• KOL
    • Macular Hole
    • Makoto Inoue
    • Makoto Inoue: Influence Statistics

      Makoto Inoue

      Makoto Inoue

      Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan | Department of Ophthalmology, Kyorin University, Tokyo, Japan | Kyorin Eye Center, Kyorin ...

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      Makoto Inoue:Expert Impact

      Concepts for whichMakoto Inouehas direct influence:Macular hole,Retinal detachment,Model eye,Intraocular lenses,Blood flow,Macular detachment,Vitreous surgery,Subtenon injection.

      Makoto Inoue:KOL impact

      Concepts related to the work of other authors for whichfor which Makoto Inoue has influence:Diabetic retinopathy,Visual acuity,Retinal detachment,Macular hole,Optical coherence,Triamcinolone acetonide,Plana vitrectomy.

      KOL Resume for Makoto Inoue

      Year
      2022

      Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan

      2021

      Department of Ophthalmology, Kyorin University, Tokyo, Japan

      2020

      Kyorin Eye Center, Kyorin University School of Medicine, Tokyo, Japan.

      2019

      Kyorin Eye Center, Kyorin University School of Medicine, 6-20-2 Shinkawa, 181-8611, Mitaka, Tokyo, Japan

      2018

      From the Department of Ophthalmology (Seo, Nam, Lee, Park, Y.J. Kim), Gachon University Gil Hospital, Incheon, the Department of Ophthalmology (S.-W. Kim), Korea University College of Medicine, and the Department of Ophthalmology (Chung), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; the Kyorin Eye Center (Inoue), Kyorin University School of Medicine, Mitaka, Tokyo, Japan; the Department of Ophthalmology (T. Kim), Duke University Eye Center, Durham, North Carolina, USA

      Kyorin Eye Center, Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan.

      2017

      Department of Ophthalmology, Kyorin University School of Medicine, 6-20-2 Shinkawa, 181-8611, Mitaka, Tokyo, Japan

      2016

      Department of Ophthalmology, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka, 181-8611, Tokyo, Japan

      2015

      Kyorin Eye Center, Kyorin University School of Medicine, Tokyo - Japan

      2014

      Kryorin Eye Center, Kryorin University School of Medicine, 6-20-2 Shinkawa, 181-8611, Mitaka, Tokyo, Japan

      2013

      Kyorin Eye Center Kyorin University School of Medicine TokyoJapan

      Departemnt of Ophthalmology, Keio University School of Medicine, Tokyo, Japan

      2012

      Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan.

      Kyorin Eye Center, Kyorin University School of Medicine, Mitaka, Tokyo, Japan

      2011

      Kyorin Eye Center, Kyorin University School of Medicine, Mitaka, Japan

      2010

      Kyorin Eye Center, Kyorin University School of Medicine, Tokyo 181-8611, Japan

      Department of Ophthalmology, Keio University School of Medicine

      2009

      Department of Ophthalmology, Keio University School of Medicine, Kyorin Eye Center, Kyorin University School of Medicine, Tokyo, Department of Ophthalmology, Teikyo University Faculty of Medicine, Oita, Japan

      2008

      From the Department of Ophthalmology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.

      Kyorin Eye Center, Kryorin University, Tokyo, Japan

      2007

      Kyorin Eye Center, Kyorin University School of Medicine, Tokyo, and

      From the Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.

      Department of Ophthalmology, Keio University School of Medicine, Keio University School of Medicine, Tokyo, Japan

      2006

      From the Departments of Ophthalmology,

      2005

      Department of Ophthalmology, Keio University of School of Medicine, 35 Shinanomachi, Shinjyuku-ku, 160-8582, Tokyo, Japan

      2004

      Department of Ophthalmology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.

      2003

      Ophthalmology, Keio University School of Medicine, and

      2002

      *Department of Ophthalmology, Keio University School of Medicine, and the †Department of Pathology, Saiseikai Central Hospital, Tokyo, Japan.

