• Disease
  • Lung
  • Lung Cancer
  • Wu‐huei Hsu

    Prominent publications by Wu‐Huei Hsu

    KOL Index score: 14305

    Color Doppler ultrasound (US) was performed in 153 patients (including 102 with lung cancer and 51 with benign lesions) to assess pulsatile flow signals in thoracic lesions. The values of resistive index (RI) and pulsatility index (PI) of color Doppler US pulsatile flow signals in lung cancers and benign lesions were measured, analyzed, and compared. In the enrolled 153 patients with thoracic lesions, 61 lung cancers and 34 benign lesions had detectable color Doppler US pulsatile flow ...

    Also Ranks for: Benign Lesions |  color doppler |  lung cancers |  pulsatile flow |  signals thoracic
    KOL Index score: 12153

    The aim of this study was to determine whether pleural fluid C-reactive protein (CRP) is useful in distinguishing complicated parapneumonic pleural effusion (CPPE) and empyema from uncomplicated parapneumonic pleural effusions (UPPE). A total of 69 consecutive patients with parapneumonic effusions were enrolled in the study: 29 with UPPE, 29 with CPPE, and 11 with empyema. Concentrations of standard biochemical parameters together with CRP in the pleural fluid were measured using an ...

    Also Ranks for: Pleural Fluid |  reactive protein |  sensitivity specificity |  cppe uppe |  complicated parapneumonic
    KOL Index score: 11595

    Sixty-eight patients with thoracic lesions (48 with lung cancer and 20 with benign lesions) underwent color Doppler ultrasound (US) examinations. Of those, 21 patients (13 with lung cancer and eight with benign lesions) also received resections, and the correlation between color Doppler US signals and resected histologic specimens was evaluated. Our results showed that three patterns of color Doppler US signals could be detected and confirmed: pulsatile flow (artery), constant flow, and ...

    Also Ranks for: Color Doppler |  thoracic lesions |  lung cancer |  pulsatile flow |  48 patients
    KOL Index score: 11441

    OBJECTIVES: Patients with asthma-chronic obstructive pulmonary disease (COPD) overlap syndrome (ACOS) and cardiovascular diseases (CVDs) share common risk factors. However, the association between ACOS and the incidence of CVDs has not been reported. This study investigated the relationship between CVDs and ACOS in the general population.

    SETTING: Data were obtained from Taiwan's National Health Insurance Research Database for the period 2000 to 2010.

    PARTICIPANTS: The ACOS cohort ...

    Also Ranks for: Heart Failure |  pulmonary disease |  chronic obstructive |  asthma copd |  acos cohort
    KOL Index score: 11427

    BACKGROUND: There are several publications reported that obstructive sleep apnea (OSA) was associated with asthma. However, large-scaled, population-based cohort study has been limited. We aimed to examine the risk of OSA among adult patients with asthma in an Asian population.

    METHODS: We conducted a retrospective cohort study using data from the National Health Insurance (NHI) of Taiwan. The asthma cohort included 38,840 newly diagnosed patients between 2000 and 2010. The date of ...

    Also Ranks for: Sleep Apnea |  osa asthma |  comparison cohort |  age year |  taiwan adult
    KOL Index score: 10752

    BACKGROUND: Studies investigating the epidemiological relationship between scrub typhus and the subsequent development of acute coronary syndrome (ACS) are lacking. Therefore, we conducted a nationwide longitudinal cohort study in Taiwan to explore whether patients with scrub typhus are at an increased risk of developing ACS.

    METHODS: This study investigated the incidence and risk factors for ACS in 5215 patients newly diagnosed with scrub typhus from the Taiwan National Health Insurance ...

    Also Ranks for: Scrub Typhus |  acute coronary syndrome |  nationwide cohort study |  acs patients |  sex age
    KOL Index score: 10586

    INTRODUCTION: Given one third of the human population have been infected with tuberculosis, it is important to delineate the relationship between tuberculosis and lung cancer. This study explored whether contracting pulmonary tuberculosis is associated with an increased risk of developing lung cancers.

