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  • Lymphangioleiomyomatosis

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#1
Joel Moss
Joel Moss
From the Pathology Section (K.M., W.K.N., V.J.F.) and Pulmonary–Critical Care Medicine Branch (P.M.B., J.B., J.M.), National Heart, Lung and Blood Institute, National ...
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Cholera Toxin | Adenylate Cyclase | Tuberous Sclerosis Complex | Lam Cells
#2
Angelo M. Taveira‐DaSilva
Angelo M. Taveira‐DaSilva
National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA
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Lung Function | Chylous Effusions | Benign Metastasizing Leiomyoma | Lam Cells

#3
Francis X. McCormack
Francis X. McCormack
Medicine, Division of Pulmonary and Critical Care Medicine, University of Cincinnati, Cincinnati, OH
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Surfactant Protein | Tuberous Sclerosis Complex | Cystic Lung | Alveolar Macrophages
#4
KUNIAKI SEYAMA
KUNIAKI SEYAMA
1Department of Respiratory Medicine, Juntendo University School of Medicine, Tokyo; and 2Kagome Research Institute, Kagome, Nasu-gun, Tochigi, Japan
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Birt-Hogg-Dubé Syndrome | Pulmonary Cysts | Smoking Cessation | Lam Cells
#5
Simon Richard Johnson
Simon Richard Johnson
Nottingham NIHR Biomedical Research Centre, Nottingham MRC Molecular Pathology Node, Division of Respiratory Medicine, University of Nottingham, Nottingham University ...
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Tuberous Sclerosis Complex | Airway Smooth Muscle | Lung Function | Mmp Activity
#6
Elizabeth Petri Henske
Elizabeth Petri Henske
Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA D.J. Kwiatkowski and E.P. Henske contributed equally ...
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Tuberous Sclerosis Complex | Tsc2-Deficient Cells | Mammalian Target | Renal Angiomyolipomas
#7
Mario P. Stylianou
Mario P. Stylianou
(1) Mount Sinai Medical Center, Miami Beach, FL, USA (2) National Heart, Lung and Blood Institute, Bethesda, MD, USA (3) Palmer Center for Chiropractic Research, Davenport, ...
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Lung Function | Native Diabetics | Mucus Slurper | Marfan Syndrome
#8
Nilo A. Avila
Nilo A. Avila
Clinical Center Diagnostic Radiology Department, National Institutes of Health, Bethesda, Maryland.
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Congenital Adrenal Hyperplasia | Testicular Adrenal Rest Tissue | Pulmonary Fibrosis | Diurnal Variation
#9
Wendy K. Steagall*
Wendy K. Steagall*
Pulmonary-Critical Care Medicine Branch, National Institutes of Health, Bethesda, Maryland 20892-1590.
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Lam Cells | Tsc2 Loss | Pulmonary Function | Cystic Fibrosis
#10
Kazuhisa Takahashi
Kazuhisa Takahashi
Department of Orthopedic Surgery, Graduate School of Medicine, Chiba University School of Medicine, Chiba University, Chiba, Japan
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Lung Cancer | Nucleus Pulposus | Drg Neurons | Lumbar Spine
#11
Gustavo Pacheco–Rodriguez
Gustavo Pacheco–Rodriguez
Pulmonary-Critical Care Medicine Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
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Lam Cells | Brefeldin A-Inhibited Guanine Nucleotide-Exchange | Adp-Ribosylation Factor | Sec7 Domain
#12
Keiko Mitani
Keiko Mitani
Department of Pathology, Juntendo University, Graduate School of Medicine, Tokyo
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Lam Cells | Lung Adenocarcinoma | Multifocal Micronodular Pneumocyte Hyperplasia | Oncocytic Mucoepidermoid Carcinoma
#13
Toshio Kumasaka
Toshio Kumasaka
Department of Pathology, Japanese Red Cross Medical Center, Japan The Study Group of Pneumothorax and Cystic Lung Diseases, Japan
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Lung Cancer | Lam Cells | Pulmonary Nodules | Multifocal Micronodular Pneumocyte Hyperplasia
#14
Souheil Y. El-Chemaly
Souheil Y. El-Chemaly
American University of Beirut, Faculty of Health Sciences, P.O. Box, 113-7098, Lebanon
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Pulmonary Fibrosis | Lung Transplantation | Short Telomeres | Telomere Length
#15
Lisa R. Young
Lisa R. Young
Division of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229-3039, USA
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Interstitial Lung | Pulmonary Fibrosis | Hermansky-Pudlak Syndrome | Trial Participation
#16
Yoshikazu Inoue
Yoshikazu Inoue
The Second Department of Internal Medicine, Ehime University School of Medicine, Ehime, 791-02, Japan
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Idiopathic Pulmonary Fibrosis | Interstitial Lung | Autoimmune Pulmonary Alveolar Proteinosis | Acute Exacerbation
#17
Sergio Harari
Sergio Harari
U.O. di Pneumologia e Terapia Semi-Intensiva Respiratoria, Servizio di Fisiopatologia Respiratoria e Emodinamica Polmonare, Ospedale San Giuseppe, MultiMedica IRCCS, Milan, ...
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Idiopathic Pulmonary Fibrosis | Pulmonary Hypertension | Interstitial Lung | Air Pollution