      2001

      Department of Ophthalmology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan

      2000

      Keio University School of Medicine, Tokyo, Japan

      1996

      Department of Ophthalmology, Keio University School of Medicine, Shinjuku-ku, Japan

      1995

      Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.

      Sample of concepts for which Makoto Inoue is among the top experts in the world.
      Concept World rank
      n4 blade design #1
      postoperative deep faz #1
      congenital optic #1
      view vitrectomy #1
      images contact lens #1
      diffractive zm900 #1
      viewed small #1
      resolving optic #1
      cost defect bcva #1
      aberration central #1
      viewing angle lens #1
      x60 iol extension #1
      intrascleral fixation iol #1
      surgery miyake #1
      surface sclerotomy #1
      postoperative retinal #1
      va70 iols #1
      pseudohole aged #1
      distinct incision architecture #1
      311t9 iols #1
      bcva papillofoveal distance #1
      oct tilt #1
      vitrectomy mtm #1
      vitreous surgery removal #1
      mediumreflective bridging tissue #1
      staphyloma decreased #1
      bridging tissue mh #1
      035 logmar units #1
      excised highly #1
      1 month mtm #1
      faz vitrectomy #1
      iol implantation iol #1
      viewing contrast #1
      cost photoreceptor #1
      edf intraocular lens #1
      eye dark ring #1
      observed multifocal #1
      trocarcannula miyakeapple view #1
      mh intraoperative oct #1
      pvd performed #1
      visibility fundus #1
      postoperative faz #1

      Prominent publications by Makoto Inoue

      KOL-Index: 19621

      PURPOSE: To determine whether the postoperative length of the photoreceptor cone outer segment tips (COST) line defect is significantly correlated with best-corrected visual acuity (BCVA) after macular hole closure.

      DESIGN: Retrospective, consecutive, observational case series.

      PARTICIPANTS: Fifty-one eyes of 51 patients with a surgically closed macular hole were studied.

      METHODS: Spectral-domain optical coherence tomography (SD-OCT) was used to obtain images of the foveal area, and the ...

      Known for Cost Defect | Macular Hole | Outer Segment | Visual Acuity | Postoperative Bcva
      KOL-Index: 18755

      PURPOSE: To investigate the retinal neural damage that occurs during inflammation and the therapeutic effects of the angiotensin II type 1 receptor (AT1R) blocker, telmisartan, using a model of endotoxin-induced uveitis (EIU).

      METHODS: The localization of AT1R and AT2R was shown by immunohistochemistry. EIU was induced by intraperitoneal injection of lipopolysaccharide (LPS). Animals were treated with telmisartan for 2 days and were evaluated 24 hours later. Expression levels of ...

      Known for Retinal Inflammation | Type 1 | Neuroprotective Effects | Treatment Telmisartan | Receptor Angiotensin
      KOL-Index: 18524

      PURPOSE: To investigate the involvement of the renin-angiotensin system (RAS) and the nuclear factor (NF)-kappaB pathway with diabetes-induced retinal inflammation.

      METHODS: Six weeks after induction of diabetes, C57BL/6 mice were treated with the angiotensin II type 1 receptor (AT1-R) blocker (ARB) telmisartan or valsartan, the AT2-R blocker PD123319, or the NF-kappaB inhibitor dehydroxymethylepoxyquinomicin (DHMEQ) daily for 1 week. Retinal mRNA and protein levels of the RAS components ...

      Known for Type 1 | Nuclear Factor | Induced Retinal | Messenger Receptor | Protein Levels
      KOL-Index: 16057

      PURPOSE: To evaluate the clinical outcomes after vitrectomy, without gas tamponade or laser photocoagulation to the margin of the optic nerve, for the treatment of macular detachment associated with optic disc pits and to characterize retinal manifestations during treatment of optic pit maculopathy using optical coherence tomography (OCT).

      DESIGN: Noncomparative, retrospective, interventional case series.

      PARTICIPANTS: Eight consecutive patients (8 to 56 years of age) with unilateral ...