    METHODS: In a cohort of 716,872 insured subjects, free from cancers, aged 20 years and older, 4480 patients with newly diagnosed tuberculosis were identified from the universal insurance ...

    Also Ranks for: Lung Cancer |  pulmonary tuberculosis |  hazard ratio |  population cohort study |  copd 95
    KOL Index score: 10586

    Bufalin is a key component of a Chinese medicine (Chan Su) and has been proved effective in killing various cancer cells. Its role in inducing DNA damage and the inhibition of the DNA damage response (DDR) has been reported, but none have studied such action in lung cancer in detail. In this study, we demonstrated bufalin-induced DNA damage and condensation in NCI-H460 cells through a comet assay and DAPI staining, respectively. Western blotting indicated that bufalin suppressed the ...

    Also Ranks for: Dna Damage |  cancer cells |  cell death |  protein bufalin |  human lung
    KOL Index score: 10445

    Several studies have shown that gallic acid (GA) induces apoptosis in different cancer cell lines, whereas the mechanism of action of GA-induced apoptosis at the molecular level in human non-small-cell lung cancer NCI-H460 cells is not well-known. Here, GA decreasing the percentage of viable NCI-H460 cells was investigated; GA-induced apoptosis involved G2/M phase arrest and intracellular Ca(2+) production, the loss of mitochondrial membrane potential (DeltaPsi(m)), and caspase-3 ...

    Also Ranks for: Tumor Growth |  gallic acid |  induces apoptosis |  cell lung |  protein levels
    KOL Index score: 10416

    OBJECTIVE: Studies investigating the relationship between sleep disorders (SDs) and the risk of venous thromboembolism (VTE) are scarce. The present study from Taiwan evaluated whether the risk of VTE was associated with SDs other than sleep apnea.

    METHODS: The present study investigated the incidence and risk of VTE in 46,371 people with SDs, compared with 92,742 controls without SDs. The follow-up period began from the date of entering the study cohort to the date of a VTE event, ...

    Also Ranks for: Sleep Disorders |  venous thromboembolism |  risk vte |  based cohort |  sds aged
    KOL Index score: 10031

    BACKGROUND/PURPOSE: Lung cancer screening using low-dose computed tomography (CT) has been reported to reduce lung cancer-specific mortality for smokers at high risk. However, despite different characteristics of lung cancer in Asia, there are few data concerning this specific population for screening. We aim to analyze the performance of lung cancer screening with low-dose CT concurrent with chest radiography in Taiwan, with reference to international experience.

    METHODS: During the ...

    Also Ranks for: Lung Cancer Screening |  computed tomography |  tertiary hospital |  early detection |  cancer female humans
    KOL Index score: 9813

    BACKGROUND: Previous studies have suggested that chronic obstructive pulmonary disease (COPD) is an independent risk factor for lung cancer. There are some evidence that people with diabetes are at a risk of developing many forms of cancer, but inconclusive with regard to lung cancer. The aim of this study was to evaluate whether COPD with or without type 2 diabetes mellitus (T2DM) influences the risk of developing lung cancer.

    METHODS: This is a retrospective cohort study consisting of ...

    Also Ranks for: Lung Cancer |  patients copd |  chronic obstructive |  pulmonary disease |  retrospective cohort study
    KOL Index score: 9798

    BACKGROUND: There is a demonstrated association between asthma and irritable bowel syndrome (IBS). In this study, we examined the bidirectional association between asthma and IBS using a nationwide database.

    METHODS: We conducted two retrospective cohort studies using data obtained from the National Health Insurance of Taiwan. Study 1 included 29,648 asthma patients newly diagnosed between 2000 and 2010. Study 2 included 29,875 IBS patient newly diagnosed between 2000 and 2010. For each ...