 

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A National Registry On Clinical Manifestations, Genetics, Interventions, And...

[ CLINICAL_TRIAL ] Pulmonary lymphangioleiomyomatosis (LAM), a disease characterized by diffuse cystic changes in the lung, is a rare disorder that affects almost exclusively women. The main objectives of this ...
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Rare Disorder | Diffuse Cystic | Lam Characterized | Exclusively Women

The Tolerability Of Saracatinib In Subjects With Lymphangioleiomyomatosis (Lam)...

[ CLINICAL_TRIAL ] Lymphangioleiomyomatosis (LAM) is a rare lung disease that mostly affects women of childbearing age. In LAM, abnormal, muscle-like cells begin to grow out of control in the lungs. As a result, ...
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Drug Saracatinib | Lungs Lam | Manual Operations | Hospitalization Severe

Safety And Efficacy Of Saracatinib In Subjects With Lymphangioleiomyomatosis....

[ CLINICAL_TRIAL ] This study is being done to determine if there is a potential benefit of saracatinib in LAM subjects. Based on the information of this trial, additional clinical development trials will be ...
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Src Cells | Saracatinib Lam | Receptor Kinases

Serum Vegf-D Concentration As A Biomarker Of Lymphangioleiomyomatosis Severity...

[ PUBLICATION ] ... with lymphangioleiomyomatosis, a rare neoplasm associated with mTOR-activating tuberous sclerosis gene mutations, lymphadenopathy, metastatic spread, and pulmonary cyst formation. We used ...
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Serum Vegf | Multicenter International Lymphangioleiomyomatosis | Concentrations Baseline | Supplemental Oxygen

Histamine Signaling And Metabolism Identify Potential Biomarkers And Therapies...

[ PUBLICATION ] ... for lymphangioleiomyomatosis (LAM). However, this therapy has variable tolerability and some patients show progressive decline of lung function despite treatment. LAM diagnosis and ...
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Potential Biomarkers | Lam Tumorigenesis | Histamine Signaling | Lung Function

Study Of Breast Cancer Incidence In Patients Of Lymphangioleiomyomatosis

[ PUBLICATION ] ... of lymphangioleiomyomatosis (LAM) to that of metastatic breast cancer. Following on this observation, we assessed the association between LAM and subsequent breast cancer. An ...
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Breast Cancer | Exome Sequence | United Kingdom | Country-Specific Rates

Pulmonary Hypertension In Lymphangioleiomyomatosis: Characteristics In 20 Patients

[ PUBLICATION ] ... with lymphangioleiomyomatosis (LAM) and pre-capillary pulmonary hypertension (PH) by right heart catheterisation. It was conducted in 20 females with a mean ± SD age of 49 ± 12 yrs and a ...
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Pulmonary Hypertension | Pah Therapy | · Cm-5 | Haemodynamic Characteristics

Efficacy And Safety Of Long-Term Sirolimus Therapy For Asian Patients With...

[ PUBLICATION ] ... with lymphangioleiomyomatosis (LAM) treated for a 12-month time period; however the pretreatment decline in lung function after the drug was discontinued indicated that continued exposure ...
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Long-Term Sirolimus | Lung Function | Drug Compliance | Declining Frequency

Melanoma-Associated Antigen Expression In Lymphangioleiomyomatosis Renders Tumor...

[ PUBLICATION ] ... diagnose lymphangioleiomyomatosis, a hyperproliferative disorder of lung smooth muscle cells with mutations in both alleles of either TSC1 or TSC2. A subset of these tumor cells expresses ...
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Tumor Cells | Antigen Expression | Gp100 Reactive | Hyperproliferative Disorder

Correlation Between The Native Lung Volume Change And Postoperative Pulmonary...

[ PUBLICATION ] ... for lymphangioleiomyomatosis because of its increased compliance, there is no study that has reported the details on the change of the native lung volume after single lung transplantation ...
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Single Lung Transplantation | Lung Volume | Postoperative Pulmonary Function | Computed Tomography