      Known for Macular Detachment | Gas Tamponade | Optic Disc Pit | Laser Treatment | Vitrectomy Induction
      KOL-Index: 15380

      PURPOSE: To examine whether the angiotensin II type 1 receptor (AT1-R) signaling plays a role in ocular inflammation in endotoxin-induced uveitis (EIU).

      METHODS: EIU was induced in C57BL/6 mice by a single intraperitoneal injection of 150 mug lipopolysaccharide (LPS). Tissue localization, mRNA expression, and protein levels of AT1-R in murine retinas were examined by immunohistochemistry, RT-PCR, and Western blot analyses, respectively. Telmisartan, an AT1-R antagonist widely used as an ...

      Known for Ocular Inflammation | Type 1 | Induced Uveitis | Leukocyte Adhesion | Protein Levels
      KOL-Index: 15024

      PURPOSE: A recent study revealed that angiotensin receptor signaling mediates ocular inflammation and neovascularization. It was also found that prorenin undergoes nonproteolytic activation leading to upregulation of the renin-angiotensin system (RAS) when prorenin receptor interacts specifically with the handle region of prorenin. The purpose of the present study was to elucidate the role of the receptor-dependent nonproteolytic activation of prorenin in ocular inflammation in ...

      Known for Ocular Inflammation | Prorenin Receptor | Nonproteolytic Activation | Induced Uveitis | Leukocyte Adhesion
      KOL-Index: 14600

      PURPOSE: To determine whether a recovery of the microstructures of the foveal photoreceptors after macular hole closure is correlated with best-corrected visual acuity (BCVA).

      DESIGN: Retrospective, consecutive, observational case series.

      METHODS:

      SETTING: Single-center academic practice.

      STUDY POPULATION: Forty-one eyes of 41 patients with surgically closed macular holes. OBSERVATIONAL PROCEDURES: The presence and intactness of the cone outer segment tips (COST) line were determined by ...

      Known for Visual Acuity | Macular Hole Surgery | Foveal Cone | Eyes Bcva | 12 Months
      KOL-Index: 14452

      PURPOSE: Angiotensin-converting enzyme (ACE), also known as kininase II, functions not only to convert angiotensin I to angiotensin II, but also to cleave bradykinin into inactive fragments. Thus, ACE inhibition causes the tissue accumulation of bradykinin, exerting either of two opposite effects: anti- or proangiogenic. The purpose of the present study was to investigate the role of bradykinin in the development of choroidal neovascularization (CNV), with or without ACE ...

      Known for Choroidal Neovascularization | Converting Enzyme | Cnv Vegf | Receptor Angiotensin | Inbred C57bl Microscopy
      KOL-Index: 13919

      BACKGROUND: To determine whether the status of a macular hole can be determined by spectral-domain optical coherence tomography in gas-filled eyes.

      DESIGN: Prospective study, university hospital setting.

      PARTICIPANTS: Twenty-six eyes with a macular hole, seven eyes with a macular hole retinal detachment and four eyes with a macular hole and myopic traction maculopathy underwent vitreous surgery.

      METHODS: The macular area was examined by spectral-domain optical coherence tomography ...

      Known for Macular Hole | Optical Coherence | Eyes Day | Postoperative Status | Hexafluoride Tomography
      KOL-Index: 13754

      PURPOSE: To investigate the structural abnormalities of optic disc pits and colobomas by swept-source optical coherence tomography (OCT).

      METHODS: Sixteen eyes with congenital optic disc pits, and seven eyes with optic disc colobomas were studied. Papillary and peripapillary areas were examined with swept-source OCT. The entire course of the pit or cavity and the spatial relationship between pits and retrobulbar subarachnoid space (SAS) were examined.

      RESULTS: Optical coherence ...

