Christian Candrian

Christian Candrian

Ospedale Regionale Di Lugano Civico E Italiano, Lugano, Ticino, Switzerland

Direct Impact

Concepts for which Christian Candrian has direct influence:

bone bruise
knee osteoarthritis
pain sensitization
prp injections
articular chondrocytes
platelet-rich plasma
patellar tendinopathy

External impact

Concepts related to the work of other authors for which Christian Candrian has influence:

osteochondritis dissecans
knee arthroscopy
huvec cells
hypertonic dextrose
late presenters
giant reed
magnetic resonance imaging

Prominent publications by Christian Candrian

KOL-Index: 73 Ionizing radiation (IR) is used in radiotherapy as a treatment to destroy cancer. Such treatment also affects other tissues, resulting in the so-called normal tissue complications. Endothelial cells (ECs) composing the microvasculature have essential roles in the microenvironment's homeostasis (ME). Thus, detrimental effects induced by irradiation on ECs can influence both the tumor and ...
Known for
Tissue Vitro | Models Microvascular | Production Irradiation | Highlighted Critical
KOL-Index: 71 OBJECTIVE: The purpose of this manuscript is to analyze the evidence regarding etiopathogenesis of knee osteochondritis dissecans (OCD) lesions through a systematic review, so to summate the current understanding of the origin and progression of this pathologic articular processes. DESIGN: A systematic review of the literature was performed on the PubMed and Cochrane databases on October ...
KOL-Index: 60 PurposeTo quantify union rate, complication rate, reintervention rate, as well as functional outcome after vascularized fibular bone grafts (VFGs) for the treatment of long-bone defects.MethodsA comprehensive search was performed in the PubMed, Web of Science, and Cochrane databases up to August 18, 2020. Randomized controlled trials, comparative studies, and case series describing the ...
Known for
Purposeto Quantify Union Rate | Complex Demanding Technique | Documented Union | “checklist
KOL-Index: 48 OBJECTIVE: Inflammation plays a central role in the pathophysiology of rheumatic diseases as well as in osteoarthritis. Temperature, which can be quantified using infrared thermography, provides information about the inflammatory component of joint diseases. This systematic review aims at assessing infrared thermography potential and limitations in these pathologies. DESIGN: A systematic ...
Known for
Thermography Diagnosis | Rheumatic Correlation | Monitoring Response | Temperature Osteoarthritis
KOL-Index: 44 BACKGROUND: There is no consensus about the safety of outpatient total hip arthroplasty (THA). Therefore, the purpose of this meta-analysis was to quantitatively evaluate and compare outpatient and inpatient THA studies in terms of complication and readmission rates. METHODS: A systematic search of the literature was performed on 26 July 2019 on PubMed, Web of Science, Cochrane library, and ...
Known for
Future High-Level | Complications Readmissions | Rate Outpatient | Prisma Guidelines
KOL-Index: 43 PurposeTo evaluate the evidence supporting safety and effectiveness of intra-articular injective treatments for ankle lesions ranging from osteochondral lesions of the talus (OLT) to osteoarthritis (OA).MethodsA systematic review and a meta-analysis were performed on PubMed, Embase, and Cochrane Library in March 2020. Safety was evaluated through the reported side effects and effectiveness ...
Known for
Osteoarthritis Meta | Supports Safety | Injective | Reported Olt
KOL-Index: 42 Muscle fibrosis represents the end stage consequence of different diseases, among which muscular dystrophies, leading to severe impairment of muscle functions. Muscle fibrosis involves the production of several growth factors, cytokines and proteolytic enzymes and is strictly associated to inflammatory processes. Moreover, fibrosis causes profound changes in tissue properties, including ...
Known for
Candidate Anti-Fibrotic Agents | Proteolytic Enzymes | Harsh Conditions | Bench
KOL-Index: 39 The prevalence of arthritic diseases is increasing in developed countries, but effective treatments are currently lacking. The injection of mesenchymal stem cells (MSCs) represents a promising approach to counteract the degenerative and inflammatory environment characterizing those pathologies, such as osteoarthritis (OA). However, the majority of clinical approaches based on MSCs are used ...
Known for
Mscs Secretome | Degenerative Inflammatory Environment | Innovative Therapeutic Approaches | Arthritic Increasing
KOL-Index: 39 Background: Both nonoperative and operative treatments have been proposed to manage distal biceps brachii tendon avulsions. However, the advantages and disadvantages of these approaches have not been properly quantified. Purpose: To summarize the current literature on both nonoperative and operative approaches for distal biceps brachii tendon ruptures and to quantify results and limitations. ...
Known for
Supination Pronation | Nonoperative Operative Approaches | Methods Literature | Approach Meta
KOL-Index: 38 BACKGROUND: Pain sensitization, defined as an increased responsiveness of nociceptive neurons to normal input, is detected in several musculoskeletal diseases, but there are no systematic reviews or meta-analyses about pain sensitization in shoulder pain. OBJECTIVES: The aim of the study was to document pain sensitization rate and its impact in patients with shoulder pain. MATERIALS AND ...
Known for
Pressure Pain | 29 77 | Level I-Iv | Musculoskeletal Shoulder Disorders

Ospedale Regionale di Lugano Civico e Italiano, Lugano, Ticino, Switzerland

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