    Also Ranks for: Irritable Bowel Syndrome |  asthma ibs |  comparison cohort |  retrospective studies |  proportional hazards
    KOL Index score: 9578

    BACKGROUND: Rapid on-site evaluation (ROSE) of cytologic specimens is a useful ancillary technique in needle aspiration procedures of pulmonary/mediastinal lesions, but few reports had been carried out to confirm the utility in the diagnosis of peripheral pulmonary lesions (PPLs) by radial probe endobronchial ultrasound (R-EBUS).

    METHODS: To evaluate the impact of ROSE on the diagnostic yield of R-EBUS for PPLs, we retrospectively analyzed the diagnostic yields of transbronchial biopsy ...

    Also Ranks for: Diagnostic Yield |  peripheral pulmonary lesions |  rebus ppls |  endobronchial ultrasound |  tbb rose
    KOL Index score: 9540

    The aim of this study was to investigate the expression of P-glycoprotein (Pgp), multidrug resistance-related protein-1 (MRP1), and lung resistance-related protein (LRP) in response to chemotherapy in untreated small cell lung cancer (SCLC). Immunohistochemical analyses were performed on multiple nonconsecutive sections of biopsy specimens to detect Pgp, MRP1, and LRP expression in 40 patients with SCLC before chemotherapeutic induction. Response to chemotherapy was evaluated by clinical ...

    Also Ranks for: Multidrug Resistance |  cell lung |  chemotherapy response |  patients sclc |  pgp mrp1


    Wu‐Huei Hsu: Influence Statistics

    Sample of concepts for which Wu‐Huei Hsu is among the top experts in the world.
    Concept World rank
    ssp infectious #1
    ≤5 years sex #1
    frequent 112 #1
    pleural effusions empyemas #1
    vessel signals blooming #1
    dfus influence #1
    hemothoraces 03 #1
    efficacy pigtail #1
    pleural female #1
    pdus cdus #1
    empyema difference #1
    suspected tract metastasis #1
    empyemas #1
    haprelated empyema #1
    incident respiratory failure #1
    ssp university #1
    pigtail catheter drainage #1
    pigtail catheter treatment #1
    lesions dfus #1
    empyemic patients micu #1
    signals blooming #1
    tuberculosis subsequent #1
    nonspecific cell type #1
    complex nonseptated #1
    effusion cultures #1
    differential empyema #1
    cnb amms #1
    sex preexisting comorbidities #1
    dfus color doppler #1
    tubes drainage #1
    fnab pneumothorax #1
    chest medicine #1
    complex septated #1
    phase 201tl #1
    subclassification fine #1
    cdus chest medicine #1
    needle hemoptysis #1
    hemoptysis 1 #1
    38 drains #1
    nonsle cohort subjects #1
    cdus thoracic #1
    tubes pigtail #1
    332 pigtail catheters #1

    Key People For Lung Cancer

    Top KOLs in the world
    Ahmedin M Jemal
    united states breast cancer addis ababa
    Rebecca L Siegel
    united states colorectal cancer incidence rates
    Freddie Ian Bray
    cancer incidence nordic countries mortality rates
    Jacques Ferlay
    cancer incidence global burden latin america
    Adi F Gazdar
    lung cancer cell lines aberrant methylation
    Frances Alice Shepherd
    lung cancer small cell adjuvant chemotherapy

    Wu‐Huei Hsu:Expert Impact

    Concepts for whichWu‐Huei Hsuhas direct influence:Lung cancer,  Benign lesions,  Color doppler,  Dna damage,  Lung cancers,  Thoracic lesions,  Chemotherapy response,  Periodontal diseases.

    Wu‐Huei Hsu:KOL impact

    Concepts related to the work of other authors for whichfor which Wu‐Huei Hsu has influence:Lung cancer,  Gallic acid,  Pleural effusion,  Pulmonary tuberculosis,  Rheumatoid arthritis,  Sleep apnea,  Chronic obstructive.



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    Graduate Institute of Biomedical Sciences and School of Medicine, China Medical University, Taichung, Taiwan | Graduate Institute of Biomedical Sciences and School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan | Graduat