      Known for Optic Disc | Coherence Tomography | Source Oct | Lamina Cribrosa | Sixteen Eyes
      KOL-Index: 13473

      PURPOSE: To determine whether there is a significant correlation between the integrity of the foveal microstructures and the best-corrected visual acuity (BCVA) after pars plana vitrectomy for epiretinal membrane (ERM) removal.

      METHODS: This was a retrospective, interventional case series. Forty-six eyes of 45 patients with an ERM underwent vitrectomy. The foveal area was examined by spectral-domain-optical coherence tomography (SD-OCT) preoperatively and postoperatively. The correlation ...

      Known for Epiretinal Membrane | Outer Segment | Bcva Length | Cost Defect | Visual Recovery
      KOL-Index: 13162

      Interleukin (IL)-6, a potent proinflammatory cytokine, is suggested to be a risk factor for choroidal neovascularization (CNV) because of its increased levels in the serum of patients with age-related macular degeneration; however, the role of IL-6 in CNV has not been defined. The present study reveals the critical contribution of IL-6 signaling and its downstream STAT3 pathway to the murine model of laser-induced CNV. CNV induction by laser treatment stimulated IL-6 expression in the ...

      Known for Choroidal Neovascularization | Il6 Cnv | Signal Transducer | Agerelated Macular Degeneration | Stat3 Activation
      KOL-Index: 13041

      PURPOSE: To investigate the anti-inflammatory and anti-angiogenic effects of telmisartan, an angiotensin II type 1 receptor (AT1-R) antagonist, on ischemia-induced retinal neovascularization.

      METHODS: C57BL/6 neonatal mice were reared in an 80% concentration of oxygen from postnatal day (P)7 to P12, followed by room-air breathing until P17, to induce ischemia-initiated retinal neovascularization (i.e., a murine model of ischemic retinopathy). Tissue localization of AT1-R was examined by ...

      Known for Type 1 | Retinal Neovascularization | Messenger Receptor | Physiologic Rna | Vascular Endothelial
      KOL-Index: 12691

      PURPOSE: To investigate the matrix metalloproteinase (MMP) species and their activation associated with the pathogenesis of proliferative diabetic retinopathy (PDR).

      METHODS: Sandwich enzyme immunoassays were used to measure concentrations of MMP-1, -2, -3, -7, -8, -9, and -13 in vitreous samples from patients with PDR and nondiabetic vitreoretinal diseases. To evaluate activation ratios of the zymogen of MMP-2 (proMMP-2) and -9 (proMMP-9) in the vitreous samples and fibrovascular ...

      Known for Matrix Metalloproteinase | Fibrovascular Tissues | Vitreous Samples | Mmp2 Mt1mmp | Diabetic Retinopathy
      KOL-Index: 12295

      PURPOSE: To evaluate the effect of vitrectomy on the best-corrected visual acuity (BCVA) and postoperative complications in highly myopic eyes with myopic traction maculopathy.

      METHODS: The medical records of 71 eyes of 64 patients with myopic traction maculopathy and high myopia (≤-8.0 diopters and axial length, ≥26.0 mm) were reviewed. Twenty-six eyes had only macular retinoschisis, 30 eyes had foveal detachment, and 15 eyes had macular hole. The BCVA and complications were studied in ...

      Known for Myopic Traction | Membrane Peeling | Macular Retinoschisis | Foveal Detachment | Internal Limiting

      Key People For Macular Hole

      Top KOLs in the world
      #1
      William E Smiddy
      visual acuity macular hole retinal detachment
      #2
      Alain Gaudric
      macular edema optical coherence diabetic retinopathy
      #3
      Robert T Wendel
      pneumatic retinopexy macular hole cilioretinal artery
      #4
      J Donald M Gass
      visual acuity macular holes fluorescein angiography
      #5
      Neil E Kelly
      pneumatic retinopexy macular holes vitreous surgery
      #6
      Pascale Massin
      diabetic retinopathy macular edema visual acuity

      Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan | Department of Ophthalmology, Kyorin University, Tokyo, Japan | Kyorin Eye Center, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka, 181-8611, Tokyo, Japan

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