KOL | David Peter StrachanPopulation Health Research Institute, St George’s, University of London, Cranmer Terrace, London, SW17 0RE, UK | Full professor. | Population Health Research Institute, St ... |
KOL Resume for David Peter Strachan
| Year | |
|---|---|
| 2022 | Population Health Research Institute, St George’s, University of London, Cranmer Terrace, London, SW17 0RE, UK Full professor. |
| 2021 | Population Health Research Institute, St George’s University of London, Cranmer Terrace, SW17 0RE London, United Kingdom |
| 2020 | Population Health Research Institute, St George's, University of London, London, United Kingdom Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK Institute of Clinical Medicine, University of Oslo, P.O. 1171 Blindern, 0318 Oslo, Norway |
| 2019 | Population Health Research Institute, St. George’s University of London, London, UK |
| 2018 | Population Health Research Institute, St George, ’, s, University of London, London SW17 0RE, UK |
| 2017 | Population Health Research Institute, St. George's, University of London, London, SW17 0RE, United Kingdom |
| 2016 | Population Health Research Institute, St. George’s, University of London, London SW17 0RE, United Kingdom Division of Community Health Sciences, St George's University of London, London SW17 0RE, UK |
| 2015 | Population Health Research Institute, St George's, University of London, Cranmer Terrace, London WC1B 5DN, UK St. George's, University of London, London, U.K. Institute of Public Health Sciences, St George's University of London, London, United Kingdom |
| 2014 | St George's University of London Division of Population Health Sciences and Education London UK For the authors' affiliations see the Acknowledgements section. |
| 2013 | Division of Population Health Sciences and Education, St. George's, University of London, London, UK |
| 2012 | MRC-HPA Centre for Environment and Health, St Georges, University of London, United Kingdom Department of Medical Informatics, Erasmus Medical Center, Rotterdam, The Netherlands Population Health Sciences and Education, St George's, University of London |
| 2011 | Division of Population Health Sciences and Education, St George’s University of London, London, United Kingdom Community Health Sciences, St George's University of London, Cranmer Terrace, London, SW17 ORE, UK |
David Peter Strachan: Influence Statistics
| Concept | World rank |
|---|---|
| diagnosis gprd | #1 |
| iga antibody titre | #1 |
| pollen counts england | #1 |
| consistent associations exposure | #1 |
| variation outcome prevalence | #1 |
| childhood prevalence asthma | #1 |
| rubella vaccine allergic | #1 |
| examination england | #1 |
| 95 airway responsiveness | #1 |
| healthy british adults | #1 |
| susceptibility loci kif21b | #1 |
| adultonset asthma interaction | #1 |
| infection geohelminth parasites | #1 |
| 95 mumol | #1 |
| sunlight gabriel | #1 |
| alspac trpa1 | #1 |
| secondary pneumothorax england | #1 |
| role social differences | #1 |
| worldwide time | #1 |
| minor alleles stx2 | #1 |
| menarche asthma | #1 |
| adjustment frequent wheeze | #1 |
| cal clh | #1 |
| socioeconomic status region | #1 |
| adjustment consultation frequency | #1 |
| child comorbidity crp | #1 |
| plants rhinitis | #1 |
| pefr addition | #1 |
| data sunlight | #1 |
| day interactionex | #1 |
| pefr area | #1 |
| adjustment centrelevel variation | #1 |
| england thunderstorms | #1 |
| minor deviations deviations | #1 |
| loci grass sensitization | #1 |
| eczema migraine | #1 |
| wheeze diagnosed asthma | #1 |
| fev1 spirometric indices | #1 |
| development vaccine immunity | #1 |
| duration neuroendocrine factors | #1 |
| multilevel regression variation | #1 |
| bcg vaccination year | #1 |
| circulatory diseases hseshs | #1 |
| impedance tympanometry | #1 |
| individual level analyses | #1 |
| migraine asthma | #1 |
| relation passive smoking | #1 |
| phlegm symptoms | #1 |
| wheezing elevated ige | #1 |
| b58c | #1 |
Open the FULL List in Excel | |
Prominent publications by David Peter Strachan
BACKGROUND: Understanding the genetic basis of airflow obstruction and smoking behaviour is key to determining the pathophysiology of chronic obstructive pulmonary disease (COPD). We used UK Biobank data to study the genetic causes of smoking behaviour and lung health.
