Yoichi Nakazato: Influence Statistics

Yoichi Nakazato

Yoichi Nakazato

Department of Pathology, Hidaka Hospital, Gunma 3700001, Japan;, nakazato_yoichi@gunma-u.ac.jp | Department of Pathology, Hidaka Hospital, 886 Nakao-machi, 370-0001, Takasaki, ...

Yoichi Nakazato: Expert Impact

Concepts for which Yoichi Nakazato has direct influence: Central nervous , Oligodendroglial tumors , Schwann cells , Brain tumors , Diffuse plaques , Tumor cells , Diffuse astrocytomas .

Yoichi Nakazato: KOL impact

Concepts related to the work of other authors for which for which Yoichi Nakazato has influence: Central nervous , Alzheimer disease , Spinal cord , Amyotrophic lateral sclerosis , Neurofibrillary tangles , Tumor cells , Pineal region .

KOL Resume for Yoichi Nakazato

Year
2022

Department of Pathology, Hidaka Hospital, Gunma 3700001, Japan;,

2021

Department of Pathology, Hidaka Hospital, 886 Nakao-machi, 370-0001, Takasaki, Gunma, Japan

2020

6Department of Pathology, Hidaka Hospital, Gunma, Japan; and.

2019

Department of Neurosurgery and Neuro-oncology, National Cancer Center Hospital, Tokyo, Japan

2017

From the Department of Neurology (S.H.), Gunma Rehabilitation Hospital, Agatsuma; Department of Neurology (S.H.), Gunma University Graduate School of Medicine, Maebashi; Department of Neurosurgery (N.A.), Numata Neurosurgery and Heart Disease Hospital; Department of Pathology (Y.N.), Hidaka Hospital, Takasaki; and Department of Neurology (K.O.), Geriatrics Research Institute and Hospital, Maebashi, Japan.

2016

Department of Pathology Hidaka Hospital Gunma Japan

2015

Department of Pathology, Hidaka Hospital, 886 Nakaomachi, 370-0001, Takasaki City, Gunma, Japan

2014

Department of Human Pathology, Gunma University Graduate School of Medicine, Maebashi, Japan

2013

10Department of Human Pathology, Gunma University Graduate School of Medicine, Gunma; and

Department of Human Pathology, University of Gunma Graduate School of Medicine, 3-39-22, Showa-machi, Maebashi, Gunma 371-8511, Japan

2012

Department of Human Pathology, Gunma University Graduate School of Medicine, 3-39-22, Showa, Maebashi, Gunma 371-8511, Japan

2011

9Department of Human Pathology, Gunma University, Gunma, Japan

Pathology, Gunma University Graduate School of Medicine

Departments of Human Pathology

2010

Department of Human Pathology, Graduate School of Medicine, Gunma University

2009

Department of Human Pathology, Gunma University Graduate School of Medicine, Maebashi 3718511, Japan

2008

Department of Human Pathology, Gunma University Graduate School of Medicine, and

2007

Department of Human Pathology, Gunma University Graduate School of Medicine, Maebashi and

Pathology, Gunma University Graduate School of Medicine, Maebashishi, Gunma, Japan

2006

Department of Pathology, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511, Japan

2005

First Department of Pathology, Gunma University School of Medicine

2004

Department of Human Pathology, Gunma University Graduate School of Medicine, Maebashi,

2003

Department of the First Pathology, Gunma University School of Medicine, Japan, JP

2002

Department of Pathology, Gunma University School of Medicine, Maebashi, Japan, JP

