patients Endometriosis
      KOL-Index: 9625

      OBJECTIVE: To quantify and compare messenger RNA (mRNA) levels of ER-alpha and ER-beta among ovarian endometriotic cysts and red and black peritoneal endometriotic lesions.

      DESIGN: Prospective study.

      SETTING: University hospital.

      PATIENT(S): Patients with or without endometriosis.

      INTERVENTION(S): Samples of peritoneal (n = 33) and ovarian endometriotic lesions (n = 37) were obtained during laparoscopic surgery. Normal eutopic endometrial tissues and macroscopically normal peritoneal ...

      Known for Estrogen Receptor | Endometriotic Tissues | Beta Alpha | Peritoneal Lesions | Ovarian Endometriosis
      KOL-Index: 9498

      BACKGROUND: The aim of this study was to identify risk factors for the removal of normal ovarian tissue during laparoscopic cystectomy for endometriosis.

      METHODS: A total of 121 patients who had histologically confirmed ovarian endometriosis and 56 control patients who had other histologically confirmed benign cysts were included for the present analysis. The blocks of removed tissue were sectioned at 120 microm intervals and a total of five sections were analyzed for each ovarian cyst. ...

      Known for Ovarian Endometriosis | Laparoscopic Cystectomy | Preoperative Medical Treatment | Cyst Wall | Previous Surgery
      KOL-Index: 9259

      OBJECTIVE: To investigate mRNA expression of aromatase and 17beta-hydroxysteroid dehydrogenase type 2 (17betaHSD2) in epithelial and stromal cells from eutopic and ectopic endometrium of patients with deep endometriosis.

      DESIGN: Prospective study.

      SETTING: University hospital.

      PATIENT(S): Patients with deep endometriosis and fertile women with macroscopically normal pelvic cavities.

      INTERVENTION(S): During surgery, 30 endometrial and 16 endometriotic samples were obtained from 30 ...

      Known for Eutopic Endometrium | Capture Microdissection | Stromal Cells | Endometriosis Patients | Type 2
      KOL-Index: 8954

      OBJECTIVE: to evaluate the complications after surgery for deep endometriosis.

      DESIGN: retrospective study.

      SETTING: data from the CHU Estaing database and patients' charts between January 1987 and December 2007.

      SAMPLE: all women given surgical treatment for deep endometriosis.

      METHODS: women who underwent surgery for deep endometriosis were reviewed for intra- and postoperative complications.

      MAIN OUTCOME MEASURES: primary outcomes were rates of intra- and postoperative complications. ...

      Known for Deep Endometriosis | Complications Surgery | Segmental Resection | Surgical Treatment | Rectal Diseases

      Key People For Laparoscopic Treatment

      Top KOLs in the world
      Michel J Canis
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      Jean Luc Pouly
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      Gérard Mage
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      Arnaud Wattiez
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      Camran R Nezhat
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      Michel J Canis:Expert Impact

      Concepts for whichMichel J Canishas direct influence:Laparoscopic treatment,  Laparoscopic surgery,  Laparoscopic management,  Laparoscopic hysterectomy,  10 steps,  Deep endometriosis,  Co2 pneumoperitoneum,  Ectopic pregnancy.

      Michel J Canis:KOL impact

      Concepts related to the work of other authors for whichfor which Michel J Canis has influence:Ectopic pregnancy,  Laparoscopic surgery,  Women endometriosis,  Ovarian cancer,  Pelvic pain,  Eutopic endometrium,  Surgical treatment.



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      Department of Gynecological Surgery, Clermont-Ferrand University Hospital Estaing, Clermont-Ferrand, France; EnCoV, IP, UMR 6602 CNRS, Université Clermont Auvergne, Clermont-Ferrand, France. | Department of Obstetrics Gynecology and Reproductive Medi

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