METHODS: We sampled individuals of European ancestry from UK Biobank, from the middle and extremes of the forced expiratory volume in 1 s (FEV1) distribution among heavy smokers (mean 35 pack-years) and never smokers. We ...
| Known for Uk Biobank | Lung Function | Genetic Association | Smoking Behaviour | Chronic Obstructive |
BACKGROUND: As part of the International Study of Asthma and Allergies in Childhood (ISAAC), prevalence surveys were conducted among representative samples of school children from locations in Europe, Asia, Africa, Australia, North and South America.
SUBJECTS: 257,800 children aged 6-7 years from 91 centres in 38 countries, and 463,801 children aged 13-14 years from 155 centres in 56 countries.
METHODS: Written symptom questionnaires were translated from English into the local language ...
| Known for Allergic Rhinoconjunctivitis | International Study | Prevalence Rhinitis | Worldwide Variations | Asthma Allergies |
Incidence and prognosis of asthma and wheezing illness from early childhood to age 33 in a national British cohort
[ PUBLICATION ]
OBJECTIVE: To describe the incidence and prognosis of wheezing illness from birth to age 33 and the relation of incidence to perinatal, medical, social, environmental, and lifestyle factors.
DESIGN: Prospective longitudinal study.
SETTING: England, Scotland and Wales.
SUBJECTS: 18,559 people born on 3-9 March 1958. 5801 (31%) contributed information at ages 7, 11, 16, 23, and 33 years. Attrition bias was evaluated using information on 14, 571 (79%) subjects.
MAIN OUTCOME MEASURE: History ...
| Known for Wheezing Illness | Early Childhood | Incidence Age | Prognosis Asthma | Fever Eczema |
OBJECTIVE: To investigate variations in the prevalence of self reported symptoms, diagnosis, and treatment of asthma in 12-14 year old children.
DESIGN: Self completion questionnaire.
SETTING: Great Britain.
SUBJECTS: All pupils aged 12-14 years in a stratified cluster sample of 93 large mixed secondary schools in 1995.
MAIN OUTCOME MEASURES: Self reported prevalence of symptoms, diagnosis, and treatment of asthma at four geographical levels.
RESULTS: 27,507 questionnaires were completed ...
| Known for Asthma Symptoms | Great Britain | International Study | Prevalence Diagnosis | 14 Year |
BACKGROUND: A study was undertaken to investigate the relationship between daily hospital admissions for asthma and air pollution in London in 1987-92 and the possible confounding and modifying effects of airborne pollen.
METHODS: For all ages together and the age groups 0-14, 15-64 and 65+ years, Poisson regression was used to estimate the relative risk of daily asthma admissions associated with changes in ozone, sulphur dioxide, nitrogen dioxide and particles (black smoke), controlling ...
| Known for Air Pollution | Daily Admissions | Nitrogen Dioxide | Asthma London | Black Smoke |
BACKGROUND: Data for trends in prevalence of asthma, allergic rhinoconjunctivitis, and eczema over time are scarce. We repeated the International Study of Asthma and Allergies in Childhood (ISAAC) at least 5 years after Phase One, to examine changes in the prevalence of symptoms of these disorders.
METHODS: For the ISAAC Phase Three study, between 2002 and 2003, we did a cross-sectional questionnaire survey of 193,404 children aged 6-7 years from 66 centres in 37 countries, and 304,679 ...
| Known for Isaac Phase | Prevalence Symptoms | Sectional Surveys | Allergic Rhinoconjunctivitis | Time Trends |
BACKGROUND: Associations between traffic pollution on the street of residence and a range of respiratory and allergic outcomes in children have been reported in developed countries, but little is known about such associations in developing countries.
METHODS: The third phase of the International Study of Asthma and Allergies in Childhood (ISAAC) was carried out in 13- to 14-year-old and 6- to 7-year-old children across the world. A question about frequency of truck traffic on the street ...
| Known for Truck Traffic | Isaac Phase | Symptoms Asthma | Questionnaires Vehicle Emissions | Rhinoconjunctivitis Eczema |
Phase II of the International Study of Asthma and Allergies in Childhood (ISAAC II): rationale and methods
[ PUBLICATION ]
International comparative studies, investigating whether disease incidence or prevalence rates differ between populations and, if so, which factors explain the observed differences, have made important contributions to the understanding of disease aetiology in many areas. In Phase I of the International Study of Asthma and Allergies in Childhood (ISAAC), the prevalence rates of symptoms of asthma, allergic rhinitis and atopic eczema in 13-14-yr-olds, assessed by standardised ...
| Known for International Study | Asthma Allergies | Prevalence Rates | Atopic Eczema | Childhood Isaac |
Association of Helicobacter pylori and Chlamydia pneumoniae infections with coronary heart disease and cardiovascular risk factors
[ PUBLICATION ]
OBJECTIVE: To investigate the relation between seropositivity to chronic infections with Helicobacter pylori and Chlamydia pneumoniae and both coronary heart disease and cardiovascular risk factors.