2001

Pathology, Gunma University School of Medicine, Maebashi-shi, Gunma, Japan

First Department of Pathology

Prominent publications by Yoichi Nakazato

KOL-Index: 14278 . Abnormal neuronal aggregates of α-internexin and the three neurofilament (NF) subunits, NF-L, NF-M, and NF-H have recently been identified as the pathological hallmarks of neuronal intermediate filament (IF) inclusion disease (NIFID), a novel neurological disease of early onset with a variable clinical phenotype including frontotemporal dementia, pyramidal and extrapyramidal signs. ...
Known for Neurodegenerative Diseases | Inclusion Disease | Neuronal Intermediate | Α Internexin
KOL-Index: 11463 . Evidence has been accumulated that glioblastoma cells release and exploit glutamate for proliferation and migration by autocrine or paracrine loops through Ca2+-permeable AMPA-type glutamate receptors. Here, we show that Ca2+ signaling mediated by AMPA receptor regulates the growth and motility of glioblastoma cells via activation of Akt. Ca2+ supplied through Ca2+-permeable AMPA receptor ...
Known for Ampa Receptor | Human Glioblastoma | Proliferation Migration | Tumor Cells
KOL-Index: 11097 . Abstract. We examined the brains of Tg2576 transgenic mice carrying human amyloid precursor protein with the Swedish mutation and Alzheimer's disease (AD) by means of immunohistochemistry and electron microscopy to clarify the characteristics of amyloid-associated pathology in the transgenic mice. In 12- to 29-month-old Tg2576 mice, congophilic cored plaques in the neocortex and ...
Known for Transgenic Mice | Cored Plaques | Dystrophic Neurites | Activated Microglia
KOL-Index: 10576 . We compared the ultrastructure between diffuse and primitive plaques in the brains of senile dementia, using pairs of routine electron microscopic ultrathin sections and adjacent semithin sections, which were immunolabeled for β protein. In the frontal cortex, amyloid fibrils were rarely seen in a minority of diffuse plaques, suggesting an initial stage of the diffuse plaques. A majority ...
Known for Diffuse Plaques | Senile Dementia | Alzheimer Type | Amyloid Fibrils
KOL-Index: 10473 . One of the type VI intermediate filament proteins, nestin, is expressed in neuroepithelial stem cells during neural embryogenesis. Nestin is also expressed in a variety of neoplasms. Its expression in brain tumors has not been thoroughly studied. The objectives of this study were to survey nestin expression in different types of brain tumor, and to evaluate nestin as a marker for diagnosis ...
Known for Nestin Expression | Brain Tumors | Grade Gliomas | Pathological Diagnosis
KOL-Index: 10417 . Abstractp73 protein, a member of the p53 family protein, induce p21 and MDM2 transcription. In some carcinomas, the expression of p73 was higher in carcinoma than in normal tissue, and the overexpression was correlated to grade, stage or prognosis. However, either the expression of p73 protein or the relationship among p73, p21 and MDM2 proteins was not known well in glioma. In this study, ...
Known for P73 P21 | Mdm2 Proteins | Tumor Type | Proto Oncogene
KOL-Index: 10077 . Neuronal intermediate filament (IF) inclusion disease (NIFID) is a novel neurological disease of early onset with a variable clinical phenotype including frontotemporal dementia, pyramidal, and extrapyramidal signs. Pathologically, in affected areas, there is neuronal loss, astrocytosis, and neuronal intracytoplasmic aggregates of abnormal neuronal IFs that contain neither tau nor ...
Known for Inclusion Disease | Intermediate Filament | Neuronal Proteins | Frontotemporal Dementia
KOL-Index: 9925 . Recently, it was reported that ependymoblastoma and embryonal tumor with abundant neuropil and true rosettes (ETANTR) show 19q13.42 amplification at a high frequency, suggesting that these tumors may constitute a single entity. As ependymoblastic rosettes are the most prominent features in both subtypes, embryonal tumor with multilayered rosettes (ETMR) was proposed, for which 19q13.42 ...
Known for Multilayered Rosettes | 19q1342 Amplification | Brain Tumors | Etantr Ependymoblastoma
KOL-Index: 9842 . PurposeGlioblastoma (GBM) is one of the worst cancers in terms of prognosis. Standard therapy consists of resection with concomitant chemoradiotherapy. Resistance to nimustine hydrochloride (ACNU), an alkylating agent, has been linked to methylguanine DNA methyltransferase (MGMT). Daily administration of procarbazine (PCZ) has been reported to decrease MGMT activity. This study ...
Known for Acnu Patients | Nimustine Hydrochloride | Anaplastic Astrocytoma | Standard Therapy
KOL-Index: 9479 . The Golgi apparatus (GA) of the large pyramidal motor neurons in the cerebral cortex (Betz cells), was examined in sixteen patients with sporadic amyotrophic lateral sclerosis (ALS), in one patient with familial ALS (FALS), and in ten non-ALS age matched controls including one patient with Huntington's disease and one patient with a brain infarct. The GA was immunostained with an antibody ...
Known for Betz Cells | Golgi Apparatus | Lateral Sclerosis | Motor Neurons
KOL-Index: 9326 . Immunohistochemical localization of S-100 protein, its α andβ subunits, and glial fibrillary acidic protein (GFAP) in normal and neoplastic salivary glands was studied by the peroxidase-antiperoxidase method and immunoblot analysis. Positive immunostaining for S-100 protein was observed in pleomorphic adenoma, adenolymphoma, tubular adenoma, adenoid cystic carcinoma, acinic cell tumour, ...
Known for Salivary Gland | S100 Protein | Fibrillary Acidic | Immunohistochemical Distribution
KOL-Index: 9228 . BACKGROUND: Recently described neuronal intermediate filament inclusion disease (NIFID) shows considerable clinical heterogeneity. OBJECTIVE: To assess the spectrum of the clinical and neuropathological features in 10 NIFID cases. METHODS: Retrospective chart and comprehensive neuropathological review of these NIFID cases was conducted. RESULTS: The mean age at onset was 40.8 (range 23 to ...
Known for Neuronal Intermediate | Inclusion Disease | Ftd Mnd | Nifid Cases
KOL-Index: 9190 . Nestin is one of the intermediate filaments abundantly produced in the developing central nervous system and somites in the embryonic stage. Nestin is also reportedly detected in gliomas/glioblastomas. We retested nestin expression in brain tumors having a range of malignancy grades using immunostaining. The intensity of nestin immunostaining roughly paralleled the malignancy grade of the ...
Known for Endothelial Cells | Proliferative Endothelium | Nestin Marker | Brain Tumors

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Department of Pathology, Hidaka Hospital, Gunma 3700001, Japan;, nakazato_yoichi@gunma-u.ac.jp | Department of Pathology, Hidaka Hospital, 886 Nakao-machi, 370-0001, Takasaki, Gunma, Japan | Hidaka Center for Pathologic Diagnosis and Research, Hidaka