DESIGN: Cross sectional study of a population based random sample of men. Coronary heart disease was assessed by electrocardiography, Rose angina questionnaire, and a history of myocardial infarction; serum antibody levels to H pylori and C pneumoniae were measured, risk factor levels ...
| Known for Cardiovascular Risk Factors | Coronary Heart Disease | Helicobacter Pylori | Pneumoniae Infections | Outcome Measures |
Associations of wheezing phenotypes in the first 6 years of life with atopy, lung function and airway responsiveness in mid-childhood
[ PUBLICATION ]
BACKGROUND: Patterns of wheezing during early childhood may indicate differences in aetiology and prognosis of respiratory illnesses. Improved characterisation of wheezing phenotypes could lead to the identification of environmental influences on the development of asthma and airway diseases in predisposed individuals.
METHODS: Data collected on wheezing at seven time points from birth to 7 years from 6265 children in a longitudinal birth cohort (the ALSPAC study) were analysed. Latent ...
| Known for Airway Responsiveness | Wheezing Phenotypes | 6 Years | Lung Function | Early Childhood |
Prenatal paracetamol exposure and risk of asthma and elevated immunoglobulin E in childhood
[ PUBLICATION ]
BACKGROUND: We recently found that paracetamol (acetaminophen) use in late pregnancy was associated with an increased risk of early wheezing in the offspring.
OBJECTIVE: To see whether use of paracetamol in late pregnancy is associated with an increased risk of asthma, wheezing and other atopic outcomes in the child at school age.
METHODS: In the population-based Avon Longitudinal Study of Parents and Children, we measured associations of paracetamol and aspirin use in late pregnancy ...
| Known for Paracetamol Exposure | Late Pregnancy | Asthma Wheezing | School Age | Children Mothers |
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study
[ PUBLICATION ]
Genome-wide association studies (GWAS) have identified more than 100 genetic variants contributing to BMI, a measure of body size, or waist-to-hip ratio (adjusted for BMI, WHRadjBMI), a measure of body shape. Body size and shape change as people grow older and these changes differ substantially between men and women. To systematically screen for age- and/or sex-specific effects of genetic variants on BMI and WHRadjBMI, we performed meta-analyses of 114 studies (up to 320,485 individuals ...
| Known for Bmi Whradjbmi | Body Size | Genetic Associations | Sex Age | Interaction Study |
Genetic loci for body mass index (BMI) in adolescence and young adulthood, a period of high risk for weight gain, are understudied, yet may yield important insight into the etiology of obesity and early intervention. To identify novel genetic loci and examine the influence of known loci on BMI during this critical time period in late adolescence and early adulthood, we performed a two-stage meta-analysis using 14 genome-wide association studies in populations of European ancestry with ...
| Known for Genetic Loci | Bmi Young Adult | Weight Gain | European Ancestry | Tnni3k Sec16b |
Mortality from cardiovascular disease among interregional migrants in England and Wales
[ PUBLICATION ]
OBJECTIVE: To investigate the extent to which geographical variations in mortality from ischaemic heart disease and stroke in Britain are influenced by factors in early life or in adulthood.
DESIGN: Longitudinal study of migrants.
SUBJECTS: 1% sample of residents in England and Wales born before October 1939 and enumerated at the 1971 census (the Office of Population Censuses and Surveys' longitudinal study).
MAIN OUTCOME MEASURE: 18,221 deaths from ischaemic heart disease and 9899 ...
| Known for Cardiovascular Disease | Greater London | England Wales | Geographical Variations | Interregional Migrants |
Key People For Lung Function
David Peter Strachan:Expert Impact
Concepts for whichDavid Peter Strachanhas direct influence:Lung function, International study, Air pollution, Atopic eczema, Greater london, Blood pressure, Uk biobank, Genetic loci.
David Peter Strachan:KOL impact
Concepts related to the work of other authors for whichfor which David Peter Strachan has influence:Atopic dermatitis, Allergic rhinitis, Lung function, Genetic variants, Air pollution, Blood pressure, Type 2 diabetes.
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